JP2021530233A5 - - Google Patents
Info
- Publication number
- JP2021530233A5 JP2021530233A5 JP2021502538A JP2021502538A JP2021530233A5 JP 2021530233 A5 JP2021530233 A5 JP 2021530233A5 JP 2021502538 A JP2021502538 A JP 2021502538A JP 2021502538 A JP2021502538 A JP 2021502538A JP 2021530233 A5 JP2021530233 A5 JP 2021530233A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- sequence
- seq
- acid residues
- region
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862700178P | 2018-07-18 | 2018-07-18 | |
| US62/700,178 | 2018-07-18 | ||
| PCT/US2019/042245 WO2020018695A1 (en) | 2018-07-18 | 2019-07-17 | Chimeric receptors to steap1 and methods of use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021530233A JP2021530233A (ja) | 2021-11-11 |
| JP2021530233A5 true JP2021530233A5 (https=) | 2022-07-26 |
| JPWO2020018695A5 JPWO2020018695A5 (https=) | 2022-07-26 |
| JP7459046B2 JP7459046B2 (ja) | 2024-04-01 |
Family
ID=67515138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502538A Active JP7459046B2 (ja) | 2018-07-18 | 2019-07-17 | Ｓｔｅａｐ１に対するキメラ受容体及びその使用方法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20210277148A1 (https=) |
| EP (1) | EP3823993A1 (https=) |
| JP (1) | JP7459046B2 (https=) |
| KR (2) | KR102914114B1 (https=) |
| CN (2) | CN112771080B (https=) |
| AR (1) | AR117950A1 (https=) |
| AU (1) | AU2019307607B2 (https=) |
| BR (1) | BR112021000914A2 (https=) |
| CA (1) | CA3106653A1 (https=) |
| CL (3) | CL2021000136A1 (https=) |
| CO (1) | CO2021000660A2 (https=) |
| CR (1) | CR20210091A (https=) |
| EA (1) | EA202190304A1 (https=) |
| IL (2) | IL324856A (https=) |
| JO (1) | JOP20210011A1 (https=) |
| MA (1) | MA53167A (https=) |
| MX (2) | MX2021000617A (https=) |
| PE (1) | PE20210315A1 (https=) |
| PH (1) | PH12021550120A1 (https=) |
| SA (1) | SA521421049B1 (https=) |
| SG (1) | SG11202100464UA (https=) |
| TW (2) | TWI860294B (https=) |
| UY (1) | UY38309A (https=) |
| WO (1) | WO2020018695A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202519260A (zh) * | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
| US20250041339A1 (en) * | 2021-11-19 | 2025-02-06 | The Trustees Of The University Of Pennsylvania | Engineered Pan-Leukocyte Antigen CD45 to Facilityate CAR T Cell Therapy |
| JP2025508371A (ja) * | 2022-02-11 | 2025-03-26 | フレッド ハッチンソン キャンサー センター | Ｓｔｅａｐ１に結合するキメラ抗原受容体 |
| GB202208119D0 (en) * | 2022-06-01 | 2022-07-13 | Univ Oslo Hf | Anti-steap1 car |
| CN116178532B (zh) * | 2023-01-30 | 2025-04-04 | 中国科学院武汉病毒研究所 | 一种古尔图病毒核蛋白的单克隆抗体及其应用 |
| WO2024238832A2 (en) * | 2023-05-16 | 2024-11-21 | Fred Hutchinson Cancer Center | Pro-inflammatory cytokine enhanced steap1 recombinant receptors |
| WO2025090749A1 (en) * | 2023-10-25 | 2025-05-01 | St. Jude Children's Research Hospital, Inc. | Chimeric antigen receptors targeting leucine rich repeat containing 15 (lrrc15) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US5834266A (en) | 1993-02-12 | 1998-11-10 | President & Fellows Of Harvard College | Regulated apoptosis |
| US5830462A (en) | 1993-02-12 | 1998-11-03 | President & Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US5869337A (en) | 1993-02-12 | 1999-02-09 | President And Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US20030036654A1 (en) | 1994-08-18 | 2003-02-20 | Holt Dennis A. | Synthetic multimerizing agents |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| AU757698C (en) * | 1998-06-01 | 2004-04-08 | Agensys, Inc. | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
| WO2000023573A2 (en) * | 1998-10-20 | 2000-04-27 | City Of Hope | Cd20-specific redirected t cells and their use in cellular immunotherapy of cd20+ malignancies |
| CA2406864A1 (en) | 2000-02-24 | 2001-08-30 | Life Technologies Corporation | Simultaneous stimulation and concentration of cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US7446190B2 (en) * | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| US20100196336A1 (en) | 2006-05-23 | 2010-08-05 | Dongsu Park | Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods |
| KR20140116546A (ko) * | 2006-10-27 | 2014-10-02 | 제넨테크, 인크. | 항체 및 면역접합체 및 이들의 용도 |
| WO2011146862A1 (en) | 2010-05-21 | 2011-11-24 | Bellicum Pharmaceuticals, Inc. | Methods for inducing selective apoptosis |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| AU2012209103B2 (en) | 2011-01-26 | 2015-12-03 | Takeda Pharmaceutical Company Limited | Methods and compositions for the synthesis of multimerizing agents |
