JP2025511409A5 - - Google Patents

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Publication number
JP2025511409A5
JP2025511409A5 JP2024559046A JP2024559046A JP2025511409A5 JP 2025511409 A5 JP2025511409 A5 JP 2025511409A5 JP 2024559046 A JP2024559046 A JP 2024559046A JP 2024559046 A JP2024559046 A JP 2024559046A JP 2025511409 A5 JP2025511409 A5 JP 2025511409A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
sequence described
seq
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024559046A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025511409A (ja
Filing date
Publication date
Priority claimed from GBGB2204927.4A external-priority patent/GB202204927D0/en
Application filed filed Critical
Priority claimed from PCT/IB2023/053431 external-priority patent/WO2023194911A1/en
Publication of JP2025511409A publication Critical patent/JP2025511409A/ja
Publication of JP2025511409A5 publication Critical patent/JP2025511409A5/ja
Pending legal-status Critical Current

Links

JP2024559046A 2022-04-04 2023-04-04 抗メソテリンcarを発現する細胞 Pending JP2025511409A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2204927.4 2022-04-04
GBGB2204927.4A GB202204927D0 (en) 2022-04-04 2022-04-04 Cells expressing mesothelin
US202363482752P 2023-02-01 2023-02-01
US63/482,752 2023-02-01
PCT/IB2023/053431 WO2023194911A1 (en) 2022-04-04 2023-04-04 Cells expressing an anti-mesothelin car

Publications (2)

Publication Number Publication Date
JP2025511409A JP2025511409A (ja) 2025-04-15
JP2025511409A5 true JP2025511409A5 (https=) 2026-04-14

Family

ID=86328908

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024559046A Pending JP2025511409A (ja) 2022-04-04 2023-04-04 抗メソテリンcarを発現する細胞

Country Status (14)

Country Link
US (1) US20250025555A1 (https=)
EP (2) EP4628504A3 (https=)
JP (1) JP2025511409A (https=)
KR (1) KR20240168982A (https=)
CN (1) CN119110845A (https=)
AU (1) AU2023250251A1 (https=)
CA (1) CA3254719A1 (https=)
CL (2) CL2024002948A1 (https=)
CO (1) CO2024013343A2 (https=)
IL (1) IL315660A (https=)
MX (1) MX2024012314A (https=)
PE (1) PE20242282A1 (https=)
TW (1) TW202405164A (https=)
WO (1) WO2023194911A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4504247A1 (en) 2022-04-04 2025-02-12 Gammadelta Therapeutics Ltd Novel gene armoring
WO2025240496A1 (en) * 2024-05-14 2025-11-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Natural killer cells expressing a mesothelin-targeted chimeric antigen receptor and interleukin-15 for the treatment of solid tumors
WO2026069206A1 (en) * 2024-09-25 2026-04-02 Takeda Pharmaceutical Company Limited Hypoimmunogenic modified gamma delta t cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
EP1777294A1 (en) 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
US9272002B2 (en) * 2011-10-28 2016-03-01 The Trustees Of The University Of Pennsylvania Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
EP3783098A1 (en) * 2013-05-14 2021-02-24 Board Of Regents, The University Of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
US20200399383A1 (en) * 2018-02-13 2020-12-24 Novartis Ag Chimeric antigen receptor therapy in combination with il-15r and il15
TW202020145A (zh) * 2018-07-13 2020-06-01 國立大學法人京都大學 γδT細胞的製造方法
WO2020172555A1 (en) * 2019-02-21 2020-08-27 Regents Of The University Of Minnesota Genetically modified gamma delta t cells and methods of making and using
US20230159892A1 (en) * 2020-04-06 2023-05-25 Synthekine, Inc. Engineered immune cells
US20230226181A1 (en) * 2020-06-22 2023-07-20 Nanjing Legend Biotech Co., Ltd. GENETIC ENGINEERING OF gamma delta T CELLS FOR IMMUNOTHERAPY
JP7138989B1 (ja) * 2020-08-04 2022-09-20 セレンジーン インコーポレイテッド メソテリンに特異的に結合する抗メソテリンキメラ抗原受容体
JP2023540339A (ja) * 2020-09-04 2023-09-22 インパクト バイオ ユーエスエー インコーポレイテッド 癌治療に使用するためのバイシストロン性阻害性キメラ抗原受容体(iCAR)/活性化キメラ抗原受容体(aCAR)構築物
GB202013962D0 (en) * 2020-09-04 2020-10-21 Gammadelta Therapeutics Ltd Immunotherapy composition

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