JP2023518044A5 - - Google Patents
Info
- Publication number
- JP2023518044A5 JP2023518044A5 JP2022555714A JP2022555714A JP2023518044A5 JP 2023518044 A5 JP2023518044 A5 JP 2023518044A5 JP 2022555714 A JP2022555714 A JP 2022555714A JP 2022555714 A JP2022555714 A JP 2022555714A JP 2023518044 A5 JP2023518044 A5 JP 2023518044A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- solvate
- acceptable salt
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025033957A JP2025102771A (ja) | 2020-03-16 | 2025-03-04 | Ｎｌｒｐ３モジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062990363P | 2020-03-16 | 2020-03-16 | |
| US62/990,363 | 2020-03-16 | ||
| PCT/US2021/022397 WO2021188450A1 (en) | 2020-03-16 | 2021-03-15 | Nlrp3 modulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025033957A Division JP2025102771A (ja) | 2020-03-16 | 2025-03-04 | Ｎｌｒｐ３モジュレーター |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023518044A JP2023518044A (ja) | 2023-04-27 |
| JP2023518044A5 true JP2023518044A5 (https=) | 2024-03-18 |
Family
ID=77747550
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022555714A Ceased JP2023518044A (ja) | 2020-03-16 | 2021-03-15 | Ｎｌｒｐ３モジュレーター |
| JP2025033957A Pending JP2025102771A (ja) | 2020-03-16 | 2025-03-04 | Ｎｌｒｐ３モジュレーター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025033957A Pending JP2025102771A (ja) | 2020-03-16 | 2025-03-04 | Ｎｌｒｐ３モジュレーター |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11603375B2 (https=) |
| EP (1) | EP4121059A4 (https=) |
| JP (2) | JP2023518044A (https=) |
| KR (1) | KR20220154165A (https=) |
| CN (1) | CN115605209B (https=) |
| AR (1) | AR121573A1 (https=) |
| AU (1) | AU2021237477A1 (https=) |
| BR (1) | BR112022018480A2 (https=) |
| CA (1) | CA3175729A1 (https=) |
| CL (1) | CL2022002531A1 (https=) |
| CO (1) | CO2022014499A2 (https=) |
| IL (1) | IL296488A (https=) |
| MX (1) | MX2022011576A (https=) |
| PH (1) | PH12022552447A1 (https=) |
| TW (1) | TWI901652B (https=) |
| WO (1) | WO2021188450A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020312800B2 (en) | 2019-07-17 | 2026-04-23 | Zomagen Biosciences Ltd | N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of multiple sclerosis (ms) |
| JP7595642B2 (ja) | 2019-07-17 | 2024-12-06 | ズーマゲン バイオサイエンシーズ エルティーディー | Ｎｌｒｐ３モジュレーター |
| KR20220154165A (ko) | 2020-03-16 | 2022-11-21 | 조마젠 바이오사이언시즈 엘티디 | Nlrp3 조절제 |
| JP7825294B2 (ja) * | 2021-02-10 | 2026-03-06 | ハンジョウ イノゲート ファーマ カンパニー リミテッド | Ｎｌｒｐ３阻害剤としての化合物 |
| CN117247393A (zh) * | 2022-06-17 | 2023-12-19 | 成都百裕制药股份有限公司 | 酰胺衍生物及其制备方法和在医药上的应用 |
| WO2025255532A1 (en) * | 2024-06-07 | 2025-12-11 | Zomagen Biosciences Ltd | Combination therapies |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2119705A1 (en) * | 2008-05-14 | 2009-11-18 | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. | 3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor |
| KR20110073500A (ko) * | 2008-09-08 | 2011-06-29 | 메르크 파텐트 게엠베하 | 오로라 키나아제 억제제로서 마크로사이클릭 피리미딘 |
| CN107207431B (zh) * | 2015-01-13 | 2021-02-09 | 维夫雷昂生物科学有限责任公司 | Ca2+释放激活的Ca2+(CRAC)通道的调节剂及其药物用途 |
| KR102727059B1 (ko) | 2015-02-16 | 2024-11-05 | 더 유니버서티 어브 퀸슬랜드 | 설포닐우레아와 관련 화합물 및 그 용도 |
