JP2023052910A5 - - Google Patents
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- JP2023052910A5 JP2023052910A5 JP2023015725A JP2023015725A JP2023052910A5 JP 2023052910 A5 JP2023052910 A5 JP 2023052910A5 JP 2023015725 A JP2023015725 A JP 2023015725A JP 2023015725 A JP2023015725 A JP 2023015725A JP 2023052910 A5 JP2023052910 A5 JP 2023052910A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025113314A JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017090679 | 2017-04-28 | ||
| JP2017090679 | 2017-04-28 | ||
| PCT/JP2018/017345 WO2018199337A1 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2019514691A JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Division JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113314A Division JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023052910A JP2023052910A (ja) | 2023-04-12 |
| JP2023052910A5 true JP2023052910A5 (https=) | 2023-04-25 |
| JP7708133B2 JP7708133B2 (ja) | 2025-07-15 |
Family
ID=63918939
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Active JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2023015725A Active JP7708133B2 (ja) | 2017-04-28 | 2023-02-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025113314A Active JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A Pending JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Active JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113314A Active JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A Pending JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12024549B2 (https=) |
| EP (2) | EP3617235B1 (https=) |
| JP (4) | JP7222347B2 (https=) |
| KR (3) | KR20240111015A (https=) |
| CN (1) | CN110637036A (https=) |
| AU (2) | AU2018259856B2 (https=) |
| CA (1) | CA3061467A1 (https=) |
| WO (1) | WO2018199337A1 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11472865B2 (en) * | 2017-06-16 | 2022-10-18 | Kagoshima University | IgG-binding peptide, and specific modification of antibody with said peptide |
| CN112261954B (zh) | 2018-06-14 | 2025-06-24 | 味之素株式会社 | 具有针对抗体的亲和性物质和生物正交性官能团的化合物或其盐 |
| CA3103143A1 (en) * | 2018-06-14 | 2019-12-19 | Ajinomoto Co., Inc. | Compound having affinity substance to antibody, cleavable portion, and reactive group, or salt thereof |
| JPWO2020090979A1 (ja) * | 2018-10-31 | 2021-09-24 | 味の素株式会社 | 抗体に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| AU2020210506B2 (en) | 2019-01-23 | 2025-02-13 | AbTis Co., Ltd. | Compound for preparation of antibody-payload conjugate and use thereof |
| JP7393810B2 (ja) | 2019-03-08 | 2023-12-07 | アブティス・カンパニー・リミテッド | 部位特異的抗体コンジュゲーション及びその具体例としての抗体－薬物コンジュゲート |
| WO2021080008A1 (ja) | 2019-10-24 | 2021-04-29 | 国立大学法人 鹿児島大学 | １価ｃｃａｐ生成物の製造方法 |
| JP2023501720A (ja) * | 2019-11-18 | 2023-01-18 | クレオ ファーマシューティカルズ， インコーポレイテッド | 指向性コンジュゲーション技術 |
| IL293375A (en) | 2019-12-03 | 2022-07-01 | Debiopharm Res & Manufacturing S A | reactive couplings |
| WO2022078566A1 (en) | 2020-10-12 | 2022-04-21 | Debiopharm Research & Manufacturing S.A. | Reactive conjugates |
| CA3208296A1 (en) * | 2021-01-18 | 2022-07-21 | Ajinomoto Co., Inc. | Compound or salt thereof, and antibody obtained by using the same |
