JP2022523301A5 - - Google Patents
Info
- Publication number
- JP2022523301A5 JP2022523301A5 JP2021543226A JP2021543226A JP2022523301A5 JP 2022523301 A5 JP2022523301 A5 JP 2022523301A5 JP 2021543226 A JP2021543226 A JP 2021543226A JP 2021543226 A JP2021543226 A JP 2021543226A JP 2022523301 A5 JP2022523301 A5 JP 2022523301A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- angptl7
- position corresponding
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024213170A JP2025023307A (ja) | 2019-01-23 | 2024-12-06 | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795665P | 2019-01-23 | 2019-01-23 | |
| US62/795,665 | 2019-01-23 | ||
| US201962880609P | 2019-07-30 | 2019-07-30 | |
| US62/880,609 | 2019-07-30 | ||
| US201962902683P | 2019-09-19 | 2019-09-19 | |
| US62/902,683 | 2019-09-19 | ||
| US201962909573P | 2019-10-02 | 2019-10-02 | |
| US62/909,573 | 2019-10-02 | ||
| PCT/US2020/014373 WO2020154268A2 (en) | 2019-01-23 | 2020-01-21 | Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024213170A Division JP2025023307A (ja) | 2019-01-23 | 2024-12-06 | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523301A JP2022523301A (ja) | 2022-04-22 |
| JP2022523301A5 true JP2022523301A5 (enExample) | 2023-01-30 |
Family
ID=69591771
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543226A Pending JP2022523301A (ja) | 2019-01-23 | 2020-01-21 | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
| JP2024213170A Pending JP2025023307A (ja) | 2019-01-23 | 2024-12-06 | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024213170A Pending JP2025023307A (ja) | 2019-01-23 | 2024-12-06 | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11767526B2 (enExample) |
| EP (1) | EP3914711A2 (enExample) |
| JP (2) | JP2022523301A (enExample) |
| KR (1) | KR20210132045A (enExample) |
| CN (1) | CN113646432A (enExample) |
| AU (1) | AU2020210630C1 (enExample) |
| CA (1) | CA3126476A1 (enExample) |
| IL (1) | IL284700B2 (enExample) |
| MX (1) | MX2021008797A (enExample) |
| SG (1) | SG11202107497XA (enExample) |
| WO (1) | WO2020154268A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| MX2021008797A (es) | 2019-01-23 | 2022-01-31 | Regeneron Pharma | Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7). |
| JP2022535717A (ja) | 2019-05-24 | 2022-08-10 | エンピリコ インク． | アンジオポエチン様７（ａｎｇｐｔｌ７）関連疾患の処置 |
| US20230357774A1 (en) * | 2020-09-29 | 2023-11-09 | Empirico Inc. | Compositions and methods for the treatment of angiopoietin like 7 (angptl7) related diseases |
| WO2022115383A1 (en) * | 2020-11-24 | 2022-06-02 | Empirico Inc. | Treatment of sos2 related diseases and disorders |
| US11865134B2 (en) | 2021-02-26 | 2024-01-09 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (ANGPTL7) inhibitors |
| KR20240099232A9 (ko) * | 2021-09-30 | 2025-12-10 | 리제너론 파마슈티칼스 인코포레이티드 | Rho 구아닌 뉴클레오타이드 교환 인자 12[Rho Guanine Nucleotide Exchange Factor 12, ARHGEF12] 억제제를 이용한 녹내장 치료 |
| JP2024538646A (ja) * | 2021-10-01 | 2024-10-23 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | ＡＮＧＰＴＬ７を標的化するためのｉＲＮＡ組成物および方法 |
| EP4453210A1 (en) * | 2021-12-22 | 2024-10-30 | Regeneron Pharmaceuticals, Inc. | Treatment of kidney diseases with angiopoietin like 3 (angptl3) inhibitors |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE033977T2 (en) | 2004-08-23 | 2018-02-28 | Sylentis Sau | Treatment of eye disorders with siRNAs characterized by increased intraocular pressure |
