JP2022520437A5 - - Google Patents
Info
- Publication number
- JP2022520437A5 JP2022520437A5 JP2021547404A JP2021547404A JP2022520437A5 JP 2022520437 A5 JP2022520437 A5 JP 2022520437A5 JP 2021547404 A JP2021547404 A JP 2021547404A JP 2021547404 A JP2021547404 A JP 2021547404A JP 2022520437 A5 JP2022520437 A5 JP 2022520437A5
- Authority
- JP
- Japan
- Prior art keywords
- expression construct
- seq
- artificial expression
- construct according
- aav
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024220548A JP7909577B2 (ja) | 2019-02-15 | 2024-12-17 | 選択されたニューロン細胞集団における遺伝子発現を選択的に調節するための人工発現コンストラクト |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962806686P | 2019-02-15 | 2019-02-15 | |
| US201962806660P | 2019-02-15 | 2019-02-15 | |
| US62/806,686 | 2019-02-15 | ||
| US62/806,660 | 2019-02-15 | ||
| US201962874859P | 2019-07-16 | 2019-07-16 | |
| US62/874,859 | 2019-07-16 | ||
| PCT/US2020/018416 WO2020168279A2 (en) | 2019-02-15 | 2020-02-14 | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024220548A Division JP7909577B2 (ja) | 2019-02-15 | 2024-12-17 | 選択されたニューロン細胞集団における遺伝子発現を選択的に調節するための人工発現コンストラクト |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022520437A JP2022520437A (ja) | 2022-03-30 |
| JP2022520437A5 true JP2022520437A5 (enExample) | 2022-12-28 |
| JP7608348B2 JP7608348B2 (ja) | 2025-01-06 |
Family
ID=72044145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021547404A Active JP7608348B2 (ja) | 2019-02-15 | 2020-02-14 | 選択されたニューロン細胞集団における遺伝子発現を選択的に調節するための人工発現コンストラクト |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12702722B2 (enExample) |
| EP (1) | EP3923995A4 (enExample) |
| JP (1) | JP7608348B2 (enExample) |
| AU (1) | AU2020223367B2 (enExample) |
| CA (1) | CA3142948A1 (enExample) |
| WO (1) | WO2020168279A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7590962B2 (ja) | 2018-11-05 | 2024-11-27 | アレン インスティテュート | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| CA3142948A1 (en) | 2019-02-15 | 2020-08-20 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
| JP7721568B2 (ja) * | 2020-04-21 | 2025-08-12 | アレン インスティテュート | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
| EP4244366A4 (en) * | 2020-11-10 | 2024-12-25 | Allen Institute | Artificial expression constructs for modulating gene expression in chandelier cells |
| US20240182923A1 (en) * | 2021-03-30 | 2024-06-06 | Allen Institute | Artificial expression constructs for modulating gene expression in claustrum neurons |
| AU2022276538A1 (en) * | 2021-05-21 | 2023-11-09 | Allen Institute | Artificial expression constructs for modulating gene expression in neurons within the thalamus |
| CA3233342A1 (en) * | 2021-10-05 | 2023-04-13 | Tanya DAIGLE | Artificial expression constructs for modulating gene expression in the cerebellum and a secondary cell type |
| EP4735613A1 (en) * | 2023-06-28 | 2026-05-06 | Allen Institute | Artificial expression constructs for modulating gene expression in cardiomyocytes |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69918090T2 (de) * | 1998-04-24 | 2005-06-16 | University Of Florida, Gainesville | Rekombinanter adeno-assoziierter viraler vektor, der alpha-1 antitrypsin kodiert, zur gentherapie |
| US20070037165A1 (en) | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| EP2028268A1 (en) | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| EP3702460A1 (en) * | 2010-11-12 | 2020-09-02 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| US9284575B2 (en) * | 2012-03-06 | 2016-03-15 | Duke University | Synthetic regulation of gene expression |
| WO2013155222A2 (en) | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| US9579399B2 (en) | 2012-08-27 | 2017-02-28 | Friedrich Miescher Institute For Biomedical Research | Retinal OFF circuit-specific promoter |
| EP2922972B1 (en) | 2012-11-26 | 2017-04-26 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Colorectal cancer classification with differential prognosis and personalized therapeutic responses |
| US20150376612A1 (en) | 2014-06-10 | 2015-12-31 | The General Hospital Corporation | CCCTC-Binding Factor (CTCF) RNA Interactome |
| CL2014003590A1 (es) | 2014-12-30 | 2015-07-10 | Univ Chile | Virus aav/xbp1s-ha, método de tratamiento genético y su uso en la optimizacion y mejoramiento de las capacidades cognitivas, de memoria y de aprendizaje. |
| US10682424B2 (en) | 2015-03-31 | 2020-06-16 | New York University | Compositions and method for reducing seizures |
| US9790490B2 (en) * | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| AU2016366549B2 (en) * | 2015-12-11 | 2022-11-10 | California Institute Of Technology | Targeting peptides for directing adeno-associated viruses (AAVs) |
| EP3416663B1 (en) * | 2016-02-18 | 2021-04-14 | The Penn State Research Foundation | Generating gabaergic neurons in brains |
| CN117821509A (zh) | 2017-04-03 | 2024-04-05 | 编码治疗公司 | 组织选择性转基因表达 |
| JP7590962B2 (ja) * | 2018-11-05 | 2024-11-27 | アレン インスティテュート | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| CA3142948A1 (en) | 2019-02-15 | 2020-08-20 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
-
2020
- 2020-02-14 CA CA3142948A patent/CA3142948A1/en active Pending
- 2020-02-14 US US17/431,079 patent/US12702722B2/en active Active
- 2020-02-14 EP EP20756018.6A patent/EP3923995A4/en active Pending
- 2020-02-14 JP JP2021547404A patent/JP7608348B2/ja active Active
- 2020-02-14 AU AU2020223367A patent/AU2020223367B2/en active Active
- 2020-02-14 WO PCT/US2020/018416 patent/WO2020168279A2/en not_active Ceased
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