JP2022180437A5 - - Google Patents
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- Publication number
- JP2022180437A5 JP2022180437A5 JP2022143467A JP2022143467A JP2022180437A5 JP 2022180437 A5 JP2022180437 A5 JP 2022180437A5 JP 2022143467 A JP2022143467 A JP 2022143467A JP 2022143467 A JP2022143467 A JP 2022143467A JP 2022180437 A5 JP2022180437 A5 JP 2022180437A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hom
- monocytes
- inhibitor
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 5
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 210000004443 dendritic cell Anatomy 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 210000002540 macrophage Anatomy 0.000 claims 2
- 210000001616 monocyte Anatomy 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000007917 intracranial administration Methods 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024153550A JP2024170560A (ja) | 2016-02-04 | 2024-09-06 | 炎症性障害の治療及び診断 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662291271P | 2016-02-04 | 2016-02-04 | |
| US62/291,271 | 2016-02-04 | ||
| PCT/US2017/015775 WO2017136322A1 (en) | 2016-02-04 | 2017-01-31 | Treatment and diagnosis of inflammatory disorders |
| JP2018560436A JP2019512018A (ja) | 2016-02-04 | 2017-01-31 | 炎症性障害の治療及び診断 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560436A Division JP2019512018A (ja) | 2016-02-04 | 2017-01-31 | 炎症性障害の治療及び診断 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024153550A Division JP2024170560A (ja) | 2016-02-04 | 2024-09-06 | 炎症性障害の治療及び診断 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022180437A JP2022180437A (ja) | 2022-12-06 |
| JP2022180437A5 true JP2022180437A5 (enExample) | 2023-03-07 |
| JP7635939B2 JP7635939B2 (ja) | 2025-02-26 |
Family
ID=59499992
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560436A Pending JP2019512018A (ja) | 2016-02-04 | 2017-01-31 | 炎症性障害の治療及び診断 |
| JP2022143467A Active JP7635939B2 (ja) | 2016-02-04 | 2022-09-09 | 炎症性障害の治療及び診断 |
| JP2024153550A Pending JP2024170560A (ja) | 2016-02-04 | 2024-09-06 | 炎症性障害の治療及び診断 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560436A Pending JP2019512018A (ja) | 2016-02-04 | 2017-01-31 | 炎症性障害の治療及び診断 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024153550A Pending JP2024170560A (ja) | 2016-02-04 | 2024-09-06 | 炎症性障害の治療及び診断 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11268095B2 (enExample) |
| EP (1) | EP3411479A4 (enExample) |
| JP (3) | JP2019512018A (enExample) |
| KR (1) | KR20180109985A (enExample) |
| CN (1) | CN108779461A (enExample) |
| AU (2) | AU2017213744B2 (enExample) |
| CA (1) | CA3013898A1 (enExample) |
| CL (3) | CL2018002097A1 (enExample) |
| IL (2) | IL311968A (enExample) |
| MX (2) | MX2018009542A (enExample) |
| MY (2) | MY194135A (enExample) |
| SG (2) | SG10201913129QA (enExample) |
| WO (1) | WO2017136322A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201913129QA (en) | 2016-02-04 | 2020-02-27 | Zhenglun Zhu | Treatment and diagnosis of inflammatory disorders |
| JP2022526671A (ja) | 2019-04-11 | 2022-05-25 | エンクリアー セラピーズ， インク． | 脳脊髄液の改善の方法ならびにそのためのデバイスおよびシステム |
| CN111528842B (zh) * | 2020-05-26 | 2023-01-03 | 复嶂环洲生物科技(上海)有限公司 | 基于生理和行为指标的帕金森病症状定量化评估方法 |
| AU2021355470A1 (en) | 2020-09-29 | 2023-06-01 | Enclear Therapies, Inc. | Subarachnoid fluid management method and system |
| WO2022271938A1 (en) * | 2021-06-23 | 2022-12-29 | Enclear Therapies, Inc. | Method of regulating gene expression |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2709309B1 (fr) | 1993-08-25 | 1995-11-10 | Centre Nat Rech Scient | Compositions cellulaires, préparation et utilisations thérapeutiques. |
| US5583153A (en) | 1994-10-06 | 1996-12-10 | Regents Of The University Of California | Use of taxol in the treatment of rheumatoid arthritis |
| US20030035790A1 (en) | 1999-01-15 | 2003-02-20 | Shu-Hsia Chen | Combination therapy for the prevention or treatment of cancer, inflammatory disorders or infectious diseases in a subject |
