JP2020510085A5 - - Google Patents
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- Publication number
- JP2020510085A5 JP2020510085A5 JP2019570355A JP2019570355A JP2020510085A5 JP 2020510085 A5 JP2020510085 A5 JP 2020510085A5 JP 2019570355 A JP2019570355 A JP 2019570355A JP 2019570355 A JP2019570355 A JP 2019570355A JP 2020510085 A5 JP2020510085 A5 JP 2020510085A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- pharmaceutically acceptable
- pharmaceutical composition
- composition according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 elixirs Substances 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 11
- NCVVTDLFKVYDRI-UHFFFAOYSA-N pentan-2-yl dihydrogen phosphate Chemical compound CCCC(C)OP(O)(O)=O NCVVTDLFKVYDRI-UHFFFAOYSA-N 0.000 claims 6
- 125000004192 tetrahydrofuran-2-yl group Chemical group [H]C1([H])OC([H])(*)C([H])([H])C1([H])[H] 0.000 claims 6
- 239000000243 solution Substances 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- 150000003863 ammonium salts Chemical class 0.000 claims 2
- 159000000007 calcium salts Chemical class 0.000 claims 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical group [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims 2
- 159000000003 magnesium salts Chemical class 0.000 claims 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 159000000000 sodium salts Chemical class 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 150000001868 cobalt Chemical class 0.000 claims 1
- 229910017052 cobalt Inorganic materials 0.000 claims 1
- 239000010941 cobalt Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021115155A JP7315248B2 (ja) | 2017-03-10 | 2021-07-12 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2023111463A JP2023126939A (ja) | 2017-03-10 | 2023-07-06 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2025167137A JP2026009978A (ja) | 2017-03-10 | 2025-10-03 | 抗菌化合物、組成物、及びそれらの使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762470025P | 2017-03-10 | 2017-03-10 | |
| US201762470039P | 2017-03-10 | 2017-03-10 | |
| US62/470,025 | 2017-03-10 | ||
| US62/470,039 | 2017-03-10 | ||
| PCT/US2018/022068 WO2018165673A1 (en) | 2017-03-10 | 2018-03-12 | Antimicrobial compounds, compositions, and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021115155A Division JP7315248B2 (ja) | 2017-03-10 | 2021-07-12 | 抗菌化合物、組成物、及びそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510085A JP2020510085A (ja) | 2020-04-02 |
| JP2020510085A5 true JP2020510085A5 (https=) | 2021-04-08 |
| JP6917078B2 JP6917078B2 (ja) | 2021-08-11 |
Family
ID=63446316
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019570355A Active JP6917078B2 (ja) | 2017-03-10 | 2018-03-12 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2021115155A Active JP7315248B2 (ja) | 2017-03-10 | 2021-07-12 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2023111463A Pending JP2023126939A (ja) | 2017-03-10 | 2023-07-06 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2025167137A Pending JP2026009978A (ja) | 2017-03-10 | 2025-10-03 | 抗菌化合物、組成物、及びそれらの使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021115155A Active JP7315248B2 (ja) | 2017-03-10 | 2021-07-12 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2023111463A Pending JP2023126939A (ja) | 2017-03-10 | 2023-07-06 | 抗菌化合物、組成物、及びそれらの使用 |
