CL2021003202A1 - Compuestos de pirrolidina - Google Patents
Compuestos de pirrolidinaInfo
- Publication number
- CL2021003202A1 CL2021003202A1 CL2021003202A CL2021003202A CL2021003202A1 CL 2021003202 A1 CL2021003202 A1 CL 2021003202A1 CL 2021003202 A CL2021003202 A CL 2021003202A CL 2021003202 A CL2021003202 A CL 2021003202A CL 2021003202 A1 CL2021003202 A1 CL 2021003202A1
- Authority
- CL
- Chile
- Prior art keywords
- formula
- compounds
- pyrrolidine compounds
- nhso2nh
- ch2nhch2
- Prior art date
Links
- 150000003235 pyrrolidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Abstract
La presente invención proporciona compuestos de la Fórmula (I) en donde L se selecciona del grupo que consiste en -CH2NHCH2-, - CH2NH-, -NH-, -S-, -S(O)-, -S(O)2-, -O-, -OCH2-, -OCH2CH2O-, - NHSO2NH- (II), y (III) o una sal farmacéuticamente aceptable de estos; un compuesto de la fórmula (IV), procesos para preparar los compuestos y sus sales, una composición farmacéutica y métodos para tratar pacientes que necesiten dicho tratamiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19382477 | 2019-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2021003202A1 true CL2021003202A1 (es) | 2022-09-09 |
Family
ID=66821161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2021003202A CL2021003202A1 (es) | 2019-06-07 | 2021-12-01 | Compuestos de pirrolidina |
Country Status (22)
Country | Link |
---|---|
US (2) | US11286249B2 (es) |
EP (1) | EP3980409A1 (es) |
JP (2) | JP6940717B2 (es) |
KR (3) | KR102629923B1 (es) |
CN (1) | CN114008021A (es) |
AU (1) | AU2020287599B2 (es) |
BR (1) | BR112021023347A2 (es) |
CA (1) | CA3140869A1 (es) |
CL (1) | CL2021003202A1 (es) |
CO (1) | CO2021016295A2 (es) |
CR (1) | CR20210602A (es) |
DO (1) | DOP2021000254A (es) |
EA (1) | EA202193007A1 (es) |
EC (1) | ECSP21088515A (es) |
IL (1) | IL288174A (es) |
JO (1) | JOP20210319A1 (es) |
MA (1) | MA56115A (es) |
MX (1) | MX2021014913A (es) |
PE (1) | PE20220134A1 (es) |
SG (1) | SG11202113244UA (es) |
WO (1) | WO2020247429A1 (es) |
ZA (1) | ZA202109251B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2022381258A1 (en) | 2021-11-03 | 2024-05-02 | Tuojie Biotech (Shanghai) Co., Ltd. | Substituted phenylpropionic acid derivative and use thereof |
WO2023146785A1 (en) | 2022-01-26 | 2023-08-03 | Eli Lilly And Company | Pyrrolidine compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003016265A1 (fr) * | 2001-08-17 | 2003-02-27 | Eisai Co., Ltd. | Compose cyclique et agoniste du recepteur ppar |
AU2003300438A1 (en) | 2003-12-24 | 2005-08-03 | Esperion Therapeutics, Inc. | Ether compounds and compositions for cholesterol management and related uses |
US7705177B2 (en) | 2003-12-24 | 2010-04-27 | Esperion Therapuetics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
-
2020
- 2020-06-03 SG SG11202113244UA patent/SG11202113244UA/en unknown
- 2020-06-03 BR BR112021023347A patent/BR112021023347A2/pt unknown
- 2020-06-03 JP JP2021505713A patent/JP6940717B2/ja active Active
- 2020-06-03 WO PCT/US2020/035825 patent/WO2020247429A1/en active Application Filing
- 2020-06-03 AU AU2020287599A patent/AU2020287599B2/en active Active
- 2020-06-03 MX MX2021014913A patent/MX2021014913A/es unknown
- 2020-06-03 US US17/056,144 patent/US11286249B2/en active Active
- 2020-06-03 CA CA3140869A patent/CA3140869A1/en active Pending
- 2020-06-03 JO JOP/2021/0319A patent/JOP20210319A1/ar unknown
- 2020-06-03 EA EA202193007A patent/EA202193007A1/ru unknown
- 2020-06-03 MA MA056115A patent/MA56115A/fr unknown
- 2020-06-03 CN CN202080041924.XA patent/CN114008021A/zh active Pending
- 2020-06-03 CR CR20210602A patent/CR20210602A/es unknown
- 2020-06-03 KR KR1020227043106A patent/KR102629923B1/ko active IP Right Grant
- 2020-06-03 PE PE2021002037A patent/PE20220134A1/es unknown
- 2020-06-03 KR KR1020217040065A patent/KR102477481B1/ko active IP Right Grant
- 2020-06-03 EP EP20747210.1A patent/EP3980409A1/en active Pending
- 2020-06-03 KR KR1020247002433A patent/KR20240014618A/ko active Application Filing
-
2021
- 2021-09-02 JP JP2021143227A patent/JP2021191784A/ja active Pending
- 2021-11-16 IL IL288174A patent/IL288174A/en unknown
- 2021-11-18 ZA ZA2021/09251A patent/ZA202109251B/en unknown
- 2021-11-30 CO CONC2021/0016295A patent/CO2021016295A2/es unknown
- 2021-12-01 CL CL2021003202A patent/CL2021003202A1/es unknown
- 2021-12-07 DO DO2021000254A patent/DOP2021000254A/es unknown
- 2021-12-07 EC ECSENADI202188515A patent/ECSP21088515A/es unknown
-
2022
- 2022-02-15 US US17/671,806 patent/US20220169636A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6940717B2 (ja) | 2021-09-29 |
AU2020287599A1 (en) | 2022-01-06 |
IL288174A (en) | 2022-01-01 |
EA202193007A1 (ru) | 2022-03-25 |
KR102477481B1 (ko) | 2022-12-15 |
US20210253559A1 (en) | 2021-08-19 |
CO2021016295A2 (es) | 2021-12-10 |
CR20210602A (es) | 2022-01-06 |
JOP20210319A1 (ar) | 2023-01-30 |
MX2021014913A (es) | 2022-01-18 |
WO2020247429A1 (en) | 2020-12-10 |
SG11202113244UA (en) | 2021-12-30 |
ZA202109251B (en) | 2024-04-24 |
KR20240014618A (ko) | 2024-02-01 |
DOP2021000254A (es) | 2022-01-16 |
BR112021023347A2 (pt) | 2022-04-12 |
KR20230004890A (ko) | 2023-01-06 |
KR20220018494A (ko) | 2022-02-15 |
EP3980409A1 (en) | 2022-04-13 |
ECSP21088515A (es) | 2022-01-31 |
US11286249B2 (en) | 2022-03-29 |
CA3140869A1 (en) | 2020-12-10 |
KR102629923B1 (ko) | 2024-01-30 |
JP2021524498A (ja) | 2021-09-13 |
CN114008021A (zh) | 2022-02-01 |
AU2020287599B2 (en) | 2023-10-19 |
JP2021191784A (ja) | 2021-12-16 |
US20220169636A1 (en) | 2022-06-02 |
MA56115A (fr) | 2022-04-13 |
PE20220134A1 (es) | 2022-01-27 |
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