JP2023530461A5 - - Google Patents

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Publication number
JP2023530461A5
JP2023530461A5 JP2022577629A JP2022577629A JP2023530461A5 JP 2023530461 A5 JP2023530461 A5 JP 2023530461A5 JP 2022577629 A JP2022577629 A JP 2022577629A JP 2022577629 A JP2022577629 A JP 2022577629A JP 2023530461 A5 JP2023530461 A5 JP 2023530461A5
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JP
Japan
Prior art keywords
nucleotide
sequence
dsrna agent
agent according
seq
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Pending
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JP2022577629A
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English (en)
Japanese (ja)
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JP2023530461A (ja
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Priority claimed from PCT/US2021/037748 external-priority patent/WO2021257782A1/en
Publication of JP2023530461A publication Critical patent/JP2023530461A/ja
Publication of JP2023530461A5 publication Critical patent/JP2023530461A5/ja
Priority to JP2025172381A priority Critical patent/JP2026010079A/ja
Pending legal-status Critical Current

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JP2022577629A 2020-06-18 2021-06-17 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法 Pending JP2023530461A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025172381A JP2026010079A (ja) 2020-06-18 2025-10-14 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063040587P 2020-06-18 2020-06-18
US63/040,587 2020-06-18
US202163153983P 2021-02-26 2021-02-26
US63/153,983 2021-02-26
PCT/US2021/037748 WO2021257782A1 (en) 2020-06-18 2021-06-17 XANTHINE DEHYDROGENASE (XDH) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Related Child Applications (1)

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JP2025172381A Division JP2026010079A (ja) 2020-06-18 2025-10-14 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法

Publications (2)

Publication Number Publication Date
JP2023530461A JP2023530461A (ja) 2023-07-18
JP2023530461A5 true JP2023530461A5 (https=) 2024-07-16

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ID=76859777

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JP2022577629A Pending JP2023530461A (ja) 2020-06-18 2021-06-17 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法
JP2025172381A Pending JP2026010079A (ja) 2020-06-18 2025-10-14 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法

Family Applications After (1)

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JP2025172381A Pending JP2026010079A (ja) 2020-06-18 2025-10-14 キサンチンデヒドロゲナーゼ(XDH)iRNA組成物およびその使用方法

Country Status (12)

Country Link
US (2) US11326166B1 (https=)
EP (1) EP4168546A1 (https=)
JP (2) JP2023530461A (https=)
KR (1) KR20230026455A (https=)
CN (1) CN116209760A (https=)
AU (1) AU2021292296A1 (https=)
BR (1) BR112022024420A2 (https=)
CA (1) CA3184289A1 (https=)
IL (1) IL299063A (https=)
MX (1) MX2022015149A (https=)
TW (1) TW202214856A (https=)
WO (1) WO2021257782A1 (https=)

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WO2017019660A1 (en) 2015-07-27 2017-02-02 Alnylam Pharmaceuticals, Inc. Xanthine dehydrogenase (xdh) irna compositions and methods of use thereof
US20240287525A1 (en) 2021-06-17 2024-08-29 Oslo Universitetssykehus Hf Compositions and methods for treating cancer
WO2022269346A2 (en) * 2021-06-21 2022-12-29 Horizon Therapeutics Ireland Dac Compositions and methods of modulating xanthine dehydrogenase
US11629349B2 (en) * 2021-06-21 2023-04-18 Arrowhead Pharmaceuticals, Inc. RNAi agents for inhibiting expression of xanthine dehydrogenase (XDH), pharmaceutical compositions thereof, and methods of use
CN119487190A (zh) * 2022-04-22 2025-02-18 上海舶望制药有限公司 用于抑制黄嘌呤脱氢酶(xdh)的组合物和方法
WO2024140596A1 (zh) * 2022-12-26 2024-07-04 大睿生物医药科技(上海)有限公司 调控XDH基因活性的siRNA分子
WO2024220746A2 (en) 2023-04-21 2024-10-24 Flagship Pioneering Innovations Vii, Llc Rnai agents targeting fatty acid synthase and related methods
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
TW202530409A (zh) * 2023-10-07 2025-08-01 大陸商齊魯製藥有限公司 iRNA組合物及其使用方法
CN120210189A (zh) * 2023-12-27 2025-06-27 苏州吉玛基因股份有限公司 用于抑制XDH的siRNA及其修饰物与应用
WO2025139010A1 (zh) * 2023-12-29 2025-07-03 丽珠医药集团股份有限公司 抑制XDH基因表达的siRNA及其修饰物与应用
WO2025178854A2 (en) 2024-02-19 2025-08-28 Flagship Pioneering Innovations Vii, Llc Rnai agents targeting cideb and related methods
WO2025217275A2 (en) 2024-04-10 2025-10-16 Flagship Pioneering Innovations Vii, Llc Immune cell targeted compositions and related methods
CN121488039A (zh) * 2024-06-05 2026-02-06 迈威(上海)生物科技股份有限公司 一种抑制XDH基因表达的RNAi制剂及其应用
US20260055414A1 (en) * 2024-08-21 2026-02-26 Novo Nordisk A/S Compositions and methods for inhibiting xdh expression
WO2026061399A1 (en) * 2024-09-18 2026-03-26 Chi Wai Wong Rnai agent for inhibiting expression of xanthine dehydrogenase (xdh) and methods of use thereof

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