JP2021526858A5 - - Google Patents
Info
- Publication number
- JP2021526858A5 JP2021526858A5 JP2021518052A JP2021518052A JP2021526858A5 JP 2021526858 A5 JP2021526858 A5 JP 2021526858A5 JP 2021518052 A JP2021518052 A JP 2021518052A JP 2021518052 A JP2021518052 A JP 2021518052A JP 2021526858 A5 JP2021526858 A5 JP 2021526858A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- composition according
- binding polypeptide
- polypeptide
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862682271P | 2018-06-08 | 2018-06-08 | |
| US62/682,271 | 2018-06-08 | ||
| PCT/US2019/036021 WO2019236982A1 (en) | 2018-06-08 | 2019-06-07 | Rna-targeting fusion protein compositions and methods for use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021526858A JP2021526858A (ja) | 2021-10-11 |
| JP2021526858A5 true JP2021526858A5 (https=) | 2022-06-15 |
Family
ID=68769584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518052A Pending JP2021526858A (ja) | 2018-06-08 | 2019-06-07 | Ｒｎａ標的化融合タンパク質組成物および使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20200071718A1 (https=) |
| EP (1) | EP3802812A4 (https=) |
| JP (1) | JP2021526858A (https=) |
| KR (1) | KR20210058806A (https=) |
| CN (1) | CN112930395A (https=) |
| AU (1) | AU2019280990A1 (https=) |
| CA (1) | CA3102779A1 (https=) |
| SG (1) | SG11202012004SA (https=) |
| WO (1) | WO2019236982A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011160052A2 (en) | 2010-06-18 | 2011-12-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for sequence specific rna endonucleases |
| US20190284553A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| AU2020208346B2 (en) * | 2019-01-14 | 2026-01-29 | University Of Rochester | Targeted nuclear RNA cleavage and polyadenylation with CRISPR-cas |
| US20220267773A1 (en) * | 2019-07-23 | 2022-08-25 | University Of Rochester | Targeted RNA cleavage with CRISPR-Cas |
| US11572565B2 (en) | 2020-07-21 | 2023-02-07 | Trustees Of Boston University | Inducible control of gene expression |
| CN112126645B (zh) * | 2020-09-11 | 2021-06-01 | 广州吉赛生物科技股份有限公司 | 一种环形rna敲低方法及其应用 |
| CN112430597A (zh) * | 2020-11-24 | 2021-03-02 | 深圳市瑞吉生物科技有限公司 | 一种使目的基因沉默的CasRx制剂及其应用 |
| WO2022119974A1 (en) * | 2020-12-01 | 2022-06-09 | Locanabio, Inc. | Rna-targeting compositions and methods for treating cag repeat diseases |
| JP2023551874A (ja) * | 2020-12-01 | 2023-12-13 | ロックアネイビオ， インコーポレイテッド | 筋強直性ジストロフィー１型を処置するためのｒｎａ標的化組成物および方法 |
| GB202105455D0 (en) | 2021-04-16 | 2021-06-02 | Ucl Business Ltd | Composition |
| WO2022256414A1 (en) * | 2021-06-02 | 2022-12-08 | The Regents Of The University Of California | Rna recognition complex and uses thereof |
| CN118541475A (zh) * | 2021-12-27 | 2024-08-23 | 亘喜生物科技（上海）有限公司 | 用于细胞修饰的系统和方法 |
| CN114835776B (zh) * | 2022-04-08 | 2023-09-01 | 陕西师范大学 | 一种靶向Smad4/PELO相互作用的抵抗肿瘤转移小分子多肽及应用 |
| CN116949011A (zh) * | 2022-04-26 | 2023-10-27 | 中国科学院动物研究所 | 经分离的Cas13蛋白、基于它的基因编辑系统及其用途 |
| WO2024092230A2 (en) * | 2022-10-28 | 2024-05-02 | The Regents Of The University Of California | Recombinant enhanced antiviral restrictors |
| CN115820603B (zh) * | 2022-11-15 | 2024-07-05 | 吉林大学 | 一种基于dCasRx-NSUN6单基因特异性M5C修饰编辑方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2256201A3 (en) * | 2003-09-18 | 2012-07-04 | Isis Pharmaceuticals, Inc. | Modulation of eIF4E expression |
