JP2021191784A5 - - Google Patents
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- Publication number
- JP2021191784A5 JP2021191784A5 JP2021143227A JP2021143227A JP2021191784A5 JP 2021191784 A5 JP2021191784 A5 JP 2021191784A5 JP 2021143227 A JP2021143227 A JP 2021143227A JP 2021143227 A JP2021143227 A JP 2021143227A JP 2021191784 A5 JP2021191784 A5 JP 2021191784A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- acceptable salt
- excipient
- diluent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024098153A JP7658014B2 (ja) | 2019-06-07 | 2024-06-18 | ピロリジン化合物 |
| JP2025052039A JP2025098178A (ja) | 2019-06-07 | 2025-03-26 | ピロリジン化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19382477 | 2019-06-07 | ||
| EP19382477.8 | 2019-06-07 | ||
| JP2021505713A JP6940717B2 (ja) | 2019-06-07 | 2020-06-03 | ピロリジン化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505713A Division JP6940717B2 (ja) | 2019-06-07 | 2020-06-03 | ピロリジン化合物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024098153A Division JP7658014B2 (ja) | 2019-06-07 | 2024-06-18 | ピロリジン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021191784A JP2021191784A (ja) | 2021-12-16 |
| JP2021191784A5 true JP2021191784A5 (https=) | 2023-05-25 |
| JP7508422B2 JP7508422B2 (ja) | 2024-07-01 |
Family
ID=66821161
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505713A Active JP6940717B2 (ja) | 2019-06-07 | 2020-06-03 | ピロリジン化合物 |
| JP2021143227A Active JP7508422B2 (ja) | 2019-06-07 | 2021-09-02 | ピロリジン化合物 |
| JP2024098153A Active JP7658014B2 (ja) | 2019-06-07 | 2024-06-18 | ピロリジン化合物 |
| JP2025052039A Pending JP2025098178A (ja) | 2019-06-07 | 2025-03-26 | ピロリジン化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505713A Active JP6940717B2 (ja) | 2019-06-07 | 2020-06-03 | ピロリジン化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024098153A Active JP7658014B2 (ja) | 2019-06-07 | 2024-06-18 | ピロリジン化合物 |
| JP2025052039A Pending JP2025098178A (ja) | 2019-06-07 | 2025-03-26 | ピロリジン化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US11286249B2 (https=) |
| EP (1) | EP3980409A1 (https=) |
| JP (4) | JP6940717B2 (https=) |
| KR (3) | KR102629923B1 (https=) |
| CN (1) | CN114008021B (https=) |
| AU (1) | AU2020287599B2 (https=) |
| BR (1) | BR112021023347A2 (https=) |
| CL (1) | CL2021003202A1 (https=) |
| CO (1) | CO2021016295A2 (https=) |
| CR (1) | CR20210602A (https=) |
| DO (1) | DOP2021000254A (https=) |
| EA (1) | EA202193007A1 (https=) |
| EC (1) | ECSP21088515A (https=) |
| IL (2) | IL288174B2 (https=) |
| JO (1) | JOP20210319B1 (https=) |
| MA (1) | MA56115A (https=) |
| MX (2) | MX2021014913A (https=) |
| MY (1) | MY200810A (https=) |
| PE (1) | PE20220134A1 (https=) |
| PH (1) | PH12021553062A1 (https=) |
| SA (1) | SA521431048B1 (https=) |
| SG (1) | SG11202113244UA (https=) |
| UA (1) | UA128540C2 (https=) |
| WO (1) | WO2020247429A1 (https=) |
| ZA (1) | ZA202109251B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023078333A1 (zh) | 2021-11-03 | 2023-05-11 | 上海拓界生物医药科技有限公司 | 一种取代的苯丙酸衍生物及其用途一种取代的苯丙酸衍生物及其用途 |
| WO2023146785A1 (en) | 2022-01-26 | 2023-08-03 | Eli Lilly And Company | Pyrrolidine compounds |
| CN120787221A (zh) | 2023-03-24 | 2025-10-14 | 上海京新生物医药有限公司 | 一种环状胺衍生物及其组合物与应用 |
| CN119894882A (zh) * | 2023-04-21 | 2025-04-25 | 深圳信立泰药业股份有限公司 | 一种叔胺类化合物及其制备方法和医药用途 |
| WO2024230805A1 (zh) | 2023-05-11 | 2024-11-14 | 江苏恒瑞医药股份有限公司 | 一种脂蛋白化合物晶型及其制备方法 |
| TW202509024A (zh) | 2023-05-19 | 2025-03-01 | 大陸商深圳信立泰藥業股份有限公司 | 一種磺醯胺類化合物及其製備方法和醫藥用途 |
| EP4734986A1 (en) | 2023-06-30 | 2026-05-06 | Eli Lilly and Company | Therapeutic uses and doses of lp(a) disrupter compounds |
| WO2025024216A1 (en) | 2023-07-21 | 2025-01-30 | Eli Lilly And Company | PYRROLIDINE COMPOUNDS Lp(a) LOWERING ACTIVITY |
| WO2025024218A1 (en) | 2023-07-21 | 2025-01-30 | Eli Lilly And Company | PYRROLIDINE COMPOUNDS WITH Lp(a) LOWERING ACTIVITY |
| WO2025024210A1 (en) | 2023-07-21 | 2025-01-30 | Eli Lilly And Company | Piperidine, morpholine and tetrahydro-pyridazine compounds with lp(a) lowering activity |
| CN121548568A (zh) | 2023-07-21 | 2026-02-17 | 伊莱利利公司 | 具有Lp(a)降低活性的哌啶化合物 |
