JP2022535412A5 - - Google Patents
Info
- Publication number
- JP2022535412A5 JP2022535412A5 JP2021571874A JP2021571874A JP2022535412A5 JP 2022535412 A5 JP2022535412 A5 JP 2022535412A5 JP 2021571874 A JP2021571874 A JP 2021571874A JP 2021571874 A JP2021571874 A JP 2021571874A JP 2022535412 A5 JP2022535412 A5 JP 2022535412A5
- Authority
- JP
- Japan
- Prior art keywords
- vector
- seq
- promoter
- sequence
- aav9
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1907882.3A GB201907882D0 (en) | 2019-06-03 | 2019-06-03 | Methods |
| GB1907882.3 | 2019-06-03 | ||
| PCT/EP2020/065312 WO2020245169A1 (en) | 2019-06-03 | 2020-06-03 | Aav vectors with myelin protein zero promoter and uses thereof for treating schwann cell-associated diseases like charcot-marie-tooth disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022535412A JP2022535412A (ja) | 2022-08-08 |
| JP2022535412A5 true JP2022535412A5 (https=) | 2023-06-02 |
| JP7692369B2 JP7692369B2 (ja) | 2025-06-13 |
Family
ID=67385825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571874A Active JP7692369B2 (ja) | 2019-06-03 | 2020-06-03 | シャルコー・マリー・トゥース病のようなシュワン細胞関連疾患を治療するためのミエリンタンパク質ゼロのプロモーターを含むａａｖベクター及びその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US12582725B2 (https=) |
| EP (1) | EP3976800A1 (https=) |
| JP (1) | JP7692369B2 (https=) |
| KR (1) | KR20220016485A (https=) |
| CN (1) | CN114026242A (https=) |
| AU (1) | AU2020288605A1 (https=) |
| BR (1) | BR112021024285A2 (https=) |
| CA (1) | CA3142211A1 (https=) |
| CL (1) | CL2021003201A1 (https=) |
| CO (1) | CO2021016487A2 (https=) |
| EA (1) | EA202290001A1 (https=) |
| GB (1) | GB201907882D0 (https=) |
| IL (1) | IL288462A (https=) |
| MX (1) | MX2021014789A (https=) |
| SG (1) | SG11202112889VA (https=) |
| WO (1) | WO2020245169A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022140521A1 (en) * | 2020-12-22 | 2022-06-30 | Wisconsin Alumni Research Foundation | Regulatory elements for schwann cell-specific gene expression |
| EP4413131A1 (en) | 2021-10-07 | 2024-08-14 | Research Institute at Nationwide Children's Hospital | Products and methods for myelin protein zero silencing and treating cmt1b disease |
| WO2023136624A1 (ko) | 2022-01-13 | 2023-07-20 | 주식회사 툴젠 | 슈반 세포 특이적 프로모터 |
| GB202303495D0 (en) * | 2023-03-09 | 2023-04-26 | Ucl Business Ltd | Therapy for charcot-marie-tooth disease |
| WO2025105734A1 (ko) * | 2023-11-15 | 2025-05-22 | 주식회사 카인사이언스 | 탈수초 질환 치료용 펩타이드 및 이의 용도 |
| KR20250126990A (ko) * | 2024-02-16 | 2025-08-26 | 주식회사 엣진 | 샤르코-마리-투스 질환 치료를 위한 징크 핑거 단백질 및 이를 발현시키는 방법 |
| CN118291543A (zh) * | 2024-02-29 | 2024-07-05 | 神拓生物技术(杭州)有限公司 | 一种二型神经纤维瘤基因治疗的慢病毒载体及其应用 |
| KR20260001543A (ko) * | 2024-06-25 | 2026-01-06 | 연세대학교 산학협력단 | 바이러스 벡터를 포함한 난청 치료용 조성물 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL210751B1 (pl) | 2006-09-12 | 2012-02-29 | Anna Jurewicz | Izolowany fragment białka Nogo-A, jego zastosowanie oraz sposób diagnozowania oraz leczenia stwardnienia rozsianego i polineuropatii zapalno-demielinizacyjnej |
| WO2008073303A2 (en) | 2006-12-07 | 2008-06-19 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways, tools, and methods |
| US20090215178A1 (en) | 2008-02-22 | 2009-08-27 | Zequn Tang | Methods to enhance the stability and homogeneity of transgene expression in clonal cell lines |
| AU2009271524A1 (en) | 2008-07-16 | 2010-01-21 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of GM98 (MRF) in remyelination |
