|
IL104314A0
(en)
*
|
1992-01-07 |
1993-05-13 |
Novo Nordisk As |
Human kunitz-type protease inhibitor and variants thereof,their production and pharmaceutical compositions containing them
|
|
US5489508A
(en)
|
1992-05-13 |
1996-02-06 |
University Of Texas System Board Of Regents |
Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
|
|
US5643890A
(en)
|
1995-01-31 |
1997-07-01 |
The Board Of Regents Of The University Of Nebraska |
Synthetic oligonucleotides which mimic telomeric sequences for use in treatment of cancer and other diseases
|
|
ATE432348T1
(de)
*
|
1997-06-06 |
2009-06-15 |
Univ California |
Inhibitoren von immunstimulatorischen dna sequenz aktivität
|
|
US6551795B1
(en)
*
|
1998-02-18 |
2003-04-22 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
|
|
JP2002541264A
(ja)
|
1999-04-08 |
2002-12-03 |
ユーエイビー・リサーチ・ファウンデーション |
冨ｇオリゴヌクレオチドの抗増殖活性およびヌクレオリンに結合するためのその使用方法
|
|
PL354997A1
(en)
|
1999-09-25 |
2004-03-22 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acids
|
|
MXPA00011713A
(es)
*
|
2000-11-28 |
2002-05-31 |
Tgt Lab S A De C V |
Vectores recombinantes virales y no virales conteniendo el gen humano del activador de plasminogeno derivado de urocinasa y su utilidad en el tratamiento de diversos tipos de fibrosis hepatica, renal, pulmonar, pancreatica, cardiaca y cicatrices hipe
|
|
US7060690B2
(en)
|
2001-01-22 |
2006-06-13 |
Genta Incorporated |
Methods and compositions for treating a cell-proliferative disorder using CRE decoy oligomers, BCL-2 antisense oligomers, and hybrid oligomers thereof
|
|
WO2003027313A2
(en)
|
2001-09-24 |
2003-04-03 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
SUPPRESSORS OF CpG OLIGONUCLEOTIDES AND METHODS OF USE
|
|
ES2543710T3
(es)
|
2002-04-04 |
2015-08-21 |
Zoetis Belgium S.A. |
Oligorribonucleótidos inmunoestimulantes que contienen G y U
|
|
US7357928B2
(en)
|
2002-04-08 |
2008-04-15 |
University Of Louisville Research Foundation, Inc. |
Method for the diagnosis and prognosis of malignant diseases
|
|
US20040009949A1
(en)
|
2002-06-05 |
2004-01-15 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory CpG nucleic acids
|
|
EP1575504A4
(en)
|
2002-08-01 |
2009-11-04 |
Us Gov Health & Human Serv |
METHOD FOR THE TREATMENT OF INFLAMMATORY ARTHROPATHIES WITH SUPPRESSORS OF THE CPG OLIGONUCLEOTIDES
|
|
US8043622B2
(en)
|
2002-10-08 |
2011-10-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides
|
|
US7790867B2
(en)
|
2002-12-05 |
2010-09-07 |
Rosetta Genomics Inc. |
Vaccinia virus-related nucleic acids and microRNA
|
|
US20050013812A1
(en)
|
2003-07-14 |
2005-01-20 |
Dow Steven W. |
Vaccines using pattern recognition receptor-ligand:lipid complexes
|
|
US20050239733A1
(en)
|
2003-10-31 |
2005-10-27 |
Coley Pharmaceutical Gmbh |
Sequence requirements for inhibitory oligonucleotides
|
|
WO2005072097A2
(en)
|
2003-12-16 |
2005-08-11 |
University Of Massachusetts |
Toll-like receptor 9 modulators
|
|
MXPA06012915A
(es)
|
2004-05-06 |
2007-03-01 |
Gov Health & Human Serv |
Metodos y composiciones para el tratamiento de uveitis.
