JP2019505185A5 - - Google Patents

Download PDF

Info

Publication number
JP2019505185A5
JP2019505185A5 JP2018531159A JP2018531159A JP2019505185A5 JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5 JP 2018531159 A JP2018531159 A JP 2018531159A JP 2018531159 A JP2018531159 A JP 2018531159A JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5
Authority
JP
Japan
Prior art keywords
hmwk
sample
hae
peptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018531159A
Other languages
English (en)
Japanese (ja)
Other versions
JP7092669B2 (ja
JP2019505185A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/066936 external-priority patent/WO2017106504A1/en
Publication of JP2019505185A publication Critical patent/JP2019505185A/ja
Publication of JP2019505185A5 publication Critical patent/JP2019505185A5/ja
Priority to JP2022096962A priority Critical patent/JP7425117B2/ja
Application granted granted Critical
Publication of JP7092669B2 publication Critical patent/JP7092669B2/ja
Priority to JP2024005910A priority patent/JP7758766B2/ja
Priority to JP2025171142A priority patent/JP2025188193A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018531159A 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ Active JP7092669B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022096962A JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2024005910A JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2025171142A JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562267734P 2015-12-15 2015-12-15
US62/267,734 2015-12-15
PCT/US2016/066936 WO2017106504A1 (en) 2015-12-15 2016-12-15 Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022096962A Division JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ

Publications (3)

Publication Number Publication Date
JP2019505185A JP2019505185A (ja) 2019-02-28
JP2019505185A5 true JP2019505185A5 (https=) 2020-01-30
JP7092669B2 JP7092669B2 (ja) 2022-06-28

Family

ID=57794352

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2018531159A Active JP7092669B2 (ja) 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2025171142A Pending JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ
JP2025171142A Pending JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン（ｈｍｗｋ）と切断されたｈｍｗｋとを区別するためのペプチド定量アッセイ

Country Status (13)

Country Link
US (3) US11668718B2 (https=)
EP (2) EP3390439B1 (https=)
JP (4) JP7092669B2 (https=)
KR (2) KR102874711B1 (https=)
CN (1) CN108602877A (https=)
AU (3) AU2016372159B2 (https=)
CA (1) CA3008621A1 (https=)
CO (1) CO2018007216A2 (https=)
EA (1) EA201891414A1 (https=)
IL (4) IL297850B2 (https=)
MX (2) MX2018007493A (https=)
NZ (1) NZ743482A (https=)
WO (1) WO2017106504A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2927695C (en) 2013-10-21 2022-03-01 Dyax Corp. Diagnosis and treatment of autoimmune diseases
WO2015061183A1 (en) 2013-10-21 2015-04-30 Dyax Corp. Assays for determining plasma kallikrein system biomarkers
EP4354146B1 (en) 2015-10-19 2026-04-15 Takeda Pharmaceutical Company Limited Immunoassay for the detection of cleaved high molecular weight kininogen
KR102874711B1 (ko) 2015-12-15 2025-10-23 다케다 파머수티컬 컴패니 리미티드 전장 고분자량 키니노겐(hmwk) 및 절단된 hmwk를 구별하기 위한 펩타이드 정량화 검정법
WO2018225830A1 (ja) * 2017-06-08 2018-12-13 国立大学法人宮崎大学 肺がんの検出方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047323A (en) 1986-01-22 1991-09-10 Temple University Of The Commonwealth System Of Higher Education Method for detecting human kininogen using monoclonal antibodies thereto
JP2603487B2 (ja) 1987-11-26 1997-04-23 大日本製薬株式会社 ガンに罹患している疑いのあるヒトをスクリーニングする方法
JPH08208692A (ja) 1994-09-28 1996-08-13 Sumitomo Pharmaceut Co Ltd 新規な細胞接着抑制ペプチド誘導体
JP3073439B2 (ja) * 1996-02-08 2000-08-07 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
AU1521500A (en) 1998-11-10 2000-05-29 W. Robert Colman Inhibition of angiogenesis by peptide analogs of high molecular weight kininogendomain
US20060154319A1 (en) 1999-04-29 2006-07-13 Flodgaard Hans J Inhibition of bradykinin release
WO2001034195A1 (en) 1999-11-12 2001-05-17 Temple University Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
EP1575525A4 (en) 2002-03-15 2008-04-02 Attenuon Llc CELL SURFACE TROPOMYOSIN AS A TARGET FOR THE INHIBITION OF ANGIOGENESIS
CN1858243A (zh) 2005-04-30 2006-11-08 安徽省生物医学研究所 一种预测血管紧张素ii受体拮抗剂类降压药药物作用的方法及其应用
US8263347B2 (en) 2007-10-18 2012-09-11 Miyazaki Prefectural Industrial Support Foundation Biomarker for diagnosis of liver disease
CA2729937A1 (en) * 2008-07-07 2010-01-14 Nippon Zoki Pharmaceutical Co., Ltd. Fibromyalgia test method
GB0821721D0 (en) 2008-11-27 2008-12-31 Hansa Medical Ab Antimicrobial therapy
EP2770327B1 (en) 2009-03-30 2017-06-14 Nordic Bioscience A/S Fibrosis biomarker assay
JP5714285B2 (ja) * 2010-09-29 2015-05-07 株式会社プロトセラ 妊娠高血圧症候群マーカーおよびそれを用いた診断
CN102558329A (zh) 2010-12-10 2012-07-11 中国人民解放军军事医学科学院生物医学分析中心 一组特异性多肽及其在制备肺癌早期诊断试剂中的用途
HUE037720T2 (hu) 2012-03-28 2018-09-28 Sanofi Sa Bradikinin B1 receptor ligandumok elleni antitestek
EP4234583A3 (en) * 2013-01-20 2024-01-24 Takeda Pharmaceutical Company Limited Evaluation and treatment of bradykinin-mediated disorders
JP2016188761A (ja) 2013-08-23 2016-11-04 国立研究開発法人国立国際医療研究センター 糖尿病腎症の発症または発症リスクの検出方法及びキット
WO2015061183A1 (en) * 2013-10-21 2015-04-30 Dyax Corp. Assays for determining plasma kallikrein system biomarkers
WO2015120036A1 (en) * 2014-02-04 2015-08-13 University Of Virginia Patent Foundation Compositions and methods for analysis of protein sequences and post-translational modifications
CN104155457B (zh) 2014-08-22 2016-11-16 北京蛋白质组研究中心 一种结直肠癌相关“多肽-蛋白组合式标志物”检测试剂盒
CN104345154B (zh) 2014-08-22 2016-10-26 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
WO2016081413A1 (en) * 2014-11-17 2016-05-26 The Rockefeller University Compositions and methods for use in diagnosis of alzheimer's disease
KR102874711B1 (ko) 2015-12-15 2025-10-23 다케다 파머수티컬 컴패니 리미티드 전장 고분자량 키니노겐(hmwk) 및 절단된 hmwk를 구별하기 위한 펩타이드 정량화 검정법

