JP2022523786A - ピラジン誘導体およびｓｈｐ２の阻害の際のその適用 - Google Patents

ピラジン誘導体およびｓｈｐ２の阻害の際のその適用 Download PDF

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JP2022523786A
JP2022523786A JP2021551865A JP2021551865A JP2022523786A JP 2022523786 A JP2022523786 A JP 2022523786A JP 2021551865 A JP2021551865 A JP 2021551865A JP 2021551865 A JP2021551865 A JP 2021551865A JP 2022523786 A JP2022523786 A JP 2022523786A
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alkoxy
membered
alkyl
halogen
mmol
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JPWO2020177653A5 (enExample
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スン，ハイフォン
ワン，クイフォン
ジャン，タオ
マー，モンナン
リュー，ジンチャン
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スージョウ ゲンハウス ファーマシューティカル シーオー．，エルティディー
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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JP2021551865A 2019-03-04 2020-03-02 ピラジン誘導体およびｓｈｐ２の阻害の際のその適用 Pending JP2022523786A (ja)

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Application Number Priority Date Filing Date Title
CN201910160960.7 2019-03-04
CN201910160960.7A CN111647000B (zh) 2019-03-04 2019-03-04 吡嗪类衍生物及其在抑制shp2中的应用
PCT/CN2020/077391 WO2020177653A1 (zh) 2019-03-04 2020-03-02 吡嗪类衍生物及其在抑制shp2中的应用

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JP2022523786A true JP2022523786A (ja) 2022-04-26
JPWO2020177653A5 JPWO2020177653A5 (enExample) 2022-11-02

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US (3) US12338246B2 (enExample)
EP (1) EP3936502A4 (enExample)
JP (1) JP2022523786A (enExample)
KR (1) KR20210135561A (enExample)
CN (2) CN111647000B (enExample)
AU (1) AU2020233038B2 (enExample)
BR (1) BR112021017495A2 (enExample)
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Cited By (1)

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JP2023530838A (ja) * 2020-06-22 2023-07-20 スーチュアン・コールン－バイオテック・バイオファーマシューティカル・カンパニー・リミテッド 置換されたピラジン化合物、当該化合物を含む医薬組成物、及びその使用

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WO2022006780A1 (en) * 2020-07-08 2022-01-13 Novartis Ag Manufacture of compounds and compositions for inhibiting activity of shp2
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TW202309052A (zh) 2021-05-05 2023-03-01 美商銳新醫藥公司 Ｒａｓ抑制劑
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TW202244049A (zh) * 2021-05-12 2022-11-16 大陸商藥雅科技（上海）有限公司 Shp2磷酸酶抑制劑的製備及其應用
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