JP2022538425A5 - - Google Patents

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Publication number
JP2022538425A5
JP2022538425A5 JP2021576820A JP2021576820A JP2022538425A5 JP 2022538425 A5 JP2022538425 A5 JP 2022538425A5 JP 2021576820 A JP2021576820 A JP 2021576820A JP 2021576820 A JP2021576820 A JP 2021576820A JP 2022538425 A5 JP2022538425 A5 JP 2022538425A5
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JP
Japan
Prior art keywords
cancer
immune cell
antigen
receptor
immune
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021576820A
Other languages
English (en)
Japanese (ja)
Other versions
JP7829911B2 (ja
JP2022538425A (ja
Filing date
Publication date
Priority claimed from PCT/KR2019/010244 external-priority patent/WO2020032784A1/ko
Application filed filed Critical
Priority claimed from PCT/IB2020/056097 external-priority patent/WO2020261231A1/en
Publication of JP2022538425A publication Critical patent/JP2022538425A/ja
Publication of JP2022538425A5 publication Critical patent/JP2022538425A5/ja
Priority to JP2025076601A priority Critical patent/JP2025118764A/ja
Application granted granted Critical
Publication of JP7829911B2 publication Critical patent/JP7829911B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021576820A 2019-06-27 2020-06-26 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体 Active JP7829911B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025076601A JP2025118764A (ja) 2019-06-27 2025-05-02 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201962867503P 2019-06-27 2019-06-27
US62/867,503 2019-06-27
PCT/KR2019/010244 WO2020032784A1 (ko) 2018-08-10 2019-08-12 Hla-dr에 결합하는 키메라 항원 수용체 및 car-t 세포
KRPCT/KR2019/010244 2019-08-12
US16/715,462 US11013765B2 (en) 2018-08-10 2019-12-16 Chimeric antigen receptor that binds HLA-DR and CAR-T cell
US16/715,462 2019-12-16
US202062991493P 2020-03-18 2020-03-18
US62/991,493 2020-03-18
US202063004827P 2020-04-03 2020-04-03
US63/004,827 2020-04-03
US202063043237P 2020-06-24 2020-06-24
US63/043,237 2020-06-24
PCT/IB2020/056097 WO2020261231A1 (en) 2019-06-27 2020-06-26 Chimeric antigen receptor with 4-1bb costimulatory domain

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025076601A Division JP2025118764A (ja) 2019-06-27 2025-05-02 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体

Publications (3)

Publication Number Publication Date
JP2022538425A JP2022538425A (ja) 2022-09-02
JP2022538425A5 true JP2022538425A5 (https=) 2023-06-15
JP7829911B2 JP7829911B2 (ja) 2026-03-16

Family

ID=74061779

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021576820A Active JP7829911B2 (ja) 2019-06-27 2020-06-26 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体
JP2025076601A Withdrawn JP2025118764A (ja) 2019-06-27 2025-05-02 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025076601A Withdrawn JP2025118764A (ja) 2019-06-27 2025-05-02 ４－１ｂｂ共刺激性ドメインを有するキメラ抗原受容体

Country Status (8)

Country Link
EP (1) EP3990626A4 (https=)
JP (2) JP7829911B2 (https=)
CN (2) CN114080452B (https=)
AU (1) AU2020307673A1 (https=)
BR (1) BR112021026406A2 (https=)
CA (1) CA3144875A1 (https=)
MX (1) MX2021015967A (https=)
WO (1) WO2020261231A1 (https=)

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* Cited by examiner, † Cited by third party
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AU2019317229A1 (en) * 2018-08-10 2021-02-18 Eutilex Co.,Ltd Chimeric Antigen Receptor that Binds HLA-DR, and CAR-T Cell
TW202110873A (zh) 2019-04-30 2021-03-16 美商聖堤生物科技股份有限公司 嵌合受體及其使用方法
KR102671410B1 (ko) * 2021-03-03 2024-06-04 진화섭 RANK 리간드(RANK ligand)에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도
CN119343456A (zh) * 2022-03-15 2025-01-21 纽约基因组中心 用于改进型免疫疗法的方法和包括融合蛋白的组合物
WO2025103439A1 (zh) * 2023-11-16 2025-05-22 广州瑞风生物科技有限公司 一种嵌合抗原受体及其应用

