JP2022176933A5 - - Google Patents
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- Publication number
- JP2022176933A5 JP2022176933A5 JP2022119504A JP2022119504A JP2022176933A5 JP 2022176933 A5 JP2022176933 A5 JP 2022176933A5 JP 2022119504 A JP2022119504 A JP 2022119504A JP 2022119504 A JP2022119504 A JP 2022119504A JP 2022176933 A5 JP2022176933 A5 JP 2022176933A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- toxin
- binder
- fusion protein
- protoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19157839.2 | 2019-02-18 | ||
| EP19157839 | 2019-02-18 | ||
| JP2021548219A JP7150999B2 (ja) | 2019-02-18 | 2020-02-18 | 植物細胞または植物全体においてバインダー‐毒素融合タンパク質を産生する方法 |
| PCT/EP2020/054263 WO2020169620A1 (en) | 2019-02-18 | 2020-02-18 | Method of producing a binder-toxin fusion protein in a plant cell or a whole plant |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021548219A Division JP7150999B2 (ja) | 2019-02-18 | 2020-02-18 | 植物細胞または植物全体においてバインダー‐毒素融合タンパク質を産生する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022176933A JP2022176933A (ja) | 2022-11-30 |
| JP2022176933A5 true JP2022176933A5 (enExample) | 2023-02-09 |
| JP7728587B2 JP7728587B2 (ja) | 2025-08-25 |
Family
ID=65717705
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021548219A Active JP7150999B2 (ja) | 2019-02-18 | 2020-02-18 | 植物細胞または植物全体においてバインダー‐毒素融合タンパク質を産生する方法 |
| JP2022119504A Active JP7728587B2 (ja) | 2019-02-18 | 2022-07-27 | 植物細胞または植物全体においてバインダー‐毒素融合タンパク質を産生する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021548219A Active JP7150999B2 (ja) | 2019-02-18 | 2020-02-18 | 植物細胞または植物全体においてバインダー‐毒素融合タンパク質を産生する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220090113A1 (enExample) |
| EP (2) | EP4733324A2 (enExample) |
| JP (2) | JP7150999B2 (enExample) |
| KR (1) | KR102398485B1 (enExample) |
| CN (2) | CN115925972A (enExample) |
| BR (1) | BR112021016348A2 (enExample) |
| CA (1) | CA3128793C (enExample) |
| ES (1) | ES3055338T3 (enExample) |
| IL (1) | IL285719B (enExample) |
| WO (1) | WO2020169620A1 (enExample) |
| ZA (1) | ZA202105654B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115925972A (zh) * | 2019-02-18 | 2023-04-07 | Atb治疗公司 | 在植物细胞或整株植物中产生结合物-毒素融合蛋白的方法 |
| CN115768897B (zh) * | 2020-05-28 | 2026-03-27 | 中外制药株式会社 | 改进的颗粒酶b变体 |
| JP7818834B2 (ja) | 2020-08-17 | 2026-02-24 | エーティービー セラピューティクス | リボトキシンまたはＲＮＡｓｅを含む組換え免疫毒素 |
| EP4328243A4 (en) * | 2021-04-20 | 2025-05-21 | Korea University Research and Business Foundation | Asymmetric antibody with improved cytotoxicity against cancer cell |
| IL314969A (en) | 2022-02-17 | 2024-10-01 | Atb Therapeutics | Recombinant immunotoxin comprising a ribosome inactivating protein |
| CN114605556B (zh) * | 2022-03-10 | 2023-04-14 | 南开大学 | 一种增强植物根系募集功能细菌的融合蛋白及其制备方法和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US6140075A (en) | 1994-07-25 | 2000-10-31 | Monsanto Company | Method for producing antibodies and protein toxins in plant cells |
| ES2176484T3 (es) | 1995-08-18 | 2002-12-01 | Morphosys Ag | Bancos de proteinas/(poli)peptidos. |
| WO2003007889A2 (en) * | 2001-07-17 | 2003-01-30 | Research Development Foundation | Therapeutic agents comprising pro-apoptotic proteins |
| US7053202B2 (en) | 2001-10-19 | 2006-05-30 | Millennium Pharmaceuticals, Inc. | Immunoglobulin DNA cassette molecules, monobody constructs, methods of production, and methods of use therefor |
| US20040132101A1 (en) * | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| WO2003073843A2 (en) | 2002-03-05 | 2003-09-12 | Artemis Pharmaceuticals Gmbh | Inbred embryonic stem-cell derived mice |
| JP2006507800A (ja) | 2002-06-07 | 2006-03-09 | ラージ・スケール・バイオロジー・コーポレイション | 可撓性ワクチンアセンブリおよびワクチン送達プラットフォーム |
| TW200732350A (en) | 2005-10-21 | 2007-09-01 | Amgen Inc | Methods for generating monovalent IgG |
| CA2705289A1 (en) * | 2007-11-13 | 2009-05-22 | The Scripps Research Institute | Production of cytotoxic antibody-toxin fusion in eukaryotic algae |
| EP2113255A1 (en) * | 2008-05-02 | 2009-11-04 | f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. | Cytotoxic immunoglobulin |
| US9586996B2 (en) * | 2010-04-30 | 2017-03-07 | Esperance Pharmaceuticals, Inc. | Lytic-peptide-Her2/neu (human epidermal growth factor receptor 2) ligand conjugates and methods of use |
| US20130145502A1 (en) | 2010-06-09 | 2013-06-06 | Pioneer Hi-Bred International, Inc. | Regulatory sequences for modulating transgene expression in plants |
| EP3666795A1 (en) | 2013-03-12 | 2020-06-17 | Molecular Templates, Inc. | Cytotoxic proteins comprising cell-targeting binding regions and shiga toxin a subunit regions for selective killing of specific cell types |
| WO2016187585A1 (en) * | 2015-05-20 | 2016-11-24 | Viventia Bio Inc. | Deimmunized linker and methods of use |
| CN105753986B (zh) * | 2016-04-24 | 2019-12-10 | 赵磊 | 一类抗cd20靶向抗体及用途 |
| CN115925972A (zh) * | 2019-02-18 | 2023-04-07 | Atb治疗公司 | 在植物细胞或整株植物中产生结合物-毒素融合蛋白的方法 |
-
2020
- 2020-02-18 CN CN202210858173.1A patent/CN115925972A/zh active Pending
- 2020-02-18 KR KR1020217027132A patent/KR102398485B1/ko active Active
- 2020-02-18 BR BR112021016348A patent/BR112021016348A2/pt unknown
- 2020-02-18 EP EP25209159.0A patent/EP4733324A2/en active Pending
- 2020-02-18 CA CA3128793A patent/CA3128793C/en active Active
- 2020-02-18 CN CN202080029119.5A patent/CN113728107B/zh active Active
- 2020-02-18 EP EP20704343.1A patent/EP3927831B1/en active Active
- 2020-02-18 US US17/431,374 patent/US20220090113A1/en active Pending
- 2020-02-18 IL IL285719A patent/IL285719B/en unknown
- 2020-02-18 JP JP2021548219A patent/JP7150999B2/ja active Active
- 2020-02-18 WO PCT/EP2020/054263 patent/WO2020169620A1/en not_active Ceased
- 2020-02-18 ES ES20704343T patent/ES3055338T3/es active Active
-
2021
- 2021-08-05 ZA ZA2021/05654A patent/ZA202105654B/en unknown
-
2022
- 2022-07-27 JP JP2022119504A patent/JP7728587B2/ja active Active
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