| US20110002981A1 (en) * | 2006-12-20 | 2011-01-06 | Kolattukudy Pappachan E | MCPIP Protection Against Cardiac Dysfunction |
| WO2011160052A2 (en) * | 2010-06-18 | 2011-12-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for sequence specific rna endonucleases |
| WO2012068627A1 (en) | 2010-11-24 | 2012-05-31 | The University Of Western Australia | Peptides for the specific binding of rna targets |
| DK2784157T3 (da) | 2011-10-21 | 2019-10-21 | Univ Kyushu Nat Univ Corp | Designfremgangsmåde til et rna-bindende protein under anvendelse af ppr-motiv og anvendelse deraf |
| JP6793547B2 (ja) * | 2013-12-12 | 2020-12-02 | ザ・ブロード・インスティテュート・インコーポレイテッド | 最適化機能ＣＲＩＳＰＲ−Ｃａｓ系による配列操作のための系、方法および組成物 |
| US20170088845A1 (en) * | 2014-03-14 | 2017-03-30 | The Regents Of The University Of California | Vectors and methods for fungal genome engineering by crispr-cas9 |
| US10330674B2 (en) | 2015-01-13 | 2019-06-25 | Massachusetts Institute Of Technology | Pumilio domain-based modular protein architecture for RNA binding |
| WO2016196655A1 (en) | 2015-06-03 | 2016-12-08 | The Regents Of The University Of California | Cas9 variants and methods of use thereof |
| CA3005968A1 (en) * | 2015-11-23 | 2017-06-01 | The Regents Of The University Of California | Tracking and manipulating cellular rna via nuclear delivery of crispr/cas9 |
| WO2017093969A1 (en) | 2015-12-04 | 2017-06-08 | Novartis Ag | Compositions and methods for immunooncology |
| CN109152808A (zh) * | 2016-04-29 | 2019-01-04 | 生物辐射实验室股份有限公司 | 用于核酸序列的特异性靶向的二聚蛋白质 |
| US12180499B2 (en) | 2016-10-31 | 2024-12-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for impeding transcription of expanded microsatellite repeats |
| JP2020511141A (ja) | 2017-03-15 | 2020-04-16 | ザ・ブロード・インスティテュート・インコーポレイテッド | 新規Ｃａｓ１３ｂオルソログＣＲＩＳＰＲ酵素及び系 |
| EP3600027B1 (en) | 2017-03-31 | 2026-02-18 | Neurodiagnostics LLC | Lymphocyte-based morphometric test for alzheimer's disease |
| US10392616B2 (en) | 2017-06-30 | 2019-08-27 | Arbor Biotechnologies, Inc. | CRISPR RNA targeting enzymes and systems and uses thereof |
| US10476825B2 (en) | 2017-08-22 | 2019-11-12 | Salk Institue for Biological Studies | RNA targeting methods and compositions |
| SG11202012015YA (en) | 2018-06-08 | 2021-01-28 | Locanabio Inc | Compositions and methods for the modulation of adaptive immunity |
| CA3110282A1 (en) * | 2018-08-24 | 2020-02-27 | Locanabio, Inc. | Fasl immunomodulatory gene therapy compositions and methods for use |
-
2019
- 2019-06-07 KR KR1020217000538A patent/KR20210058806A/ko not_active Abandoned
- 2019-06-07 SG SG11202012004SA patent/SG11202012004SA/en unknown
- 2019-06-07 US US16/434,689 patent/US20200071718A1/en not_active Abandoned
- 2019-06-07 AU AU2019280990A patent/AU2019280990A1/en not_active Abandoned
- 2019-06-07 CN CN201980050249.4A patent/CN112930395A/zh active Pending
- 2019-06-07 EP EP19815645.7A patent/EP3802812A4/en not_active Withdrawn
- 2019-06-07 WO PCT/US2019/036021 patent/WO2019236982A1/en not_active Ceased
- 2019-06-07 JP JP2021518052A patent/JP2021526858A/ja active Pending
- 2019-06-07 CA CA3102779A patent/CA3102779A1/en active Pending
- 2019-12-20 US US16/723,079 patent/US10822617B2/en not_active Expired - Fee Related
-
2020
- 2020-08-24 US US17/001,318 patent/US20210047654A1/en not_active Abandoned
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