JP2022507828A5 - - Google Patents

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Publication number
JP2022507828A5
JP2022507828A5 JP2021527948A JP2021527948A JP2022507828A5 JP 2022507828 A5 JP2022507828 A5 JP 2022507828A5 JP 2021527948 A JP2021527948 A JP 2021527948A JP 2021527948 A JP2021527948 A JP 2021527948A JP 2022507828 A5 JP2022507828 A5 JP 2022507828A5
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JP
Japan
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cre0058
cre0065
cre0051
cre0066
crm
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JP2021527948A
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English (en)
Japanese (ja)
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JP2022507828A (ja
JP7489161B2 (ja
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Priority claimed from GBGB1818816.9A external-priority patent/GB201818816D0/en
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Priority to JP2024075266A priority Critical patent/JP2024096349A/ja
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Publication of JP7489161B2 publication Critical patent/JP7489161B2/ja
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JP2021527948A 2018-11-19 2019-11-19 肝臓特異的調節性核酸配列 Active JP7489161B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024075266A JP2024096349A (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1818816.9 2018-11-19
GBGB1818816.9A GB201818816D0 (en) 2018-11-19 2018-11-19 Regulatory nucleic acid sequences
PCT/GB2019/053267 WO2020104782A1 (en) 2018-11-19 2019-11-19 Liver-Specific Regulatory Nucleic Acid Sequences

Related Child Applications (1)

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JP2024075266A Division JP2024096349A (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列

Publications (3)

Publication Number Publication Date
JP2022507828A JP2022507828A (ja) 2022-01-18
JP2022507828A5 true JP2022507828A5 (https=) 2022-11-25
JP7489161B2 JP7489161B2 (ja) 2024-05-23

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ID=64740036

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JP2021527948A Active JP7489161B2 (ja) 2018-11-19 2019-11-19 肝臓特異的調節性核酸配列
JP2024075266A Pending JP2024096349A (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列

Family Applications After (1)

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JP2024075266A Pending JP2024096349A (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列

Country Status (9)

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US (2) US12590129B2 (https=)
EP (2) EP3883951A1 (https=)
JP (2) JP7489161B2 (https=)
CN (1) CN113454104A (https=)
AU (2) AU2019382955B2 (https=)
CA (1) CA3120253A1 (https=)
GB (1) GB201818816D0 (https=)
IL (1) IL283219A (https=)
WO (2) WO2020104782A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117202925A (zh) 2021-01-20 2023-12-08 科罗根科技有限公司 用于治疗和诊断肝癌的Ssu72蛋白或多核苷酸
CN116744961A (zh) 2021-01-29 2023-09-12 科罗根科技有限公司 使用Ssu72治疗肝病的药物组合物
WO2023008925A1 (ko) * 2021-07-29 2023-02-02 주식회사 리보퓨틱스 융합 프로모터, 이를 포함하는 재조합 벡터 및 이를 이용하는 간암 치료용 조성물
CN121358865A (zh) * 2023-04-20 2026-01-16 阿斯克生物公司 肝脏特异性调控核酸序列
CN116555266B (zh) * 2023-06-09 2024-11-12 呈诺再生医学科技(北京)有限公司 肝脏特异性表达的重组启动子和载体及其在肝脏相关疾病治疗中的应用

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US5721096A (en) * 1991-01-24 1998-02-24 Children's Medical Center Corporation Methods of screening for compounds with ability to alter apolipoprotein AI gene expression
US5578444A (en) 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
US6268212B1 (en) 1993-10-18 2001-07-31 Amgen Inc. Tissue specific transgene expression
WO1998009524A1 (en) * 1996-09-06 1998-03-12 Chiron Corporation Methods and compositions for liver specific delivery of therapeutic molecules using recombinant aav vectors
US7351813B2 (en) * 2000-06-20 2008-04-01 The Board Of Trustees Of The Leland Stanford Junior University Liver-specific gene expression cassettes, and methods of use
ATE437221T1 (de) 2001-05-14 2009-08-15 Gbp Ip Llc Lentivirale vektoren kodierend für gerinnungsfaktoren für die gentherapie
CN102634515B (zh) * 2008-02-14 2013-11-06 财团法人牧岩生命工学研究所 适于表达用于基因治疗的编码序列的表达载体
CN102628041B (zh) * 2008-02-14 2013-09-11 财团法人牧岩生命工学研究所 适于表达用于基因治疗的编码序列的表达载体
CA2722238C (en) 2008-04-22 2017-11-28 Life Sciences Research Partners Vzw Liver-specific nucleic acid regulatory elements and methods and use thereof
US8815779B2 (en) * 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
EP2479278A1 (en) * 2011-01-25 2012-07-25 Synpromics Ltd. Method for the construction of specific promoters
US11007280B2 (en) * 2015-03-17 2021-05-18 Vrije Universiteit Brussel Optimized liver-specific expression systems for FVIII and FIX
MX2018012537A (es) * 2016-04-15 2019-02-25 Univ Pennsylvania Terapia de genes para tratar hemofilia a.
WO2018144709A2 (en) * 2017-02-01 2018-08-09 The Trustees Of The University Of Pennsylvania Gene therapy for treating citrullenemia
EP3630160A1 (en) * 2017-05-24 2020-04-08 Universitat Autònoma De Barcelona Viral expression construct comprising a fibroblast growth factor 21 (fgf21) coding sequence
JP2020533971A (ja) * 2017-08-28 2020-11-26 アルター・バイオサイエンス・コーポレーション Il−15をベースとするil−7及びil−21への融合物
CN108588097B (zh) * 2018-04-28 2021-07-13 北京锦篮基因科技有限公司 改造后的hbv基因组和相关组合物及其应用

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