JP2022526818A5 - - Google Patents
Info
- Publication number
- JP2022526818A5 JP2022526818A5 JP2021559658A JP2021559658A JP2022526818A5 JP 2022526818 A5 JP2022526818 A5 JP 2022526818A5 JP 2021559658 A JP2021559658 A JP 2021559658A JP 2021559658 A JP2021559658 A JP 2021559658A JP 2022526818 A5 JP2022526818 A5 JP 2022526818A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- butyl
- tetrahydro
- butanoic acid
- naphthyrizin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024188930A JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962831060P | 2019-04-08 | 2019-04-08 | |
| US62/831,060 | 2019-04-08 | ||
| US201962850530P | 2019-05-20 | 2019-05-20 | |
| US62/850,530 | 2019-05-20 | ||
| US201962899071P | 2019-09-11 | 2019-09-11 | |
| US62/899,071 | 2019-09-11 | ||
| PCT/US2020/027335 WO2020210404A1 (en) | 2019-04-08 | 2020-04-08 | Dosage forms and regimens for amino acid compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188930A Division JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022526818A JP2022526818A (ja) | 2022-05-26 |
| JP2022526818A5 true JP2022526818A5 (https=) | 2023-04-14 |
| JP7579805B2 JP7579805B2 (ja) | 2024-11-08 |
Family
ID=72750659
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559658A Active JP7579805B2 (ja) | 2019-04-08 | 2020-04-08 | アミノ酸化合物の剤形およびレジメン |
| JP2024188930A Pending JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188930A Pending JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11419869B2 (https=) |
| EP (1) | EP3952902A4 (https=) |
| JP (2) | JP7579805B2 (https=) |
| CN (1) | CN114173803A (https=) |
| AU (1) | AU2020273158A1 (https=) |
| IL (1) | IL287004B2 (https=) |
| SG (1) | SG11202110889WA (https=) |
| WO (1) | WO2020210404A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3509590A4 (en) | 2016-09-07 | 2020-12-02 | Pliant Therapeutics, Inc. | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE |
| US10696672B2 (en) | 2016-12-23 | 2020-06-30 | Pliant Therapeutics, Inc. | Amino acid compounds and methods of use |
| MX394210B (es) | 2017-02-28 | 2025-03-04 | Morphic Therapeutic Inc | INHIBIDORES DE INTEGRINA AVß6. |
| MA52117A (fr) | 2017-02-28 | 2022-04-06 | Morphic Therapeutic Inc | Inhibiteurs de l'intégrine (alpha-v) (bêta-6) |
| FI3761980T3 (fi) | 2018-03-07 | 2024-02-21 | Pliant Therapeutics Inc | Aminohappoyhdisteitä ja käyttömenetelmiä |
| TWI841573B (zh) | 2018-06-27 | 2024-05-11 | 美商普萊恩醫療公司 | 具有未分支連接子之胺基酸化合物及使用方法 |
| SI3844162T1 (sl) | 2018-08-29 | 2025-06-30 | Morphic Therapeutic, Inc. | Zaviralci integrina alfa v beta6 |
| WO2020047239A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | INHIBITING αV β6 INTEGRIN |
| WO2020047208A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| TW202028179A (zh) | 2018-10-08 | 2020-08-01 | 美商普萊恩醫療公司 | 胺基酸化合物及使用方法 |
| CN114173803A (zh) | 2019-04-08 | 2022-03-11 | 普利安特治疗公司 | 氨基酸化合物的剂型和方案 |
| EP4247472A4 (en) | 2020-11-19 | 2024-10-09 | Pliant Therapeutics, Inc. | INTEGRIN INHIBITORS AND USES THEREOF |
| WO2022165000A1 (en) * | 2021-01-27 | 2022-08-04 | Shy Therapeutics, Llc | Methods for the treatment of fibrotic disease |
| US20240124483A1 (en) * | 2021-01-27 | 2024-04-18 | Shy Therapeutics, Llc | Methods for the Treatment of Fibrotic Disease |
