JP2023109992A5 - - Google Patents
Info
- Publication number
- JP2023109992A5 JP2023109992A5 JP2023089121A JP2023089121A JP2023109992A5 JP 2023109992 A5 JP2023109992 A5 JP 2023109992A5 JP 2023089121 A JP2023089121 A JP 2023089121A JP 2023089121 A JP2023089121 A JP 2023089121A JP 2023109992 A5 JP2023109992 A5 JP 2023109992A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- nucleotide sequence
- composition
- nucleic acid
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17172818 | 2017-05-24 | ||
| ES201700615 | 2017-05-24 | ||
| ES201700615 | 2017-05-24 | ||
| EP17172818.1 | 2017-05-24 | ||
| JP2019565341A JP7778469B2 (ja) | 2017-05-24 | 2018-05-24 | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
| PCT/EP2018/063707 WO2018215613A1 (en) | 2017-05-24 | 2018-05-24 | Viral expression construct comprising a fibroblast growth factor 21 (fgf21) coding sequence |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565341A Division JP7778469B2 (ja) | 2017-05-24 | 2018-05-24 | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023109992A JP2023109992A (ja) | 2023-08-08 |
| JP2023109992A5 true JP2023109992A5 (https=) | 2025-08-26 |
Family
ID=62620819
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565341A Active JP7778469B2 (ja) | 2017-05-24 | 2018-05-24 | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
| JP2023089121A Pending JP2023109992A (ja) | 2017-05-24 | 2023-05-30 | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565341A Active JP7778469B2 (ja) | 2017-05-24 | 2018-05-24 | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200102361A1 (https=) |
| EP (1) | EP3630160A1 (https=) |
| JP (2) | JP7778469B2 (https=) |
| CN (1) | CN110913886A (https=) |
| AU (2) | AU2018274655B2 (https=) |
| BR (1) | BR112019024608A2 (https=) |
| MX (1) | MX2019013982A (https=) |
| WO (1) | WO2018215613A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3630160A1 (en) * | 2017-05-24 | 2020-04-08 | Universitat Autònoma De Barcelona | Viral expression construct comprising a fibroblast growth factor 21 (fgf21) coding sequence |
| IL270882B2 (en) | 2017-05-24 | 2024-02-01 | Univ Barcelona Autonoma | Viral expression vectors containing the coding sequence for FIBROBLAST GROWTH FACTOR 21 (FGF21 |
| GB201818816D0 (en) * | 2018-11-19 | 2019-01-02 | Synpromics Ltd | Regulatory nucleic acid sequences |
| CA3120923A1 (en) * | 2018-11-26 | 2020-06-04 | Universitat Autonoma De Barcelona | Fibroblast growth factor 21 (fgf21) gene therapy |
| ES2948620T3 (es) | 2019-07-10 | 2023-09-14 | Masonic Medical Res Laboratory | Vgll4 con elemento regulador CIS de UCP-1 y método de uso del mismo |
| US12611436B2 (en) | 2019-10-17 | 2026-04-28 | Sarepta Therapeutics, Inc. | AAV transfer cassette |
| KR20230017845A (ko) * | 2020-05-26 | 2023-02-06 | 유니버시타트 아우토노마 데 바르셀로나 | 중추 신경계 장애에 대한 섬유아세포 성장 인자 21(fgf21) 유전자 요법 |
| CN113956344A (zh) * | 2021-10-14 | 2022-01-21 | 江南大学 | 一种新型治疗肝癌的fgf类似物及其应用 |
| CN114010666B (zh) * | 2021-10-22 | 2024-05-07 | 上海交通大学 | 溶瘤病毒、parp抑制剂及pd-1抗体在制备抗肿瘤药物中的应用 |
| CN114316018A (zh) * | 2021-11-26 | 2022-04-12 | 江南大学 | 一种fgf21蛋白类似物及其应用 |
| CN118460618A (zh) * | 2022-04-19 | 2024-08-09 | 康霖生物科技（杭州）有限公司 | 一种用于遗传性凝血因子缺乏病治疗的核酸构建体 |
| EP4598590A1 (en) * | 2022-10-08 | 2025-08-13 | Lingyi Biotech Co., Ltd. | Construct for enhancing gene expression |
| WO2025158406A1 (en) * | 2024-01-26 | 2025-07-31 | Source Bio, Inc. | Compositions for adipose tissue targeting and uses thereof |
| CN118389554A (zh) * | 2024-05-10 | 2024-07-26 | 三峡大学 | 一种提高fgf-21持续表达水平和稳定性的aav重组病毒及其应用 |
| WO2026028137A1 (en) * | 2024-07-31 | 2026-02-05 | Universitat Autònoma De Barcelona | Fibroblast growth factor 21 (fgf21) gene therapy |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US5436146A (en) | 1989-09-07 | 1995-07-25 | The Trustees Of Princeton University | Helper-free stocks of recombinant adeno-associated virus vectors |
| US6268213B1 (en) | 1992-06-03 | 2001-07-31 | Richard Jude Samulski | Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy |
| US5869305A (en) | 1992-12-04 | 1999-02-09 | The University Of Pittsburgh | Recombinant viral vector system |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US6204059B1 (en) | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| US6093570A (en) | 1995-06-07 | 2000-07-25 | The University Of North Carolina At Chapel Hill | Helper virus-free AAV production |
| US5741683A (en) | 1995-06-07 | 1998-04-21 | The Research Foundation Of State University Of New York | In vitro packaging of adeno-associated virus DNA |
| US5952221A (en) | 1996-03-06 | 1999-09-14 | Avigen, Inc. | Adeno-associated virus vectors comprising a first and second nucleic acid sequence |
| US6133027A (en) | 1996-08-07 | 2000-10-17 | City Of Hope | Inducible expression system |
| US6548286B1 (en) | 1997-04-14 | 2003-04-15 | Cell Genesys, Inc. | Methods for increasing the efficiency of recombinant AAV product |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| IL132463A0 (en) | 1997-05-13 | 2001-03-19 | Univ North Carolina | Lentivirus - based gene transfer vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US6218181B1 (en) | 1998-03-18 | 2001-04-17 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
| US6146874A (en) | 1998-05-27 | 2000-11-14 | University Of Florida | Method of preparing recombinant adeno-associated virus compositions |
| AU780231B2 (en) | 1998-11-10 | 2005-03-10 | University Of North Carolina At Chapel Hill, The | Virus vectors and methods of making and administering the same |
| DE19909769A1 (de) | 1999-03-05 | 2000-09-07 | Bundesrepublik Deutschland Let | Von SIVagm abgeleitete lentivirale Vektoren, Verfahren zu ihrer Herstellung und ihre Verwendung zur Genübertragung in Säugerzellen |
| US7201898B2 (en) | 2000-06-01 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods and compounds for controlled release of recombinant parvovirus vectors |
| AU2001292881A1 (en) * | 2000-09-20 | 2002-04-02 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| AU2003274397A1 (en) | 2002-06-05 | 2003-12-22 | University Of Florida | Production of pseudotyped recombinant aav virions |
| CN105601748B (zh) * | 2011-07-01 | 2021-08-27 | 恩格姆生物制药公司 | 用于代谢病症和疾病治疗的组合物、应用和方法 |
| MX2014002260A (es) * | 2011-08-31 | 2014-08-18 | Amgen Inc | Factor de crecimiento de fibroblasto 21 para usar en el tratamiento de diabetes tipo 1. |
| EP2692868A1 (en) * | 2012-08-02 | 2014-02-05 | Universitat Autònoma De Barcelona | Adeno-associated viral (AAV) vectors useful for transducing adipose tissue |
| HK1214832A1 (zh) * | 2012-11-28 | 2016-08-05 | 恩格姆生物制药公司 | 用於代謝病症和疾病治療的組合物和方法 |
| US9290557B2 (en) * | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| CN105916990B (zh) * | 2013-08-02 | 2020-02-04 | 巴塞罗那自治大学 | 用于转导脂肪组织的腺相关病毒载体 |
| MX2018014256A (es) * | 2016-05-20 | 2019-08-16 | Harvard College | Metodos de terapia genica para enfermedades y condiciones relacionadas con la edad. |
| EP3630160A1 (en) * | 2017-05-24 | 2020-04-08 | Universitat Autònoma De Barcelona | Viral expression construct comprising a fibroblast growth factor 21 (fgf21) coding sequence |
| CA3120923A1 (en) * | 2018-11-26 | 2020-06-04 | Universitat Autonoma De Barcelona | Fibroblast growth factor 21 (fgf21) gene therapy |
-
2018
- 2018-05-24 EP EP18731359.8A patent/EP3630160A1/en active Pending
- 2018-05-24 WO PCT/EP2018/063707 patent/WO2018215613A1/en not_active Ceased
- 2018-05-24 BR BR112019024608-8A patent/BR112019024608A2/pt unknown
- 2018-05-24 US US16/615,854 patent/US20200102361A1/en not_active Abandoned
- 2018-05-24 AU AU2018274655A patent/AU2018274655B2/en active Active
- 2018-05-24 JP JP2019565341A patent/JP7778469B2/ja active Active
- 2018-05-24 CN CN201880047871.5A patent/CN110913886A/zh active Pending
- 2018-05-24 MX MX2019013982A patent/MX2019013982A/es unknown
-
2023
- 2023-05-30 JP JP2023089121A patent/JP2023109992A/ja active Pending
-
2025
- 2025-04-29 AU AU2025203001A patent/AU2025203001A1/en active Pending
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