| EP4279502A4 (en) | 2021-01-18 | 2026-02-11 | Ajinomoto Kk | COMPOUND OR ITS SALT, AND ANTIBODIES THUS OBTAINED |
| EP4306535A1 (en) * | 2021-03-11 | 2024-01-17 | Ajinomoto Co., Inc. | Compound or salt thereof, and antibody obtained using same |
| WO2022196675A1 (ja) | 2021-03-16 | 2022-09-22 | 味の素株式会社 | 複合体またはその塩、およびその製造方法 |
| CN113292633B (zh) * | 2021-05-13 | 2023-08-29 | 中国科学技术大学 | 可见光诱导甘氨酸衍生物的肼化修饰方法 |
| US20240252674A1 (en) * | 2021-05-17 | 2024-08-01 | Biohaven Therapeutics Ltd. | Agents for directed conjugation techniques and conjugated products |
| CA3219550A1 (en) * | 2021-05-19 | 2022-11-24 | Gene M. Dubowchik | Antibody drug conjugates using mates technology for delivering cytotoxic agents |
| AU2022286137A1 (en) | 2021-06-01 | 2023-12-14 | Ajinomoto Co., Inc. | Conjugate of antibody and functional substance or salt of said conjugate, and compound for use in production of said conjugate or salt of said compound |
| US20230201365A1 (en) | 2021-07-09 | 2023-06-29 | Bright Peak Therapeutics Ag | Modified cd20 antibodies and uses thereof |
| US20230201364A1 (en) | 2021-07-09 | 2023-06-29 | Bright Peak Therapeutics Ag | Antibody conjugates and manufacture thereof |
| WO2023281479A1 (en) | 2021-07-09 | 2023-01-12 | Bright Peak Therapeutics Ag | Checkpoint inhibitors conjugated to il-2, and uses thereof |
| WO2023281485A1 (en) | 2021-07-09 | 2023-01-12 | Bright Peak Therapeutics Ag | Modified il-2 polypeptides for treatment of inflammatory and autoimmune diseases |
| US20230181754A1 (en) | 2021-07-09 | 2023-06-15 | Bright Peak Therapeutics Ag | Modified checkpoint inhibitors and uses thereof |
| AU2022342928A1 (en) | 2021-09-08 | 2024-03-28 | Kagoshima University | Compound, salt of compound, antibody modification reagent, method for producing modified antibody, and modified antibody |
| KR20240073035A (ko) | 2021-09-30 | 2024-05-24 | 아지노모토 가부시키가이샤 | 항체 및 기능성 물질의 컨쥬게이트 또는 그 염, 및 그 제조에 사용되는 항체 유도체 및 화합물 또는 그 염 |
| AU2022353331A1 (en) | 2021-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Regioselective conjugate of functional substance and antibody or salt of said conjugate, and antibody derivative and compound for use in production of said conjugate, or salt of said antibody derivative and compound |
| JP2025508823A (ja) | 2022-02-23 | 2025-04-10 | ブライト ピーク セラピューティクス エージー | 免疫抗原特異的ｉｌ－１８免疫サイトカイン及びその使用 |
| EP4488290A1 (en) | 2022-03-04 | 2025-01-08 | ABTIS Co., Ltd. | Method for increasing production yield of antibody-drug conjugate by using thiol-reactive additive |
| CN116836235A (zh) * | 2022-03-25 | 2023-10-03 | 中国科学院上海药物研究所 | 亲和片段导向的可裂解片段，其设计、合成及在制备定点药物偶联物中的应用 |
| WO2023234416A1 (ja) | 2022-06-02 | 2023-12-07 | 味の素株式会社 | 親和性物質、化合物、抗体およびそれらの塩 |
| WO2024096564A1 (ko) | 2022-11-01 | 2024-05-10 | 앱티스 주식회사 | 항-클라우딘18.2 항체를 포함하는 항체-약물 컨쥬게이트 및 이의 암에 대한 치료용도 |
| US20240417436A1 (en) | 2023-01-11 | 2024-12-19 | Bright Peak Therapeutics Ag | Conditionally activated immunocytokines and methods of use |
| US20240424127A1 (en) | 2023-01-11 | 2024-12-26 | Bright Peak Therapeutics Ag | Il-7 polypeptides, immunocytokines comprising same, and uses thereof |
| JPWO2024190896A1 (https=) * | 2023-03-15 | 2024-09-19 | ||
| JPWO2024210154A1 (https=) | 2023-04-04 | 2024-10-10 | ||
