JP2019505185A5 - - Google Patents

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Publication number
JP2019505185A5
JP2019505185A5 JP2018531159A JP2018531159A JP2019505185A5 JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5 JP 2018531159 A JP2018531159 A JP 2018531159A JP 2018531159 A JP2018531159 A JP 2018531159A JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5
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JP
Japan
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hmwk
sample
hae
peptide
seq
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JP2018531159A
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English (en)
Japanese (ja)
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JP2019505185A (ja
JP7092669B2 (ja
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Priority claimed from PCT/US2016/066936 external-priority patent/WO2017106504A1/en
Publication of JP2019505185A publication Critical patent/JP2019505185A/ja
Publication of JP2019505185A5 publication Critical patent/JP2019505185A5/ja
Priority to JP2022096962A priority Critical patent/JP7425117B2/ja
Application granted granted Critical
Publication of JP7092669B2 publication Critical patent/JP7092669B2/ja
Priority to JP2024005910A priority patent/JP7758766B2/ja
Priority to JP2025171142A priority patent/JP2025188193A/ja
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JP2018531159A 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ Active JP7092669B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022096962A JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2025171142A JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562267734P 2015-12-15 2015-12-15
US62/267,734 2015-12-15
PCT/US2016/066936 WO2017106504A1 (en) 2015-12-15 2016-12-15 Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022096962A Division JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Publications (3)

Publication Number Publication Date
JP2019505185A JP2019505185A (ja) 2019-02-28
JP2019505185A5 true JP2019505185A5 (https=) 2020-01-30
JP7092669B2 JP7092669B2 (ja) 2022-06-28

Family

ID=57794352

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2018531159A Active JP7092669B2 (ja) 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2025171142A Pending JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2025171142A Pending JP2025188193A (ja) 2015-12-15 2025-10-09 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Country Status (13)

Country Link
US (3) US11668718B2 (https=)
EP (2) EP3390439B1 (https=)
JP (4) JP7092669B2 (https=)
KR (2) KR102728491B1 (https=)
CN (1) CN108602877A (https=)
AU (3) AU2016372159B2 (https=)
CA (1) CA3008621A1 (https=)
CO (1) CO2018007216A2 (https=)
EA (1) EA201891414A1 (https=)
IL (4) IL312919B2 (https=)
MX (2) MX2018007493A (https=)
NZ (1) NZ743482A (https=)
WO (1) WO2017106504A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6757252B2 (ja) 2013-10-21 2020-09-16 ダイアックス コーポレーション 血漿カリクレイン系バイオマーカーを決定するためのアッセイ
CA2927695C (en) 2013-10-21 2022-03-01 Dyax Corp. Diagnosis and treatment of autoimmune diseases
KR20240133761A (ko) 2015-10-19 2024-09-04 다케다 파머수티컬 컴패니 리미티드 절단된 고분자량 키니노겐의 검출을 위한 면역검정법
EP3390439B1 (en) 2015-12-15 2025-03-12 Takeda Pharmaceutical Company Limited Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk
WO2018225830A1 (ja) * 2017-06-08 2018-12-13 国立大学法人宮崎大学 肺がんの検出方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047323A (en) * 1986-01-22 1991-09-10 Temple University Of The Commonwealth System Of Higher Education Method for detecting human kininogen using monoclonal antibodies thereto
JP2603487B2 (ja) 1987-11-26 1997-04-23 大日本製薬株式会社 ガンに罹患している疑いのあるヒトをスクリーニングする方法
JPH08208692A (ja) 1994-09-28 1996-08-13 Sumitomo Pharmaceut Co Ltd 新規な細胞接着抑制ペプチド誘導体
JP3073439B2 (ja) * 1996-02-08 2000-08-07 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
EP1044012B1 (en) 1998-11-10 2006-05-03 Temple University of the Commonwealth System of Higher Education Inhibition of angiogenesis by peptide analogs of high molecular weight kininogen domain 5
US20060154319A1 (en) 1999-04-29 2006-07-13 Flodgaard Hans J Inhibition of bradykinin release
WO2001034195A1 (en) 1999-11-12 2001-05-17 Temple University Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
CA2478962A1 (en) 2002-03-15 2003-09-25 Attenuon, Llc Cell surface tropomyosin as a target of angiogenesis inhibition
CN1858243A (zh) 2005-04-30 2006-11-08 安徽省生物医学研究所 一种预测血管紧张素ii受体拮抗剂类降压药药物作用的方法及其应用
EP2216651A4 (en) * 2007-10-18 2010-12-01 Miyazaki Prefectural Ind Suppo BIOMARKERS FOR THE DIAGNOSIS OF LIVER DISEASE
AU2009269257A1 (en) 2008-07-07 2010-01-14 Nippon Zoki Pharmaceutical Co., Ltd. Method for detection of fibromyalgia
GB0821721D0 (en) 2008-11-27 2008-12-31 Hansa Medical Ab Antimicrobial therapy
ES2529101T3 (es) 2009-03-30 2015-02-16 Nordic Bioscience A/S Ensayo de biomarcadores para fibrosis
JP5714285B2 (ja) 2010-09-29 2015-05-07 株式会社プロトセラ 妊娠高血圧症候群マーカーおよびそれを用いた診断
CN102558329A (zh) 2010-12-10 2012-07-11 中国人民解放军军事医学科学院生物医学分析中心 一组特异性多肽及其在制备肺癌早期诊断试剂中的用途
RS57413B1 (sr) 2012-03-28 2018-09-28 Sanofi Sa Antitela za ligande bradikinin b1 receptora
WO2014113712A1 (en) * 2013-01-20 2014-07-24 Dyax Corp. Evaluation and treatment of bradykinin-mediated disorders
JP2016188761A (ja) 2013-08-23 2016-11-04 国立研究開発法人国立国際医療研究センター 糖尿病腎症の発症または発症リスクの検出方法及びキット
JP6757252B2 (ja) 2013-10-21 2020-09-16 ダイアックス コーポレーション 血漿カリクレイン系バイオマーカーを決定するためのアッセイ
WO2015120036A1 (en) * 2014-02-04 2015-08-13 University Of Virginia Patent Foundation Compositions and methods for analysis of protein sequences and post-translational modifications
CN104155457B (zh) 2014-08-22 2016-11-16 北京蛋白质组研究中心 一种结直肠癌相关“多肽-蛋白组合式标志物”检测试剂盒
CN104345154B (zh) 2014-08-22 2016-10-26 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
WO2016081413A1 (en) * 2014-11-17 2016-05-26 The Rockefeller University Compositions and methods for use in diagnosis of alzheimer's disease
EP3390439B1 (en) 2015-12-15 2025-03-12 Takeda Pharmaceutical Company Limited Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk

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