|
|
IL179285A
(en)
|
2004-05-14 |
2011-04-28 |
Rosetta Genomics Ltd |
Micrornas and uses thereof
|
|
WO2005116250A2
(en)
|
2004-05-26 |
2005-12-08 |
Rosetta Genomics Ltd. |
Viral and viral associated mirnas and uses thereof
|
|
KR101268877B1
(ko)
|
2004-09-01 |
2013-05-31 |
다이나박스 테크놀로지 코퍼레이션 |
선천성 면역반응 및 자가면역의 억제를 위한 방법 및조성물
|
|
JP2008000001A
(ja)
|
2004-09-30 |
2008-01-10 |
Osaka Univ |
免疫刺激オリゴヌクレオチドおよびその医薬用途
|
|
US20060193869A1
(en)
|
2004-12-17 |
2006-08-31 |
Franck Barrat |
Methods and compositions for induction or promotion of immune tolerance
|
|
US20070077231A1
(en)
*
|
2005-09-30 |
2007-04-05 |
Contag Christopher H |
Immune effector cells pre-infected with oncolytic virus
|
|
EP2341059A1
(en)
|
2005-10-12 |
2011-07-06 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
JP2009522372A
(ja)
|
2006-01-09 |
2009-06-11 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ワクチンおよび腫瘍免疫療法のためのｔｎｆｒｓｆ、ｔｌｒ、ｎｌｒ、ｒｈｒ、プリン受容体、およびサイトカイン受容体アゴニストの組み合わせ免疫刺激剤
|
|
US8298818B2
(en)
*
|
2006-04-28 |
2012-10-30 |
University Of Florida Research Foundation, Inc. |
Self-complementary adeno-associated virus having a truncated CMV-chicken β-actin promoter
|
|
EP2034833A2
(en)
|
2006-06-13 |
2009-03-18 |
Bayhill Therapeutics, Inc. |
Polynucleotide therapy
|
|
US8377898B2
(en)
|
2006-10-12 |
2013-02-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
US20110033448A1
(en)
|
2006-12-15 |
2011-02-10 |
Michel Gilliet |
Inhibitors of LL-37 Mediated Immune Reactivity to Self Nucleic Acids
|
|
AU2008220449A1
(en)
|
2007-03-01 |
2008-09-04 |
Rosetta Genomics Ltd. |
Methods for distingushing between lung squamous carcinoma and other non smallcell lung cancers
|
|
WO2009006141A2
(en)
|
2007-07-05 |
2009-01-08 |
Bausch & Lomb Incorporated |
Authority to read as follows: compositions and methods for treating or controlling infections of the eye a sequelae thereof
|
|
US7879812B2
(en)
|
2007-08-06 |
2011-02-01 |
University Of Iowa Research Foundation |
Immunomodulatory oligonucleotides and methods of use therefor
|
|
MX2010001785A
(es)
|
2007-08-15 |
2010-03-10 |
Idera Pharmaceuticals Inc |
Moduladores de receptores tipo larga distancia.
