JP2022506111A5 - - Google Patents
Info
- Publication number
- JP2022506111A5 JP2022506111A5 JP2021523279A JP2021523279A JP2022506111A5 JP 2022506111 A5 JP2022506111 A5 JP 2022506111A5 JP 2021523279 A JP2021523279 A JP 2021523279A JP 2021523279 A JP2021523279 A JP 2021523279A JP 2022506111 A5 JP2022506111 A5 JP 2022506111A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- eye disease
- pharmaceutical composition
- uveitis
- pharmaceutically acceptable
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862751967P | 2018-10-29 | 2018-10-29 | |
| US62/751,967 | 2018-10-29 | ||
| PCT/US2019/056947 WO2020092019A1 (en) | 2018-10-29 | 2019-10-18 | 2-azabicyclo hexane compound as jak inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022506111A JP2022506111A (ja) | 2022-01-17 |
| JP2022506111A5 true JP2022506111A5 (https=) | 2022-09-01 |
| JPWO2020092019A5 JPWO2020092019A5 (https=) | 2022-09-01 |
Family
ID=68542755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523279A Withdrawn JP2022506111A (ja) | 2018-10-29 | 2019-10-18 | Ｊａｋ阻害剤としての２－アザビシクロヘキサン化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10968222B2 (https=) |
| EP (1) | EP3853229A1 (https=) |
| JP (1) | JP2022506111A (https=) |
| KR (1) | KR20210084512A (https=) |
| CN (1) | CN112955451A (https=) |
| AU (1) | AU2019373059A1 (https=) |
| BR (1) | BR112021007788A8 (https=) |
| CA (1) | CA3113667A1 (https=) |
| IL (1) | IL282460A (https=) |
| MX (1) | MX2021004582A (https=) |
| SG (1) | SG11202103042XA (https=) |
| WO (1) | WO2020092019A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10029013B2 (en) | 2009-10-02 | 2018-07-24 | Foamix Pharmaceuticals Ltd. | Surfactant-free, water-free formable composition and breakable foams and their uses |
| HK1252685A1 (zh) | 2015-11-03 | 2019-05-31 | Theravance Biopharma R&D Ip, Llc | 用於治疗呼吸疾病的jak激酶抑制剂化合物 |
| MX377365B (es) | 2016-09-08 | 2025-03-10 | Journey Medical Corp | Composiciones y métodos para tratar rosácea y acné. |
| PT3837258T (pt) | 2018-09-04 | 2024-06-20 | Theravance Biopharma R&D Ip Llc | Amidas de dimetil amino azetidina como inibidores de jak |
| WO2020051139A1 (en) | 2018-09-04 | 2020-03-12 | Theravance Biopharma R&D Ip, Llc | 5 to 7 membered heterocyclic amides as jak inhibitors |
| CA3108848A1 (en) | 2018-09-04 | 2020-03-12 | Theravance Biopharma R&D Ip, Llc | Process for preparing jak inhibitors and intermediates thereof |
| TW202144343A (zh) | 2020-03-02 | 2021-12-01 | 美商施萬生物製藥研發 Ip有限責任公司 | Jak抑制劑化合物之結晶水合物 |
| CN111620868B (zh) * | 2020-05-28 | 2021-08-31 | 爱斯特（成都）生物制药股份有限公司 | 一种1H-吡唑并[3,4-b]吡啶-3-甲醛的制备方法 |
| CN111973599A (zh) * | 2020-08-07 | 2020-11-24 | 杭州邦顺制药有限公司 | 用于眼部疾病治疗的化合物 |
| EP4196477A4 (en) * | 2020-08-17 | 2024-10-09 | Vyne Therapeutics Inc. | TOFACITINIB-CONTAINING ANHYDROUS ELASTOMER-BASED GEL FORMULATIONS |
| TW202317550A (zh) | 2021-06-25 | 2023-05-01 | 美商施萬生物製藥研發 Ip有限責任公司 | 作為jak抑制劑之咪唑吲唑化合物 |
| CN114181055A (zh) * | 2021-12-21 | 2022-03-15 | 苏州楚凯药业有限公司 | 1-苄氧基-4-溴-5-乙基-2-氟苯的制备方法 |
| CN115969796B (zh) * | 2022-12-06 | 2024-07-09 | 苏州大学 | 一种jak抑制剂长效微球及其制备方法与应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI262914B (en) | 1999-07-02 | 2006-10-01 | Agouron Pharma | Compounds and pharmaceutical compositions for inhibiting protein kinases |
| JP4836788B2 (ja) | 2003-07-23 | 2011-12-14 | エグゼリクシス， インコーポレイテッド | 未分化リンパ腫キナーゼ変調因子及びその使用法 |
| US20050090529A1 (en) | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| US7884109B2 (en) | 2005-04-05 | 2011-02-08 | Wyeth Llc | Purine and imidazopyridine derivatives for immunosuppression |
| US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| JP2010111624A (ja) | 2008-11-06 | 2010-05-20 | Shionogi & Co Ltd | Ｔｔｋ阻害作用を有するインダゾール誘導体 |
| EP2414340A1 (en) | 2009-04-03 | 2012-02-08 | Dainippon Sumitomo Pharma Co., Ltd. | Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof |
| EP2515655B1 (en) | 2009-12-21 | 2015-08-05 | Samumed, LLC | 1h-pyrazolo[3,4-beta]pyridines and therapeutic uses thereof |
