JP2023099094A5 - - Google Patents
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- JP2023099094A5 JP2023099094A5 JP2023073187A JP2023073187A JP2023099094A5 JP 2023099094 A5 JP2023099094 A5 JP 2023099094A5 JP 2023073187 A JP2023073187 A JP 2023073187A JP 2023073187 A JP2023073187 A JP 2023073187A JP 2023099094 A5 JP2023099094 A5 JP 2023099094A5
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- JP
- Japan
- Prior art keywords
- initiation
- treatment
- monthly
- disease
- administrations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025034492A JP7852107B2 (ja) | 2018-02-06 | 2025-03-05 | 眼科疾患の処置 |
| JP2025034493A JP7852108B2 (ja) | 2018-02-06 | 2025-03-05 | 眼科疾患の処置 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862627103P | 2018-02-06 | 2018-02-06 | |
| US62/627,103 | 2018-02-06 | ||
| US201862729333P | 2018-09-10 | 2018-09-10 | |
| US62/729,333 | 2018-09-10 | ||
| JP2022000341A JP7273204B2 (ja) | 2018-02-06 | 2022-01-05 | 眼科疾患の処置 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022000341A Division JP7273204B2 (ja) | 2018-02-06 | 2022-01-05 | 眼科疾患の処置 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025034493A Division JP7852108B2 (ja) | 2018-02-06 | 2025-03-05 | 眼科疾患の処置 |
| JP2025034492A Division JP7852107B2 (ja) | 2018-02-06 | 2025-03-05 | 眼科疾患の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023099094A JP2023099094A (ja) | 2023-07-11 |
| JP2023099094A5 true JP2023099094A5 (https=) | 2024-12-20 |
| JP7646727B2 JP7646727B2 (ja) | 2025-03-17 |
Family
ID=65352014
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020536578A Active JP7005772B2 (ja) | 2018-02-06 | 2019-02-05 | 眼科疾患の処置 |
| JP2022000341A Active JP7273204B2 (ja) | 2018-02-06 | 2022-01-05 | 眼科疾患の処置 |
| JP2023073187A Active JP7646727B2 (ja) | 2018-02-06 | 2023-04-27 | 眼科疾患の処置 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020536578A Active JP7005772B2 (ja) | 2018-02-06 | 2019-02-05 | 眼科疾患の処置 |
| JP2022000341A Active JP7273204B2 (ja) | 2018-02-06 | 2022-01-05 | 眼科疾患の処置 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20210139576A1 (https=) |
| EP (1) | EP3749359A1 (https=) |
| JP (3) | JP7005772B2 (https=) |
| KR (3) | KR20250166355A (https=) |
| CN (4) | CN111699004A (https=) |
| AU (3) | AU2019219004B2 (https=) |
| CA (1) | CA3088355A1 (https=) |
| IL (1) | IL276383B2 (https=) |
| MX (1) | MX2020007527A (https=) |
| SG (1) | SG11202006712XA (https=) |
| TW (3) | TW202535932A (https=) |
| WO (1) | WO2019154776A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR102799807B1 (ko) | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| FI3743091T3 (fi) | 2018-01-26 | 2025-01-03 | Univ California | Menetelmät ja koostumukset verisuoniperäisten sairauksien hoitoon käyttämällä anti-vegf vaikuttavia aineita |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| EP3873519A1 (en) | 2018-10-29 | 2021-09-08 | F. Hoffmann-La Roche AG | Antibody formulation |
| CN118718181A (zh) | 2019-06-05 | 2024-10-01 | 里珍纳龙药品有限公司 | 用于精确剂量递送的装置及方法 |
