JP2023531185A5 - - Google Patents

Info

Publication number
JP2023531185A5
JP2023531185A5 JP2022577477A JP2022577477A JP2023531185A5 JP 2023531185 A5 JP2023531185 A5 JP 2023531185A5 JP 2022577477 A JP2022577477 A JP 2022577477A JP 2022577477 A JP2022577477 A JP 2022577477A JP 2023531185 A5 JP2023531185 A5 JP 2023531185A5
Authority
JP
Japan
Prior art keywords
seq
antibody
sequence
nos
antibody fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022577477A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531185A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/037364 external-priority patent/WO2021257525A1/en
Publication of JP2023531185A publication Critical patent/JP2023531185A/ja
Publication of JP2023531185A5 publication Critical patent/JP2023531185A5/ja
Pending legal-status Critical Current

Links

JP2022577477A 2020-06-18 2021-06-15 条件的に活性な抗ネクチン4抗体 Pending JP2023531185A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063040894P 2020-06-18 2020-06-18
US63/040,894 2020-06-18
US202163166062P 2021-03-25 2021-03-25
US63/166,062 2021-03-25
PCT/US2021/037364 WO2021257525A1 (en) 2020-06-18 2021-06-15 Conditionally active anti-nectin-4 antibodies

Publications (2)

Publication Number Publication Date
JP2023531185A JP2023531185A (ja) 2023-07-21
JP2023531185A5 true JP2023531185A5 (https=) 2024-06-18

Family

ID=79268274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022577477A Pending JP2023531185A (ja) 2020-06-18 2021-06-15 条件的に活性な抗ネクチン4抗体

Country Status (11)

Country Link
US (1) US20230235054A1 (https=)
EP (1) EP4168453A4 (https=)
JP (1) JP2023531185A (https=)
KR (1) KR20230038711A (https=)
CN (1) CN115768798A (https=)
AU (1) AU2021293183A1 (https=)
CA (1) CA3182395A1 (https=)
IL (1) IL298903A (https=)
MX (1) MX2022016192A (https=)
TW (1) TWI901704B (https=)
WO (1) WO2021257525A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4096717B1 (en) 2020-01-31 2024-12-11 Innate Pharma Treatment of cancer
MX2023005873A (es) * 2020-11-25 2023-06-05 Innate Pharma Tratamiento del cancer.
KR20240026496A (ko) * 2021-06-29 2024-02-28 엘피스 바이오파마슈티컬즈 항-넥틴4 항체 및 이를 포함하는 다중특이적 단백질 복합체
EP4463483A4 (en) * 2022-01-12 2025-05-21 Navi Bio-Therapeutics, Inc. ANTIBODY SPECIFIC TO NECTIN CELL ADHESION MOLECULE 4 AND USES THEREOF
CN116063498A (zh) * 2022-04-27 2023-05-05 博际生物医药科技(杭州)有限公司 单域抗Nectin-4抗体
WO2024012541A1 (zh) * 2022-07-14 2024-01-18 百奥泰生物制药股份有限公司 抗Nectin-4抗体药物偶联物及应用
WO2024012536A1 (zh) * 2022-07-14 2024-01-18 百奥泰生物制药股份有限公司 抗Nectin-4抗体、其抗体药物偶联物及应用
EP4688851A1 (en) 2023-03-27 2026-02-11 LAVA Therapeutics N.V. Nectin-4 binding agents and methods of use
EP4438624A1 (en) 2023-03-27 2024-10-02 LAVA Therapeutics N.V. Antibodies that bind nectin-4 and gamma-delta t cell receptors
TW202530249A (zh) * 2023-09-29 2025-08-01 美商雅克提斯腫瘤學公司 小蛋白、結合物及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3803790B2 (ja) * 2003-02-17 2006-08-02 株式会社東北テクノアーチ 新規なダイアボディ型二重特異性抗体
US20110301056A1 (en) * 2008-12-12 2011-12-08 Oncotherapy Science, Inc. Nectin-4 for target genes of cancer therapy and diagnosis
MX347954B (es) * 2010-09-29 2017-05-19 Agensys Inc Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12.
EP3347048B1 (en) * 2015-09-09 2020-04-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Antibodies having specificity to nectin-4 and uses thereof
WO2017078839A1 (en) * 2015-11-02 2017-05-11 Bioatla, Llc Conditionally active polypeptides
AU2017320874B2 (en) * 2016-08-31 2024-03-07 Bioatla, Llc Conditionally active polypeptides and methods of generating them
WO2018226578A1 (en) * 2017-06-05 2018-12-13 Agensys, Inc. Nectin-4-binding proteins and methods of use thereof
KR102892725B1 (ko) * 2018-05-09 2025-12-01 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. 인간 넥틴4에 특이적인 항체
WO2019241216A1 (en) * 2018-06-14 2019-12-19 Bioatla, Llc Multi-specific antibody constructs

Similar Documents

Publication Publication Date Title
JP2023531185A5 (https=)
JP7685095B2 (ja) 多重特異性抗体とその作製及び使用方法
JP2022101693A5 (https=)
Hong et al. Chemoenzymatic Synthesis of a Rhamnose‐Functionalized Bispecific Nanobody as a Bispecific Antibody Mimic for Cancer Immunotherapy
JP2021527431A5 (https=)
JP7399852B2 (ja) 多重特異性抗体とその作製及び使用方法
JP2021530987A5 (https=)
JP2020502271A5 (https=)
RU2019138067A (ru) Биспецифическое антитело против ox40 и ctla-4
JP2017535257A5 (https=)
CN106659779A (zh) 双特异性四价抗体及其制造和使用方法
IL291545B1 (en) Anti-CTLA4 antibodies, antibody fragments, immunoconjugates thereof and uses thereof
JP2019524640A5 (https=)
JP2022553922A5 (https=)
JP2019512207A5 (https=)
US12053530B2 (en) Plectin-1 binding antibodies and uses thereof
JP2024542192A5 (https=)
JP2023502876A5 (https=)
JP2024508749A (ja) クローンt細胞増殖を処置するための方法および材料
JP2020533002A5 (https=)
JP2023511403A5 (https=)
JP2025506248A5 (https=)
US20250034252A1 (en) Manabodies targeting p53 tumor antigens and methods of using
JP2023531189A5 (https=)
CN119677777A (zh) 抗cd28抗体