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US20050113564A1 (en) * 2003-11-05 2005-05-26 St. Jude Children's Research Hospital Chimeric receptors with 4-1BB stimulatory signaling domain
JP4331227B2 (ja) * 2004-07-09 2009-09-16 中外製薬株式会社 抗グリピカン３抗体
AU2013204922B2 (en) * 2012-12-20 2015-05-14 Celgene Corporation Chimeric antigen receptors
US9790282B2 (en) 2013-03-25 2017-10-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
WO2015069922A2 (en) * 2013-11-06 2015-05-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Alk antibodies, conjugates, and chimeric antigen receptors, and their use
KR101605421B1 (ko) * 2014-03-05 2016-03-23 국립암센터 B 세포 림프종 세포를 특이적으로 인지하는 단일클론항체 및 이의 용도
ES2836743T3 (es) * 2014-06-02 2021-06-28 Us Health Receptores de antígeno quiméricos que seleccionan como diana CD-19
US10195272B2 (en) * 2015-03-02 2019-02-05 The Nemours Foundation Adoptive t-cell therapy using FcεRI-based chimeric antigen receptors for treating IgE-mediated allergic diseases
WO2016197064A1 (en) * 2015-06-04 2016-12-08 Epstein Alan L Lym-1 and lym-2 targeted car cell immunotherapy
JP6821688B2 (ja) * 2015-10-09 2021-01-27 ミルテニー・バイオテク・テクノロジー・インコーポレイテッドＭｉｌｔｅｎｙｉ Ｂｉｏｔｅｃ Ｔｅｃｈｎｏｌｏｇｙ， Ｉｎｃ． キメラ抗原受容体および使用方法
CN105906720A (zh) 2016-05-16 2016-08-31 武汉汉密顿生物科技股份有限公司 靶向性嵌合抗原受体修饰的免疫细胞及其制备方法和应用
CN106279438B (zh) * 2016-08-24 2019-10-22 北京领柯生物科技有限公司 新型嵌合抗原受体及其用途
CN108165568B (zh) * 2016-12-07 2020-12-08 上海恒润达生生物科技有限公司 一种培养CD19CAR-iNKT细胞方法及用途
WO2018106993A1 (en) * 2016-12-09 2018-06-14 H. Lee Moffitt Cancer Center And Research Institute Inc. Tlr9-binding chimeric antigen receptors
CA3048648A1 (en) 2017-01-10 2018-07-19 The General Hospital Corporation T cells expressing a chimeric antigen receptor
WO2018154386A1 (en) * 2017-02-21 2018-08-30 Eutilex Co., Ltd. Hla-dr car-t compositions and methods of making and using the same
US12083148B2 (en) * 2017-02-22 2024-09-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. IL13Ra2-binding chimeric antigen receptors
CN108728459B (zh) 2017-04-24 2023-08-04 上海恒润达生生物科技股份有限公司 靶向cd19的嵌合抗原受体并联合表达il-15的方法和用途
WO2018236909A1 (en) * 2017-06-20 2018-12-27 La Jolla Institute For Allergy And Immunology Engineered t-cell receptors and methods of their use in modulating inflammatory responses and treating atherosclerosis
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CN108715859B (zh) * 2018-05-31 2021-08-03 中国医学科学院血液病医院(中国医学科学院血液学研究所) 靶向cd22的嵌合抗原受体及其应用
WO2020017479A1 (ja) 2018-07-17 2020-01-23 ノイルイミューン・バイオテック株式会社 抗ｇｐｃ３一本鎖抗体を含むｃａｒ

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