JP2023538563A5 - - Google Patents

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Publication number
JP2023538563A5
JP2023538563A5 JP2023511894A JP2023511894A JP2023538563A5 JP 2023538563 A5 JP2023538563 A5 JP 2023538563A5 JP 2023511894 A JP2023511894 A JP 2023511894A JP 2023511894 A JP2023511894 A JP 2023511894A JP 2023538563 A5 JP2023538563 A5 JP 2023538563A5
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JP
Japan
Prior art keywords
binder
fusion protein
rnase
toxin fusion
toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023511894A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023538563A (ja
JP7818834B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/072859 external-priority patent/WO2022038152A1/en
Publication of JP2023538563A publication Critical patent/JP2023538563A/ja
Publication of JP2023538563A5 publication Critical patent/JP2023538563A5/ja
Application granted granted Critical
Publication of JP7818834B2 publication Critical patent/JP7818834B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023511894A 2020-08-17 2021-08-17 リボトキシンまたはRNAseを含む組換え免疫毒素 Active JP7818834B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP20191419 2020-08-17
EP20191417 2020-08-17
EP20191419.9 2020-08-17
EP20191417.3 2020-08-17
EP21156276.4 2021-02-10
EP21156276 2021-02-10
EP21156837.3 2021-02-12
EP21156837 2021-02-12
EP21186435 2021-07-19
EP21186435.0 2021-07-19
PCT/EP2021/072859 WO2022038152A1 (en) 2020-08-17 2021-08-17 Recombinant immunotoxin comprising a ribotoxin or rnase

Publications (3)

Publication Number Publication Date
JP2023538563A JP2023538563A (ja) 2023-09-08
JP2023538563A5 true JP2023538563A5 (enExample) 2024-08-26
JP7818834B2 JP7818834B2 (ja) 2026-02-24

Family

ID=80350379

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023511894A Active JP7818834B2 (ja) 2020-08-17 2021-08-17 リボトキシンまたはRNAseを含む組換え免疫毒素

Country Status (8)

Country Link
US (1) US20230310557A1 (enExample)
EP (1) EP4196593A1 (enExample)
JP (1) JP7818834B2 (enExample)
KR (1) KR20230048435A (enExample)
CN (1) CN116390947A (enExample)
CA (1) CA3187245A1 (enExample)
IL (1) IL300701A (enExample)
WO (1) WO2022038152A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4568997A1 (en) * 2022-08-08 2025-06-18 ATB Therapeutics Humanized antibodies against cd79b

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US6548640B1 (en) 1986-03-27 2003-04-15 Btg International Limited Altered antibodies
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6140075A (en) 1994-07-25 2000-10-31 Monsanto Company Method for producing antibodies and protein toxins in plant cells
ES2176484T3 (es) 1995-08-18 2002-12-01 Morphosys Ag Bancos de proteinas/(poli)peptidos.
US7053202B2 (en) 2001-10-19 2006-05-30 Millennium Pharmaceuticals, Inc. Immunoglobulin DNA cassette molecules, monobody constructs, methods of production, and methods of use therefor
WO2003068821A2 (en) * 2002-02-14 2003-08-21 Immunomedics, Inc. Anti-cd20 antibodies and fusion proteins thereof and methods of use
WO2003073843A2 (en) 2002-03-05 2003-09-12 Artemis Pharmaceuticals Gmbh Inbred embryonic stem-cell derived mice
US20120276100A1 (en) * 2005-04-06 2012-11-01 Ibc Pharmaceuticals, Inc. Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity
TW200732350A (en) 2005-10-21 2007-09-01 Amgen Inc Methods for generating monovalent IgG
PE20090943A1 (es) 2007-07-16 2009-08-05 Genentech Inc Anticuerpos anti-cd79b e inmunoconjugados
KR101607346B1 (ko) * 2008-01-31 2016-03-29 제넨테크, 인크. 항-cd79b 항체 및 면역접합체 및 사용 방법
US20130145502A1 (en) 2010-06-09 2013-06-06 Pioneer Hi-Bred International, Inc. Regulatory sequences for modulating transgene expression in plants
PL397167A1 (pl) * 2011-11-28 2013-06-10 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe bialko fuzyjne
PL2971038T3 (pl) * 2013-03-14 2020-04-30 Research Corporation Technologies, Inc. Cząsteczki rybotoksyny pochodzące z sarcyny i inne powiązane grzybowe rybotoksyny
US20160304617A1 (en) * 2013-06-17 2016-10-20 Asana Biosciences, Llc 5t4-targeted immunofusion molecule and methods
EP3155006B1 (en) * 2014-06-13 2019-08-07 University of Cape Town Human cytolytic fusion proteins
CN107428840A (zh) * 2015-03-25 2017-12-01 弗劳恩霍夫应用研究促进协会 抗cd89细胞毒素的复合物
WO2017053290A1 (en) * 2015-09-23 2017-03-30 Research Corporation Technologies, Inc. Ribotoxin molecules derived from sarcin and other related fungal ribotoxins
CN115925972A (zh) 2019-02-18 2023-04-07 Atb治疗公司 在植物细胞或整株植物中产生结合物-毒素融合蛋白的方法

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