JP2021528059A5 - - Google Patents

Info

Publication number
JP2021528059A5
JP2021528059A5 JP2020569986A JP2020569986A JP2021528059A5 JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5 JP 2020569986 A JP2020569986 A JP 2020569986A JP 2020569986 A JP2020569986 A JP 2020569986A JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5
Authority
JP
Japan
Prior art keywords
protein
comp
glycosylated
polysaccharide
tag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020569986A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021528059A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/037251 external-priority patent/WO2019241672A2/en
Publication of JP2021528059A publication Critical patent/JP2021528059A/ja
Publication of JP2021528059A5 publication Critical patent/JP2021528059A5/ja
Priority to JP2024061674A priority Critical patent/JP2024079845A/ja
Pending legal-status Critical Current

Links

JP2020569986A 2018-06-16 2019-06-14 グリコシル化されたComPピリンバリアント、製造方法及びその使用 Pending JP2021528059A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024061674A JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862685970P 2018-06-16 2018-06-16
US62/685,970 2018-06-16
US201862783971P 2018-12-21 2018-12-21
US62/783,971 2018-12-21
PCT/US2019/037251 WO2019241672A2 (en) 2018-06-16 2019-06-14 Glycosylated comp pilin variants, methods of making and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024061674A Division JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Publications (2)

Publication Number Publication Date
JP2021528059A JP2021528059A (ja) 2021-10-21
JP2021528059A5 true JP2021528059A5 (enExample) 2022-06-22

Family

ID=68843212

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020569986A Pending JP2021528059A (ja) 2018-06-16 2019-06-14 グリコシル化されたComPピリンバリアント、製造方法及びその使用
JP2024061674A Pending JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024061674A Pending JP2024079845A (ja) 2018-06-16 2024-04-05 グリコシル化されたComPピリンバリアント、製造方法及びその使用

Country Status (7)

Country Link
US (2) US11932670B2 (enExample)
EP (1) EP3806881B1 (enExample)
JP (2) JP2021528059A (enExample)
AU (1) AU2019287659B2 (enExample)
CA (1) CA3103474A1 (enExample)
ES (1) ES3051337T3 (enExample)
WO (1) WO2019241672A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CA3103474A1 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
WO2020131236A1 (en) * 2018-12-21 2020-06-25 Vaxnewmo Llc O-linked glycosylation recognition motifs
BR112022023234A2 (pt) * 2020-06-25 2023-01-03 Glaxosmithkline Biologicals Sa Proteínas de exotoxina a modificada
WO2022147142A1 (en) * 2020-12-31 2022-07-07 Vaxnewmo Llc Klebsiella pneumoniae o-antigen glycosylated proteins and methods of making and uses thereof
WO2022232256A1 (en) * 2021-04-28 2022-11-03 Vaxnewmo Llc Minimal sequons sufficient for o-linking glycosylation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515430A (ja) 2006-12-13 2010-05-13 ザ・ガバナーズ・オブ・ザ・ユニバーシティ・オブ・アルバータ タンパク質のo−グリコシル化方法およびそのシステム
WO2011109600A1 (en) 2010-03-05 2011-09-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for modifying the glycosylation pattern of a polypeptide
CA2844831A1 (en) 2011-08-12 2013-02-21 The Governors Of The University Of Alberta Method of diagnosing bacterial infections using bacterial glycoproteins
HK1202896A1 (en) 2011-11-04 2015-10-09 康奈尔大学 A prokaryote-based cell-free system for the synthesis of glycoproteins
ES2905107T3 (es) 2012-10-12 2022-04-07 Glaxosmithkline Biologicals Sa Procedimientos de modificación de células hospedadoras
EP3444352B1 (en) * 2012-11-07 2020-12-16 GlaxoSmithKline Biologicals SA Production of recombinant vaccine in e. coli by enzymatic conjugation
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
JP6356229B2 (ja) 2013-06-04 2018-07-11 アイコン ジェネティクス ゲーエムベーハー 植物産生糖タンパク質及び組換え糖タンパク質のn−グリコシル化部位占有率を調節する方法
EP3193918A4 (en) 2014-09-18 2018-06-20 University of Maryland, Baltimore Broad spectrum conjugate vaccine to prevent klebsiella pneumoniae and pseudomonas aeruginosa infections
DK3240895T3 (da) 2014-12-30 2022-04-11 Glaxosmithkline Biologicals Sa Sammensætninger og fremgangsmåder til proteinglykosylering
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
JP6968451B2 (ja) 2017-01-17 2021-11-17 バイオアプリケーションズ インコーポレイテッドBioapplications Inc. 植物細胞における目的タンパク質の発現のための組換えベクター
EP3492481A1 (en) 2017-11-30 2019-06-05 Vaxxilon AG Vaccine against klebsiella pneumoniae
CA3103474A1 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
US20220054632A1 (en) 2018-12-12 2022-02-24 Glaxosmithkline Biologicals Sa Modified carrier proteins for o-linked glycosylation
WO2020131236A1 (en) 2018-12-21 2020-06-25 Vaxnewmo Llc O-linked glycosylation recognition motifs

Similar Documents

Publication Publication Date Title
JP7851988B2 (ja) 非天然アミノ酸とのポリペプチド抗原接合体
JP2022514704A5 (enExample)
CN116209753A (zh) 肺炎克雷伯氏菌o-抗原疫苗
HRP20240847T1 (hr) Novi polisaharid i njegove upotrebe
JP7699543B2 (ja) O結合型グリコシル化認識モチーフ
JP7630603B2 (ja) 出現血清型24fを含む多価肺炎球菌複合糖質ワクチン
JP2023531242A5 (enExample)
US12290563B2 (en) Production of E. coli 018 bioconjugates
CN102695791A (zh) 蛋白质糖基化
CN113164581A (zh) 纯化的肺炎链球菌荚膜多糖
CN115803087A (zh) 多价疫苗组合物及其用途
JP5744842B2 (ja) 髄膜炎菌と肺炎球菌との結合型ワクチン及びそれを使用する方法
JP7645946B2 (ja) 肺炎球菌表面タンパク質A(PspA)の発現
CN111741765A (zh) 免疫原性组合物
JP2024517754A5 (enExample)
US11097000B2 (en) Klebsiella pneumoniae capsule polysaccharide vaccines
CN115362177A (zh) 糖类的纯化
HUP0700044A2 (en) Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates
CN120897997A (zh) 用于生产具有与第二多肽配偶体的异肽键的糖缀合物多肽的组合物和方法以及这些糖缀合物多肽的用途