JP2022526818A5 - - Google Patents
Info
- Publication number
- JP2022526818A5 JP2022526818A5 JP2021559658A JP2021559658A JP2022526818A5 JP 2022526818 A5 JP2022526818 A5 JP 2022526818A5 JP 2021559658 A JP2021559658 A JP 2021559658A JP 2021559658 A JP2021559658 A JP 2021559658A JP 2022526818 A5 JP2022526818 A5 JP 2022526818A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- butyl
- tetrahydro
- butanoic acid
- naphthyrizin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024188930A JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962831060P | 2019-04-08 | 2019-04-08 | |
| US62/831,060 | 2019-04-08 | ||
| US201962850530P | 2019-05-20 | 2019-05-20 | |
| US62/850,530 | 2019-05-20 | ||
| US201962899071P | 2019-09-11 | 2019-09-11 | |
| US62/899,071 | 2019-09-11 | ||
| PCT/US2020/027335 WO2020210404A1 (en) | 2019-04-08 | 2020-04-08 | Dosage forms and regimens for amino acid compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188930A Division JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022526818A JP2022526818A (ja) | 2022-05-26 |
| JP2022526818A5 true JP2022526818A5 (enExample) | 2023-04-14 |
| JP7579805B2 JP7579805B2 (ja) | 2024-11-08 |
Family
ID=72750659
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559658A Active JP7579805B2 (ja) | 2019-04-08 | 2020-04-08 | アミノ酸化合物の剤形およびレジメン |
| JP2024188930A Pending JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188930A Pending JP2025028835A (ja) | 2019-04-08 | 2024-10-28 | アミノ酸化合物の剤形およびレジメン |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11419869B2 (enExample) |
| EP (1) | EP3952902A4 (enExample) |
| JP (2) | JP7579805B2 (enExample) |
| CN (1) | CN114173803A (enExample) |
| AU (1) | AU2020273158A1 (enExample) |
| IL (1) | IL287004B2 (enExample) |
| SG (1) | SG11202110889WA (enExample) |
| WO (1) | WO2020210404A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109996541A (zh) | 2016-09-07 | 2019-07-09 | 普利安特治疗公司 | N-酰基氨基酸化合物及其使用方法 |
| US10696672B2 (en) | 2016-12-23 | 2020-06-30 | Pliant Therapeutics, Inc. | Amino acid compounds and methods of use |
| EP4159727B1 (en) | 2017-02-28 | 2026-04-08 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| US11046685B2 (en) | 2017-02-28 | 2021-06-29 | Morphic Therapeutic, Inc. | Inhibitors of (α-v)(β-6) integrin |
| CU24684B1 (es) | 2018-03-07 | 2023-10-06 | Pliant Therapeutics Inc | Compuestos de aminoácidos como inhibidores de la integrina |
| TWI841573B (zh) | 2018-06-27 | 2024-05-11 | 美商普萊恩醫療公司 | 具有未分支連接子之胺基酸化合物及使用方法 |
| AU2019327475B2 (en) | 2018-08-29 | 2025-06-05 | Morphic Therapeutic, Inc. | INHIBITING αV β6 INTEGRIN |
| WO2020047208A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| PT3844162T (pt) | 2018-08-29 | 2025-03-28 | Morphic Therapeutic Inc | Inibidores da integrina alfa v beta6 |
| TW202028179A (zh) | 2018-10-08 | 2020-08-01 | 美商普萊恩醫療公司 | 胺基酸化合物及使用方法 |