| EP1222933A1 (en) | 2001-01-15 | 2002-07-17 | Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum | Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| JP2006519008A (ja) | 2003-02-10 | 2006-08-24 | 独立行政法人産業技術総合研究所 | 哺乳動物細胞の調節 |
| JPWO2005070964A1 (ja) | 2004-01-27 | 2008-01-17 | 株式会社医学生物学研究所 | 単球の単離方法 |
| EP1864134A4 (en) | 2005-02-07 | 2010-10-20 | Univ Columbia | METHOD FOR TREATING OR PREVENTING HORMONRESISTENT PROSTATE CANCER USING PROTOCADHERINE PC SPECIFIC SIRNA OR OTHER INHIBITORS OF PROTOCADHERINE PC EXPRESSION OR ACTIVITY |
| EP1948680A4 (en) | 2005-10-28 | 2010-01-13 | Univ California | METHOD AND COMPOUNDS FOR DETECTING AND ISOLATING LYMPHOMA CELLS |
| EP2021499A4 (en) | 2005-12-16 | 2010-02-17 | Univ Leland Stanford Junior | FUNCTIONAL ARRAYS FOR THE IDENTIFICATION OF ELEMENTS FOR GENE PRESSION REGULATION WITH HIGH THROUGHPUT |
| US20070161031A1 (en) | 2005-12-16 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Functional arrays for high throughput characterization of gene expression regulatory elements |
| CN107446033B (zh) | 2006-02-22 | 2022-04-01 | 朱正崙 | 发育相关疾病的治疗 |
| US8741865B2 (en) * | 2009-07-15 | 2014-06-03 | Zhenglun Zhu | Treatment of immune disorders with Hom-1 inhibitors |
| WO2012071513A2 (en) * | 2010-11-24 | 2012-05-31 | Hong Gao | Expanding hematopoietic stem cells |
| US10066272B2 (en) * | 2011-06-10 | 2018-09-04 | Zhenglun Zhu | Human homeobox gene ventx and macrophage terminal differentiation and activation, compositions and methods thereof |
| WO2014093773A1 (en) | 2012-12-14 | 2014-06-19 | The Brigham And Women's Hospital, Inc. | Methods and assays relating to macrophage differentiation |
| EP3872169A1 (en) * | 2013-04-10 | 2021-09-01 | Zhenglun Zhu | Homeobox transcription factor ventx regulates differentiation and maturation of human dendritic cells |
| US9428748B2 (en) * | 2013-06-17 | 2016-08-30 | Hong Gao | Method of expanding hematopoietic stem cells |
| WO2017044487A1 (en) | 2015-09-09 | 2017-03-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Genetic engineering of macrophages for immunotherapy |
| JP7191377B2 (ja) | 2015-11-11 | 2022-12-19 | ジェンルン ジュー | マクロファージの分化及び免疫を改変する方法 |
| SG10201913129QA (en) | 2016-02-04 | 2020-02-27 | Zhenglun Zhu | Treatment and diagnosis of inflammatory disorders |
| JP7289289B2 (ja) | 2017-03-28 | 2023-06-09 | ツェンラン・チュー | 腫瘍性疾患を治療する方法 |
-
2017
- 2017-01-31 SG SG10201913129QA patent/SG10201913129QA/en unknown
- 2017-01-31 KR KR1020187025087A patent/KR20180109985A/ko not_active Ceased
- 2017-01-31 IL IL311968A patent/IL311968A/en unknown
- 2017-01-31 MX MX2018009542A patent/MX2018009542A/es unknown
- 2017-01-31 AU AU2017213744A patent/AU2017213744B2/en active Active
- 2017-01-31 EP EP17748003.5A patent/EP3411479A4/en active Pending
- 2017-01-31 IL IL260987A patent/IL260987B2/en unknown
- 2017-01-31 JP JP2018560436A patent/JP2019512018A/ja active Pending
- 2017-01-31 CA CA3013898A patent/CA3013898A1/en active Pending
- 2017-01-31 MY MYPI2018702738A patent/MY194135A/en unknown
- 2017-01-31 CN CN201780016917.2A patent/CN108779461A/zh active Pending
- 2017-01-31 SG SG11201806636SA patent/SG11201806636SA/en unknown
- 2017-01-31 WO PCT/US2017/015775 patent/WO2017136322A1/en not_active Ceased
- 2017-01-31 US US16/075,479 patent/US11268095B2/en active Active
- 2017-01-31 MY MYPI2021007385A patent/MY203831A/en unknown
-
2018
- 2018-08-03 MX MX2022010890A patent/MX2022010890A/es unknown
- 2018-08-03 CL CL2018002097A patent/CL2018002097A1/es unknown
-
2021
- 2021-12-29 CL CL2021003543A patent/CL2021003543A1/es unknown
-
2022
- 2022-02-18 US US17/675,800 patent/US12146138B2/en active Active
- 2022-09-09 JP JP2022143467A patent/JP7635939B2/ja active Active
-
2023
- 2023-09-22 AU AU2023233180A patent/AU2023233180A1/en active Pending
- 2023-10-06 CL CL2023003003A patent/CL2023003003A1/es unknown
-
2024
- 2024-09-06 JP JP2024153550A patent/JP2024170560A/ja active Pending
- 2024-10-17 US US18/918,938 patent/US20250188474A1/en active Pending
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