JP2023506776A5 - - Google Patents
Info
- Publication number
- JP2023506776A5 JP2023506776A5 JP2022535602A JP2022535602A JP2023506776A5 JP 2023506776 A5 JP2023506776 A5 JP 2023506776A5 JP 2022535602 A JP2022535602 A JP 2022535602A JP 2022535602 A JP2022535602 A JP 2022535602A JP 2023506776 A5 JP2023506776 A5 JP 2023506776A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- formula
- pharmaceutical composition
- section
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962947342P | 2019-12-12 | 2019-12-12 | |
| US62/947,342 | 2019-12-12 | ||
| PCT/US2020/064629 WO2021119503A1 (en) | 2019-12-12 | 2020-12-11 | Controlled-delivery cromakalim prodrugs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023506776A JP2023506776A (ja) | 2023-02-20 |
| JP2023506776A5 true JP2023506776A5 (https=) | 2023-12-18 |
| JP7636742B2 JP7636742B2 (ja) | 2025-02-27 |
Family
ID=76330627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022535602A Active JP7636742B2 (ja) | 2019-12-12 | 2020-12-11 | 制御送達性クロマカリムプロドラッグ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12454539B2 (https=) |
| EP (1) | EP4072543A4 (https=) |
| JP (1) | JP7636742B2 (https=) |
| CN (1) | CN115443132A (https=) |
| AU (1) | AU2020403144A1 (https=) |
| CA (1) | CA3159771A1 (https=) |
| WO (1) | WO2021119503A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021215932A1 (en) * | 2020-02-07 | 2022-09-15 | Mayo Foundation For Medical Education And Research | Improved methods and compositions for cromakalim prodrug therapy |
| EP4384162A4 (en) * | 2021-08-12 | 2025-06-04 | Qlaris Bio, Inc. | Compositions and methods for extended-release bromo-kallim therapy |
| IL320428A (en) | 2022-11-04 | 2025-06-01 | Qlaris Bio Inc | Topical ophthalmic administration of cromolyns |
| CN119970613B (zh) * | 2025-02-10 | 2026-03-03 | 中国人民解放军总医院 | 一种埃他卡林微针及其制备方法 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2986573A (en) | 1961-01-18 | 1961-05-30 | Schering Corp | Method for the treatment of hypertension |
| US3361816A (en) | 1961-02-20 | 1968-01-02 | Schering Corp | Novel therapeutic compounds and processes for their manufacture |
| US3251837A (en) | 1962-09-14 | 1966-05-17 | Pfizer & Co C | Derivatives of 1, 2, 4-benzothiadiazine-1, 1-dioxides |
| US4200640A (en) | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
| IE52935B1 (en) | 1981-04-15 | 1988-04-13 | Leo Pharm Prod Ltd | Pharmaceutical preparation |
| GB8308062D0 (en) | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
| US4616012A (en) | 1983-11-25 | 1986-10-07 | Schering Corporation | Carboxyalkyl dipeptides as antiglaucoma agents |
| US4634698A (en) | 1984-09-24 | 1987-01-06 | Schering Corporation | Antiglaucoma agents |
| GB8730051D0 (en) | 1987-12-23 | 1988-02-03 | Beecham Group Plc | Novel compounds |
| AU628331B2 (en) | 1988-05-06 | 1992-09-17 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
| WO1989010757A1 (en) | 1988-05-10 | 1989-11-16 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis | New ophthalmic preparation for treating glaucoma |
| GB8822743D0 (en) | 1988-09-28 | 1988-11-02 | Beecham Group Plc | Novel compounds |
| GB8927980D0 (en) | 1989-12-11 | 1990-02-14 | Beecham Group Plc | Pharmaceuticals |
| US5565560A (en) | 1991-05-13 | 1996-10-15 | Merck & Co., Inc. | O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
| US5328830A (en) | 1992-09-08 | 1994-07-12 | Miles Inc. | Potassium channel modulators |
| US5965620A (en) | 1993-07-23 | 1999-10-12 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| US6242443B1 (en) | 1996-06-21 | 2001-06-05 | Novo Nordisk Ais | 1,2,4-benzothiadiazine derivatives, their preparation and use |
| FR2767692B1 (fr) | 1997-09-01 | 2000-03-03 | Oreal | Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles |
| AU754965B2 (en) | 1997-12-31 | 2002-11-28 | University Of Kansas, The | Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof |
| US6204257B1 (en) | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
| US7186707B2 (en) | 2002-04-01 | 2007-03-06 | University Of Florida | Prodrugs for use as ophthalmic agents |
| CN101327325A (zh) | 2002-07-30 | 2008-12-24 | 奥默罗斯公司 | 眼科冲洗液及方法 |
| FR2852245B1 (fr) | 2003-03-11 | 2006-08-11 | Utilisation du diazoxide dans le traitement de l'ischemie retinienne | |
| ES2342090T3 (es) | 2004-08-25 | 2010-07-01 | Essentialis, Inc. | Formulaciones farmaceuticas de agentes de apertura de canales de potasio dependientes de atp y usos de los mismos. |
| GB0702972D0 (en) * | 2007-02-15 | 2007-03-28 | Cambridge Entpr Ltd | Induction of autography |
| JP5681723B2 (ja) | 2009-11-20 | 2015-03-11 | ライジェル ファーマシューティカルズ， インコーポレイテッド | ２，４−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用 |
| JP2011136923A (ja) | 2009-12-28 | 2011-07-14 | Lion Corp | ソフトコンタクトレンズ用点眼剤 |
| WO2013130411A1 (en) | 2012-02-27 | 2013-09-06 | Essentialis, Inc. | Salts of potassium atp channel openers and uses thereof |
| DK2838533T3 (da) | 2012-04-16 | 2017-11-27 | Univ Case Western Reserve | Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet |
| US10981951B2 (en) * | 2014-01-31 | 2021-04-20 | Mayo Foundation For Medical Education And Research | Therapeutics for the treatment of glaucoma |
| AU2015296640B2 (en) * | 2014-07-30 | 2020-05-21 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| MA41252A (fr) | 2014-12-23 | 2017-10-31 | Gilead Sciences Inc | Formes solides d'un inhibiteur d'ask 1 |
| WO2018047175A1 (en) | 2016-09-08 | 2018-03-15 | Regenera Pharma Ltd. | Compositions comprising triterpenoids and uses thereof for treating optic neuropathy |
| AU2021215932A1 (en) | 2020-02-07 | 2022-09-15 | Mayo Foundation For Medical Education And Research | Improved methods and compositions for cromakalim prodrug therapy |
-
2020
- 2020-12-11 CA CA3159771A patent/CA3159771A1/en active Pending
- 2020-12-11 JP JP2022535602A patent/JP7636742B2/ja active Active
- 2020-12-11 WO PCT/US2020/064629 patent/WO2021119503A1/en not_active Ceased
- 2020-12-11 EP EP20897717.3A patent/EP4072543A4/en active Pending
- 2020-12-11 AU AU2020403144A patent/AU2020403144A1/en active Pending
- 2020-12-11 CN CN202080095951.5A patent/CN115443132A/zh active Pending
-
2022
- 2022-06-09 US US17/836,871 patent/US12454539B2/en active Active
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