| CN119490445A (zh) * | 2023-08-15 | 2025-02-21 | 深圳信立泰药业股份有限公司 | 一种酰基类化合物及其制备方法和医药用途 |
| US20250179055A1 (en) * | 2023-11-17 | 2025-06-05 | Innovstone Therapeutics Limited | Substituted 2-(pyrrolidine-3-yl)acetic acid derivative, preparation method and use thereof |
| WO2025108255A1 (zh) * | 2023-11-20 | 2025-05-30 | 上海齐鲁制药研究中心有限公司 | 一种多环类衍生物、其制备方法和应用 |
| WO2025237188A1 (zh) * | 2024-05-14 | 2025-11-20 | 石家庄以岭药业股份有限公司 | 一种LP(a)抑制剂化合物及其应用 |
| WO2025255324A1 (en) * | 2024-06-06 | 2025-12-11 | Lapis Therapeutics, Inc. | Inhibitors of lipoprotein(a) assembly |
| WO2026061518A1 (zh) * | 2024-09-23 | 2026-03-26 | 上海京新生物医药有限公司 | 一种环状胺衍生物的固体形式、制备方法及药物组合物 |
| JP7850336B1 (ja) | 2024-11-14 | 2026-04-22 | イーライ リリー アンド カンパニー | Ｌｐ（ａ）阻害剤化合物を含む経口組成物 |
| CN121609698A (zh) * | 2026-01-30 | 2026-03-06 | 山东京新药业有限公司 | 一种莫伐培林及中间体的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2685325B1 (fr) * | 1991-12-20 | 1994-02-04 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US7371777B2 (en) | 2001-08-17 | 2008-05-13 | Eisai Co., Ltd. | Cyclic compound and PPAR agonist |
| AU2003300438A1 (en) * | 2003-12-24 | 2005-08-03 | Esperion Therapeutics, Inc. | Ether compounds and compositions for cholesterol management and related uses |
| JP2007525408A (ja) * | 2003-12-24 | 2007-09-06 | エスペリオン セラピューティクス，インコーポレイテッド | コレステロール管理および関連使用のためのケトン化合物および組成物 |
| CA2694362A1 (en) | 2007-07-27 | 2009-02-05 | F. Hoffmann-La Roche Ag | 2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as taar-ligands |
| KR20180086259A (ko) | 2016-02-03 | 2018-07-30 | 상하이 하이옌 파마슈티컬 테크놀로지 컴퍼니, 리미티드 | 헤테로 고리로 치환된 n-설포닐벤즈아미드 유도체, 이의 제조 방법과 약학적 용도 |
| CN112321475B (zh) | 2020-11-13 | 2022-06-10 | 四川大学 | 一种γ-氨基酸类似物及其合成方法 |
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2020
- 2020-06-03 US US17/056,144 patent/US11286249B2/en active Active
- 2020-06-03 PH PH1/2021/553062A patent/PH12021553062A1/en unknown
- 2020-06-03 SG SG11202113244UA patent/SG11202113244UA/en unknown
- 2020-06-03 PE PE2021002037A patent/PE20220134A1/es unknown
- 2020-06-03 KR KR1020227043106A patent/KR102629923B1/ko active Active
- 2020-06-03 WO PCT/US2020/035825 patent/WO2020247429A1/en not_active Ceased
- 2020-06-03 CR CR20210602A patent/CR20210602A/es unknown
- 2020-06-03 UA UAA202106553A patent/UA128540C2/uk unknown
- 2020-06-03 BR BR112021023347A patent/BR112021023347A2/pt unknown
- 2020-06-03 IL IL288174A patent/IL288174B2/en unknown
- 2020-06-03 IL IL321703A patent/IL321703B1/en unknown
- 2020-06-03 KR KR1020247002433A patent/KR102720992B1/ko active Active
- 2020-06-03 MA MA056115A patent/MA56115A/fr unknown
- 2020-06-03 JP JP2021505713A patent/JP6940717B2/ja active Active
- 2020-06-03 EA EA202193007A patent/EA202193007A1/ru unknown
- 2020-06-03 EP EP20747210.1A patent/EP3980409A1/en active Pending
- 2020-06-03 CN CN202080041924.XA patent/CN114008021B/zh active Active
- 2020-06-03 AU AU2020287599A patent/AU2020287599B2/en active Active
- 2020-06-03 MY MYPI2021007256A patent/MY200810A/en unknown
- 2020-06-03 MX MX2021014913A patent/MX2021014913A/es unknown
- 2020-06-03 KR KR1020217040065A patent/KR102477481B1/ko active Active
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2021
- 2021-09-02 JP JP2021143227A patent/JP7508422B2/ja active Active
- 2021-11-18 ZA ZA2021/09251A patent/ZA202109251B/en unknown
- 2021-11-30 CO CONC2021/0016295A patent/CO2021016295A2/es unknown
- 2021-12-01 JO JOJO/P/2021/0319A patent/JOP20210319B1/ar active
- 2021-12-01 CL CL2021003202A patent/CL2021003202A1/es unknown
- 2021-12-03 MX MX2025001789A patent/MX2025001789A/es unknown
- 2021-12-07 EC ECSENADI202188515A patent/ECSP21088515A/es unknown
- 2021-12-07 DO DO2021000254A patent/DOP2021000254A/es unknown
- 2021-12-07 SA SA521431048A patent/SA521431048B1/ar unknown
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2022
- 2022-02-15 US US17/671,806 patent/US12441714B2/en active Active
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2024
- 2024-06-18 JP JP2024098153A patent/JP7658014B2/ja active Active
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2025
- 2025-03-26 JP JP2025052039A patent/JP2025098178A/ja active Pending
- 2025-07-11 US US19/267,125 patent/US20260055086A1/en active Pending