| JP2025167137A Pending JP2026009978A (ja) | 2017-03-10 | 2025-10-03 | 抗菌化合物、組成物、及びそれらの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US20210139522A1 (https=) |
| EP (2) | EP3592430B1 (https=) |
| JP (4) | JP6917078B2 (https=) |
| KR (5) | KR102684529B1 (https=) |
| CN (2) | CN110612143B (https=) |
| AU (5) | AU2018230805B2 (https=) |
| BR (2) | BR122021004504B1 (https=) |
| CA (1) | CA3055932A1 (https=) |
| DK (1) | DK3592430T3 (https=) |
| ES (1) | ES2987873T3 (https=) |
| FI (1) | FI3592430T3 (https=) |
| MX (1) | MX391911B (https=) |
| PT (1) | PT3592430T (https=) |
| WO (2) | WO2018165673A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12030908B2 (en) | 2017-03-10 | 2024-07-09 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| US11795192B2 (en) | 2017-03-10 | 2023-10-24 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| SG11202103180QA (en) * | 2018-10-17 | 2021-05-28 | Lakewood Amedex Inc | Methods and compositions for treating oral mucositis |
| EP3980406A4 (en) | 2019-06-06 | 2023-06-28 | Aligos Therapeutics, Inc. | Heterocyclic compounds |
| CN111534458B (zh) * | 2020-04-13 | 2022-01-14 | 浙江工业大学 | 无色杆菌tbc-1及其在降解1,3,6,8-四溴咔唑中的应用 |
| JP2024525259A (ja) * | 2021-07-22 | 2024-07-12 | レイクウッド アメデックス、インコーポレイテッド | ビスホスホシンを調製するための方法 |
| WO2024129985A2 (en) * | 2022-12-14 | 2024-06-20 | Lakewood Amedex, Inc. | Antiviral compounds, compositions, and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4421769A (en) | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
| US5153230A (en) | 1989-10-06 | 1992-10-06 | Perfective Cosmetics, Inc. | Topical skin cream composition |
| US6211162B1 (en) | 1998-12-30 | 2001-04-03 | Oligos Etc. Inc. | Pulmonary delivery of protonated/acidified nucleic acids |
| US6211349B1 (en) * | 1998-12-30 | 2001-04-03 | Oligos Etc., Inc. | Protonated/acidified nucleic acids and methods of use |
| US20020032164A1 (en) * | 1998-12-30 | 2002-03-14 | Dale Roderic M. K. | Antimicrobial compounds and methods for their use |
| US7868162B2 (en) * | 1998-12-30 | 2011-01-11 | Lakewood-Amedex, Inc. | Antimicrobial and antiviral compounds and methods for their use |
| CZ296576B6 (cs) * | 1999-02-12 | 2006-04-12 | Sankyo Company Limited | Nukleosidový analog a oligonukleotidový analog a farmaceutický prostredek, sonda a primer s jeho obsahem |
| US6825348B2 (en) * | 2002-06-25 | 2004-11-30 | Academia Sinica | Antiviral compounds |
| US8227431B2 (en) * | 2008-03-17 | 2012-07-24 | Hetero Drugs Limited | Nucleoside derivatives |
| EP2349209A2 (en) * | 2008-09-26 | 2011-08-03 | Nanobio Corporation | Nanoemulsion therapeutic compositions and methods of using the same |
| CN101724001A (zh) * | 2008-10-24 | 2010-06-09 | 汪明 | 一类药用嘧啶衍生物的合成方法 |
| JP5686736B2 (ja) * | 2008-11-06 | 2015-03-18 | アムビト ビオスシエンセス コルポラチオン | プロテインキナーゼモジュレーターとしてのイミダゾロチアゾール化合物 |
| US8884000B2 (en) * | 2010-02-17 | 2014-11-11 | Albert Einstein College Of Medicine Of Yeshiva University | Saporin-L1 inhibitors and uses thereof |
| EP2601205A2 (en) * | 2010-08-03 | 2013-06-12 | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. | Guanine nucleotide derivatives for treating bacterial infections |
| EP2636677B1 (en) * | 2010-11-02 | 2016-01-13 | SNU R & DB Foundation | Cdk-inhibiting pyrrolopyrimidinone carboxamide derivative or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient for preventing or treating liver cell cancer |
