JP2021520788A5 - - Google Patents

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Publication number
JP2021520788A5
JP2021520788A5 JP2020555033A JP2020555033A JP2021520788A5 JP 2021520788 A5 JP2021520788 A5 JP 2021520788A5 JP 2020555033 A JP2020555033 A JP 2020555033A JP 2020555033 A JP2020555033 A JP 2020555033A JP 2021520788 A5 JP2021520788 A5 JP 2021520788A5
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JP
Japan
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seq
amino acid
sequence
cell
vector
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JP2020555033A
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English (en)
Japanese (ja)
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JP2021520788A (ja
JP7479290B2 (ja
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Priority claimed from PCT/US2019/026840 external-priority patent/WO2019200007A1/en
Publication of JP2021520788A publication Critical patent/JP2021520788A/ja
Publication of JP2021520788A5 publication Critical patent/JP2021520788A5/ja
Application granted granted Critical
Publication of JP7479290B2 publication Critical patent/JP7479290B2/ja
Active legal-status Critical Current
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JP2020555033A 2018-04-10 2019-04-10 Ｄｌｌ３に対するキメラ受容体及びその使用方法 Active JP7479290B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862655725P 2018-04-10 2018-04-10
US62/655,725 2018-04-10
PCT/US2019/026840 WO2019200007A1 (en) 2018-04-10 2019-04-10 Chimeric receptors to dll3 and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2021520788A JP2021520788A (ja) 2021-08-26
JP2021520788A5 true JP2021520788A5 (https=) 2022-04-18
JP7479290B2 JP7479290B2 (ja) 2024-05-08

Family

ID=66248863

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JP2020555033A Active JP7479290B2 (ja) 2018-04-10 2019-04-10 Ｄｌｌ３に対するキメラ受容体及びその使用方法

Country Status (27)

Country Link
US (1) US12012462B2 (https=)
EP (1) EP3773912A1 (https=)
JP (1) JP7479290B2 (https=)
KR (1) KR102951376B1 (https=)
CN (1) CN112334193A (https=)
AR (1) AR114283A1 (https=)
AU (2) AU2019251473A1 (https=)
BR (1) BR112020020857A2 (https=)
CA (1) CA3095920A1 (https=)
CL (3) CL2020002613A1 (https=)
CO (1) CO2020013392A2 (https=)
CR (1) CR20200539A (https=)
EA (1) EA202092417A1 (https=)
IL (1) IL277735A (https=)
JO (1) JOP20200259A1 (https=)
MA (1) MA52203A (https=)
MX (1) MX2020010753A (https=)
MY (1) MY203383A (https=)
PE (1) PE20211396A1 (https=)
PH (1) PH12020551671A1 (https=)
SA (1) SA520420301B1 (https=)
SG (1) SG11202009923TA (https=)
TW (1) TWI842703B (https=)
UA (1) UA129466C2 (https=)
UY (1) UY38182A (https=)
WO (1) WO2019200007A1 (https=)
ZA (1) ZA202006943B (https=)

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EP4527466A3 (en) 2019-07-17 2025-06-18 Legend Biotech Ireland Limited Anti-dll3 chimeric antigen receptors and uses thereof
JP2023504884A (ja) * 2019-12-05 2023-02-07 ヴィセリックス・インコーポレーティッド ユニバーサル細胞療法のための免疫逃避機構のモジュレーター
CN115298223A (zh) 2020-03-12 2022-11-04 南京传奇生物科技有限公司 磷脂酰肌醇蛋白聚糖-2结合部分、嵌合抗原受体及其用途
TW202200615A (zh) 2020-03-12 2022-01-01 美商安進公司 用於治療和預防患者的crs之方法
EP4313081A4 (en) * 2021-04-02 2025-04-09 Nanjing Legend Biotech Co., Ltd. MANIPULATED IMMUNE CELLS AND THEIR USES
MX2023012614A (es) * 2021-05-08 2023-11-03 Shanghai Qilu Pharmaceutical Res And Development Centre Ltd Molecula de union contra dll3 y uso de la misma.
IL307646A (en) * 2021-05-10 2023-12-01 Amgen Inc Dosing regimen for combination therapy targeting DLL3 and PD-1
JP2024525727A (ja) 2021-07-14 2024-07-12 ２セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたｔ細胞受容体
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CA3255500A1 (en) 2022-04-08 2023-10-12 Regeneron Pharmaceuticals, Inc. MULTI-PART RECEIVERS AND SIGNALING COMPLEXES
WO2023199069A1 (en) 2022-04-14 2023-10-19 Crescendo Biologics Limited Chimeric antigen receptor that binds mesothelin
KR20250057777A (ko) 2022-07-25 2025-04-29 인테리우스 바이오테라퓨틱스, 인코포레이티드 돌연변이된 폴리펩티드, 이를 포함하는 조성물, 및 그 용도(mutated polypeptides, compositions comprising the same, and uses thereof)
CN116003628A (zh) * 2022-08-15 2023-04-25 南京博安生物技术有限公司 靶向人dll3抗原的全人源特异性嵌合抗原受体及其应用
CN116813784B (zh) * 2023-05-17 2024-03-01 星奕昂(上海)生物科技有限公司 靶向dll3的抗体及其应用
AU2024347905A1 (en) * 2023-09-26 2026-04-02 Legend Biotech Ireland Limited Dll3 binding moieties and uses thereof
WO2025082340A1 (zh) * 2023-10-16 2025-04-24 上海先博生物科技有限公司 一种靶向δ样配体3的CAR及应用
GB202402046D0 (en) 2024-02-14 2024-03-27 Bivictrix Ltd Therapeutic antibodies
GB202402048D0 (en) 2024-02-14 2024-03-27 Bivictrix Ltd Therapeutic antibodies
WO2025202653A1 (en) 2024-03-27 2025-10-02 Ucl Business Ltd T-cell therapy targetting mutant calreticulin
WO2026039940A1 (zh) * 2024-08-19 2026-02-26 南京博安生物技术有限公司 一种增强型靶向dll3蛋白的嵌合抗原受体和突变体以及应用
GB202412771D0 (en) 2024-08-30 2024-10-16 Cambridge Entpr Ltd Therapeutic molecules

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