| MX2023012794A (es) * | 2021-04-30 | 2023-12-15 | Pliant Therapeutics Inc | Regímenes de dosificación expandidos para inhibidores de integrina. |
| TW202329973A (zh) * | 2021-10-14 | 2023-08-01 | 美商普萊恩醫療公司 | 整合素抑制劑及其與其他藥劑併用之用途 |
| JP2025518533A (ja) * | 2022-05-18 | 2025-06-17 | プライアント・セラピューティクス・インコーポレイテッド | インテグリン阻害剤の安定化 |
| CN120091811A (zh) * | 2022-07-09 | 2025-06-03 | 普利安特治疗公司 | 整合素抑制剂及其与其它药剂组合的用途 |
| EP4626878A1 (en) | 2022-12-02 | 2025-10-08 | Neumora Therapeutics, Inc. | Methods of treating neurological disorders |
| WO2024125634A1 (zh) * | 2022-12-16 | 2024-06-20 | 西藏海思科制药有限公司 | 一种四氢萘啶类化合物及其在医药上的应用 |
| WO2025067384A1 (zh) * | 2023-09-28 | 2025-04-03 | 成都微芯药业有限公司 | 一类氨基酸整联蛋白抑制剂、其制备方法及其应用 |
| US20250197393A1 (en) | 2023-12-14 | 2025-06-19 | Pliant Therapeutics, Inc. | Integrin inhibitor and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048861A (en) * | 1997-12-17 | 2000-04-11 | Merck & Co., Inc. | Integrin receptor antagonists |
| KR20010033248A (ko) | 1997-12-17 | 2001-04-25 | 폴락 돈나 엘. | 인테그린 수용체 길항제 |
| MXPA03011046A (es) | 2001-06-01 | 2004-06-25 | Elan Pharm Inc | Hidroxialquilaminas. |
| EP1537072A1 (en) | 2002-09-10 | 2005-06-08 | Pharmacia & Upjohn Company LLC | Substituted aminoethers for the treatment of alzheimer s disease |
| ES2416354T3 (es) | 2005-06-21 | 2013-07-31 | Ajinomoto Co., Inc. | Cristal de derivado de fenilalanina, método de producción del mismo y uso del mismo |
| WO2014015054A1 (en) * | 2012-07-18 | 2014-01-23 | Saint Louis University | Beta amino acid derivatives as integrin antagonists |
| WO2015048819A1 (en) | 2013-09-30 | 2015-04-02 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| WO2016145258A1 (en) | 2015-03-10 | 2016-09-15 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| EP3442352A4 (en) | 2016-04-14 | 2020-03-11 | Mars, Incorporated | COMPOUNDS FOR MODULATING THE ACTIVITY OF CALCIUM-SENSITIVE RECEPTORS FOR MODULATING THE TASTE OF KOKUMI AND ANIMAL FEED PRODUCTS THEREFORE |
| US11192889B2 (en) | 2016-07-05 | 2021-12-07 | The Rockefeller University | Tetrahydronaphthyridinepentanamide integrin antagonists |
| EP3509590A4 (en) | 2016-09-07 | 2020-12-02 | Pliant Therapeutics, Inc. | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE |
| US10696672B2 (en) | 2016-12-23 | 2020-06-30 | Pliant Therapeutics, Inc. | Amino acid compounds and methods of use |
| MX394210B (es) | 2017-02-28 | 2025-03-04 | Morphic Therapeutic Inc | INHIBIDORES DE INTEGRINA AVß6. |
| MA52117A (fr) | 2017-02-28 | 2022-04-06 | Morphic Therapeutic Inc | Inhibiteurs de l'intégrine (alpha-v) (bêta-6) |
| WO2019118938A1 (en) | 2017-12-15 | 2019-06-20 | Apellis Pharmaceuticals, Inc. | Dosing regimens and related compositions and methods |
| FI3761980T3 (fi) * | 2018-03-07 | 2024-02-21 | Pliant Therapeutics Inc | Aminohappoyhdisteitä ja käyttömenetelmiä |
| TWI841573B (zh) | 2018-06-27 | 2024-05-11 | 美商普萊恩醫療公司 | 具有未分支連接子之胺基酸化合物及使用方法 |
| WO2020047239A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | INHIBITING αV β6 INTEGRIN |
| WO2020047208A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| WO2020047207A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutics, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| TW202028179A (zh) | 2018-10-08 | 2020-08-01 | 美商普萊恩醫療公司 | 胺基酸化合物及使用方法 |
