JP2023522708A5 - - Google Patents
Info
- Publication number
- JP2023522708A5 JP2023522708A5 JP2022563930A JP2022563930A JP2023522708A5 JP 2023522708 A5 JP2023522708 A5 JP 2023522708A5 JP 2022563930 A JP2022563930 A JP 2022563930A JP 2022563930 A JP2022563930 A JP 2022563930A JP 2023522708 A5 JP2023522708 A5 JP 2023522708A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- sequence number
- sequences
- copies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025127056A JP2025163106A (ja) | 2020-04-21 | 2025-07-30 | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063013342P | 2020-04-21 | 2020-04-21 | |
| US63/013,342 | 2020-04-21 | ||
| PCT/US2021/028489 WO2021216778A2 (en) | 2020-04-21 | 2021-04-21 | Artificial expression constructs for selectively modulating gene expression in neocortical layer 5 glutamatergic neurons |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025127056A Division JP2025163106A (ja) | 2020-04-21 | 2025-07-30 | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522708A JP2023522708A (ja) | 2023-05-31 |
| JP2023522708A5 true JP2023522708A5 (enExample) | 2024-02-27 |
| JP7721568B2 JP7721568B2 (ja) | 2025-08-12 |
Family
ID=78269916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022563930A Active JP7721568B2 (ja) | 2020-04-21 | 2021-04-21 | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
| JP2025127056A Pending JP2025163106A (ja) | 2020-04-21 | 2025-07-30 | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025127056A Pending JP2025163106A (ja) | 2020-04-21 | 2025-07-30 | 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230159952A1 (enExample) |
| EP (1) | EP4139462A4 (enExample) |
| JP (2) | JP7721568B2 (enExample) |
| KR (1) | KR20230002788A (enExample) |
| AU (1) | AU2021261359A1 (enExample) |
| CA (1) | CA3175993A1 (enExample) |
| WO (1) | WO2021216778A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3233342A1 (en) * | 2021-10-05 | 2023-04-13 | Tanya DAIGLE | Artificial expression constructs for modulating gene expression in the cerebellum and a secondary cell type |
| EP4507785A4 (en) * | 2022-04-11 | 2026-06-03 | Broad Inst Inc | Activators for directed gene expression in neural cell populations, compositions and associated processes |
| EP4536835A2 (en) * | 2022-06-13 | 2025-04-16 | Allen Institute | Artificial expression constructs for modulating gene expression in non-neuronal central nervous system cells |
| AU2024342927A1 (en) * | 2023-09-14 | 2026-04-09 | Allen Institute | Artificial expression constructs for modulating gene expression in the basal ganglia |
| WO2025179180A1 (en) * | 2024-02-23 | 2025-08-28 | Allen Institute | Artificial expression constructs for modulating gene expression in motor neurons and cerebellar neurons |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9920317B2 (en) * | 2010-11-12 | 2018-03-20 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
| EP3416663B1 (en) * | 2016-02-18 | 2021-04-14 | The Penn State Research Foundation | Generating gabaergic neurons in brains |
| US12467064B2 (en) * | 2018-10-08 | 2025-11-11 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in interneurons |
| CN120349985A (zh) * | 2018-10-12 | 2025-07-22 | 建新公司 | 通过肝导向基因替代疗法治疗严重pku的改良的人pah的产生 |
| CA3142948A1 (en) * | 2019-02-15 | 2020-08-20 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
-
2021
- 2021-04-21 JP JP2022563930A patent/JP7721568B2/ja active Active
- 2021-04-21 US US17/996,910 patent/US20230159952A1/en active Pending
- 2021-04-21 EP EP21793682.2A patent/EP4139462A4/en active Pending
- 2021-04-21 KR KR1020227040046A patent/KR20230002788A/ko active Pending
- 2021-04-21 WO PCT/US2021/028489 patent/WO2021216778A2/en not_active Ceased
- 2021-04-21 CA CA3175993A patent/CA3175993A1/en active Pending
- 2021-04-21 AU AU2021261359A patent/AU2021261359A1/en active Pending
-
2025
- 2025-07-30 JP JP2025127056A patent/JP2025163106A/ja active Pending
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