|
|
JP5749492B2
(ja)
|
2007-10-26 |
2015-07-15 |
ダイナバックス テクノロジーズ コーポレイション |
免疫応答と自己免疫を阻害する方法及び組成物
|
|
WO2009089401A2
(en)
|
2008-01-10 |
2009-07-16 |
Bausch & Lomb Incorporated |
Compositions comprising toll-like receptor or coreceptor antagonists and methods for treating or controlling ocular allergy using same
|
|
WO2009089399A2
(en)
|
2008-01-10 |
2009-07-16 |
Bausch & Lomb Incorporated |
Compositions comprising toll-like receptor or coreceptor antagonists and methods for ocular neuroprotection
|
|
WO2009143292A2
(en)
|
2008-05-21 |
2009-11-26 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating pneumoconiosis with oligodeoxynucleotides
|
|
JP5415724B2
(ja)
*
|
2008-08-05 |
2014-02-12 |
長春華普生物技術有限公司 |
一種のオリゴヌクレオチド及びその応用
|
|
US8030289B2
(en)
|
2008-08-06 |
2011-10-04 |
Changchun Huapu Biotechnology Co., Ltd. |
Oligonucleotide and use thereof
|
|
WO2010034779A2
(en)
*
|
2008-09-24 |
2010-04-01 |
The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin |
Composition and method for treatment of preterm labor
|
|
GB0906130D0
(en)
|
2008-10-03 |
2009-05-20 |
Procrata Biosystems Ltd |
Transcription factor decoys
|
|
EP2349271A2
(en)
|
2008-10-06 |
2011-08-03 |
Idera Pharmaceuticals, Inc. |
Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto
|
|
US8053422B2
(en)
|
2008-12-04 |
2011-11-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-cancer oligodeoxynucleotides
|
|
WO2010108035A1
(en)
*
|
2009-03-18 |
2010-09-23 |
Isis Pharmaceuticals, Inc. |
Compounds and methods for modulating toxic and proinflammatory effects
|
|
US8728458B2
(en)
|
2009-04-30 |
2014-05-20 |
The Regents Of The University Of California |
Combination anti-HIV vectors, targeting vectors, and methods of use
|
|
ES2624767T3
(es)
|
2009-06-01 |
2017-07-17 |
Idera Pharmaceuticals, Inc |
Potenciación de tratamientos de enfermedades autoinmunitarias e inflamatorias mediante oligonucleótidos inmunorreguladores (IRO) antagonistas de TLR7 y TLR9
|
|
US20110070241A1
(en)
|
2009-06-30 |
2011-03-24 |
Duke University |
Methods for modulating immune responses to aav gene therapy vectors
|
|
WO2011005942A2
(en)
|
2009-07-08 |
2011-01-13 |
Idera Pharmaceuticals, Inc. |
Oligonucleotide-based compounds as inhibitors of toll-like receptors
|
|
CN101712957B
(zh)
*
|
2009-11-25 |
2011-11-23 |
中国人民解放军第三军医大学第一附属医院 |
Toll样受体9阻断剂及应用
|
|
US8771669B1
(en)
|
2010-02-09 |
2014-07-08 |
David Gordon Bermudes |
Immunization and/or treatment of parasites and infectious agents by live bacteria
|
|
US9272053B2
(en)
|
2010-04-23 |
2016-03-01 |
University Of Massachusetts |
AAV-based treatment of cholesterol-related disorders
|
|
WO2011159328A1
(en)
|
2010-06-16 |
2011-12-22 |
Dynavax Technologies Corporation |
Methods of treatment using tlr7 and/or tlr9 inhibitors
|
|
BR112012032240A2
(pt)
|
2010-06-16 |
2019-09-24 |
Dynavax Technologies Corporation |
método de tratamento utilizando inibidores tlr7 e/ou tlr9
|
|
GB201014026D0
(en)
|
2010-08-20 |
2010-10-06 |
Ucl Business Plc |
Treatment
|
|
WO2012051491A1
(en)
*
|
2010-10-14 |
2012-04-19 |
The United States Of America, As Represented By The Secretary National Institutes Of Health |
Compositions and methods for controlling neurotropic viral pathogenesis by micro-rna targeting
|
|
US8486908B2
(en)
|
2010-11-19 |
2013-07-16 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
US20140378531A1
