JP2023518931A5 - - Google Patents

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Publication number
JP2023518931A5
JP2023518931A5 JP2022555957A JP2022555957A JP2023518931A5 JP 2023518931 A5 JP2023518931 A5 JP 2023518931A5 JP 2022555957 A JP2022555957 A JP 2022555957A JP 2022555957 A JP2022555957 A JP 2022555957A JP 2023518931 A5 JP2023518931 A5 JP 2023518931A5
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JP
Japan
Prior art keywords
immune cell
cell according
sequence
receptor
interleukin
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JP2022555957A
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English (en)
Japanese (ja)
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JP7778081B2 (ja
JP2023518931A (ja
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Priority claimed from PCT/IB2021/052292 external-priority patent/WO2021186395A1/en
Publication of JP2023518931A publication Critical patent/JP2023518931A/ja
Publication of JP2023518931A5 publication Critical patent/JP2023518931A5/ja
Application granted granted Critical
Publication of JP7778081B2 publication Critical patent/JP7778081B2/ja
Active legal-status Critical Current
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JP2022555957A 2020-03-18 2021-03-18 Il-18を分泌するgpc3 car-t細胞、並びにそれを作製する方法及び使用する方法 Active JP7778081B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062991497P 2020-03-18 2020-03-18
US62/991,497 2020-03-18
US202063004912P 2020-04-03 2020-04-03
US63/004,912 2020-04-03
US202063043401P 2020-06-24 2020-06-24
US63/043,401 2020-06-24
PCT/IB2021/052292 WO2021186395A1 (en) 2020-03-18 2021-03-18 Gpc3 car- t cells secreting il-18 and methods of making and using the same

Publications (3)

Publication Number Publication Date
JP2023518931A JP2023518931A (ja) 2023-05-09
JP2023518931A5 true JP2023518931A5 (https=) 2024-03-27
JP7778081B2 JP7778081B2 (ja) 2025-12-01

Family

ID=77768034

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022555957A Active JP7778081B2 (ja) 2020-03-18 2021-03-18 Il-18を分泌するgpc3 car-t細胞、並びにそれを作製する方法及び使用する方法

Country Status (8)

Country Link
US (1) US20230151113A1 (https=)
EP (1) EP4121517A4 (https=)
JP (1) JP7778081B2 (https=)
KR (2) KR20220155589A (https=)
CN (1) CN115461449A (https=)
AU (1) AU2021239060A1 (https=)
CA (1) CA3176125A1 (https=)
WO (1) WO2021186395A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024541076A (ja) * 2021-11-09 2024-11-06 ヤンセン バイオテツク,インコーポレーテツド T細胞受容体リガンドを特定するためのマイクロ流体共カプセル化デバイス、システム、及び方法
WO2025183436A1 (ko) * 2024-02-27 2025-09-04 (주)이노베이션바이오 Gpc3을 표적으로 하는 키메릭 항원 수용체 및 cd276을 표적으로 하는 키메릭 항원 수용체를 발현하는 면역 이펙터 세포 및 이의 용도

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2009000647A1 (es) * 2008-04-04 2010-06-04 Chugai Pharmaceutical Co Ltd Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto.
US20150329640A1 (en) * 2012-12-20 2015-11-19 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
CN104140974B (zh) * 2013-05-08 2017-09-29 科济生物医药(上海)有限公司 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞
JP2017529851A (ja) * 2014-09-26 2017-10-12 ベイラー カレッジ オブ メディスンBaylor College Of Medicine 養子免疫療法のためのグリピカン−3特異的キメラ抗原レセプター
JP7096667B2 (ja) * 2015-07-01 2022-07-06 中外製薬株式会社 Gpc3標的治療剤が有効である患者に投与されるgpc3標的治療剤
JP2019530431A (ja) * 2016-07-26 2019-10-24 テッサ・セラピューティクス・プライベート・リミテッド キメラ抗原受容体
MX2019008221A (es) * 2017-01-10 2019-12-09 Univ Yamaguchi Anticuerpo anti-gpc3.
EP3615574A4 (en) * 2017-04-26 2021-02-24 Eureka Therapeutics, Inc. SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE
US20220127570A1 (en) * 2018-05-03 2022-04-28 Cafa Therapeutics Limited Immune effector cell and use thereof
CN110468105B (zh) * 2018-05-09 2024-03-22 恺兴生命科技(上海)有限公司 表达il-18r结合蛋白的免疫效应细胞
WO2020017479A1 (ja) * 2018-07-17 2020-01-23 ノイルイミューン・バイオテック株式会社 抗gpc3一本鎖抗体を含むcar
CN115667500B (zh) * 2020-03-18 2026-02-06 优特力克斯有限公司 Gpc3 car-t细胞组合物及其制备和使用方法

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