JP2021528059A5 - - Google Patents

Info

Publication number
JP2021528059A5
JP2021528059A5 JP2020569986A JP2020569986A JP2021528059A5 JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5 JP 2020569986 A JP2020569986 A JP 2020569986A JP 2020569986 A JP2020569986 A JP 2020569986A JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5
Authority
JP
Japan
Prior art keywords
protein
comp
glycosylated
polysaccharide
tag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020569986A
Other languages
English (en)
Japanese (ja)
Other versions
JP7892938B2 (ja
JP2021528059A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/037251 external-priority patent/WO2019241672A2/en
Publication of JP2021528059A publication Critical patent/JP2021528059A/ja
Publication of JP2021528059A5 publication Critical patent/JP2021528059A5/ja
Priority to JP2024061674A priority Critical patent/JP2024079845A/ja
Application granted granted Critical
Publication of JP7892938B2 publication Critical patent/JP7892938B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020569986A 2018-06-16 2019-06-14 グリコシル化されたComPピリンバリアント、製造方法及びその使用 Active JP7892938B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024061674A JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862685970P 2018-06-16 2018-06-16
US62/685,970 2018-06-16
US201862783971P 2018-12-21 2018-12-21
US62/783,971 2018-12-21
PCT/US2019/037251 WO2019241672A2 (en) 2018-06-16 2019-06-14 Glycosylated comp pilin variants, methods of making and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024061674A Division JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Publications (3)

Publication Number Publication Date
JP2021528059A JP2021528059A (ja) 2021-10-21
JP2021528059A5 true JP2021528059A5 (enExample) 2022-06-22
JP7892938B2 JP7892938B2 (ja) 2026-07-22

Family

ID=68843212

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020569986A Active JP7892938B2 (ja) 2018-06-16 2019-06-14 グリコシル化されたComPピリンバリアント、製造方法及びその使用
JP2024061674A Withdrawn JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024061674A Withdrawn JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Country Status (7)

Country Link
US (2) US11932670B2 (enExample)
EP (1) EP3806881B1 (enExample)
JP (2) JP7892938B2 (enExample)
AU (1) AU2019287659B2 (enExample)
CA (1) CA3103474A1 (enExample)
ES (1) ES3051337T3 (enExample)
WO (1) WO2019241672A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
ES3051337T3 (en) 2018-06-16 2025-12-26 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs
US20230226175A1 (en) 2020-06-25 2023-07-20 Glaxosmithkline Biologicals Sa Modified exotoxin a proteins
EP4271417A4 (en) * 2020-12-31 2024-11-27 Vaxnewmo Llc GLYCOSYLATED KLEBSIELLA PNEUMONIAE O-ANTIGEN AND METHODS OF PREPARATION AND USES THEREOF
JP2024517754A (ja) * 2021-04-28 2024-04-23 ヴァックスニューモ エルエルシー O-結合型グリコシル化に十分な最小シークオン

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9238830B2 (en) 2006-12-13 2016-01-19 The Governors Of The University Of Alberta Methods and systems for O-glycosylating proteins
US20130196410A1 (en) 2010-03-05 2013-08-01 Alnylam Pharmaceuticals, Inc Compositions and methods for modifying the glycosylation pattern of a polypeptide
EP2742355B1 (en) 2011-08-12 2018-12-19 The Governors of the University of Alberta Method of diagnosing bacterial infections using bacterial glycoproteins
IN2014CN04076A (enExample) 2011-11-04 2015-10-23 Univ Cornell
KR20150068998A (ko) 2012-10-12 2015-06-22 글리코박신 아게 숙주 세포 변형 방법
EP2917351B1 (en) * 2012-11-07 2018-12-19 GlaxoSmithKline Biologicals S.A. Production of recombinant vaccine in e. coli by enzymatic conjugation
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
JP6356229B2 (ja) 2013-06-04 2018-07-11 アイコン ジェネティクス ゲーエムベーハー 植物産生糖タンパク質及び組換え糖タンパク質のn−グリコシル化部位占有率を調節する方法
US9988426B2 (en) 2014-09-18 2018-06-05 University Of Maryland, Baltimore Broad spectrum conjugate vaccine to prevent Klebsiella pneumoniae and Pseudomonas aeruginosa infections
SI3240895T1 (sl) 2014-12-30 2022-04-29 Glaxosmithkline Biologicals S.A. Sestavki in postopki za glikozilacijo proteinov
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
US11279943B2 (en) 2017-01-17 2022-03-22 Bioapplications Inc. Recombinant vector for expressing target protein in plant cell
EP3492481A1 (en) 2017-11-30 2019-06-05 Vaxxilon AG Vaccine against klebsiella pneumoniae
ES3051337T3 (en) 2018-06-16 2025-12-26 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
JP7551618B2 (ja) 2018-12-12 2024-09-17 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム O-結合型グリコシル化のための修飾キャリアタンパク質
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs

Similar Documents

Publication Publication Date Title
JP7851988B2 (ja) 非天然アミノ酸とのポリペプチド抗原接合体
JP2022514704A5 (enExample)
CN116209753A (zh) 肺炎克雷伯氏菌o-抗原疫苗
JP7630603B2 (ja) 出現血清型24fを含む多価肺炎球菌複合糖質ワクチン
HRP20240847T1 (hr) Novi polisaharid i njegove upotrebe
JP7699543B2 (ja) O結合型グリコシル化認識モチーフ
JP2023531242A5 (enExample)
US12290563B2 (en) Production of E. coli 018 bioconjugates
CN113164581A (zh) 纯化的肺炎链球菌荚膜多糖
CN102695791A (zh) 蛋白质糖基化
CN115803087A (zh) 多价疫苗组合物及其用途
JP5744842B2 (ja) 髄膜炎菌と肺炎球菌との結合型ワクチン及びそれを使用する方法
JP7645946B2 (ja) 肺炎球菌表面タンパク質A(PspA)の発現
CN111741765A (zh) 免疫原性组合物
US11097000B2 (en) Klebsiella pneumoniae capsule polysaccharide vaccines
JP2024517754A5 (enExample)
CN115362177A (zh) 糖类的纯化
HUP0700044A2 (en) Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates
CN120897997A (zh) 用于生产具有与第二多肽配偶体的异肽键的糖缀合物多肽的组合物和方法以及这些糖缀合物多肽的用途