| CN110200997A (zh) | 2011-03-23 | 2019-09-06 | 弗雷德哈钦森癌症研究中心 | 用于细胞免疫治疗的方法和组合物 |
| EP2906684B8 (en) * | 2012-10-10 | 2020-09-02 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| EP4303232A3 (en) | 2013-02-15 | 2024-04-17 | The Regents of The University of California | Chimeric antigen receptor and methods of use thereof |
| WO2014151960A2 (en) | 2013-03-14 | 2014-09-25 | Bellicum Pharmaceuticals, Inc. | Methods for controlling t cell proliferation |
| WO2014165818A2 (en) * | 2013-04-05 | 2014-10-09 | T Cell Therapeutics, Inc. | Compositions and methods for preventing and treating prostate cancer |
| ES2897579T3 (es) * | 2013-06-10 | 2022-03-01 | Dana Farber Cancer Inst Inc | Métodos y composiciones para reducir la inmunosupresión por células tumorales |
| WO2015017214A1 (en) | 2013-07-29 | 2015-02-05 | Bluebird Bio, Inc. | Multipartite signaling proteins and uses thereof |
| US10287354B2 (en) | 2013-12-20 | 2019-05-14 | Novartis Ag | Regulatable chimeric antigen receptor |
| US20160333108A1 (en) * | 2014-01-13 | 2016-11-17 | Stephen J. Forman | CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE |
| US20170043034A1 (en) * | 2014-01-24 | 2017-02-16 | Genentech, Inc. | Methods of using anti-steap1 antibodies and immunoconjugates |
| US10934346B2 (en) | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| WO2016025454A2 (en) * | 2014-08-12 | 2016-02-18 | Anthrogenesis Corporation | Car-t lymphocytes engineered to home to lymph node b cell zone, skin, or gastrointestinal tract |
| WO2016081518A2 (en) * | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
| CN108064246A (zh) * | 2015-06-15 | 2018-05-22 | 基因泰克公司 | 抗体和免疫结合物 |
| WO2017055388A2 (en) * | 2015-10-02 | 2017-04-06 | F. Hoffmann-La Roche Ag | Bispecific t cell activating antigen binding molecules |
| GB201518136D0 (en) * | 2015-10-14 | 2015-11-25 | Glaxosmithkline Ip Dev Ltd | Novel chimeric antigen receptors |
| CN110352068A (zh) * | 2016-12-02 | 2019-10-18 | 南加利福尼亚大学 | 合成的免疫受体及其使用方法 |
| TW202519260A (zh) * | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
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2019
- 2019-07-17 EA EA202190304A patent/EA202190304A1/ru unknown
- 2019-07-17 PE PE2021000076A patent/PE20210315A1/es unknown
- 2019-07-17 KR KR1020217004607A patent/KR102914114B1/ko active Active
- 2019-07-17 CR CR20210091A patent/CR20210091A/es unknown
- 2019-07-17 KR KR1020267001194A patent/KR20260017491A/ko active Pending
- 2019-07-17 MA MA053167A patent/MA53167A/fr unknown
- 2019-07-17 CN CN201980060357.XA patent/CN112771080B/zh active Active
- 2019-07-17 SG SG11202100464UA patent/SG11202100464UA/en unknown
- 2019-07-17 IL IL324856A patent/IL324856A/en unknown
- 2019-07-17 WO PCT/US2019/042245 patent/WO2020018695A1/en not_active Ceased
- 2019-07-17 EP EP19749064.2A patent/EP3823993A1/en active Pending
- 2019-07-17 CN CN202411003355.6A patent/CN118955734A/zh active Pending
- 2019-07-17 JO JOP/2021/0011A patent/JOP20210011A1/ar unknown
- 2019-07-17 CA CA3106653A patent/CA3106653A1/en active Pending
- 2019-07-17 US US17/260,977 patent/US20210277148A1/en not_active Abandoned
- 2019-07-17 MX MX2021000617A patent/MX2021000617A/es unknown
- 2019-07-17 BR BR112021000914-0A patent/BR112021000914A2/pt unknown
- 2019-07-17 JP JP2021502538A patent/JP7459046B2/ja active Active
- 2019-07-17 IL IL280238A patent/IL280238B2/en unknown
- 2019-07-17 AU AU2019307607A patent/AU2019307607B2/en active Active
- 2019-07-18 TW TW108125431A patent/TWI860294B/zh active
- 2019-07-18 AR ARP190102027A patent/AR117950A1/es unknown
- 2019-07-18 TW TW113144512A patent/TWI902538B/zh active
- 2019-07-19 UY UY0001038309A patent/UY38309A/es active IP Right Grant
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2021
- 2021-01-15 PH PH12021550120A patent/PH12021550120A1/en unknown
- 2021-01-15 MX MX2025015568A patent/MX2025015568A/es unknown
- 2021-01-17 SA SA521421049A patent/SA521421049B1/ar unknown
- 2021-01-18 CL CL2021000136A patent/CL2021000136A1/es unknown
- 2021-01-22 CO CONC2021/0000660A patent/CO2021000660A2/es unknown
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2023
- 2023-10-25 CL CL2023003182A patent/CL2023003182A1/es unknown
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2024
- 2024-12-30 CL CL2024004076A patent/CL2024004076A1/es unknown