JP2021526858A5 - - Google Patents
Info
- Publication number
- JP2021526858A5 JP2021526858A5 JP2021518052A JP2021518052A JP2021526858A5 JP 2021526858 A5 JP2021526858 A5 JP 2021526858A5 JP 2021518052 A JP2021518052 A JP 2021518052A JP 2021518052 A JP2021518052 A JP 2021518052A JP 2021526858 A5 JP2021526858 A5 JP 2021526858A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- composition according
- binding polypeptide
- polypeptide
- promoter
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862682271P | 2018-06-08 | 2018-06-08 | |
| US62/682,271 | 2018-06-08 | ||
| PCT/US2019/036021 WO2019236982A1 (en) | 2018-06-08 | 2019-06-07 | Rna-targeting fusion protein compositions and methods for use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021526858A JP2021526858A (ja) | 2021-10-11 |
| JPWO2019236982A5 JPWO2019236982A5 (https=) | 2022-06-15 |
| JP2021526858A5 true JP2021526858A5 (https=) | 2022-06-15 |
Family
ID=68769584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518052A Pending JP2021526858A (ja) | 2018-06-08 | 2019-06-07 | Ｒｎａ標的化融合タンパク質組成物および使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20200071718A1 (https=) |
| EP (1) | EP3802812A4 (https=) |
| JP (1) | JP2021526858A (https=) |
| KR (1) | KR20210058806A (https=) |
| CN (1) | CN112930395A (https=) |
| AU (1) | AU2019280990A1 (https=) |
| CA (1) | CA3102779A1 (https=) |
| SG (1) | SG11202012004SA (https=) |
| WO (1) | WO2019236982A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9499805B2 (en) | 2010-06-18 | 2016-11-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for synthetic RNA endonucleases |
| US20190284553A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| AU2020208346B2 (en) | 2019-01-14 | 2026-01-29 | University Of Rochester | Targeted nuclear RNA cleavage and polyadenylation with CRISPR-cas |
| EP4004206A1 (en) * | 2019-07-23 | 2022-06-01 | University of Rochester | Targeted rna cleavage with crispr-cas |
| WO2022020431A2 (en) * | 2020-07-21 | 2022-01-27 | Trustees Of Boston University | Inducible control of gene expression |
| CN112126645B (zh) * | 2020-09-11 | 2021-06-01 | 广州吉赛生物科技股份有限公司 | 一种环形rna敲低方法及其应用 |
| CN112430597A (zh) * | 2020-11-24 | 2021-03-02 | 深圳市瑞吉生物科技有限公司 | 一种使目的基因沉默的CasRx制剂及其应用 |
| KR20230127221A9 (ko) * | 2020-12-01 | 2024-12-06 | 로카나바이오 인크. | Cag 반복 질환을 치료하기 위한 rna 표적화 조성물 및 방법 |
| US20240108751A1 (en) * | 2020-12-01 | 2024-04-04 | Locanabio, Inc. | Rna-targeting compositions and methods for treating myotonic dystrophy type 1 |
| GB202105455D0 (en) | 2021-04-16 | 2021-06-02 | Ucl Business Ltd | Composition |
| WO2022256414A1 (en) * | 2021-06-02 | 2022-12-08 | The Regents Of The University Of California | Rna recognition complex and uses thereof |
| US20250163475A1 (en) * | 2021-12-27 | 2025-05-22 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Systems and methods for cell modification |
| CN114835776B (zh) * | 2022-04-08 | 2023-09-01 | 陕西师范大学 | 一种靶向Smad4/PELO相互作用的抵抗肿瘤转移小分子多肽及应用 |
| CN116949011A (zh) * | 2022-04-26 | 2023-10-27 | 中国科学院动物研究所 | 经分离的Cas13蛋白、基于它的基因编辑系统及其用途 |
| US20250382596A1 (en) * | 2022-10-28 | 2025-12-18 | The Regents Of The University Of California | Recombinant enhanced antiviral restrictors |
| CN115820603B (zh) * | 2022-11-15 | 2024-07-05 | 吉林大学 | 一种基于dCasRx-NSUN6单基因特异性M5C修饰编辑方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100750788B1 (ko) * | 2003-09-18 | 2007-08-20 | 아이시스 파마수티컬즈 인코포레이티드 | ｅＩＦ4Ｅ 발현의 조정 |