| WO2008004719A1 (en) | 2006-07-05 | 2008-01-10 | Orientbio Co., Ltd | Method for diagnosing cancer by detecting the methylation of transitional zones |
| CN102481271A (zh) | 2009-05-11 | 2012-05-30 | 博格生物系统有限责任公司 | 利用表观代谢转变剂、多维细胞内分子或环境影响剂治疗代谢障碍的方法 |
| US8642737B2 (en) | 2010-07-26 | 2014-02-04 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| EP3093029A1 (en) | 2009-07-27 | 2016-11-16 | Baxalta GmbH | Blood coagulation protein conjugates |
| JP5909755B2 (ja) | 2009-07-27 | 2016-04-27 | リポクセン テクノロジーズ リミテッド | 非血液凝固タンパク質の糖ポリシアル酸化 |
| US8809501B2 (en) | 2009-07-27 | 2014-08-19 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| ES2597954T3 (es) | 2009-07-27 | 2017-01-24 | Baxalta GmbH | Conjugados de proteína de la coagulación sanguínea |
| EP2494351B1 (en) | 2009-10-26 | 2016-06-08 | Externautics S.p.A. | Colon and rectal tumor markers and methods of use thereof |
| NZ600268A (en) | 2010-01-11 | 2014-08-29 | Genomic Health Inc | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| EP2397559A1 (en) | 2010-06-17 | 2011-12-21 | Max-Delbrück-Centrum Für Molekulare Medizin | Stage-specific biomarkers for the diagnosis of acute kidney injury |
| US20120010230A1 (en) | 2010-07-08 | 2012-01-12 | Macdougall John R | Methods and compositions for identification, assessment and treatment of cancers associated with hedgehog signaling |
| TR201908836T4 (tr) | 2010-07-30 | 2019-07-22 | Baxalta GmbH | Oksim bağına yönelik nükleofilik katalizörler. |
| BR112013015898A2 (pt) | 2010-12-22 | 2018-06-26 | Baxter International Inc. | derivado de ácido graxo solúvel em água, e, métodos para preparar um derivado de ácido graxo e uma proteína terapêutica conjugada. |
| US8785139B2 (en) | 2011-05-18 | 2014-07-22 | Baxter International Inc. | Modification-dependent activity assays |
| CN108771655A (zh) | 2011-10-28 | 2018-11-09 | 诚信生物公司 | 含有氨基酸的蛋白质制剂 |
| WO2013120497A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein |
| AU2013204754C1 (en) | 2012-05-16 | 2018-10-11 | Takeda Pharmaceutical Company Limited | Nucleophilic Catalysts for Oxime Linkage |
| US20130310546A1 (en) | 2012-05-16 | 2013-11-21 | Bater Healthcare Sa | Nucleophilic catalysts for oxime linkage and use of nmr analyses of the same |
| US20150174203A1 (en) | 2012-05-30 | 2015-06-25 | Icahn School Of Medicine At Mount Sinai | Compositions And Methods For Modulating Pro-Inflammatory Immune Response |
| CA2884455A1 (en) | 2012-09-21 | 2014-03-27 | Integragen | A new method for classification of liver samples and diagnosis of focal nodule dysplasia, hepatocellular adenoma, and hepatocellular carcinoma |
| US9206423B2 (en) * | 2012-12-30 | 2015-12-08 | The Regents Of The University Of California | Methods of modulating compliance of the trabecular meshwork |
| WO2014167529A1 (en) | 2013-04-10 | 2014-10-16 | Institut De Cardiologie De Montreal | Methods and compositions for preventing and treating atherosclerosis |
| US10011837B2 (en) * | 2014-03-04 | 2018-07-03 | Sylentis Sau | SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| CA2948871A1 (en) | 2014-05-22 | 2015-11-26 | Fred Hutchinson Cancer Research Center | Lilrb2 and notch-mediated expansion of hematopoietic precursor cells |