Similar Documents

Publication Publication Date Title
JP2019505185A5 (https=)
Peyvandi et al. Classification of rare bleeding disorders (RBDs) based on the association between coagulant factor activity and clinical bleeding severity
Tammen et al. Peptidomic analysis of human blood specimens: comparison between plasma specimens and serum by differential peptide display
Rehak et al. The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors
JP4505045B2 (ja) 血液凝固時間の延長原因の判定法
Caires et al. Identification of a 14 kDa endocan fragment generated by cathepsin G, a novel circulating biomarker in patients with sepsis
JP2016536012A5 (https=)
AU2007247040A1 (en) Detection of venous thromboembolic diseases by measurement of D-dimers and soluble fibrin levels
US20250172567A1 (en) Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk
Aletti et al. Peptidomic analysis of rat plasma: proteolysis in hemorrhagic shock
JP2022141640A5 (https=)
da Silva Vaz Junior et al. Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding
US20100055723A1 (en) Galectin-3-Binding Protein as a Biomarker of Cardiovascular Disease
JP2024026847A5 (https=)
Serdar et al. The relation between oxidant and antioxidant parameters and severity of acute coronary syndromes
Sempere et al. Assessing the short-and long-term prognosis of patients with cirrhosis and acute variceal bleeding
Lopez-Pedrera et al. The thrombus proteome in stroke reveals a key role of the innate immune system and new insights associated with its etiology, severity, and prognosis
US20230182139A1 (en) Evacuated blood collection tubes containing protease inhibitors for the assessment of contact system activation
WO2016012864A2 (en) Biomarkers for anderson-fabry disease
Claw et al. Quantitative evolutionary proteomics of seminal fluid from primates with different mating systems
EA034043B1 (ru) Способ определения продуктов деградации пептидов из протеолитического каскада в образцах крови
Dubois et al. Dipeptidyl peptidase 9 (DPP9) from bovine testes: Identification and characterization as the short form by mass spectrometry
WO2007018511A1 (en) Lupus anticoagulant testing
NZ783522A (en) Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK
NZ783522B2 (en) Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK