JP2023144018A5 - - Google Patents
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- JP2023144018A5 JP2023144018A5 JP2023129665A JP2023129665A JP2023144018A5 JP 2023144018 A5 JP2023144018 A5 JP 2023144018A5 JP 2023129665 A JP2023129665 A JP 2023129665A JP 2023129665 A JP2023129665 A JP 2023129665A JP 2023144018 A5 JP2023144018 A5 JP 2023144018A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acids
- modified
- substituted
- region
- costimulatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562241021P | 2015-10-13 | 2015-10-13 | |
| US62/241,021 | 2015-10-13 | ||
| JP2018519030A JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| PCT/US2016/056901 WO2017066481A1 (en) | 2015-10-13 | 2016-10-13 | Chimeric antigen receptors containing a chlorotoxin domain |
| JP2022007016A JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022007016A Division JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023144018A JP2023144018A (ja) | 2023-10-06 |
| JP2023144018A5 true JP2023144018A5 (https=) | 2024-02-21 |
| JP7674425B2 JP7674425B2 (ja) | 2025-05-09 |
Family
ID=57233854
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519030A Active JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| JP2022007016A Active JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
| JP2023129665A Active JP7674425B2 (ja) | 2015-10-13 | 2023-08-09 | クロロトキシン領域を含むキメラ抗原受容体 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519030A Active JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| JP2022007016A Active JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11230577B2 (https=) |
| EP (2) | EP3985027A1 (https=) |
| JP (3) | JP7085990B2 (https=) |
| KR (1) | KR102930014B1 (https=) |
| CN (1) | CN108368159A (https=) |
| CA (1) | CA3001833A1 (https=) |
| DK (1) | DK3362470T3 (https=) |
| ES (1) | ES2902987T3 (https=) |
| IL (2) | IL302560B2 (https=) |
| PL (1) | PL3362470T3 (https=) |
| PT (1) | PT3362470T (https=) |
| WO (1) | WO2017066481A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2879700T3 (es) | 2016-02-05 | 2021-11-22 | Hope City | Administración de células T genomanipuladas para el tratamiento de cánceres en el sistema nervioso central |
| KR20240005168A (ko) | 2016-11-04 | 2024-01-11 | 2세븐티 바이오, 인코포레이티드 | 항-bcma car t 세포 조성물 |
| CN110352068A (zh) | 2016-12-02 | 2019-10-18 | 南加利福尼亚大学 | 合成的免疫受体及其使用方法 |
| KR102618373B1 (ko) | 2016-12-09 | 2023-12-29 | 유에이비 리서치 파운데이션 | 키메라성 클로로톡신 수용체 |
| WO2019084018A1 (en) * | 2017-10-23 | 2019-05-02 | City Of Hope | CAR FOR THE TREATMENT OF HIV INFECTION |
| JP2020108444A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108442A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020103676A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020103675A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020103674A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020108446A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108441A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108445A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020103673A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020103677A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020108443A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP7584437B2 (ja) * | 2019-04-05 | 2024-11-15 | ２セブンティ バイオ インコーポレイテッド | 抗ｂｃｍａ ｃａｒ ｔ細胞の製造 |
| CN114051532A (zh) * | 2019-05-24 | 2022-02-15 | 希望之城公司 | 用于治疗ccr4阳性恶性肿瘤的经ccr4靶向性嵌合抗原受体修饰的t细胞 |
| US20230374085A1 (en) * | 2020-03-11 | 2023-11-23 | City Of Hope | Dual-targeting chimeric antigen receptor modified t cells comprising il-13 and chlorotoxin for cancer treatment |
| EP4271702B1 (en) | 2020-12-30 | 2024-11-06 | VRG Therapeutics Zrt. | Chlorotoxin derivatives and use thereof |
| JP2024503507A (ja) * | 2021-01-20 | 2024-01-25 | インエイトバイオ，インコーポレイテッド | 多価クロロトキシンキメラ抗原受容体 |
| WO2022212525A2 (en) | 2021-03-30 | 2022-10-06 | City Of Hope | Car t cell therapy and ifn gamma |
| US20230190799A1 (en) * | 2021-07-21 | 2023-06-22 | City Of Hope | Chimeric antigen receptor t cells targeting cea and anti-cea-il2 immunocytokines for cancer therapy |
| WO2023092733A1 (zh) * | 2021-11-25 | 2023-06-01 | 苏州慧疗生物医药科技有限公司 | 一种用于有效递送核酸的环状多肽载体及其变化形式 |
| CN114014941B (zh) * | 2022-01-10 | 2022-04-12 | 卡瑞济(北京)生命科技有限公司 | 靶向IL13Rα2的嵌合抗原受体及其用途 |
| JP2025508371A (ja) * | 2022-02-11 | 2025-03-26 | フレッド ハッチンソン キャンサー センター | Ｓｔｅａｐ１に結合するキメラ抗原受容体 |
| AU2023290273A1 (en) * | 2022-06-14 | 2024-12-12 | Purdue Research Foundation | Car-expressing pluripotent stem cell-derived neutrophils loaded with drug nanoparticles and uses thereof |
| WO2025235801A1 (en) | 2024-05-08 | 2025-11-13 | City Of Hope | Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005019728D1 (de) * | 2004-04-06 | 2010-04-15 | Transmolecular Inc | Diagnose und behandlung von myeloid- und lymphoidzellenkrebs mit chlorotoxin oder derivat |
| CN100564517C (zh) * | 2006-09-21 | 2009-12-02 | 武汉大学 | 一种蝎抗神经胶质瘤肽及其制备方法和应用 |
| EP4032552B1 (en) * | 2008-08-26 | 2023-10-04 | City of Hope | Method and compositions for enhanced anti-tumor effector functioning of t cells |
| EP3444333A1 (en) * | 2009-10-22 | 2019-02-20 | Thomas Jefferson University | Cell-based anti-cancer compositions and methods of making and using the same |
| JP5858932B2 (ja) * | 2010-02-04 | 2016-02-10 | モルフォテック， インコーポレイテッド | クロロトキシンポリペプチドおよびコンジュゲートならびにその使用 |
| US9359447B2 (en) * | 2012-03-23 | 2016-06-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-mesothelin chimeric antigen receptors |
| CN105008393A (zh) * | 2012-12-10 | 2015-10-28 | 弗莱德哈钦森癌症研究中心 | 用于筛选的方法 |
| UY35468A (es) * | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| US10144770B2 (en) * | 2013-10-17 | 2018-12-04 | National University Of Singapore | Chimeric receptors and uses thereof in immune therapy |
| US20160333108A1 (en) | 2014-01-13 | 2016-11-17 | Stephen J. Forman | CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE |
| AU2016246457B2 (en) * | 2015-04-06 | 2020-10-15 | Cytoimmune Therapeutics, Inc. | EGFR-directed car therapy for glioblastoma |
| KR101888387B1 (ko) * | 2015-05-29 | 2018-08-20 | 코닌클리케 필립스 엔.브이. | 리브들을 포함하는 밀봉 개스킷을 갖는 블렌더 |
-
2016
- 2016-10-13 CA CA3001833A patent/CA3001833A1/en active Pending
- 2016-10-13 US US15/767,960 patent/US11230577B2/en active Active
- 2016-10-13 IL IL302560A patent/IL302560B2/en unknown
- 2016-10-13 EP EP21197997.6A patent/EP3985027A1/en active Pending
- 2016-10-13 EP EP16791158.5A patent/EP3362470B1/en active Active
- 2016-10-13 WO PCT/US2016/056901 patent/WO2017066481A1/en not_active Ceased
- 2016-10-13 DK DK16791158.5T patent/DK3362470T3/da active
- 2016-10-13 KR KR1020187013153A patent/KR102930014B1/ko active Active
- 2016-10-13 JP JP2018519030A patent/JP7085990B2/ja active Active
- 2016-10-13 CN CN201680072823.2A patent/CN108368159A/zh active Pending
- 2016-10-13 IL IL258670A patent/IL258670B2/en unknown
- 2016-10-13 ES ES16791158T patent/ES2902987T3/es active Active
- 2016-10-13 PL PL16791158T patent/PL3362470T3/pl unknown
- 2016-10-13 PT PT167911585T patent/PT3362470T/pt unknown
-
2021
- 2021-11-05 US US17/520,402 patent/US20220177528A1/en active Pending
-
2022
- 2022-01-20 JP JP2022007016A patent/JP7331162B2/ja active Active
-
2023
- 2023-08-09 JP JP2023129665A patent/JP7674425B2/ja active Active
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