| KR20250167673A (ko) | 2023-04-05 | 2025-12-01 | 아지노모토 가부시키가이샤 | 항체 및 기능성 물질의 컨쥬게이트 또는 그 염, 및 티올기를 갖는 항체 중간체 또는 그 염 |
| WO2025041102A1 (en) | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Targeted immune activation with il-18 immunocytokines |
| US20250188166A1 (en) | 2023-08-23 | 2025-06-12 | Bright Peak Therapeutics Ag | Il-18 polypeptides fused to immune cell antigen specific binding polypeptides and uses thereof |
| WO2025041101A1 (en) | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Activatable il-18 immunocytokines and uses thereof |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025076127A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025096878A1 (en) | 2023-11-02 | 2025-05-08 | Capstan Therapeutics, Inc. | Rna for in vivo transfection with increased expression |
| WO2025129201A1 (en) | 2023-12-15 | 2025-06-19 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| WO2025158412A1 (en) | 2024-01-26 | 2025-07-31 | Biohaven Therapeutics Ltd. | BIFUNCTIONAL DEGRADERS OF IgG4 IMMUNOGLOBULINS |
| WO2025179294A2 (en) | 2024-02-22 | 2025-08-28 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025181697A1 (en) | 2024-02-26 | 2025-09-04 | Biohaven Therapeutics Ltd. | Bifunctional degraders of anti-pla2r antibody |
| WO2025210538A1 (en) | 2024-04-02 | 2025-10-09 | Biohaven Therapeutics Ltd. | Bifunctional degraders |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2026028158A1 (en) | 2024-07-31 | 2026-02-05 | Biohaven Therapeutics Ltd. | Targeted degradation of anti-aav antibodies to enable aav-based gene therapy |
| WO2026028159A1 (en) | 2024-07-31 | 2026-02-05 | Biohaven Therapeutics Ltd. | Bifunctional degraders for the treatment of graves' disease |
| KR20260026725A (ko) | 2024-08-20 | 2026-02-27 | 주식회사 엘지에너지솔루션 | 배터리의 전극 탭 검사 장치 및 방법 |
| WO2026058917A1 (ja) * | 2024-09-10 | 2026-03-19 | 味の素株式会社 | 抗体親和性物質を含む化合物、修飾抗体およびそれらの塩ならびに抗体誘導体または抗体－機能性物質コンジュゲートの製造方法 |
| WO2026069134A1 (en) | 2024-09-26 | 2026-04-02 | Bright Peak Therapeutics Ag | Human therapy with il-18 immunocytokines |
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| IL106992A (en) | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| ATE234635T1 (de) | 1995-12-22 | 2003-04-15 | Bristol Myers Squibb Co | Verzweigte hydrazongruppen enthaltende kuppler |
| JP3825502B2 (ja) * | 1996-06-11 | 2006-09-27 | 日本油脂株式会社 | 修飾蛋白質の製造法及びコンタクトレンズ用汚れ除去剤 |
| ES2178854T3 (es) * | 1997-11-07 | 2003-01-01 | Conjuchem Inc | Bibliotecas de marcadores de afinidad para albumina de suero humano. |
| EP2180054A1 (en) | 1999-12-24 | 2010-04-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| EP1757311B1 (en) | 1999-12-24 | 2009-02-11 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| EP1243276A1 (en) | 2001-03-23 | 2002-09-25 | Franciscus Marinus Hendrikus De Groot | Elongated and multiple spacers containing activatible prodrugs |
| DE10162773A1 (de) | 2001-12-20 | 2003-07-10 | Knf Flodos Ag Sursee | Dosierpumpe |
| SI1545613T1 (sl) | 2002-07-31 | 2011-11-30 | Seattle Genetics Inc | Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni |
| JP2006507322A (ja) | 2002-11-14 | 2006-03-02 | シンタルガ・ビーブイ | 多重自己脱離放出スペーサーとして構築されたプロドラッグ |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| JP4806680B2 (ja) | 2004-05-19 | 2011-11-02 | メダレックス インコーポレイテッド | 自己犠牲リンカー及び薬剤複合体 |
| WO2006094269A2 (en) | 2005-03-03 | 2006-09-08 | Covx Technologies Ireland Limited | Anti-angiogenic compounds |
| US8637656B2 (en) | 2005-07-05 | 2014-01-28 | Ribomic Inc. | Nucleic acid capable of binding to immunoglobulin G and use thereof |
| WO2007099289A1 (en) | 2006-02-28 | 2007-09-07 | Medical Research Council | Targeted iron oxide nanoparticles |
| EP2093287A4 (en) | 2006-11-02 | 2010-04-21 | Univ Kagoshima | PEPTIDE BINDER IGG |
| EP2089425B1 (en) | 2006-11-10 | 2011-08-17 | CovX Technologies Ireland Limited | Anti-angiogenic compounds |
| CA2794631A1 (en) * | 2010-03-31 | 2011-10-06 | Universite De Geneve | Stabilized antibody preparations and uses thereof |
| CN103890174B9 (zh) | 2011-08-24 | 2026-04-03 | 大塚化学株式会社 | IgG结合性肽及利用其检测和纯化IgG的方法 |
| WO2014004639A1 (en) | 2012-06-26 | 2014-01-03 | Sutro Biopharma, Inc. | Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use |
| AU2014299561B2 (en) | 2013-06-24 | 2017-06-08 | Ablbio | Antibody-drug conjugate having improved stability and use thereof |
| KR102451080B1 (ko) * | 2014-06-12 | 2022-10-06 | 씨에스피씨 메가리스 바이오파마슈티칼 씨오., 엘티디. | 효소적 방법을 통한 균일한 항체 약물 접합체 |
| US20160000933A1 (en) * | 2014-07-01 | 2016-01-07 | Andrei POLUKHTIN | Conjugated biological molecules and their preparation |
| JP5827769B1 (ja) | 2015-03-27 | 2015-12-02 | 義徳 川窪 | 掃除装置 |
| US10227383B2 (en) * | 2015-05-20 | 2019-03-12 | Kagoshima University | Specific modification of antibody with IgG-binding peptide |
| TWI703158B (zh) * | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| US11135304B2 (en) | 2015-12-18 | 2021-10-05 | Eisai R&D Management Co., Ltd. | C-terminal lysine conjugated immunoglobulins |
| JP7020403B2 (ja) * | 2016-05-02 | 2022-02-16 | 味の素株式会社 | アジド基含有Ｆｃタンパク質 |
| SG10202012408UA (en) * | 2016-06-13 | 2021-01-28 | Univ Kagoshima | SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IgG-BINDING PEPTIDE |
-
2018
- 2018-04-27 EP EP18791007.0A patent/EP3617235B1/en active Active
- 2018-04-27 WO PCT/JP2018/017345 patent/WO2018199337A1/ja not_active Ceased
- 2018-04-27 AU AU2018259856A patent/AU2018259856B2/en active Active
- 2018-04-27 KR KR1020247022678A patent/KR20240111015A/ko active Pending
- 2018-04-27 CN CN201880027775.4A patent/CN110637036A/zh active Pending
- 2018-04-27 KR KR1020197031664A patent/KR20200002858A/ko not_active Ceased
- 2018-04-27 JP JP2019514691A patent/JP7222347B2/ja active Active
- 2018-04-27 KR KR1020247010619A patent/KR20240046307A/ko active Pending
- 2018-04-27 EP EP25168802.4A patent/EP4603507A3/en active Pending
- 2018-04-27 CA CA3061467A patent/CA3061467A1/en active Pending
-
2019
- 2019-10-25 US US16/663,791 patent/US12024549B2/en active Active
-
2023
- 2023-02-03 JP JP2023015725A patent/JP7708133B2/ja active Active
-
2024
- 2024-05-16 US US18/666,145 patent/US20240366783A1/en active Pending
-
2025
- 2025-07-03 JP JP2025113314A patent/JP7754361B2/ja active Active
- 2025-07-22 AU AU2025206404A patent/AU2025206404A1/en active Pending
- 2025-10-02 JP JP2025166056A patent/JP2025185050A/ja active Pending
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