JP2022141640A5 - - Google Patents
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- JP2022141640A5 JP2022141640A5 JP2022096962A JP2022096962A JP2022141640A5 JP 2022141640 A5 JP2022141640 A5 JP 2022141640A5 JP 2022096962 A JP2022096962 A JP 2022096962A JP 2022096962 A JP2022096962 A JP 2022096962A JP 2022141640 A5 JP2022141640 A5 JP 2022141640A5
- Authority
- JP
- Japan
- Prior art keywords
- treatment
- peptide
- seq
- digested
- protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005910A JP7758766B2 (ja) | 2015-12-15 | 2024-01-18 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| JP2025171142A JP2025188193A (ja) | 2015-12-15 | 2025-10-09 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562267734P | 2015-12-15 | 2015-12-15 | |
| US62/267,734 | 2015-12-15 | ||
| JP2018531159A JP7092669B2 (ja) | 2015-12-15 | 2016-12-15 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| PCT/US2016/066936 WO2017106504A1 (en) | 2015-12-15 | 2016-12-15 | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531159A Division JP7092669B2 (ja) | 2015-12-15 | 2016-12-15 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005910A Division JP7758766B2 (ja) | 2015-12-15 | 2024-01-18 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022141640A JP2022141640A (ja) | 2022-09-29 |
| JP2022141640A5 true JP2022141640A5 (https=) | 2023-06-16 |
| JP7425117B2 JP7425117B2 (ja) | 2024-01-30 |
Family
ID=57794352
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531159A Active JP7092669B2 (ja) | 2015-12-15 | 2016-12-15 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| JP2022096962A Active JP7425117B2 (ja) | 2015-12-15 | 2022-06-16 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| JP2024005910A Active JP7758766B2 (ja) | 2015-12-15 | 2024-01-18 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| JP2025171142A Pending JP2025188193A (ja) | 2015-12-15 | 2025-10-09 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531159A Active JP7092669B2 (ja) | 2015-12-15 | 2016-12-15 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005910A Active JP7758766B2 (ja) | 2015-12-15 | 2024-01-18 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
| JP2025171142A Pending JP2025188193A (ja) | 2015-12-15 | 2025-10-09 | 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11668718B2 (https=) |
| EP (2) | EP3390439B1 (https=) |
| JP (4) | JP7092669B2 (https=) |
| KR (2) | KR102728491B1 (https=) |
| CN (1) | CN108602877A (https=) |
| AU (3) | AU2016372159B2 (https=) |
| CA (1) | CA3008621A1 (https=) |
| CO (1) | CO2018007216A2 (https=) |
| EA (1) | EA201891414A1 (https=) |
| IL (4) | IL312919B2 (https=) |
| MX (2) | MX2018007493A (https=) |
| NZ (1) | NZ743482A (https=) |
| WO (1) | WO2017106504A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6757252B2 (ja) | 2013-10-21 | 2020-09-16 | ダイアックス コーポレーション | 血漿カリクレイン系バイオマーカーを決定するためのアッセイ |
| CA2927695C (en) | 2013-10-21 | 2022-03-01 | Dyax Corp. | Diagnosis and treatment of autoimmune diseases |
| KR20240133761A (ko) | 2015-10-19 | 2024-09-04 | 다케다 파머수티컬 컴패니 리미티드 | 절단된 고분자량 키니노겐의 검출을 위한 면역검정법 |
| EP3390439B1 (en) | 2015-12-15 | 2025-03-12 | Takeda Pharmaceutical Company Limited | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk |
| WO2018225830A1 (ja) * | 2017-06-08 | 2018-12-13 | 国立大学法人宮崎大学 | 肺がんの検出方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047323A (en) * | 1986-01-22 | 1991-09-10 | Temple University Of The Commonwealth System Of Higher Education | Method for detecting human kininogen using monoclonal antibodies thereto |
| JP2603487B2 (ja) | 1987-11-26 | 1997-04-23 | 大日本製薬株式会社 | ガンに罹患している疑いのあるヒトをスクリーニングする方法 |
| JPH08208692A (ja) | 1994-09-28 | 1996-08-13 | Sumitomo Pharmaceut Co Ltd | 新規な細胞接着抑制ペプチド誘導体 |
| JP3073439B2 (ja) * | 1996-02-08 | 2000-08-07 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| EP1044012B1 (en) | 1998-11-10 | 2006-05-03 | Temple University of the Commonwealth System of Higher Education | Inhibition of angiogenesis by peptide analogs of high molecular weight kininogen domain 5 |
