|
GB771147A
(en)
|
1954-06-04 |
1957-03-27 |
Merck & Co Inc |
Derivatives of urea
|
|
ZA6706928B
(enExample)
|
1967-03-23 |
|
|
|
|
CH493195A
(de)
|
1968-01-23 |
1970-07-15 |
Ciba Geigy |
Schädlingsbekämpfungsmittel
|
|
GB1195672A
(en)
|
1968-02-01 |
1970-06-17 |
Mobil Oil Corp |
Novel Urea Derivatives and Herbicides containing the same
|
|
CH498859A
(de)
|
1968-07-17 |
1970-11-15 |
Agripat Sa |
Verfahren zur Herstellung von Thiadiazolyl-harnstoffen
|
|
GB1318291A
(en)
|
1970-04-15 |
1973-05-23 |
Shell Int Research |
Carboxamide derivatives and fungicidal compositions containing them
|
|
NL7106557A
(enExample)
|
1970-06-15 |
1971-12-17 |
|
|
|
IL72093A0
(en)
|
1983-06-20 |
1984-10-31 |
Lilly Co Eli |
N'-substituted(3-alkyl-5-isothiazolyl)urea derivatives
|
|
IE68593B1
(en)
|
1989-12-06 |
1996-06-26 |
Sanofi Sa |
Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
|
|
US5145684A
(en)
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
US6579314B1
(en)
|
1995-03-10 |
2003-06-17 |
C.R. Bard, Inc. |
Covered stent with encapsulated ends
|
|
AU1735497A
(en)
|
1996-02-26 |
1997-09-10 |
Sumitomo Pharmaceuticals Company, Limited |
Sulfonylureidopyrazole derivatives
|
|
US6262096B1
(en)
|
1997-11-12 |
2001-07-17 |
Bristol-Myers Squibb Company |
Aminothiazole inhibitors of cyclin dependent kinases
|
|
DE69834052T2
(de)
|
1997-11-14 |
2006-11-02 |
Kowa Co., Ltd., Nagoya |
Neue amidverbindungen und medikamente die diese enthalten
|
|
GT199900147A
(es)
|
1998-09-17 |
1999-09-06 |
|
1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
|
|
GB9823873D0
(en)
|
1998-10-30 |
1998-12-30 |
Pharmacia & Upjohn Spa |
2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents
|
|
CN1332726A
(zh)
|
1998-11-02 |
2002-01-23 |
卫福有限公司 |
吡咯烷化合物及其药物用途
|
|
US6500817B1
(en)
|
1999-03-08 |
2002-12-31 |
Bayer Aktiengesellschaft |
Thiazolyl urea derivatives and their utilization as antiviral agents
|
|
US6610846B1
(en)
|
1999-03-29 |
2003-08-26 |
Hoffman-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
HK1046139B
(zh)
|
1999-03-29 |
2004-12-10 |
霍夫曼-拉罗奇有限公司 |
葡糖激酶活化剂
|
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
|
US6503949B1
(en)
|
1999-05-17 |
2003-01-07 |
Noro Nordisk A/S |
Glucagon antagonists/inverse agonists
|
|
BR0012068A
(pt)
|
1999-06-30 |
2002-05-14 |
Daiichi Seiyaku Co |
Compostos inibidores de vla-4
|
|
DE60008550T2
(de)
|
1999-09-09 |
2004-08-05 |
Kumiai Chemical Industry Co., Ltd. |
Pyrimidinderivate und herbizide welche diese enthalten
|
|
US6353111B1
(en)
|
1999-12-15 |
2002-03-05 |
Hoffmann-La Roche Inc. |
Trans olefinic glucokinase activators
|
|
PL357099A1
(en)
|
2000-02-07 |
2004-07-12 |
Abbott Gmbh & Co.Kg |
2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
|
|
US6608038B2
(en)
|
2000-03-15 |
2003-08-19 |
Novartis Ag |
Methods and compositions for treatment of diabetes and related conditions via gene therapy
|
|
EP1282612B1
(en)
|
2000-05-03 |
2004-12-29 |
F. Hoffmann-La Roche Ag |
Alkynyl phenyl heteroaromatic glucokinase activators
|
|
ATE304011T1
(de)
|
2000-05-03 |
2005-09-15 |
Hoffmann La Roche |
Hydantoin-enthaltende glucokinase aktivatoren
|
|
MXPA02010795A
(es)
|
2000-05-08 |
2003-03-27 |
Hoffmann La Roche |
Activadores de glucocinasa de fenilamida sustituida por para-amino.
