KR20220155589A - Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법 - Google Patents

Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법 Download PDF

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KR20220155589A
KR20220155589A KR1020227035621A KR20227035621A KR20220155589A KR 20220155589 A KR20220155589 A KR 20220155589A KR 1020227035621 A KR1020227035621 A KR 1020227035621A KR 20227035621 A KR20227035621 A KR 20227035621A KR 20220155589 A KR20220155589 A KR 20220155589A
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cells
immune cell
cell
sequence
car
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Korean (ko)
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병 에스. 권
김광희
정지원
장영균
이보림
이정윤
이승현
임선우
최진경
손현태
이혜미
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주식회사 유틸렉스
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KR1020227035621A 2020-03-18 2021-03-18 Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법 Ceased KR20220155589A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257033533A KR20250154516A (ko) 2020-03-18 2021-03-18 Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062991497P 2020-03-18 2020-03-18
US62/991,497 2020-03-18
US202063004912P 2020-04-03 2020-04-03
US63/004,912 2020-04-03
US202063043401P 2020-06-24 2020-06-24
US63/043,401 2020-06-24
PCT/IB2021/052292 WO2021186395A1 (en) 2020-03-18 2021-03-18 Gpc3 car- t cells secreting il-18 and methods of making and using the same

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KR1020257033533A Division KR20250154516A (ko) 2020-03-18 2021-03-18 Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법

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KR20220155589A true KR20220155589A (ko) 2022-11-23

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KR1020227035621A Ceased KR20220155589A (ko) 2020-03-18 2021-03-18 Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법
KR1020257033533A Pending KR20250154516A (ko) 2020-03-18 2021-03-18 Il-18을 분비하는 gpc3 car-t 세포 및 이의 제조 및 사용 방법

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US (1) US20230151113A1 (https=)
EP (1) EP4121517A4 (https=)
JP (1) JP7778081B2 (https=)
KR (2) KR20220155589A (https=)
CN (1) CN115461449A (https=)
AU (1) AU2021239060A1 (https=)
CA (1) CA3176125A1 (https=)
WO (1) WO2021186395A1 (https=)

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JP2024541076A (ja) * 2021-11-09 2024-11-06 ヤンセン バイオテツク,インコーポレーテツド T細胞受容体リガンドを特定するためのマイクロ流体共カプセル化デバイス、システム、及び方法
WO2025183436A1 (ko) * 2024-02-27 2025-09-04 (주)이노베이션바이오 Gpc3을 표적으로 하는 키메릭 항원 수용체 및 cd276을 표적으로 하는 키메릭 항원 수용체를 발현하는 면역 이펙터 세포 및 이의 용도

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CL2009000647A1 (es) * 2008-04-04 2010-06-04 Chugai Pharmaceutical Co Ltd Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto.
US20150329640A1 (en) * 2012-12-20 2015-11-19 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
CN104140974B (zh) * 2013-05-08 2017-09-29 科济生物医药(上海)有限公司 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞
JP2017529851A (ja) * 2014-09-26 2017-10-12 ベイラー カレッジ オブ メディスンBaylor College Of Medicine 養子免疫療法のためのグリピカン−3特異的キメラ抗原レセプター
JP7096667B2 (ja) * 2015-07-01 2022-07-06 中外製薬株式会社 Gpc3標的治療剤が有効である患者に投与されるgpc3標的治療剤
JP2019530431A (ja) * 2016-07-26 2019-10-24 テッサ・セラピューティクス・プライベート・リミテッド キメラ抗原受容体
MX2019008221A (es) * 2017-01-10 2019-12-09 Univ Yamaguchi Anticuerpo anti-gpc3.
EP3615574A4 (en) * 2017-04-26 2021-02-24 Eureka Therapeutics, Inc. SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE
US20220127570A1 (en) * 2018-05-03 2022-04-28 Cafa Therapeutics Limited Immune effector cell and use thereof
CN110468105B (zh) * 2018-05-09 2024-03-22 恺兴生命科技(上海)有限公司 表达il-18r结合蛋白的免疫效应细胞
WO2020017479A1 (ja) * 2018-07-17 2020-01-23 ノイルイミューン・バイオテック株式会社 抗gpc3一本鎖抗体を含むcar
CN115667500B (zh) * 2020-03-18 2026-02-06 优特力克斯有限公司 Gpc3 car-t细胞组合物及其制备和使用方法

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WO2021186395A1 (en) 2021-09-23
EP4121517A4 (en) 2024-08-07
US20230151113A1 (en) 2023-05-18
JP7778081B2 (ja) 2025-12-01
CN115461449A (zh) 2022-12-09
JP2023518931A (ja) 2023-05-09
CA3176125A1 (en) 2021-09-23
EP4121517A1 (en) 2023-01-25
KR20250154516A (ko) 2025-10-28
AU2021239060A1 (en) 2022-10-06

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