JP2022552158A5 - - Google Patents

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Publication number
JP2022552158A5
JP2022552158A5 JP2022520600A JP2022520600A JP2022552158A5 JP 2022552158 A5 JP2022552158 A5 JP 2022552158A5 JP 2022520600 A JP2022520600 A JP 2022520600A JP 2022520600 A JP2022520600 A JP 2022520600A JP 2022552158 A5 JP2022552158 A5 JP 2022552158A5
Authority
JP
Japan
Prior art keywords
indazole
carboxamide
methyl
alkyl
carbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022520600A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022552158A (ja
JP7600228B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/053882 external-priority patent/WO2021067654A1/en
Publication of JP2022552158A publication Critical patent/JP2022552158A/ja
Publication of JP2022552158A5 publication Critical patent/JP2022552158A5/ja
Application granted granted Critical
Publication of JP7600228B2 publication Critical patent/JP7600228B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022520600A 2019-10-03 2020-10-02 キナーゼ阻害剤としてのインダゾールカルボキサミド Active JP7600228B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962909920P 2019-10-03 2019-10-03
US62/909,920 2019-10-03
PCT/US2020/053882 WO2021067654A1 (en) 2019-10-03 2020-10-02 Indazole carboxamides as kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2022552158A JP2022552158A (ja) 2022-12-15
JP2022552158A5 true JP2022552158A5 (https=) 2023-09-06
JP7600228B2 JP7600228B2 (ja) 2024-12-16

Family

ID=73014622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022520600A Active JP7600228B2 (ja) 2019-10-03 2020-10-02 キナーゼ阻害剤としてのインダゾールカルボキサミド

Country Status (11)

Country Link
US (1) US12275721B2 (https=)
EP (1) EP4037772B1 (https=)
JP (1) JP7600228B2 (https=)
KR (1) KR20220079593A (https=)
CN (1) CN115087651B (https=)
AU (1) AU2020357986A1 (https=)
CA (1) CA3153083A1 (https=)
ES (1) ES2969756T3 (https=)
IL (1) IL291828A (https=)
MX (1) MX2022003769A (https=)
WO (1) WO2021067654A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3849968B1 (en) 2018-09-13 2022-12-21 Bristol-Myers Squibb Company 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1)
EP3849969B1 (en) 2018-09-13 2023-04-19 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors
AR123793A1 (es) 2020-10-19 2023-01-11 Bristol Myers Squibb Co Compuestos de triazolopiridinilo como inhibidores de quinasas
CN114989079B (zh) * 2022-06-21 2023-06-23 中国药科大学 Ripk1激酶靶点抑制剂及其医药用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2004000234A1 (es) * 2003-02-12 2005-04-15 Biogen Idec Inc Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
KR101061599B1 (ko) 2008-12-05 2011-09-02 한국과학기술연구원 비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물
US20110237633A1 (en) 2008-12-11 2011-09-29 Bijoy Panicker Small molecule modulators of hepatocyte growth factor (scatter factor) activity
US9315491B2 (en) 2009-12-28 2016-04-19 Development Center For Biotechnology Pyrimidine compounds as mTOR and PI3K inhibitors
US8987275B2 (en) 2010-03-16 2015-03-24 Dana-Farber Cancer Institute, Inc. Indazole compounds and their uses
AU2012212323A1 (en) 2011-02-01 2013-09-12 The Board Of Trustees Of The University Of Illinois HDAC inhibitors and therapeutic methods using the same
KR20130077390A (ko) 2011-12-29 2013-07-09 제이더블유중외제약 주식회사 단백질 키나아제 저해활성을 가지는 6-아미노-3-카복스아미도인다졸 유도체
US9783573B2 (en) 2012-09-18 2017-10-10 Bristol-Myers Squibb Company IAP antagonists
EP3580220B1 (en) 2017-02-13 2021-11-17 Bristol-Myers Squibb Company Aminotriazolopyridines as kinase inhibitors
CN111093645A (zh) 2017-07-05 2020-05-01 Cs制药技术有限公司 Egfr酪氨酸激酶的临床上重要的突变体的选择性抑制剂
DK3704118T3 (da) 2017-10-30 2022-03-14 Bristol Myers Squibb Co Aminoimidazopyrazin som kinasehæmmere
SG11202007035YA (en) 2018-01-26 2020-08-28 Bristol Myers Squibb Co Aminopyrrolotriazines as kinase inhibitors
EP3849968B1 (en) 2018-09-13 2022-12-21 Bristol-Myers Squibb Company 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1)
EP3849969B1 (en) 2018-09-13 2023-04-19 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors
AR123793A1 (es) 2020-10-19 2023-01-11 Bristol Myers Squibb Co Compuestos de triazolopiridinilo como inhibidores de quinasas

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