|
|
BR0110704A
(pt)
|
2000-05-08 |
2003-01-28 |
Hoffmann La Roche |
Fenil - acetamidas substituìdas e seu uso como ativadores de glicocinase
|
|
CA2416229C
(en)
|
2000-07-20 |
2007-09-18 |
F. Hoffmann-La Roche Ag |
Alpha-acyl and alpha-heteroatom-substituted benzene acetamide glucokinase activators
|
|
US6645990B2
(en)
|
2000-08-15 |
2003-11-11 |
Amgen Inc. |
Thiazolyl urea compounds and methods of uses
|
|
US20020173507A1
(en)
|
2000-08-15 |
2002-11-21 |
Vincent Santora |
Urea compounds and methods of uses
|
|
EP1341774B1
(en)
|
2000-12-06 |
2006-02-01 |
F. Hoffmann-La Roche Ag |
Fused heteroaromatic glucokinase activators
|
|
UA76977C2
(en)
|
2001-03-02 |
2006-10-16 |
Icos Corp |
Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers
|
|
US6881746B2
(en)
|
2001-12-03 |
2005-04-19 |
Novo Nordick A/S |
Glucagon antagonists/inverse agonists
|
|
KR101018318B1
(ko)
|
2001-12-21 |
2011-03-04 |
노보 노르디스크 에이/에스 |
Ｇｋ 활성제로서의 아미드 유도체
|
|
CA2744893A1
(en)
|
2002-06-27 |
2004-01-08 |
Novo Nordisk A/S |
Aryl carbonyl derivatives as glucokinase activators
|
|
WO2004076420A1
(ja)
|
2003-02-26 |
2004-09-10 |
Banyu Pharmaceutical Co., Ltd. |
ヘテロアリールカルバモイルベンゼン誘導体
|
|
US7111188B2
(en)
|
2003-07-31 |
2006-09-19 |
International Business Machines Corporation |
Dynamically configurable fault tolerance in autonomic computing with multiple service points
|
|
BRPI0506662B8
(pt)
|
2004-01-06 |
2021-05-25 |
Novo Nordisk As |
compostos ativadores de glucoquinase
|
|
EP1721314A1
(en)
|
2004-02-26 |
2006-11-15 |
Koninklijke Philips Electronics N.V. |
Multiple-spiral hybrid disc for e-book applications
|
|
US7514448B2
(en)
|
2004-04-02 |
2009-04-07 |
Vertex Pharmaceuticals Incorporated |
Azaindoles useful as inhibitors of rock and other protein kinases
|
|
EP1758611A2
(en)
|
2004-06-17 |
2007-03-07 |
Novo Nordisk A/S |
Use of liver-selective glucokinase activators
|
|
AU2005291810B2
(en)
|
2004-10-07 |
2011-12-08 |
Stem Cell Therapeutics Corp. |
Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds
|
|
WO2006110809A2
(en)
|
2005-04-12 |
2006-10-19 |
Elan Pharma International, Limited |
Nanoparticulate lipase inhibitor formulations
|
|
US20100028439A1
(en)
|
2005-05-23 |
2010-02-04 |
Elan Pharma International Limited |
Nanoparticulate stabilized anti-hypertensive compositions
|
|
JP2009500378A
(ja)
|
2005-07-08 |
2009-01-08 |
ノボ・ノルデイスク・エー／エス |
グルコキナーゼ活性化剤としてのジシクロアルキルカルバモイル尿素
|
|
JP2009500377A
(ja)
|
2005-07-08 |
2009-01-08 |
ノボ・ノルデイスク・エー／エス |
ジシクロアルキルウレア型グルコキナーゼ活性化剤
|
|
JP4960355B2
(ja)
|
2005-07-14 |
2012-06-27 |
ノボ・ノルデイスク・エー／エス |
ウレア型グルコキナーゼ活性化剤
|
|
JP5419706B2
(ja)
|
2006-12-20 |
2014-02-19 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼアクチベーター
|
|
JP2010515701A
(ja)
|
2007-01-09 |
2010-05-13 |
ノボ・ノルデイスク・エー／エス |
ウレアグルコキナーゼアクチベーター
|
|
AU2008204530B2
(en)
|
2007-01-11 |
2013-08-01 |
Vtv Therapeutics Llc |
Urea glucokinase activators
|
|
WO2009054251A1
(ja)
|
2007-10-25 |
2009-04-30 |
Sanyo Electric Co., Ltd. |
発電装置
|
|
JP5513492B2
(ja)
|
2008-05-16 |
2014-06-04 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
PT2576524T
(pt)
|
2010-05-26 |
2017-11-17 |
Vtv Therapeutics Llc |
Resumo
|
|
EP2392575A1
(en)
|
2010-06-04 |
2011-12-07 |
LEK Pharmaceuticals d.d. |
A novel synthetic approach to ß-aminobutyryl substituted compounds
|
|
IN2014DN09554A
(enExample)
|
2012-05-17 |
2015-07-17 |
Transtech Pharma Llc |
|
|
CA2903433A1
(en)
*
|
2013-03-04 |
2014-09-12 |
Vtv Therapeutics Llc |
Stable glucokinase activator compositions
|
|
HK1213197A1
(zh)
|
2013-03-04 |
2016-06-30 |
Vtv治疗有限责任公司 |
包括葡糖激酶活化劑的固體組合物及其製備和使用方法
|
|
JP6102611B2
(ja)
|
2013-07-31 |
2017-03-29 |
セイコーエプソン株式会社 |
液体噴射装置及びワイピング方法
|
|
DK3556354T3
(da)
*
|
2016-12-15 |
2025-08-04 |
Hua Medicine Shanghai Ltd |
Oral fremstilling af en glucokinaseaktivator og fremgangsmåde til fremstilling deraf
|
|
CA3093025A1
(en)
|
2018-06-12 |
2019-12-19 |
Vtv Therapeutics Llc |
Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
|
|
US12391658B2
(en)
|
2020-02-18 |
2025-08-19 |
Vtv Therapeutics Llc |
Sulfoxide and sulfone glucokinase activators and methods of use thereof
|
|
CA3181665A1
(en)
|
2020-06-08 |
2021-12-16 |
Jing TENG |
Crystalline forms of {2-[3-cyclohexyl-3-(trans-4-propoxy- cyclohexyl)-ureido]-thiazol-5-ylsulfanyl} -acetic acid and and uses thereof
|
|
US12479808B2
(en)
|
2020-06-08 |
2025-11-25 |
Vtv Therapeutics Llc |
Salts or co-crystals of {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid and uses thereof
|