JP2022539148A5 - - Google Patents
Info
- Publication number
- JP2022539148A5 JP2022539148A5 JP2021577391A JP2021577391A JP2022539148A5 JP 2022539148 A5 JP2022539148 A5 JP 2022539148A5 JP 2021577391 A JP2021577391 A JP 2021577391A JP 2021577391 A JP2021577391 A JP 2021577391A JP 2022539148 A5 JP2022539148 A5 JP 2022539148A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- washing
- trishcl
- salt
- polysorbate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962868282P | 2019-06-28 | 2019-06-28 | |
| US62/868,282 | 2019-06-28 | ||
| PCT/US2020/039971 WO2020264411A1 (en) | 2019-06-28 | 2020-06-26 | Adeno-associated virus purification methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022539148A JP2022539148A (ja) | 2022-09-07 |
| JP2022539148A5 true JP2022539148A5 (enExample) | 2023-05-25 |
| JP7539420B2 JP7539420B2 (ja) | 2024-08-23 |
Family
ID=74061311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577391A Active JP7539420B2 (ja) | 2019-06-28 | 2020-06-26 | アデノ随伴ウイルスの精製方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220267796A1 (enExample) |
| EP (1) | EP3990031A4 (enExample) |
| JP (1) | JP7539420B2 (enExample) |
| CN (1) | CN114173827B (enExample) |
| TW (1) | TWI886135B (enExample) |
| WO (1) | WO2020264411A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR102198A1 (es) | 2014-10-09 | 2017-02-08 | Regeneron Pharma | Proceso para reducir partículas subvisibles en una formulación farmacéutica |
| US11020686B2 (en) | 2016-08-16 | 2021-06-01 | Regeneron Pharmaceuticals, Inc. | Methods for quantitating individual antibodies from a mixture |
| JP7102401B2 (ja) | 2016-10-25 | 2022-07-19 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | クロマトグラフィーデータ解析のための方法およびシステム |
| CA3073935A1 (en) | 2017-09-19 | 2019-03-28 | Regeneron Pharmaceuticals, Inc. | Methods of reducing particle formation and compositions formed thereby |
| TWI853823B (zh) | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| EA202192422A1 (ru) | 2019-03-05 | 2021-12-09 | Ридженерон Фармасьютикалз, Инк. | Человеческий сывороточный альбумин в составах |
| US20250027855A1 (en) * | 2022-01-03 | 2025-01-23 | Kerth Corp. | Biological kit for separating electronegative low density lipoprotein from specimen, reagent solution and method for separating electronegative low density lipoprotein from specimen |
| US20230303983A1 (en) * | 2022-03-28 | 2023-09-28 | President And Fellows Of Harvard College | High efficiency purification of divergent aav serotypes using aavx affinity chromatography |
| US20250179442A1 (en) * | 2022-03-29 | 2025-06-05 | Kaneka Corporation | Method of producing adeno-associated virus |
| CA3247416A1 (en) * | 2022-04-08 | 2023-10-12 | Csl Behring Ag | Methods of sanitizing and/or regenerating a chromatography medium |
| KR20260019635A (ko) * | 2023-06-09 | 2026-02-10 | 사르토리우스 비아이에이 세퍼레이션스 디.오.오. | 완전 충전 아데노 관련 바이러스 (aav) 캡시드의 향상된 분리 방법 |
| EP4731755A2 (en) * | 2023-06-23 | 2026-04-29 | Ultragenyx Pharmaceutical Inc. | Compositions and methods for reducing host cell proteins in recombinant adeno-associated virus preparations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7732129B1 (en) * | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| IL137510A0 (en) | 1998-02-17 | 2001-07-24 | Schering Corp | Compositions comprising viruses and methods for concentrating virus preparations |
| US6593123B1 (en) * | 2000-08-07 | 2003-07-15 | Avigen, Inc. | Large-scale recombinant adeno-associated virus (rAAV) production and purification |
| US20040106184A1 (en) * | 2002-08-28 | 2004-06-03 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
| US20070207461A1 (en) * | 2004-02-23 | 2007-09-06 | Crucell Holland B.V. | Virus Purification Methods |
| EP1783138A4 (en) * | 2004-07-27 | 2007-08-22 | Genomidea Inc | PROCESS FOR PURIFYING A VIRUS ENVELOPE |
| CN101983238B (zh) * | 2008-03-31 | 2013-06-12 | 日本烟草产业株式会社 | 病毒浓缩方法 |
| EP3054007A1 (en) * | 2015-02-09 | 2016-08-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step |
| LT3436051T (lt) * | 2016-03-31 | 2021-11-25 | Spark Therapeutics, Inc. | Kolonėlėmis pagrįstas visiškai keičiamo masto raav gavimo būdas |
| EP3731863A4 (en) * | 2017-12-29 | 2021-10-27 | Baxalta Incorporated | ADENO-ASSOCIATED VIRUS CLEANSING PROCEDURES |
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2020
- 2020-06-26 CN CN202080055070.0A patent/CN114173827B/zh active Active
- 2020-06-26 US US17/622,044 patent/US20220267796A1/en active Pending
- 2020-06-26 JP JP2021577391A patent/JP7539420B2/ja active Active
- 2020-06-26 EP EP20833341.9A patent/EP3990031A4/en active Pending
- 2020-06-26 WO PCT/US2020/039971 patent/WO2020264411A1/en not_active Ceased
- 2020-06-29 TW TW109121962A patent/TWI886135B/zh active