| US20110002981A1 (en) * | 2006-12-20 | 2011-01-06 | Kolattukudy Pappachan E | MCPIP Protection Against Cardiac Dysfunction |
| US9499805B2 (en) * | 2010-06-18 | 2016-11-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for synthetic RNA endonucleases |
| WO2012068627A1 (en) | 2010-11-24 | 2012-05-31 | The University Of Western Australia | Peptides for the specific binding of rna targets |
| WO2013058404A1 (ja) | 2011-10-21 | 2013-04-25 | 国立大学法人九州大学 | Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用 |
| JP6793547B2 (ja) * | 2013-12-12 | 2020-12-02 | ザ・ブロード・インスティテュート・インコーポレイテッド | 最適化機能ＣＲＩＳＰＲ−Ｃａｓ系による配列操作のための系、方法および組成物 |
| WO2015138855A1 (en) * | 2014-03-14 | 2015-09-17 | The Regents Of The University Of California | Vectors and methods for fungal genome engineering by crispr-cas9 |
| US10330674B2 (en) | 2015-01-13 | 2019-06-25 | Massachusetts Institute Of Technology | Pumilio domain-based modular protein architecture for RNA binding |
| EP3303634B1 (en) | 2015-06-03 | 2023-08-30 | The Regents of The University of California | Cas9 variants and methods of use thereof |
| JP2019500899A (ja) * | 2015-11-23 | 2019-01-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ＣＲＩＳＰＲ／Ｃａｓ９の核送達を通じた細胞ＲＮＡの追跡と操作 |
| EA201891338A1 (ru) | 2015-12-04 | 2018-12-28 | Новартис Аг | Композиции и способы для иммуноонкологии |
| WO2017189821A1 (en) * | 2016-04-29 | 2017-11-02 | Bio-Rad Laboratories, Inc. | Dimeric proteins for specific targeting of nucleic acid sequences |
| US12180499B2 (en) | 2016-10-31 | 2024-12-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for impeding transcription of expanded microsatellite repeats |
| AU2018234825B2 (en) | 2017-03-15 | 2020-12-17 | Massachusetts Institute Of Technology | Novel CAS13B orthologues CRISPR enzymes and systems |
| US11415574B2 (en) | 2017-03-31 | 2022-08-16 | NeuroDiagnostics LLC | Lymphocyte-based morphometric test for alzheimer's disease |
| US11168322B2 (en) | 2017-06-30 | 2021-11-09 | Arbor Biotechnologies, Inc. | CRISPR RNA targeting enzymes and systems and uses thereof |
| US10476825B2 (en) | 2017-08-22 | 2019-11-12 | Salk Institue for Biological Studies | RNA targeting methods and compositions |
| US20190382759A1 (en) | 2018-06-08 | 2019-12-19 | Locana, Inc. | Compositions and methods for the modulation of adaptive immunity |
| JP2021533803A (ja) * | 2018-08-24 | 2021-12-09 | ロックアネイビオ， インコーポレイテッド | Ｆａｓｌ免疫モジュレート遺伝子治療組成物および使用方法 |
-
2019
- 2019-06-07 JP JP2021518052A patent/JP2021526858A/ja active Pending
- 2019-06-07 WO PCT/US2019/036021 patent/WO2019236982A1/en not_active Ceased
- 2019-06-07 CA CA3102779A patent/CA3102779A1/en active Pending
- 2019-06-07 KR KR1020217000538A patent/KR20210058806A/ko not_active Abandoned
- 2019-06-07 US US16/434,689 patent/US20200071718A1/en not_active Abandoned
- 2019-06-07 CN CN201980050249.4A patent/CN112930395A/zh active Pending
- 2019-06-07 EP EP19815645.7A patent/EP3802812A4/en not_active Withdrawn
- 2019-06-07 SG SG11202012004SA patent/SG11202012004SA/en unknown
- 2019-06-07 AU AU2019280990A patent/AU2019280990A1/en not_active Abandoned
- 2019-12-20 US US16/723,079 patent/US10822617B2/en not_active Expired - Fee Related
-
2020
- 2020-08-24 US US17/001,318 patent/US20210047654A1/en not_active Abandoned
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