JP2022523679A5 - - Google Patents

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Publication number
JP2022523679A5
JP2022523679A5 JP2021543205A JP2021543205A JP2022523679A5 JP 2022523679 A5 JP2022523679 A5 JP 2022523679A5 JP 2021543205 A JP2021543205 A JP 2021543205A JP 2021543205 A JP2021543205 A JP 2021543205A JP 2022523679 A5 JP2022523679 A5 JP 2022523679A5
Authority
JP
Japan
Prior art keywords
aav
vector
composition according
composition
aav vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021543205A
Other languages
English (en)
Japanese (ja)
Other versions
JP7707066B2 (ja
JP2022523679A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/015386 external-priority patent/WO2020159970A1/en
Publication of JP2022523679A publication Critical patent/JP2022523679A/ja
Publication of JP2022523679A5 publication Critical patent/JP2022523679A5/ja
Application granted granted Critical
Publication of JP7707066B2 publication Critical patent/JP7707066B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021543205A 2019-01-28 2020-01-28 体液性免疫を回避する組成物および方法 Active JP7707066B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962797495P 2019-01-28 2019-01-28
US62/797,495 2019-01-28
US201962914682P 2019-10-14 2019-10-14
US62/914,682 2019-10-14
PCT/US2020/015386 WO2020159970A1 (en) 2019-01-28 2020-01-28 Compositions and methods for evading humoral immunity

Publications (3)

Publication Number Publication Date
JP2022523679A JP2022523679A (ja) 2022-04-26
JP2022523679A5 true JP2022523679A5 (enExample) 2023-02-03
JP7707066B2 JP7707066B2 (ja) 2025-07-14

Family

ID=71840382

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021543205A Active JP7707066B2 (ja) 2019-01-28 2020-01-28 体液性免疫を回避する組成物および方法

Country Status (8)

Country Link
US (1) US20220143213A1 (enExample)
EP (1) EP3894571A4 (enExample)
JP (1) JP7707066B2 (enExample)
KR (1) KR20210126029A (enExample)
CN (1) CN113544278A (enExample)
AU (1) AU2020215682B2 (enExample)
CA (1) CA3127950A1 (enExample)
WO (1) WO2020159970A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021067598A1 (en) 2019-10-04 2021-04-08 Ultragenyx Pharmaceutical Inc. Methods for improved therapeutic use of recombinant aav
BR112022011916A2 (pt) 2019-12-19 2022-09-06 Univ Pennsylvania Composições para tratar a ataxia de friedreich
EP4096691A1 (en) 2020-01-28 2022-12-07 Freeline Therapeutics Limited Improved assay for determining neutralising antibody titre to a viral vektor
AU2021218703A1 (en) 2020-02-14 2022-07-28 Ultragenyx Pharmaceutical Inc. Gene therapy for treating CDKL5 deficiency disorder
GB202007431D0 (en) 2020-05-19 2020-07-01 Hansa Biopharma AB Cysteine protease
EP4274592A4 (en) * 2021-01-11 2025-03-19 The Trustees of The University of Pennsylvania COMPOSITIONS FOR THE TREATMENT OF FRIEDREICH'S ATAXIA
JP2024531138A (ja) 2021-08-11 2024-08-29 ウルトラジェニックス ファーマシューティカル インコーポレイテッド 筋ジストロフィーを処置するための組成物および方法
CN117801116A (zh) * 2022-09-30 2024-04-02 上海玮美基因科技有限责任公司 一种融合型新型腺相关病毒及其应用
WO2025047848A1 (ja) 2023-08-30 2025-03-06 アステラス製薬株式会社 IdeZ改変体
WO2025245490A1 (en) * 2024-05-23 2025-11-27 Duke University Compositions comprising antibody cleaving enzymes and methods of use thereof
CN118497176B (zh) * 2024-07-16 2025-01-21 苏州康聚生物科技有限公司 一种免疫球蛋白降解酶
WO2026041758A1 (en) * 2024-08-22 2026-02-26 Genethon Modified aav capsid with enhanced transduction efficiency

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009535339A (ja) * 2006-04-28 2009-10-01 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 低下されたキャプシド免疫原性を有する改変aavベクターおよびその使用
GB201502305D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins

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