| CN114173803A (zh) | 2019-04-08 | 2022-03-11 | 普利安特治疗公司 | 氨基酸化合物的剂型和方案 |
| WO2021097338A1 (en) | 2019-11-15 | 2021-05-20 | Pliant Therapeutics, Inc. | Compositions and methods for activation of integrins |
| CN115989235A (zh) | 2020-05-07 | 2023-04-18 | 普利安特治疗公司 | 使用氨基酸化合物治疗呼吸系统疾病的方法 |
| EP4247472A4 (en) | 2020-11-19 | 2024-10-09 | Pliant Therapeutics, Inc. | INTEGRIN INHIBITORS AND USES THEREOF |
| MX2023012794A (es) | 2021-04-30 | 2023-12-15 | Pliant Therapeutics Inc | Regímenes de dosificación expandidos para inhibidores de integrina. |
| US20240350494A1 (en) | 2021-09-03 | 2024-10-24 | Pliant Therapeutics, Inc. | Therapeutic modulation of integrins |
| TW202329973A (zh) | 2021-10-14 | 2023-08-01 | 美商普萊恩醫療公司 | 整合素抑制劑及其與其他藥劑併用之用途 |
| JP2025518533A (ja) | 2022-05-18 | 2025-06-17 | プライアント・セラピューティクス・インコーポレイテッド | インテグリン阻害剤の安定化 |
| CN120091811A (zh) | 2022-07-09 | 2025-06-03 | 普利安特治疗公司 | 整合素抑制剂及其与其它药剂组合的用途 |
| IL321740A (en) | 2022-12-27 | 2025-08-01 | Pliant Therapeutics Inc | Alpha-V-beta-8 integrin inhibitors and their uses |
| WO2024155965A2 (en) | 2023-01-21 | 2024-07-25 | Pliant Therapeutics, Inc. | Biomarkers for use in integrin inhibitor therapy |
-
2020
- 2020-04-08 CN CN202080041929.2A patent/CN114173803A/zh active Pending
- 2020-04-08 IL IL287004A patent/IL287004B2/en unknown
- 2020-04-08 WO PCT/US2020/027335 patent/WO2020210404A1/en not_active Ceased
- 2020-04-08 AU AU2020273158A patent/AU2020273158A1/en not_active Abandoned
- 2020-04-08 JP JP2021559658A patent/JP7579805B2/ja active Active
- 2020-04-08 SG SG11202110889WA patent/SG11202110889WA/en unknown
- 2020-04-08 US US16/843,824 patent/US11419869B2/en active Active
- 2020-04-08 EP EP20786790.4A patent/EP3952902A4/en not_active Withdrawn
-
2022
- 2022-07-20 US US17/869,758 patent/US12390463B2/en active Active
-
2024
- 2024-10-28 JP JP2024188930A patent/JP2025028835A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022526818A5 (https=) | ||
| JP2021119140A5 (https=) | ||
| JP2021529755A5 (https=) | ||
| JP2024517765A5 (https=) | ||
| JP2022508657A5 (https=) | ||
| HRP20240234T1 (hr) | Aminokiselinski spojevi i postupci za uporabu | |
| JP7012152B2 (ja) | Ｆｓｈｄの治療のためにｄｕｘ４および下流遺伝子発現を低減するｐ３８キナーゼ阻害剤 | |
| KR101976218B1 (ko) | 4-히드록시부티르산 중수소화 유사체 | |
| JP6581320B2 (ja) | 腫瘍治療用医薬組成物 | |
| CN105593215B (zh) | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 | |
| TW200413375A (en) | Kinase inhibitors | |
| JP2002519379A (ja) | 関節症を治療するためのファルネシルタンパク質トランスフェラーゼ阻害剤 | |
| EA027689B1 (ru) | Трифторметилзамещенные аннелированные пиримидины и их применение | |
| JP5679811B2 (ja) | キナーゼカスケードを調節するための組成物の調製のための方法ならびにその使用方法 | |
| JP2020517698A5 (https=) | ||
| JP2002541108A (ja) | 炎症性疾患治療用フタラジン誘導体 | |
| US9776973B2 (en) | Deuterated momelotinib | |
| TW200831102A (en) | 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use | |
| JP7606530B2 (ja) | コロナウイルス感染症による化学感覚機能障害の治療 | |
| TWI324066B (en) | A pharmaceutical composition for inhibiting cell migration induced by an angiogenic factor | |
| KR20200103031A (ko) | 신규한 mtor 저해제 화합물 | |
| JP7025555B2 (ja) | 一過性受容体電位ａ１イオンチャネルの阻害 | |
| CN114206871B (zh) | 1-(6-(甲氧基)哒嗪-3-基)环丙烷-1-甲酰胺衍生物作为自分泌运动因子(atx)调节剂治疗发炎性气道疾病 | |
| JP2022551580A5 (https=) | ||
| WO2018005328A1 (en) | Deuterated bictegravir |