JP2022525925A5 - - Google Patents

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Publication number
JP2022525925A5
JP2022525925A5 JP2021556481A JP2021556481A JP2022525925A5 JP 2022525925 A5 JP2022525925 A5 JP 2022525925A5 JP 2021556481 A JP2021556481 A JP 2021556481A JP 2021556481 A JP2021556481 A JP 2021556481A JP 2022525925 A5 JP2022525925 A5 JP 2022525925A5
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JP
Japan
Prior art keywords
tcr
modified
chain
functional fragment
polynucleotide
Prior art date
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Application number
JP2021556481A
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English (en)
Japanese (ja)
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JP2022525925A (ja
JP7680032B2 (ja
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Priority claimed from PCT/IB2020/000140 external-priority patent/WO2020188348A2/en
Publication of JP2022525925A publication Critical patent/JP2022525925A/ja
Publication of JP2022525925A5 publication Critical patent/JP2022525925A5/ja
Application granted granted Critical
Publication of JP7680032B2 publication Critical patent/JP7680032B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021556481A 2019-03-18 2020-03-17 A2/ny-eso-1特異的t細胞受容体およびその使用 Active JP7680032B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819988P 2019-03-18 2019-03-18
US62/819,988 2019-03-18
PCT/IB2020/000140 WO2020188348A2 (en) 2019-03-18 2020-03-17 A2/ny-eso-1 specific t cell receptors and uses thereof

Publications (3)

Publication Number Publication Date
JP2022525925A JP2022525925A (ja) 2022-05-20
JP2022525925A5 true JP2022525925A5 (enExample) 2023-03-17
JP7680032B2 JP7680032B2 (ja) 2025-05-20

Family

ID=70465122

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021556481A Active JP7680032B2 (ja) 2019-03-18 2020-03-17 A2/ny-eso-1特異的t細胞受容体およびその使用

Country Status (7)

Country Link
US (2) US12473346B2 (enExample)
EP (1) EP3941939A2 (enExample)
JP (1) JP7680032B2 (enExample)
CN (1) CN113906140B (enExample)
AU (1) AU2020243431B2 (enExample)
CA (1) CA3134102A1 (enExample)
WO (1) WO2020188348A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
WO2022067005A1 (en) * 2020-09-27 2022-03-31 Genentech, Inc. High throughput multiparametric immune cell engager screening assay
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
US20240207319A1 (en) 2021-05-06 2024-06-27 Ludwig Institute For Cancer Research Ltd Compositions and methods for immunotherapy
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を治療するための方法
EP4374872A1 (en) * 2022-11-22 2024-05-29 Koninklijke Philips N.V. Pde enhanced car-t cells

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078334A1 (en) 1999-06-17 2000-12-28 University Of Maryland Biotechnology Institute Chimeric chemokine-antigen polypeptides and uses therefor
IL160359A0 (en) 2001-08-31 2004-07-25 Avidex Ltd Soluble t cell receptor
AU2005246073B2 (en) 2004-05-19 2010-10-28 Adaptimmune Limited Method of improving T cell receptors
ATE417065T1 (de) 2004-05-19 2008-12-15 Medigene Ltd Hochaffiner ny-eso-t-zellen-rezeptor
US9963510B2 (en) 2005-04-15 2018-05-08 Macrogenics, Inc. Covalent diabodies and uses thereof
ES2971647T3 (es) 2005-04-15 2024-06-06 Macrogenics Inc Diacuerpos covalentes y usos de los mismos
US8088379B2 (en) * 2006-09-26 2012-01-03 The United States Of America As Represented By The Department Of Health And Human Services Modified T cell receptors and related materials and methods
WO2008037943A1 (en) 2006-09-29 2008-04-03 Medigene Limited Cells transformed with nucleic acid encoding ny-eso t cell receptors
CA2700278A1 (en) * 2007-09-25 2009-04-02 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Modified t cell receptors and related materials and methods
GB0908613D0 (en) 2009-05-20 2009-06-24 Immunocore Ltd T Cell Reseptors
ES2816647T3 (es) 2012-01-17 2021-04-05 Univ Leland Stanford Junior Reactivos SIRP-alfa de alta afinidad
CN113684185A (zh) 2013-02-26 2021-11-23 纪念斯隆-凯特琳癌症中心 用于免疫疗法的组合物和方法
US20170335331A1 (en) 2014-10-31 2017-11-23 The Trustees Of The University Of Pennsylvania Altering Gene Expression in CART Cells and Uses Thereof
US20210206826A1 (en) * 2015-11-19 2021-07-08 The Regents Of The University Of California Conditionally repressible immune cell receptors and methods of use thereof
GB201522592D0 (en) 2015-12-22 2016-02-03 Immunocore Ltd T cell receptors
GB201616238D0 (en) 2016-09-23 2016-11-09 Adaptimmune Ltd Modified T cells
CN108456247A (zh) * 2017-02-20 2018-08-28 上海恒润达生生物科技有限公司 靶向ny-eso-1的t细胞受体及其用途

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