| EP3952902A4 (en) | 2019-04-08 | 2022-12-21 | Pliant Therapeutics, Inc. | DOSAGE FORMS AND THERAPY SCHEMES FOR AMINO ACID COMPOUNDS |
| TW202235417A (zh) * | 2020-11-19 | 2022-09-16 | 美商普萊恩醫療公司 | 整合素抑制劑及其用途 |
| WO2022165000A1 (en) * | 2021-01-27 | 2022-08-04 | Shy Therapeutics, Llc | Methods for the treatment of fibrotic disease |
| US20240124483A1 (en) * | 2021-01-27 | 2024-04-18 | Shy Therapeutics, Llc | Methods for the Treatment of Fibrotic Disease |
| US20230028658A1 (en) * | 2021-04-30 | 2023-01-26 | Pliant Therapeutics, Inc. | Expanded dosage regimens for integrin inhibitors |
| JP2024539645A (ja) * | 2021-10-14 | 2024-10-29 | プライアント・セラピューティクス・インコーポレイテッド | インテグリン阻害剤及び他の薬剤と組み合わせたその使用 |
| WO2023225119A1 (en) * | 2022-05-18 | 2023-11-23 | Pliant Therapeutics, Inc. | Stabilization of integrin inhibitors |
| US20240122930A1 (en) * | 2022-07-09 | 2024-04-18 | Pliant Therapeutics, Inc. | Integrin inhibitors and uses thereof in combination with other agents |
| EP4626878A1 (en) | 2022-12-02 | 2025-10-08 | Neumora Therapeutics, Inc. | Methods of treating neurological disorders |
| WO2024125634A1 (zh) * | 2022-12-16 | 2024-06-20 | 西藏海思科制药有限公司 | 一种四氢萘啶类化合物及其在医药上的应用 |
| WO2025067384A1 (zh) * | 2023-09-28 | 2025-04-03 | 成都微芯药业有限公司 | 一类氨基酸整联蛋白抑制剂、其制备方法及其应用 |
| US20250197393A1 (en) | 2023-12-14 | 2025-06-19 | Pliant Therapeutics, Inc. | Integrin inhibitor and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK9192000A3 (en) | 1997-12-17 | 2001-03-12 | Merck & Co Inc | Integrin receptor antagonists |
| US6048861A (en) * | 1997-12-17 | 2000-04-11 | Merck & Co., Inc. | Integrin receptor antagonists |
| ATE396174T1 (de) | 2001-06-01 | 2008-06-15 | Elan Pharm Inc | Hydroxyalkylaminderivate als beta-secretase- inhibitoren und deren verwendung zur behandlung der alzheimerschen krankheit oder ähnlicher krankheiten |
| AU2003273310A1 (en) | 2002-09-10 | 2004-04-30 | Pharmacia And Upjohn | Substituted aminoethers for the treatment of alzheimer's disease |
| ES2416354T3 (es) | 2005-06-21 | 2013-07-31 | Ajinomoto Co., Inc. | Cristal de derivado de fenilalanina, método de producción del mismo y uso del mismo |
| IN2015DN00099A (enExample) * | 2012-07-18 | 2015-05-29 | Univ Saint Louis | |
| AU2014324426A1 (en) | 2013-09-30 | 2016-04-21 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| AU2016228852A1 (en) | 2015-03-10 | 2017-10-19 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| JP7170540B2 (ja) | 2016-04-14 | 2022-11-14 | マース インコーポレーテッド | コク味を調節するためにカルシウム感知受容体活性を調節する化合物及びそれを含むペットフード製品 |
| KR20190026001A (ko) | 2016-07-05 | 2019-03-12 | 더 락커펠러 유니버시티 | 테트라하이드로나프티리딘펜탄아미드 인테그린 길항물질 |
| CN109996541A (zh) | 2016-09-07 | 2019-07-09 | 普利安特治疗公司 | N-酰基氨基酸化合物及其使用方法 |
| US10696672B2 (en) | 2016-12-23 | 2020-06-30 | Pliant Therapeutics, Inc. | Amino acid compounds and methods of use |