| CA3145239A1 (en) * | 2019-08-06 | 2021-02-11 | Hugh LIN | Personalized treatment of ophthalmologic diseases |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2021108255A1 (en) | 2019-11-25 | 2021-06-03 | The Regents Of The University Of California | Long-acting vegf inhibitors for intraocular neovascularization |
| PH12023550015A1 (en) | 2020-07-16 | 2024-03-11 | Novartis Ag | Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules |
| JP7158626B1 (ja) | 2020-09-04 | 2022-10-21 | エフ．ホフマン－ラ ロシュ アーゲー | Ｖｅｇｆ－ａ及びａｎｇ２に結合する抗体及び使用方法 |
| TW202221027A (zh) * | 2020-09-17 | 2022-06-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 特異性結合ｖｅｇｆ和ａｎｇ－２的雙特異性抗原結合分子 |
| JP2024512701A (ja) * | 2021-03-30 | 2024-03-19 | アブプロ コーポレーション | 抗ａｎｇ２×ｖｅｇｆ多重特異性抗体を用いて脈絡膜新生血管形成を治療するための方法 |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
| WO2023028004A1 (en) * | 2021-08-23 | 2023-03-02 | Avirmax, Inc. | Compositions and methods for transgene expression |
| CN117100845A (zh) * | 2022-10-24 | 2023-11-24 | 景泽生物医药(合肥)股份有限公司 | 重组人奥克纤溶酶在制备治疗脉络膜血管疾病药物中的用途 |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| JP3957765B2 (ja) | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗ｖｅｇｆ抗体 |
| JP4213224B2 (ja) | 1997-05-02 | 2009-01-21 | ジェネンテック，インコーポレーテッド | ヘテロマルチマー及び共通成分を有する多重特異性抗体の製造方法 |
| EP3050963B1 (en) | 2005-03-31 | 2019-09-18 | Chugai Seiyaku Kabushiki Kaisha | Process for production of polypeptide by regulation of assembly |
| US8871912B2 (en) | 2006-03-24 | 2014-10-28 | Merck Patent Gmbh | Engineered heterodimeric protein domains |
| WO2007147901A1 (en) | 2006-06-22 | 2007-12-27 | Novo Nordisk A/S | Production of bispecific antibodies |
| US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
| ES2563027T3 (es) | 2008-01-07 | 2016-03-10 | Amgen Inc. | Método para fabricación de moléculas heterodímeras Fc de anticuerpos utilizando efectos de conducción electrostática |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| JP2012525149A (ja) | 2009-04-27 | 2012-10-22 | オンコメッド ファーマシューティカルズ インコーポレイテッド | ヘテロ多量体分子を作製するための方法 |
| CN102958942A (zh) | 2009-12-29 | 2013-03-06 | 新兴产品开发西雅图有限公司 | 异二聚体结合蛋白及其应用 |
| TWI426920B (zh) | 2010-03-26 | 2014-02-21 | Hoffmann La Roche | 雙專一性、雙價抗－ｖｅｇｆ／抗－ａｎｇ－２抗體 |
| US9527926B2 (en) | 2010-05-14 | 2016-12-27 | Rinat Neuroscience Corp. | Heterodimeric proteins and methods for producing and purifying them |
| PL2635607T3 (pl) | 2010-11-05 | 2020-05-18 | Zymeworks Inc. | Projekt stabilnego przeciwciała heterodimerowego z mutacjami w domenie FC |
| KR20260004598A (ko) * | 2011-01-13 | 2026-01-08 | 리제너론 파아마슈티컬스, 인크. | 혈관신생 눈 장애를 치료하기 위한 vegf 길항제의 용도 |
| US9527925B2 (en) | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| LT2794905T (lt) | 2011-12-20 | 2020-07-10 | Medimmune, Llc | Modifikuoti polipeptidai, skirti bispecifinių antikūnų karkasams |
| SI2838917T1 (sl) | 2012-04-20 | 2019-11-29 | Merus Nv | Postopki in sredstva za produkcijo heterodimernih IG-podobnih molekul |