(en)
|
2012-02-01 |
2014-12-25 |
New York University |
Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors
|
|
AR091569A1
(es)
|
2012-06-28 |
2015-02-11 |
Intervet Int Bv |
Receptores de tipo toll
|
|
EP3738974A1
(en)
|
2012-09-28 |
2020-11-18 |
The University of North Carolina at Chapel Hill |
Aav vectors targeted to oligodendrocytes
|
|
CN102925485B
(zh)
|
2012-11-09 |
2014-07-09 |
中国农业科学院兰州兽医研究所 |
双表达的aav重组病毒的制备方法
|
|
JP6106280B2
(ja)
*
|
2012-11-29 |
2017-03-29 |
Ｓｂｉバイオテック株式会社 |
阻害性オリゴヌクレオチド及びその使用
|
|
US9453209B2
(en)
*
|
2012-12-27 |
2016-09-27 |
Sierra Sciences, Llc |
Enhancing health in mammals using telomerase reverse transcriptase gene therapy
|
|
EP2943251B1
(en)
|
2013-01-08 |
2018-10-10 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
|
|
US20140271550A1
(en)
|
2013-03-14 |
2014-09-18 |
The Trustees Of The University Of Pennsylvania |
Constructs and Methods for Delivering Molecules via Viral Vectors with Blunted Innate Immune Responses
|
|
US20170035864A1
(en)
|
2013-12-09 |
2017-02-09 |
Bullet Biotechnology, Inc. |
SPECIFIC VIRUS-LIKE PARTICLE-CpG OLIGONUCLEOTIDE VACCINES AND USES THEREOF
|
|
CA2974651A1
(en)
|
2014-01-24 |
2015-07-30 |
Children's Hospital Of Eastern Ontario Research Institute Inc. |
Smc combination therapy for the treatment of cancer
|
|
US12139542B2
(en)
|
2014-05-27 |
2024-11-12 |
Trustees Of Boston University |
Inhibitors of aortic carboxypeptidase-like protein (ACLP)
|
|
EP2982756A1
(en)
|
2014-08-04 |
2016-02-10 |
Berlin Cures Holding AG |
Aptamers for use against autoantibody-associated diseases
|
|
US20170333565A1
(en)
|
2014-10-31 |
2017-11-23 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Tlr9 targeted cytotoxic agents
|
|
WO2016130832A1
(en)
|
2015-02-13 |
2016-08-18 |
Idera Pharmaceuticals, Inc. |
Toll-like receptor 9 antagonist and methods of use thereof
|
|
US11156599B2
(en)
|
2015-03-19 |
2021-10-26 |
The Johns Hopkins University |
Assay for telomere length regulators
|
|
US10775367B2
(en)
|
2015-04-15 |
2020-09-15 |
Ji Hoon Lee |
Aptasensor and method of detecting target material
|
|
WO2016183370A1
(en)
|
2015-05-13 |
2016-11-17 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Synthetic immunosuppressive oligodeoxynucleotides reduce ischemic tissue damage
|
|
DK3329004T3
(da)
|
2015-07-29 |
2020-04-20 |
Ifom Fondazione St Firc Di Oncologia Molecolare |
Terapeutiske oligonukleotider
|
|
EP3377095B1
(en)
|
2015-11-18 |
2020-01-01 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for treating rhabdomyolysis
|
|
EP3394263B1
(en)
|
2015-12-25 |
2025-02-26 |
SBI Biotech Co., Ltd. |
Tlr inhibitory oligonucleotides and their use
|
|
CN105597079A
(zh)
*
|
2016-01-11 |
2016-05-25 |
中国人民解放军第三军医大学第一附属医院 |
用于治疗银屑病的药物
|
|
US10124062B2
(en)
|
2016-02-26 |
2018-11-13 |
The United States Of America As Represented By The Department Of Veterans Affairs |
Methods of treating, inhibiting and/or preventing an auditory impairment
|
|
KR20190017872A
(ko)
|
2016-06-08 |
2019-02-20 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
염증 및 면역 반응 유도를 감소시키는 조작된 바이러스 벡터
|
|
US10947545B2
(en)
|
2016-11-23 |
2021-03-16 |
Berlin Cures GmbH |
Aptamers for use in inhibition and/or suppression of TLR9 activation
|
|
KR20200085812A
(ko)
|
2017-11-08 |
2020-07-15 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
바이러스 벡터-유도된 염증 반응을 억제하기 위한 조성물 및 방법
|