| MX387420B (es) | 2015-11-24 | 2025-03-18 | Commw Scient Ind Res Org | Producción de virus en cultivos celulares. |
| EP3380616A4 (en) | 2015-11-24 | 2019-11-06 | Commonwealth Scientific and Industrial Research Organisation | MANUFACTURE OF VIRUSES IN BIRDS |
| US20190177391A1 (en) | 2016-03-31 | 2019-06-13 | Baylor Research Institute | Angiopoietin-like protein 8 (angptl8) |
| SG11201901306XA (en) * | 2016-08-19 | 2019-03-28 | Toolgen Inc | Artificially engineered angiogenesis regulatory system |
| NZ750953A (en) * | 2016-08-30 | 2026-02-27 | Regeneron Pharma | Methods of treating severe insulin resistance by interfering with glucagon receptor signaling |
| US12447213B2 (en) | 2016-10-07 | 2025-10-21 | The Broad Institute, Inc. | Modulation of novel immune checkpoint targets |
| WO2018090006A1 (en) | 2016-11-14 | 2018-05-17 | Memorial Sloan-Kettering Cancer Center | Methods for drug discovery using stem cell-derived schwann cells |
| WO2018174861A1 (en) | 2017-03-21 | 2018-09-27 | Mprobe Inc. | Methods and compositions for detecting early stage breast cancer with rna-seq expression profiling |
| WO2018175630A1 (en) | 2017-03-23 | 2018-09-27 | The Regents Of The University Of California | Stimulation of hair growth by senescent cells and senescence associated secretory phenotype |
| JP2018164442A (ja) * | 2017-03-28 | 2018-10-25 | 国立大学法人 熊本大学 | 皮膚有棘細胞癌の判定、予防又は治療方法 |
| JP6779164B2 (ja) * | 2017-03-28 | 2020-11-04 | ヤンマーパワーテクノロジー株式会社 | 作業車両の自律走行システム |
| CA3065317A1 (en) | 2017-05-31 | 2018-12-06 | Commonwealth Scientific And Industrial Research Organisation | Trait selection in avians |
| WO2019140380A1 (en) | 2018-01-12 | 2019-07-18 | Kymera Therapeutics, Inc. | Protein degraders and uses thereof |
| CN111867614A (zh) | 2018-01-18 | 2020-10-30 | 艾达奈特公司 | 抗lilrb抗体及其用途 |
| GB201806118D0 (en) | 2018-04-13 | 2018-05-30 | Univ Edinburgh | Macrophage use |
| MX2021008797A (es) | 2019-01-23 | 2022-01-31 | Regeneron Pharma | Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7). |
| JP2022535717A (ja) | 2019-05-24 | 2022-08-10 | エンピリコ インク． | アンジオポエチン様７（ａｎｇｐｔｌ７）関連疾患の処置 |
| US20230357774A1 (en) | 2020-09-29 | 2023-11-09 | Empirico Inc. | Compositions and methods for the treatment of angiopoietin like 7 (angptl7) related diseases |
-
2020
- 2020-01-21 MX MX2021008797A patent/MX2021008797A/es unknown
- 2020-01-21 EP EP20705596.3A patent/EP3914711A2/en active Pending
- 2020-01-21 CA CA3126476A patent/CA3126476A1/en active Pending
- 2020-01-21 KR KR1020217026590A patent/KR20210132045A/ko active Pending
- 2020-01-21 US US16/748,006 patent/US11767526B2/en active Active
- 2020-01-21 SG SG11202107497XA patent/SG11202107497XA/en unknown
- 2020-01-21 CN CN202080022870.2A patent/CN113646432A/zh active Pending
- 2020-01-21 AU AU2020210630A patent/AU2020210630C1/en active Active
- 2020-01-21 IL IL284700A patent/IL284700B2/en unknown
- 2020-01-21 JP JP2021543226A patent/JP2022523301A/ja active Pending
- 2020-01-21 WO PCT/US2020/014373 patent/WO2020154268A2/en not_active Ceased
-
2021
- 2021-05-12 US US17/318,023 patent/US11512309B2/en active Active
-
2024
- 2024-12-06 JP JP2024213170A patent/JP2025023307A/ja active Pending
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