| LT3495387T (lt) * | 2012-07-13 | 2021-11-25 | Roche Glycart Ag | Bispecifiniai anti-vegf / anti-ang-2 antikūnai ir jų panaudojimas akių kraujagyslių ligoms gydyti |
| KR102083700B1 (ko) * | 2012-08-21 | 2020-03-02 | 옵코 파마슈티칼스, 엘엘씨 | 리포좀 제제 |
| RU2687043C2 (ru) * | 2013-04-29 | 2019-05-06 | Ф. Хоффманн-Ля Рош Аг | МОДИФИЦИРОВАННЫЕ АСИММЕТРИЧНЫЕ АНТИТЕЛА, СВЯЗЫВАЮЩИЕ Fc-РЕЦЕПТОР, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| KR20150063728A (ko) | 2013-12-02 | 2015-06-10 | 삼성전자주식회사 | 항 VEGF-C/항 Ang2 이중 특이 항체 |
| TWI738632B (zh) * | 2014-11-07 | 2021-09-11 | 瑞士商諾華公司 | 穩定的含有高濃度抗vegf抗體之蛋白質溶液調配物 |
| US20160144025A1 (en) * | 2014-11-25 | 2016-05-26 | Regeneron Pharmaceuticals, Inc. | Methods and formulations for treating vascular eye diseases |
| PT3230316T (pt) * | 2014-12-11 | 2022-02-24 | Bayer Healthcare Llc | Ratamento de degenerescência macular relacionada com a idade com uma pequena lesão de neovascularização coroideia ativa |
| AR103477A1 (es) * | 2015-01-28 | 2017-05-10 | Lilly Co Eli | Compuestos de vegfa / ang2 |
| WO2017197199A1 (en) * | 2016-05-13 | 2017-11-16 | Askgene Pharma Inc. | Novel angiopoietin 2, vegf dual antagonists |
| CN109563124A (zh) * | 2016-06-17 | 2019-04-02 | 豪夫迈·罗氏有限公司 | 多特异性抗体的纯化 |
-
2019
- 2019-02-05 CN CN201980011416.4A patent/CN111699004A/zh not_active Withdrawn
- 2019-02-05 CN CN202411925146.7A patent/CN119733046A/zh active Pending
- 2019-02-05 CN CN202510108289.7A patent/CN119909169A/zh active Pending
- 2019-02-05 EP EP19703978.7A patent/EP3749359A1/en active Pending
- 2019-02-05 AU AU2019219004A patent/AU2019219004B2/en active Active
- 2019-02-05 WO PCT/EP2019/052704 patent/WO2019154776A1/en not_active Ceased
- 2019-02-05 CA CA3088355A patent/CA3088355A1/en active Pending
- 2019-02-05 KR KR1020257038946A patent/KR20250166355A/ko active Pending
- 2019-02-05 JP JP2020536578A patent/JP7005772B2/ja active Active
- 2019-02-05 IL IL276383A patent/IL276383B2/en unknown
- 2019-02-05 KR KR1020247016479A patent/KR20240093772A/ko active Pending
- 2019-02-05 SG SG11202006712XA patent/SG11202006712XA/en unknown
- 2019-02-05 MX MX2020007527A patent/MX2020007527A/es unknown
- 2019-02-05 KR KR1020207025450A patent/KR20200119274A/ko not_active Ceased
- 2019-02-05 CN CN202411926524.3A patent/CN119770646A/zh active Pending
- 2019-02-11 TW TW114116623A patent/TW202535932A/zh unknown
- 2019-02-11 TW TW113103154A patent/TWI885720B/zh active
- 2019-02-11 TW TW108104518A patent/TWI831764B/zh active
-
2020
- 2020-08-05 US US16/985,477 patent/US20210139576A1/en not_active Abandoned
-
2022
- 2022-01-05 JP JP2022000341A patent/JP7273204B2/ja active Active
-
2023
- 2023-02-09 US US18/166,996 patent/US20230416353A1/en active Pending
- 2023-04-27 JP JP2023073187A patent/JP7646727B2/ja active Active
-
2025
- 2025-08-22 AU AU2025220842A patent/AU2025220842A1/en active Pending
- 2025-08-22 AU AU2025220841A patent/AU2025220841A1/en active Pending
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