JP2022509445A5 - - Google Patents

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Publication number
JP2022509445A5
JP2022509445A5 JP2021547960A JP2021547960A JP2022509445A5 JP 2022509445 A5 JP2022509445 A5 JP 2022509445A5 JP 2021547960 A JP2021547960 A JP 2021547960A JP 2021547960 A JP2021547960 A JP 2021547960A JP 2022509445 A5 JP2022509445 A5 JP 2022509445A5
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JP
Japan
Prior art keywords
polypeptide
composition according
pharmaceutical composition
fibrosis
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021547960A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022509445A (ja
JP7659499B2 (ja
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Priority claimed from KR1020180128033A external-priority patent/KR102129178B1/ko
Priority claimed from KR1020180128204A external-priority patent/KR102129179B1/ko
Priority claimed from KR1020180128625A external-priority patent/KR102161892B1/ko
Application filed filed Critical
Priority claimed from PCT/IB2019/001136 external-priority patent/WO2020084344A2/en
Publication of JP2022509445A publication Critical patent/JP2022509445A/ja
Publication of JP2022509445A5 publication Critical patent/JP2022509445A5/ja
Priority to JP2024092192A priority Critical patent/JP2024133483A/ja
Application granted granted Critical
Publication of JP7659499B2 publication Critical patent/JP7659499B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021547960A 2018-10-25 2019-10-24 線維症を治療又は予防するための組成物及び方法 Active JP7659499B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024092192A JP2024133483A (ja) 2018-10-25 2024-06-06 線維症を治療又は予防するための組成物及び方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
KR10-2018-0128204 2018-10-25
KR10-2018-0128033 2018-10-25
KR1020180128033A KR102129178B1 (ko) 2018-10-25 2018-10-25 심근경색 예방 또는 치료용 재조합 단백질을 포함하는 심근경색 예방 또는 치료용 조성물
KR1020180128204A KR102129179B1 (ko) 2018-10-25 2018-10-25 알츠하이머병 예방 또는 치료용 재조합 단백질을 포함하는 알츠하이머병 예방 또는 치료용 조성물
KR1020180128625A KR102161892B1 (ko) 2018-10-26 2018-10-26 특발성 폐섬유증 예방 또는 치료용 재조합 단백질을 포함하는 특발성 폐섬유증 예방 또는 치료용 조성물
KR10-2018-0128625 2018-10-26
PCT/IB2019/001136 WO2020084344A2 (en) 2018-10-25 2019-10-24 Compositions and methods for treating or preventing fibrosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024092192A Division JP2024133483A (ja) 2018-10-25 2024-06-06 線維症を治療又は予防するための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2022509445A JP2022509445A (ja) 2022-01-20
JP2022509445A5 true JP2022509445A5 (https=) 2022-10-27
JP7659499B2 JP7659499B2 (ja) 2025-04-09

Family

ID=70331794

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021547960A Active JP7659499B2 (ja) 2018-10-25 2019-10-24 線維症を治療又は予防するための組成物及び方法
JP2024092192A Withdrawn JP2024133483A (ja) 2018-10-25 2024-06-06 線維症を治療又は予防するための組成物及び方法

Family Applications After (1)

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JP2024092192A Withdrawn JP2024133483A (ja) 2018-10-25 2024-06-06 線維症を治療又は予防するための組成物及び方法

Country Status (5)

Country Link
US (2) US12139518B2 (https=)
EP (1) EP3870210A4 (https=)
JP (2) JP7659499B2 (https=)
CN (1) CN113301914B (https=)
WO (1) WO2020084344A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7659499B2 (ja) * 2018-10-25 2025-04-09 ネクセル カンパニー,リミテッド 線維症を治療又は予防するための組成物及び方法
MX2022002638A (es) 2019-09-06 2022-03-25 Novartis Ag Proteinas de fusion terapeuticas.
KR102801198B1 (ko) * 2021-06-28 2025-04-30 (주) 넥셀 특발성 폐섬유증 예방 또는 치료용 폴리펩타이드 및 이를 포함하는 약학 조성물
KR102758046B1 (ko) * 2021-11-05 2025-01-23 (주) 넥셀 궤양성 대장염 예방 또는 치료용 재조합 단백질 및 이를 포함하는 궤양성 대장염 예방 또는 치료용 조성물
CN118633748A (zh) * 2024-05-29 2024-09-13 哈尔滨工业大学 一种包含乳源mfg-e8的产品及其在改善衰老、学习和/或记忆障碍中的应用

