JP2023512828A5 - - Google Patents

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Publication number
JP2023512828A5
JP2023512828A5 JP2022548125A JP2022548125A JP2023512828A5 JP 2023512828 A5 JP2023512828 A5 JP 2023512828A5 JP 2022548125 A JP2022548125 A JP 2022548125A JP 2022548125 A JP2022548125 A JP 2022548125A JP 2023512828 A5 JP2023512828 A5 JP 2023512828A5
Authority
JP
Japan
Prior art keywords
formula
pharmaceutical composition
pharmaceutically acceptable
composition according
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022548125A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023512828A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/016920 external-priority patent/WO2021158992A1/en
Publication of JP2023512828A publication Critical patent/JP2023512828A/ja
Publication of JP2023512828A5 publication Critical patent/JP2023512828A5/ja
Pending legal-status Critical Current

Links

JP2022548125A 2020-02-07 2021-02-05 クロマカリムプロドラッグ療法のための改善された方法及び組成物 Pending JP2023512828A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062971752P 2020-02-07 2020-02-07
US62/971,752 2020-02-07
US202063120604P 2020-12-02 2020-12-02
US63/120,604 2020-12-02
US202163134042P 2021-01-05 2021-01-05
US63/134,042 2021-01-05
PCT/US2021/016920 WO2021158992A1 (en) 2020-02-07 2021-02-05 Improved methods and compositions for cromakalim prodrug therapy

Publications (2)

Publication Number Publication Date
JP2023512828A JP2023512828A (ja) 2023-03-29
JP2023512828A5 true JP2023512828A5 (https=) 2024-02-14

Family

ID=77199473

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548125A Pending JP2023512828A (ja) 2020-02-07 2021-02-05 クロマカリムプロドラッグ療法のための改善された方法及び組成物

Country Status (7)

Country Link
US (1) US20220387457A1 (https=)
EP (1) EP4100003A4 (https=)
JP (1) JP2023512828A (https=)
CN (1) CN115768419A (https=)
AU (1) AU2021215932A1 (https=)
CA (1) CA3166579A1 (https=)
WO (1) WO2021158992A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10981951B2 (en) * 2014-01-31 2021-04-20 Mayo Foundation For Medical Education And Research Therapeutics for the treatment of glaucoma
CA3159771A1 (en) 2019-12-12 2021-06-17 Thurein M. Htoo Controlled-delivery cromakalim prodrugs
EP4384162A4 (en) * 2021-08-12 2025-06-04 Qlaris Bio, Inc. Compositions and methods for extended-release bromo-kallim therapy
CN115058440B (zh) * 2022-06-08 2023-08-15 郑州轻工业大学 催化合成天然蔗糖酯的工程菌及其构建方法和应用
GB202211936D0 (en) * 2022-08-16 2022-09-28 Royal Veterinary College Method and treatment for diabetes
IL320428A (en) * 2022-11-04 2025-06-01 Qlaris Bio Inc Topical ophthalmic administration of cromolyns
CN119548509B (zh) * 2024-11-21 2025-11-14 中山大学中山眼科中心 一种小分子化合物组合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
WO1989010757A1 (en) * 1988-05-10 1989-11-16 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis New ophthalmic preparation for treating glaucoma
US5565560A (en) * 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
CN101327325A (zh) * 2002-07-30 2008-12-24 奥默罗斯公司 眼科冲洗液及方法
DK2838533T3 (da) * 2012-04-16 2017-11-27 Univ Case Western Reserve Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet
US10981951B2 (en) * 2014-01-31 2021-04-20 Mayo Foundation For Medical Education And Research Therapeutics for the treatment of glaucoma
MA41252A (fr) * 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
WO2018047175A1 (en) * 2016-09-08 2018-03-15 Regenera Pharma Ltd. Compositions comprising triterpenoids and uses thereof for treating optic neuropathy
CA3159771A1 (en) * 2019-12-12 2021-06-17 Thurein M. Htoo Controlled-delivery cromakalim prodrugs

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