JP2022527860A5 - - Google Patents

Info

Publication number
JP2022527860A5
JP2022527860A5 JP2021560390A JP2021560390A JP2022527860A5 JP 2022527860 A5 JP2022527860 A5 JP 2022527860A5 JP 2021560390 A JP2021560390 A JP 2021560390A JP 2021560390 A JP2021560390 A JP 2021560390A JP 2022527860 A5 JP2022527860 A5 JP 2022527860A5
Authority
JP
Japan
Prior art keywords
chain
sequence
antigen
chains
binding site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021560390A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022527860A (ja
JP7716623B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/026261 external-priority patent/WO2020206033A1/en
Publication of JP2022527860A publication Critical patent/JP2022527860A/ja
Publication of JP2022527860A5 publication Critical patent/JP2022527860A5/ja
Application granted granted Critical
Publication of JP7716623B2 publication Critical patent/JP7716623B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021560390A 2019-04-02 2020-04-01 排出ポンプ-癌抗原マルチ特異性抗体ならびにそれに関する組成物、試薬、キットおよび方法 Active JP7716623B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962828044P 2019-04-02 2019-04-02
US62/828,044 2019-04-02
US202062967478P 2020-01-29 2020-01-29
US62/967,478 2020-01-29
PCT/US2020/026261 WO2020206033A1 (en) 2019-04-02 2020-04-01 Efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto

Publications (3)

Publication Number Publication Date
JP2022527860A JP2022527860A (ja) 2022-06-06
JP2022527860A5 true JP2022527860A5 (https=) 2023-03-31
JP7716623B2 JP7716623B2 (ja) 2025-08-01

Family

ID=70465444

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021560390A Active JP7716623B2 (ja) 2019-04-02 2020-04-01 排出ポンプ-癌抗原マルチ特異性抗体ならびにそれに関する組成物、試薬、キットおよび方法

Country Status (10)

Country Link
US (1) US12331121B2 (https=)
EP (1) EP3946626A1 (https=)
JP (1) JP7716623B2 (https=)
KR (1) KR20220004653A (https=)
CN (1) CN113692413A (https=)
AU (1) AU2020253449A1 (https=)
BR (1) BR112021019701A2 (https=)
CA (1) CA3131895A1 (https=)
MX (1) MX2021012003A (https=)
WO (1) WO2020206033A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021155028A1 (en) * 2020-01-29 2021-08-05 Kenjockety Biotechnology, Inc. Anti-mdr1 antibodies and uses thereof
CN112656941A (zh) * 2021-01-20 2021-04-16 福建医科大学附属协和医院 抗cd47单克隆抗体在制备抗阿霉素耐药的急性淋巴细胞白血病细胞的药物中应用
WO2022167999A1 (en) * 2021-02-08 2022-08-11 Takeda Pharmaceutical Company Limited Combination therapy for cancer treatment
US20250051471A1 (en) * 2021-12-13 2025-02-13 William Robert Arathoon Living Trust Dated August 29, 2016 Anti-Abcb1 Antibodies
WO2023159220A1 (en) 2022-02-18 2023-08-24 Kenjockety Biotechnology, Inc. Anti-cd47 antibodies
KR20250044267A (ko) * 2022-07-28 2025-03-31 선전 엔듀어링 바이오테크 리미티드 Peg 기반 항-cd47/항-pd-l1 이중특이적 항체-약물 접합체
WO2024130249A2 (en) * 2022-12-16 2024-06-20 Washington University Compositions and methods of treatment for neuroinflammation-related disorders
WO2025155776A1 (en) * 2024-01-19 2025-07-24 Amgen Inc. Expression vector systems with two copies of light chain