| EP4159727B1 (en) | 2017-02-28 | 2026-04-08 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| US11046685B2 (en) | 2017-02-28 | 2021-06-29 | Morphic Therapeutic, Inc. | Inhibitors of (α-v)(β-6) integrin |
| JP2021507884A (ja) | 2017-12-15 | 2021-02-25 | アペリス・ファーマシューティカルズ・インコーポレイテッドＡｐｅｌｌｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 投与レジメンならびに関連組成物および方法 |
| CU24684B1 (es) | 2018-03-07 | 2023-10-06 | Pliant Therapeutics Inc | Compuestos de aminoácidos como inhibidores de la integrina |
| TWI841573B (zh) | 2018-06-27 | 2024-05-11 | 美商普萊恩醫療公司 | 具有未分支連接子之胺基酸化合物及使用方法 |
| AU2019327475B2 (en) | 2018-08-29 | 2025-06-05 | Morphic Therapeutic, Inc. | INHIBITING αV β6 INTEGRIN |
| WO2020047208A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| EP3843728B1 (en) | 2018-08-29 | 2025-04-30 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| TW202028179A (zh) | 2018-10-08 | 2020-08-01 | 美商普萊恩醫療公司 | 胺基酸化合物及使用方法 |
| EP3952902A4 (en) | 2019-04-08 | 2022-12-21 | Pliant Therapeutics, Inc. | DOSAGE FORMS AND THERAPY SCHEMES FOR AMINO ACID COMPOUNDS |
| CN115151566A (zh) | 2019-11-15 | 2022-10-04 | 普利安特治疗公司 | 用于活化整合素的组合物和方法 |
| KR20230049584A (ko) | 2020-05-07 | 2023-04-13 | 플라이언트 테라퓨틱스, 인크. | 아미노산 화합물을 사용한 호흡기 질환의 치료 |
| TW202235417A (zh) | 2020-11-19 | 2022-09-16 | 美商普萊恩醫療公司 | 整合素抑制劑及其用途 |
| US20230028658A1 (en) | 2021-04-30 | 2023-01-26 | Pliant Therapeutics, Inc. | Expanded dosage regimens for integrin inhibitors |
| US20240350494A1 (en) | 2021-09-03 | 2024-10-24 | Pliant Therapeutics, Inc. | Therapeutic modulation of integrins |
| JP2024539645A (ja) | 2021-10-14 | 2024-10-29 | プライアント・セラピューティクス・インコーポレイテッド | インテグリン阻害剤及び他の薬剤と組み合わせたその使用 |
| WO2023225119A1 (en) | 2022-05-18 | 2023-11-23 | Pliant Therapeutics, Inc. | Stabilization of integrin inhibitors |
| US20240122930A1 (en) | 2022-07-09 | 2024-04-18 | Pliant Therapeutics, Inc. | Integrin inhibitors and uses thereof in combination with other agents |
| WO2024145245A2 (en) | 2022-12-27 | 2024-07-04 | Pliant Therapeutics, Inc. | Alpha-v-beta-8 integrin inhibitors and uses thereof |
| WO2024155965A2 (en) | 2023-01-21 | 2024-07-25 | Pliant Therapeutics, Inc. | Biomarkers for use in integrin inhibitor therapy |
-
2020
- 2020-04-08 EP EP20786790.4A patent/EP3952902A4/en not_active Withdrawn
- 2020-04-08 CN CN202080041929.2A patent/CN114173803A/zh active Pending
- 2020-04-08 WO PCT/US2020/027335 patent/WO2020210404A1/en not_active Ceased
- 2020-04-08 AU AU2020273158A patent/AU2020273158A1/en not_active Abandoned
- 2020-04-08 SG SG11202110889WA patent/SG11202110889WA/en unknown
- 2020-04-08 IL IL287004A patent/IL287004B2/en unknown
- 2020-04-08 JP JP2021559658A patent/JP7579805B2/ja active Active
- 2020-04-08 US US16/843,824 patent/US11419869B2/en active Active
-
2022
- 2022-07-20 US US17/869,758 patent/US12390463B2/en active Active
-
2024
- 2024-10-28 JP JP2024188930A patent/JP2025028835A/ja active Pending
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