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Publication number Priority date Publication date Assignee Title
US5972337A (en) 1990-11-01 1999-10-26 Cancer Research Fund Of Contra Costa 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
EP1004664A1 (en) 1998-11-24 2000-05-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Compositions and methods using lactadherin or variants thereof
IL160142A0 (en) * 2001-08-17 2004-06-20 Anosys Inc Methods and compounds for the targeting of protein to exosomes
JP4160292B2 (ja) * 2001-11-20 2008-10-01 独立行政法人科学技術振興機構 生体内のアポトーシス細胞の除去促進剤及び除去阻害剤
WO2010096713A2 (en) * 2009-02-20 2010-08-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for the diagnosis of age-associated vascular disorders
JP2014507649A (ja) * 2011-01-18 2014-03-27 バクスター・インターナショナル・インコーポレイテッド ヒト血液中の抗βアミロイド抗体の測定
EP3021942A4 (en) * 2013-07-19 2017-04-19 The Regents of The University of California Milk fat globule epidermal growth factor 8 regulates fatty acid uptake
WO2015025956A1 (ja) 2013-08-22 2015-02-26 国立大学法人九州大学 心筋障害治療用薬剤組成物、心筋障害予防用薬剤組成物、心不全治療用薬剤組成物、心不全予防用薬剤組成物、心筋障害又は心不全を治療又は予防する方法、mfg-e8、mfg-e8の使用、及び心筋障害又は心不全を治療又は予防する化合物のスクリーニング方法
AU2016260190A1 (en) 2015-05-12 2017-11-23 The Regents Of The University Of California Peptide treatment for inflammation and fibrosis
KR20170013621A (ko) * 2015-07-28 2017-02-07 (주) 넥셀 Milk fat globule-EGF factor(MFG-E8)을 이용한 조직섬유화 예방 또는 치료용 조성물
CN105288592A (zh) 2015-11-02 2016-02-03 哈尔滨博翱生物医药技术开发有限公司 成纤维细胞生长因子-21成熟肽在制备肝纤维化治疗药物中的应用
GB2552473A (en) * 2016-07-21 2018-01-31 Evox Therapeutics Ltd Surface decoration of extracellular vesicles
KR102129178B1 (ko) 2018-10-25 2020-07-01 (주) 넥셀 심근경색 예방 또는 치료용 재조합 단백질을 포함하는 심근경색 예방 또는 치료용 조성물
KR102129179B1 (ko) 2018-10-25 2020-07-01 (주) 넥셀 알츠하이머병 예방 또는 치료용 재조합 단백질을 포함하는 알츠하이머병 예방 또는 치료용 조성물
KR101947902B1 (ko) 2017-05-17 2019-02-13 (주) 넥셀 간 섬유화 예방 또는 치료용 재조합 단백질 및 이를 포함하는 간 섬유화 예방 또는 치료용 조성물
KR102161892B1 (ko) 2018-10-26 2020-10-05 (주) 넥셀 특발성 폐섬유증 예방 또는 치료용 재조합 단백질을 포함하는 특발성 폐섬유증 예방 또는 치료용 조성물
JP7659499B2 (ja) 2018-10-25 2025-04-09 ネクセル カンパニー,リミテッド 線維症を治療又は予防するための組成物及び方法
MX2022002638A (es) * 2019-09-06 2022-03-25 Novartis Ag Proteinas de fusion terapeuticas.
CN118076371A (zh) 2021-04-22 2024-05-24 百进生物科技公司 用于检测和耗竭磷脂酰丝氨酸阳性细胞的磷脂酰丝氨酸结合剂
KR102758046B1 (ko) 2021-11-05 2025-01-23 (주) 넥셀 궤양성 대장염 예방 또는 치료용 재조합 단백질 및 이를 포함하는 궤양성 대장염 예방 또는 치료용 조성물

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