| FR3046933B1 (fr) * | 2016-01-25 | 2018-03-02 | Galderma Research & Development | Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires |
| CN109071454B (zh) | 2016-02-16 | 2023-02-17 | 昆士兰大学 | 磺酰脲和相关化合物及其用途 |
| ES2940611T3 (es) | 2016-04-18 | 2023-05-09 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP |
| US11597706B2 (en) * | 2016-04-18 | 2023-03-07 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| CA3047336A1 (en) * | 2017-01-23 | 2018-07-26 | Jecure Therapeutics, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
| AU2017416068A1 (en) | 2017-05-24 | 2019-10-31 | The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Novel compounds and uses |
| US11465992B2 (en) | 2017-07-07 | 2022-10-11 | Inflazome Limited | Sulfonamide carboxamide compounds |
| MX2020001776A (es) | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| JP2020531448A (ja) * | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | 新規なスルホンアミドカルボキサミド化合物 |
| EP3697758B1 (en) | 2017-10-17 | 2022-07-06 | Novartis AG | Sulphonamides and compositions thereof for treating conditions associated with nlrp activity |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| WO2019166624A1 (en) * | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| EP3823974A1 (en) * | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche AG | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| CN113056451A (zh) | 2018-10-24 | 2021-06-29 | 诺华股份有限公司 | 用于治疗与nlrp活性相关的病症的化合物和组合物 |
| JP7595642B2 (ja) | 2019-07-17 | 2024-12-06 | ズーマゲン バイオサイエンシーズ エルティーディー | Ｎｌｒｐ３モジュレーター |
| AU2020312800B2 (en) | 2019-07-17 | 2026-04-23 | Zomagen Biosciences Ltd | N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of multiple sclerosis (ms) |
| KR20220154165A (ko) | 2020-03-16 | 2022-11-21 | 조마젠 바이오사이언시즈 엘티디 | Nlrp3 조절제 |
-
2021
- 2021-03-15 KR KR1020227035334A patent/KR20220154165A/ko active Pending
- 2021-03-15 BR BR112022018480A patent/BR112022018480A2/pt not_active Application Discontinuation
- 2021-03-15 WO PCT/US2021/022397 patent/WO2021188450A1/en not_active Ceased
- 2021-03-15 EP EP21770604.3A patent/EP4121059A4/en active Pending
- 2021-03-15 IL IL296488A patent/IL296488A/en unknown
- 2021-03-15 PH PH1/2022/552447A patent/PH12022552447A1/en unknown
- 2021-03-15 AU AU2021237477A patent/AU2021237477A1/en active Pending
- 2021-03-15 AR ARP210100650A patent/AR121573A1/es unknown
- 2021-03-15 CN CN202180035570.2A patent/CN115605209B/zh active Active
- 2021-03-15 MX MX2022011576A patent/MX2022011576A/es unknown
- 2021-03-15 US US17/202,047 patent/US11603375B2/en active Active
- 2021-03-15 JP JP2022555714A patent/JP2023518044A/ja not_active Ceased
- 2021-03-15 CA CA3175729A patent/CA3175729A1/en active Pending
- 2021-03-16 TW TW110109276A patent/TWI901652B/zh active
-
2022
- 2022-09-15 CL CL2022002531A patent/CL2022002531A1/es unknown
- 2022-10-12 CO CONC2022/0014499A patent/CO2022014499A2/es unknown
-
2023
- 2023-02-02 US US18/163,680 patent/US20230183258A1/en not_active Abandoned
- 2023-10-09 US US18/483,397 patent/US20240101571A1/en not_active Abandoned
-
2025
- 2025-03-04 JP JP2025033957A patent/JP2025102771A/ja active Pending
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