| US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| MX368464B (es) | 2013-12-05 | 2019-10-02 | Pfizer | Acrilamidas de pirrolo[2,3-d]pirimidinilo, pirrolo[2,3-b]pirazinil o y pirrolo[2,3-d]piridinilo. |
| CR20160525A (es) | 2014-05-14 | 2016-12-20 | Pfizer | Pirazolopiridinas y pirazolopirimidinas |
| WO2016026078A1 (en) | 2014-08-19 | 2016-02-25 | Changzhou Jiekai Pharmatech Co., Ltd. | Heterocyclic compounds as erk inhibitors |
| KR101663277B1 (ko) | 2015-03-30 | 2016-10-06 | 주식회사 녹십자 | TNIK, IKKε 및 TBK1 억제제로서의 피라졸계 유도체 및 이를 포함하는 약학적 조성물 |
| EP3712152B1 (en) * | 2015-11-03 | 2021-01-13 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors |
| HK1252685A1 (zh) | 2015-11-03 | 2019-05-31 | Theravance Biopharma R&D Ip, Llc | 用於治疗呼吸疾病的jak激酶抑制剂化合物 |
| US10556901B2 (en) * | 2015-11-03 | 2020-02-11 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as Janus kinase inhibitors |
| BR112019018648A2 (pt) | 2017-03-09 | 2020-06-16 | Theravance Biopharma R&D Ip, Llc | Inibidores de jak contendo uma amida heterocíclica com 4 membros |
| US10406148B2 (en) | 2017-05-01 | 2019-09-10 | Theravance Biopharma R&D Ip, Llc | Methods of treatment using a JAK inhibitor compound |
| AR111495A1 (es) | 2017-05-01 | 2019-07-17 | Theravance Biopharma R&D Ip Llc | Compuestos de imidazo-piperidina fusionada como inhibidores de jak |
| CN110603255B (zh) | 2017-05-01 | 2023-02-10 | 施万生物制药研发Ip有限责任公司 | Jak抑制剂化合物的结晶型式 |
| FI3932919T3 (fi) | 2019-02-25 | 2024-08-30 | Henan Medinno Pharmaceutical Tech Co Ltd | Jak-inhibiittoriyhdiste ja sen käyttö |
| MA55201A (fr) | 2019-03-05 | 2022-01-12 | Incyte Corp | Inhibiteurs de la voie jak1 pour le traitement d'un dysfonctionnement chronique de l'allogreffe pulmonaire |
| CN112279848A (zh) | 2019-07-25 | 2021-01-29 | 四川海思科制药有限公司 | 一种泛JAKs抑制剂及其用途 |
-
2019
- 2019-10-18 MX MX2021004582A patent/MX2021004582A/es unknown
- 2019-10-18 US US16/656,946 patent/US10968222B2/en not_active Expired - Fee Related
- 2019-10-18 EP EP19802351.7A patent/EP3853229A1/en not_active Withdrawn
- 2019-10-18 KR KR1020217015109A patent/KR20210084512A/ko not_active Withdrawn
- 2019-10-18 WO PCT/US2019/056947 patent/WO2020092019A1/en not_active Ceased
- 2019-10-18 BR BR112021007788A patent/BR112021007788A8/pt not_active Application Discontinuation
- 2019-10-18 SG SG11202103042XA patent/SG11202103042XA/en unknown
- 2019-10-18 CN CN201980070126.7A patent/CN112955451A/zh active Pending
- 2019-10-18 JP JP2021523279A patent/JP2022506111A/ja not_active Withdrawn
- 2019-10-18 AU AU2019373059A patent/AU2019373059A1/en not_active Abandoned
- 2019-10-18 CA CA3113667A patent/CA3113667A1/en active Pending
-
2021
- 2021-03-01 US US17/249,373 patent/US20210206764A1/en not_active Abandoned
- 2021-04-20 IL IL282460A patent/IL282460A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022506111A5 (https=) | ||
| US11248000B2 (en) | Quinazoline and indole compounds to treat medical disorders | |
| EP3985002B1 (en) | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | |
| JP2023099094A5 (https=) | ||
| JPWO2020092019A5 (https=) | ||
| US20170057983A1 (en) | Phosphonate Compounds for Treatment of Medical Disorders | |
| TW201718551A (zh) | 用於治療醫學病症之醯胺化合物 | |
| TWI710555B (zh) | 新穎水溶性前藥 | |
| CN110343135A (zh) | 替诺福韦艾拉酚胺(tenofovir alafenamide)半反丁烯二酸盐 | |
| TW201720438A (zh) | 用於治療醫學病症之化合物 | |
| WO2018160891A1 (en) | Pharmaceutical compounds for treatment of medical disorders | |
| CN109069508A (zh) | Ezh2抑制剂及其用途 | |
| WO2017035351A1 (en) | Amino compounds for treatment of medical disorders | |
| CN112839945A (zh) | 补体因子d抑制剂的形态形式 | |
| JP2017524025A5 (https=) | ||
| JP7330510B2 (ja) | 非滲出型または萎縮型の黄斑変性にて以前に失われた視力を回復させるための医薬組成物 | |
| JP7443375B2 (ja) | 医学的障害の治療のための大環状化合物 | |
| JP2022519924A (ja) | 補体媒介性障害の治療のための医薬化合物 | |
| JP2021516271A5 (https=) | ||
| JP2020535161A5 (https=) | ||
| JP2021530543A5 (https=) | ||
| JP2016537432A5 (https=) | ||
| JP6488000B2 (ja) | ２−シアノ−３−シクロプロピル−３−ヒドロキシ−ｎ−アリール−チオアクリルアミド誘導体 | |
| JPWO2020163268A5 (https=) | ||
| JP2020530459A5 (https=) |