JP2022514704A5 - - Google Patents
Info
- Publication number
- JP2022514704A5 JP2022514704A5 JP2021536212A JP2021536212A JP2022514704A5 JP 2022514704 A5 JP2022514704 A5 JP 2022514704A5 JP 2021536212 A JP2021536212 A JP 2021536212A JP 2021536212 A JP2021536212 A JP 2021536212A JP 2022514704 A5 JP2022514704 A5 JP 2022514704A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- comp
- fusion protein
- glycosylated
- tag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024214739A JP2025032259A (ja) | 2018-12-21 | 2024-12-09 | Ｏ結合型グリコシル化認識モチーフ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783971P | 2018-12-21 | 2018-12-21 | |
| US62/783,971 | 2018-12-21 | ||
| PCT/US2019/059893 WO2020131236A1 (en) | 2018-12-21 | 2019-11-05 | O-linked glycosylation recognition motifs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024214739A Division JP2025032259A (ja) | 2018-12-21 | 2024-12-09 | Ｏ結合型グリコシル化認識モチーフ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022514704A JP2022514704A (ja) | 2022-02-14 |
| JP2022514704A5 true JP2022514704A5 (enExample) | 2022-11-11 |
| JP7699543B2 JP7699543B2 (ja) | 2025-06-27 |
Family
ID=71101542
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536212A Active JP7699543B2 (ja) | 2018-12-21 | 2019-11-05 | Ｏ結合型グリコシル化認識モチーフ |
| JP2024214739A Withdrawn JP2025032259A (ja) | 2018-12-21 | 2024-12-09 | Ｏ結合型グリコシル化認識モチーフ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024214739A Withdrawn JP2025032259A (ja) | 2018-12-21 | 2024-12-09 | Ｏ結合型グリコシル化認識モチーフ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12350342B2 (enExample) |
| EP (1) | EP3897685B1 (enExample) |
| JP (2) | JP7699543B2 (enExample) |
| AU (1) | AU2019404924B2 (enExample) |
| CA (1) | CA3124312A1 (enExample) |
| ES (1) | ES3055827T3 (enExample) |
| WO (1) | WO2020131236A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3039659T3 (en) | 2015-02-26 | 2025-10-23 | Vaxnewmo Llc | Acinetobacter o-oligosaccharyltransferases and uses thereof |
| JP2021528059A (ja) | 2018-06-16 | 2021-10-21 | ヴァックスニューモ エルエルシーＶａｘｎｅｗｍｏ Ｌｌｃ | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
| US12350342B2 (en) | 2018-12-21 | 2025-07-08 | Vaxnewmo Llc | O-linked glycosylation recognition motifs |
| US20240066109A1 (en) * | 2020-12-31 | 2024-02-29 | Vaxnewmo Llc | Klebsiella Pneumoniae O-Antigen Glycosylated Proteins and Methods of Making and Uses Thereof |
| EP4329796A4 (en) * | 2021-04-28 | 2025-03-19 | Vaxnewmo Llc | Minimal sequons sufficient for o-linking glycosylation |
| CN115120712B (zh) * | 2022-06-30 | 2025-11-18 | 中国人民解放军军事科学院军事医学研究院 | 肺炎链球菌糖蛋白生物结合疫苗及其制备方法和应用 |
| WO2024077205A2 (en) * | 2022-10-07 | 2024-04-11 | Vaxnewmo Llc | Moraxellaceae o-linking oligosaccharyltransferases, glycosylation fragments, and uses thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| CA2671709C (en) | 2006-12-13 | 2016-08-16 | The Governors Of The University Of Alberta | Methods and systems for o-glycosylating proteins |
| US20130196410A1 (en) * | 2010-03-05 | 2013-08-01 | Alnylam Pharmaceuticals, Inc | Compositions and methods for modifying the glycosylation pattern of a polypeptide |
| CA2844831A1 (en) | 2011-08-12 | 2013-02-21 | The Governors Of The University Of Alberta | Method of diagnosing bacterial infections using bacterial glycoproteins |
| WO2013067523A1 (en) | 2011-11-04 | 2013-05-10 | Cornell University | A prokaryote-based cell-free system for the synthesis of glycoproteins |
| ES2905107T3 (es) | 2012-10-12 | 2022-04-07 | Glaxosmithkline Biologicals Sa | Procedimientos de modificación de células hospedadoras |
| EP3508579B1 (en) | 2012-11-07 | 2021-06-30 | GlaxoSmithKline Biologicals SA | Production of recombinant vaccine in e. coli by enzymatic conjugation |
| US9499614B2 (en) * | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
| JP6356229B2 (ja) | 2013-06-04 | 2018-07-11 | アイコン ジェネティクス ゲーエムベーハー | 植物産生糖タンパク質及び組換え糖タンパク質のｎ−グリコシル化部位占有率を調節する方法 |
| US9988426B2 (en) | 2014-09-18 | 2018-06-05 | University Of Maryland, Baltimore | Broad spectrum conjugate vaccine to prevent Klebsiella pneumoniae and Pseudomonas aeruginosa infections |
| CN107614679B (zh) * | 2014-12-30 | 2026-04-07 | 葛兰素史密丝克莱恩生物有限公司 | 用于蛋白糖基化的组合物和方法 |
| ES3039659T3 (en) | 2015-02-26 | 2025-10-23 | Vaxnewmo Llc | Acinetobacter o-oligosaccharyltransferases and uses thereof |
| WO2018135860A1 (ko) * | 2017-01-17 | 2018-07-26 | 포항공과대학교 산학협력단 | 식물 세포에서의 목적 단백질 발현을 위한 재조합 벡터 |
| EP3492481A1 (en) | 2017-11-30 | 2019-06-05 | Vaxxilon AG | Vaccine against klebsiella pneumoniae |
| JP2021528059A (ja) | 2018-06-16 | 2021-10-21 | ヴァックスニューモ エルエルシーＶａｘｎｅｗｍｏ Ｌｌｃ | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
| CN113227125A (zh) | 2018-12-12 | 2021-08-06 | 葛兰素史密丝克莱恩生物有限公司 | 用于o-连接的糖基化的修饰的载体蛋白 |
| US12350342B2 (en) | 2018-12-21 | 2025-07-08 | Vaxnewmo Llc | O-linked glycosylation recognition motifs |
-
2019
- 2019-11-05 US US17/416,106 patent/US12350342B2/en active Active
- 2019-11-05 ES ES19898969T patent/ES3055827T3/es active Active
- 2019-11-05 AU AU2019404924A patent/AU2019404924B2/en active Active
- 2019-11-05 CA CA3124312A patent/CA3124312A1/en active Pending
- 2019-11-05 WO PCT/US2019/059893 patent/WO2020131236A1/en not_active Ceased
- 2019-11-05 JP JP2021536212A patent/JP7699543B2/ja active Active
- 2019-11-05 EP EP19898969.1A patent/EP3897685B1/en active Active
-
2024
- 2024-12-09 JP JP2024214739A patent/JP2025032259A/ja not_active Withdrawn
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