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
JP2564412B2 (ja) * 1990-03-02 1996-12-18 財団法人癌研究会 薬剤耐性癌に対するキメラ抗体およびその製造
WO1992008802A1 (en) 1990-10-29 1992-05-29 Cetus Oncology Corporation Bispecific antibodies, method of production, and uses thereof
US5849877A (en) 1990-10-29 1998-12-15 Chiron Corporation Antigen-binding sites of antibody molecules specific for cancer antigens
US5948647A (en) * 1990-10-29 1999-09-07 Chiron Corporation Nucleic acids encoding antigen-binding sites specific for cancer antigens
TW197439B (https=) 1991-04-04 1993-01-01 Ueno Pharmaceutics Applic Res Co Ltd
DE69233013T2 (de) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
US5283253A (en) 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
WO1993010076A1 (en) 1991-11-22 1993-05-27 The University Of Mississippi Synthesis and optical resolution of the taxol side chain and related compounds
ATE207080T1 (de) 1991-11-25 2001-11-15 Enzon Inc Multivalente antigen-bindende proteine
US5200534A (en) 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
FR2688514A1 (fr) 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
JPH08500973A (ja) 1992-05-21 1996-02-06 ザ ペン ステイト リサーチ ファウンデーション タキソール、関連タキサン及び他の新規な抗癌/抗ウイルス性化合物原料としてのイチイ培養組織
US5274137A (en) 1992-06-23 1993-12-28 Nicolaou K C Intermediates for preparation of taxols
US5294637A (en) 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5202448A (en) 1992-08-14 1993-04-13 Napro Biotherapeutics, Inc. Processes of converting taxanes into baccatin III
CA2100808A1 (en) 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
FR2696461B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
FR2696458B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696462B1 (fr) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
FR2696464B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2696463B1 (fr) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
EP1024198A3 (en) 1992-12-03 2002-05-29 Genzyme Corporation Pseudo-adenoviral vectors for the gene therapy of haemophiliae
US5279949A (en) 1992-12-07 1994-01-18 Board Of Trustees Operating Michigan State University Process for the isolation and purification of taxol and taxanes from Taxus spp
EP0705344B8 (en) 1993-06-24 2006-05-10 Advec Inc. Adenovirus vectors for gene therapy
US5824701A (en) 1993-10-20 1998-10-20 Enzon, Inc. Taxane-based prodrugs
AU687117B2 (en) 1993-10-25 1998-02-19 Canji, Inc. Recombinant adenoviral vector and methods of use
US5415869A (en) 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
AU3740997A (en) 1996-08-26 1998-03-19 Bristol-Myers Squibb Company Sulfenamide taxane derivatives
WO1998013059A1 (en) 1996-09-27 1998-04-02 Bristol-Myers Squibb Company Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
AU4966597A (en) 1996-11-19 1998-06-10 Daiichi Pharmaceutical Co., Ltd. Taxol derivatives
US5977386A (en) 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US7951917B1 (en) 1997-05-02 2011-05-31 Genentech, Inc. Method for making multispecific antibodies having heteromultimeric and common components
JP2002505682A (ja) 1997-06-20 2002-02-19 ベーカー ノートン ファーマシューティカルズ インコーポレイテッド パクリタクセルの可溶性プロドラッグ
US7288665B1 (en) 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
US6080849A (en) 1997-09-10 2000-06-27 Vion Pharmaceuticals, Inc. Genetically modified tumor-targeted bacteria with reduced virulence
JPH1192468A (ja) 1997-09-17 1999-04-06 Yakult Honsha Co Ltd 新規なタキサン誘導体
WO1999018113A1 (fr) 1997-10-08 1999-04-15 Bio Research Corporation Of Yokohama Derives taxoides et leur procede de production
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
EP1865987A2 (en) * 2005-04-06 2007-12-19 Cedars-Sinai Medical Center Inhibition of p-glycoprotein by treatment with a class of modulators and the uic2 monoclonal antibody
PT2569013T (pt) * 2010-05-14 2017-02-08 Univ Leland Stanford Junior Anticorpos monoclonais humanizados e quiméricos para cd47
BR112016000853A2 (pt) * 2013-07-16 2017-12-12 Genentech Inc métodos para tratar ou retardar, reduzir ou inibir a recidiva ou a progressão do câncer e a progressão de uma doença imune-relacionada em um indivíduo, para aumentar, melhorar ou estimular uma resposta ou função imune em um indivíduo e kit
CN110655582B (zh) * 2015-01-08 2022-12-16 江苏康宁杰瑞生物制药有限公司 具有共同轻链的双特异性抗体或抗体混合物

Similar Documents

Publication Publication Date Title
JP2022527860A5 (https=)
JP2021527431A5 (https=)
JP2025111463A5 (https=)
JP2022101693A5 (https=)
JP2023002615A5 (https=)
JP2024522360A5 (https=)
JP2017535257A5 (https=)
JP2020516240A5 (https=)
JP2022542165A5 (https=)
JP2008532949A5 (https=)
JP2020502271A5 (https=)
RU2015141428A (ru) Антитела, связывающие il-4 и/или il-13, и их применение
JP2025183307A5 (https=)
JP2009529920A5 (https=)
JP2020501598A5 (https=)
JP2023531185A5 (https=)
JP2022533538A5 (https=)
JP2020500834A5 (https=)
JP2021515798A5 (https=)
JP2012532851A5 (https=)
JP2023506750A5 (https=)
JP2017521054A5 (https=)
RU2017114968A (ru) Связывающие молекулы, а именно антитела, способные связываться с l1cam (cd171)
JP2023512196A5 (https=)
JP2023528416A5 (https=)