| US20060154319A1 (en) | 1999-04-29 | 2006-07-13 | Flodgaard Hans J | Inhibition of bradykinin release |
| WO2001034195A1 (en) | 1999-11-12 | 2001-05-17 | Temple University Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5 |
| CA2478962A1 (en) | 2002-03-15 | 2003-09-25 | Attenuon, Llc | Cell surface tropomyosin as a target of angiogenesis inhibition |
| CN1858243A (zh) | 2005-04-30 | 2006-11-08 | 安徽省生物医学研究所 | 一种预测血管紧张素ii受体拮抗剂类降压药药物作用的方法及其应用 |
| EP2216651A4 (en) * | 2007-10-18 | 2010-12-01 | Miyazaki Prefectural Ind Suppo | BIOMARKERS FOR THE DIAGNOSIS OF LIVER DISEASE |
| AU2009269257A1 (en) | 2008-07-07 | 2010-01-14 | Nippon Zoki Pharmaceutical Co., Ltd. | Method for detection of fibromyalgia |
| GB0821721D0 (en) | 2008-11-27 | 2008-12-31 | Hansa Medical Ab | Antimicrobial therapy |
| ES2529101T3 (es) | 2009-03-30 | 2015-02-16 | Nordic Bioscience A/S | Ensayo de biomarcadores para fibrosis |
| JP5714285B2 (ja) | 2010-09-29 | 2015-05-07 | 株式会社プロトセラ | 妊娠高血圧症候群マーカーおよびそれを用いた診断 |
| CN102558329A (zh) | 2010-12-10 | 2012-07-11 | 中国人民解放军军事医学科学院生物医学分析中心 | 一组特异性多肽及其在制备肺癌早期诊断试剂中的用途 |
| RS57413B1 (sr) | 2012-03-28 | 2018-09-28 | Sanofi Sa | Antitela za ligande bradikinin b1 receptora |
| WO2014113712A1 (en) * | 2013-01-20 | 2014-07-24 | Dyax Corp. | Evaluation and treatment of bradykinin-mediated disorders |
| JP2016188761A (ja) | 2013-08-23 | 2016-11-04 | 国立研究開発法人国立国際医療研究センター | 糖尿病腎症の発症または発症リスクの検出方法及びキット |
| JP6757252B2 (ja) | 2013-10-21 | 2020-09-16 | ダイアックス コーポレーション | 血漿カリクレイン系バイオマーカーを決定するためのアッセイ |
| WO2015120036A1 (en) * | 2014-02-04 | 2015-08-13 | University Of Virginia Patent Foundation | Compositions and methods for analysis of protein sequences and post-translational modifications |
| CN104155457B (zh) | 2014-08-22 | 2016-11-16 | 北京蛋白质组研究中心 | 一种结直肠癌相关“多肽-蛋白组合式标志物”检测试剂盒 |
| CN104345154B (zh) | 2014-08-22 | 2016-10-26 | 北京蛋白质组研究中心 | 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒 |
| WO2016081413A1 (en) * | 2014-11-17 | 2016-05-26 | The Rockefeller University | Compositions and methods for use in diagnosis of alzheimer's disease |
| EP3390439B1 (en) | 2015-12-15 | 2025-03-12 | Takeda Pharmaceutical Company Limited | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk |
-
2016
- 2016-12-15 EP EP16825947.1A patent/EP3390439B1/en active Active
- 2016-12-15 NZ NZ743482A patent/NZ743482A/en unknown
- 2016-12-15 WO PCT/US2016/066936 patent/WO2017106504A1/en not_active Ceased
- 2016-12-15 KR KR1020187020049A patent/KR102728491B1/ko active Active
- 2016-12-15 MX MX2018007493A patent/MX2018007493A/es unknown
- 2016-12-15 IL IL312919A patent/IL312919B2/en unknown
- 2016-12-15 CA CA3008621A patent/CA3008621A1/en active Pending
- 2016-12-15 EA EA201891414A patent/EA201891414A1/ru unknown
- 2016-12-15 EP EP25162494.6A patent/EP4597115A3/en active Pending
- 2016-12-15 US US16/062,734 patent/US11668718B2/en active Active
- 2016-12-15 IL IL322971A patent/IL322971A/en unknown
- 2016-12-15 KR KR1020247036874A patent/KR102874711B1/ko active Active
- 2016-12-15 AU AU2016372159A patent/AU2016372159B2/en active Active
- 2016-12-15 CN CN201680079865.9A patent/CN108602877A/zh active Pending
- 2016-12-15 JP JP2018531159A patent/JP7092669B2/ja active Active
- 2016-12-15 IL IL297850A patent/IL297850B2/en unknown
- 2016-12-15 CO CONC2018/0007216A patent/CO2018007216A2/es unknown
-
2018
- 2018-06-13 IL IL259995A patent/IL259995B2/en unknown
- 2018-06-15 MX MX2023000773A patent/MX2023000773A/es unknown
-
2022
- 2022-06-10 AU AU2022204058A patent/AU2022204058B2/en active Active
- 2022-06-16 JP JP2022096962A patent/JP7425117B2/ja active Active
-
2023
- 2023-04-28 US US18/308,813 patent/US12135329B2/en active Active
-
2024
- 2024-01-18 JP JP2024005910A patent/JP7758766B2/ja active Active
- 2024-09-24 US US18/894,192 patent/US20250172567A1/en active Pending
-
2025
- 2025-01-22 AU AU2025200412A patent/AU2025200412A1/en active Pending
- 2025-10-09 JP JP2025171142A patent/JP2025188193A/ja active Pending
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