JP2019522461A5 - - Google Patents

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JP2019522461A5
JP2019522461A5 JP2018558287A JP2018558287A JP2019522461A5 JP 2019522461 A5 JP2019522461 A5 JP 2019522461A5 JP 2018558287 A JP2018558287 A JP 2018558287A JP 2018558287 A JP2018558287 A JP 2018558287A JP 2019522461 A5 JP2019522461 A5 JP 2019522461A5
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JP
Japan
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seq
grna molecule
set forth
nucleotide sequence
sequence set
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JP2018558287A
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English (en)
Japanese (ja)
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JP2019522461A (ja
JP7075597B2 (ja
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Priority claimed from PCT/US2017/031351 external-priority patent/WO2017193029A2/en
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Publication of JP2019522461A5 publication Critical patent/JP2019522461A5/ja
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JP2018558287A 2016-05-05 2017-05-05 デュシェンヌ型筋ジストロフィーを治療するためのcrispr/cas関連の方法および組成物 Active JP7075597B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332297P 2016-05-05 2016-05-05
US62/332,297 2016-05-05
PCT/US2017/031351 WO2017193029A2 (en) 2016-05-05 2017-05-05 Crispr/cas-related methods and compositions for treating duchenne muscular dystrophy

Publications (3)

Publication Number Publication Date
JP2019522461A JP2019522461A (ja) 2019-08-15
JP2019522461A5 true JP2019522461A5 (OSRAM) 2020-06-25
JP7075597B2 JP7075597B2 (ja) 2022-05-26

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JP2018558287A Active JP7075597B2 (ja) 2016-05-05 2017-05-05 デュシェンヌ型筋ジストロフィーを治療するためのcrispr/cas関連の方法および組成物

Country Status (5)

Country Link
US (1) US20190134221A1 (OSRAM)
EP (1) EP3452498B1 (OSRAM)
JP (1) JP7075597B2 (OSRAM)
ES (1) ES2957660T3 (OSRAM)
WO (1) WO2017193029A2 (OSRAM)

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US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
US9388430B2 (en) 2013-09-06 2016-07-12 President And Fellows Of Harvard College Cas9-recombinase fusion proteins and uses thereof
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US9737604B2 (en) 2013-09-06 2017-08-22 President And Fellows Of Harvard College Use of cationic lipids to deliver CAS9
US11053481B2 (en) 2013-12-12 2021-07-06 President And Fellows Of Harvard College Fusions of Cas9 domains and nucleic acid-editing domains
AU2015298571B2 (en) 2014-07-30 2020-09-03 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
WO2016130600A2 (en) 2015-02-09 2016-08-18 Duke University Compositions and methods for epigenome editing
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WO2017066497A2 (en) 2015-10-13 2017-04-20 Duke University Genome engineering with type i crispr systems in eukaryotic cells
US12043852B2 (en) 2015-10-23 2024-07-23 President And Fellows Of Harvard College Evolved Cas9 proteins for gene editing
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US20190127713A1 (en) 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
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US11268082B2 (en) 2017-03-23 2022-03-08 President And Fellows Of Harvard College Nucleobase editors comprising nucleic acid programmable DNA binding proteins
WO2018209320A1 (en) 2017-05-12 2018-11-15 President And Fellows Of Harvard College Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
JP2020534795A (ja) 2017-07-28 2020-12-03 プレジデント アンド フェローズ オブ ハーバード カレッジ ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
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AU2019216321A1 (en) * 2018-01-31 2020-07-30 The Board Of Regents Of The University Of Texas System Compositions and methods for correcting dystrophin mutations in human cardiomyocytes
WO2019209777A1 (en) * 2018-04-23 2019-10-31 The Curators Of The University Of Missouri Improved crispr therapy
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US20210047649A1 (en) * 2019-05-08 2021-02-18 Vertex Pharmaceuticals Incorporated Crispr/cas all-in-two vector systems for treatment of dmd
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