| US20120233713A1 (en) | 2009-09-02 | 2012-09-13 | Brian Popko | Methods and systems for inducible ablation of neural cells |
| EP2561073B1 (en) | 2010-04-23 | 2016-08-24 | University of Massachusetts | Cns targeting aav vectors and methods of use thereof |
| EP2713724A4 (en) | 2011-05-26 | 2015-03-11 | Biogen Idec Inc | METHODS OF TREATING MULTIPLE SCLEROSIS AND PRESERVING AND / OR INCREASING MYELINE CONTENT |
| CN107551269A (zh) | 2012-02-29 | 2018-01-09 | 百深公司 | 周围神经的IgG刺激髓鞘再生 |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9644215B2 (en) | 2013-04-12 | 2017-05-09 | The General Hospital Corporation | AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors |
| WO2015140351A1 (en) | 2014-03-21 | 2015-09-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for enhancing myelination |
| EP2933335A1 (en) | 2014-04-18 | 2015-10-21 | Genethon | A method of treating peripheral neuropathies and motor neuron diseases |
| CN114657141B (zh) | 2014-09-12 | 2025-02-25 | 京都府公立大学法人 | 雪旺氏细胞及其制备方法 |
| US20180305689A1 (en) | 2015-04-22 | 2018-10-25 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| JP6981973B2 (ja) | 2015-10-01 | 2021-12-17 | ヒート バイオロジクス，インコーポレイテッド | Ｉ型及びｉｉ型細胞外ドメインを異種キメラタンパク質として連結する組成物及び方法 |
| WO2018056412A1 (ja) | 2016-09-23 | 2018-03-29 | 国立大学法人大阪大学 | シュワン細胞分化促進剤及び末梢神経再生促進剤 |
| KR102622411B1 (ko) | 2016-10-14 | 2024-01-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵염기 에디터의 aav 전달 |
| KR102437228B1 (ko) | 2016-11-14 | 2022-08-30 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| WO2018106753A1 (en) | 2016-12-07 | 2018-06-14 | The General Hospital Corporation | Methods and compositions relating the treatment of tumors |
| CN118581154A (zh) | 2017-06-02 | 2024-09-03 | 国家健康与医学研究院 | 用于遗传障碍的基因疗法的基因组编辑手段和结合病毒载体的基因疗法 |
| AU2018345772B2 (en) | 2017-10-02 | 2025-04-17 | Research Institute At Nationwide Children's Hospital | MiRNA detargeting system for tissue specific interference |
| US11926653B2 (en) | 2017-10-20 | 2024-03-12 | Research Institute At Nationwide Children's Hospital | Methods and materials for NT-3 gene therapy |
| IL299762A (en) | 2020-07-13 | 2023-03-01 | Univ Pennsylvania | Useful preparations for the treatment of Charcot-Marietot disease |
-
2019
- 2019-06-03 GB GBGB1907882.3A patent/GB201907882D0/en not_active Ceased
-
2020
- 2020-06-03 MX MX2021014789A patent/MX2021014789A/es unknown
- 2020-06-03 AU AU2020288605A patent/AU2020288605A1/en active Pending
- 2020-06-03 EA EA202290001A patent/EA202290001A1/ru unknown
- 2020-06-03 KR KR1020217042344A patent/KR20220016485A/ko not_active Ceased
- 2020-06-03 BR BR112021024285A patent/BR112021024285A2/pt unknown
- 2020-06-03 WO PCT/EP2020/065312 patent/WO2020245169A1/en not_active Ceased
- 2020-06-03 CN CN202080040867.3A patent/CN114026242A/zh active Pending
- 2020-06-03 JP JP2021571874A patent/JP7692369B2/ja active Active
- 2020-06-03 SG SG11202112889VA patent/SG11202112889VA/en unknown
- 2020-06-03 CA CA3142211A patent/CA3142211A1/en active Pending
- 2020-06-03 US US17/616,006 patent/US12582725B2/en active Active
- 2020-06-03 EP EP20732138.1A patent/EP3976800A1/en active Pending
-
2021
- 2021-11-28 IL IL288462A patent/IL288462A/en unknown
- 2021-12-01 CL CL2021003201A patent/CL2021003201A1/es unknown
- 2021-12-02 CO CONC2021/0016487A patent/CO2021016487A2/es unknown
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