JP2022533966A5 - - Google Patents

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Publication number
JP2022533966A5
JP2022533966A5 JP2021568390A JP2021568390A JP2022533966A5 JP 2022533966 A5 JP2022533966 A5 JP 2022533966A5 JP 2021568390 A JP2021568390 A JP 2021568390A JP 2021568390 A JP2021568390 A JP 2021568390A JP 2022533966 A5 JP2022533966 A5 JP 2022533966A5
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JP
Japan
Prior art keywords
aptamer
pharmaceutical composition
composition according
approximately
minutes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021568390A
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English (en)
Japanese (ja)
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JP7789563B2 (ja
JP2022533966A (ja
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Priority claimed from PCT/IB2020/054655 external-priority patent/WO2020230109A1/en
Publication of JP2022533966A publication Critical patent/JP2022533966A/ja
Publication of JP2022533966A5 publication Critical patent/JP2022533966A5/ja
Priority to JP2025117499A priority Critical patent/JP2025148491A/ja
Application granted granted Critical
Publication of JP7789563B2 publication Critical patent/JP7789563B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021568390A 2019-05-16 2020-05-16 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療 Active JP7789563B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025117499A JP2025148491A (ja) 2019-05-16 2025-07-11 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962849068P 2019-05-16 2019-05-16
US201962849072P 2019-05-16 2019-05-16
US62/849,068 2019-05-16
US62/849,072 2019-05-16
EP19382425 2019-05-27
EP19382424 2019-05-27
EP19382425 2019-05-27
EP19382424 2019-05-27
PCT/IB2020/054655 WO2020230109A1 (en) 2019-05-16 2020-05-16 Treatment of tlr-4 mediated diseases and conditions with aptamers targeting tlr-4

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025117499A Division JP2025148491A (ja) 2019-05-16 2025-07-11 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療

Publications (3)

Publication Number Publication Date
JP2022533966A JP2022533966A (ja) 2022-07-27
JP2022533966A5 true JP2022533966A5 (https=) 2023-05-25
JP7789563B2 JP7789563B2 (ja) 2025-12-22

Family

ID=73288968

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021568390A Active JP7789563B2 (ja) 2019-05-16 2020-05-16 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療
JP2025117499A Pending JP2025148491A (ja) 2019-05-16 2025-07-11 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025117499A Pending JP2025148491A (ja) 2019-05-16 2025-07-11 Tlr-4を標的とするアプタマーによるtlr-4媒介性の疾患および状態の治療

Country Status (7)

Country Link
US (2) US20220233572A1 (https=)
EP (1) EP3969011A1 (https=)
JP (2) JP7789563B2 (https=)
CN (1) CN113966220A (https=)
AU (1) AU2020276703A1 (https=)
CA (2) CA3140285A1 (https=)
WO (2) WO2020230109A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12390172B2 (en) * 2021-02-19 2025-08-19 Canon Medical Systems Corporation Method and apparatus for displaying medical images
WO2024064288A1 (en) * 2022-09-22 2024-03-28 Thomas Jefferson University Tlr4 inhibitors for cancer treatment
IL321911A (en) 2023-01-05 2025-09-01 Merck Patent Gmbh Aptol molecules for the treatment of ischemic stroke and intracranial hemorrhages
AU2024275027A1 (en) 2023-05-22 2025-12-11 Merck Patent Gmbh New tlr-4 antagonist aptamers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
JPH088933B2 (ja) * 1987-07-10 1996-01-31 日本ゼオン株式会社 カテ−テル
SG10201406016SA (en) 2006-04-03 2014-11-27 Stella Aps Pharmaceutical composition comprising anti-mirna antisense oligonucleotides
DK2149605T3 (da) 2007-03-22 2013-09-30 Santaris Pharma As Korte RNA antagonist forbindelser til modulering af det ønskede mRNA
ES2599979T3 (es) 2009-04-24 2017-02-06 Roche Innovation Center Copenhagen A/S Composiciones farmacéuticas para el tratamiento de pacientes de VHC que no responden al interferón
EP2619189B1 (en) 2010-09-24 2020-04-15 Zoetis Services LLC Isoxazoline oximes as antiparasitic agents
ES2555160B1 (es) 2014-06-24 2016-10-25 Aptus Biotech, S.L. Aptámeros específicos de TLR-4 y usos de los mismos
WO2020069313A2 (en) * 2018-09-28 2020-04-02 Henry Ford Health System Use of extracellular vesicles in combination with tissue plasminogen activator and/or thrombectomy to treat stroke

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