| BR112015009636A8 (pt) * | 2012-10-29 | 2018-04-17 | Cocrystal Pharma Inc | composto, métodos para o tratamento de um hospedeiro infectado, métodos para a prevenção de uma infecção, métodos para a redução da atividade biológica de uma infecção e uso de um composto |
| WO2014124430A1 (en) * | 2013-02-11 | 2014-08-14 | Emory University | Nucleotide and nucleoside therapeutic compositions and uses related thereto |
| WO2015017713A1 (en) * | 2013-08-01 | 2015-02-05 | Idenix Pharmaceuticals, Inc. | D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease |
| US8889701B1 (en) * | 2013-10-11 | 2014-11-18 | Alla Chem, Llc | Substituted (S)-(2R,3R,5R)-3-hydroxy-(5-pyrimidin-1-yl)tetrahydrofuran-2-ylmethyl aryl phosphoramidate |
| FI3638251T3 (fi) * | 2017-06-12 | 2024-04-29 | Lakewood Amedex Inc | Bisfosfosiinin geeliformulaatioita ja niiden käyttötapoja |
-
2018
- 2018-03-12 JP JP2019570355A patent/JP6917078B2/ja active Active
- 2018-03-12 KR KR1020227039954A patent/KR102684529B1/ko active Active
- 2018-03-12 KR KR1020197029037A patent/KR102317158B1/ko active Active
- 2018-03-12 US US16/492,861 patent/US20210139522A1/en not_active Abandoned
- 2018-03-12 KR KR1020257005507A patent/KR20250042167A/ko active Pending
- 2018-03-12 CA CA3055932A patent/CA3055932A1/en active Pending
- 2018-03-12 CN CN201880030624.4A patent/CN110612143B/zh active Active
- 2018-03-12 MX MX2019010695A patent/MX391911B/es unknown
- 2018-03-12 BR BR122021004504-6A patent/BR122021004504B1/pt active IP Right Grant
- 2018-03-12 US US15/919,138 patent/US20180258128A1/en not_active Abandoned
- 2018-03-12 PT PT187631361T patent/PT3592430T/pt unknown
- 2018-03-12 CN CN202110662011.6A patent/CN113476469B/zh not_active Expired - Fee Related
- 2018-03-12 EP EP18763136.1A patent/EP3592430B1/en active Active
- 2018-03-12 KR KR1020217031132A patent/KR102621577B1/ko active Active
- 2018-03-12 DK DK18763136.1T patent/DK3592430T3/da active
- 2018-03-12 WO PCT/US2018/022068 patent/WO2018165673A1/en not_active Ceased
- 2018-03-12 BR BR112019018615-8A patent/BR112019018615B1/pt active IP Right Grant
- 2018-03-12 EP EP23196359.6A patent/EP4272832A3/en active Pending
- 2018-03-12 KR KR1020247022774A patent/KR102772428B1/ko active Active
- 2018-03-12 WO PCT/US2018/022071 patent/WO2018165675A1/en not_active Ceased
- 2018-03-12 AU AU2018230805A patent/AU2018230805B2/en active Active
- 2018-03-12 ES ES18763136T patent/ES2987873T3/es active Active
- 2018-03-12 FI FIEP18763136.1T patent/FI3592430T3/fi active
-
2019
- 2019-07-08 US US16/505,501 patent/US10711028B2/en active Active
- 2019-07-08 US US16/505,497 patent/US10752651B2/en active Active
-
2020
- 2020-07-29 US US16/941,627 patent/US10981943B2/en active Active
-
2021
- 2021-02-26 AU AU2021201251A patent/AU2021201251B2/en active Active
- 2021-07-12 JP JP2021115155A patent/JP7315248B2/ja active Active
-
2022
- 2022-10-20 AU AU2022256175A patent/AU2022256175B2/en active Active
- 2022-10-21 AU AU2022256216A patent/AU2022256216B2/en active Active
-
2023
- 2023-07-06 JP JP2023111463A patent/JP2023126939A/ja active Pending
- 2023-12-20 AU AU2023285791A patent/AU2023285791C1/en active Active
-
2025
- 2025-10-03 JP JP2025167137A patent/JP2026009978A/ja active Pending
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