JP2022058682A5 - - Google Patents
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- JP2022058682A5 JP2022058682A5 JP2022007043A JP2022007043A JP2022058682A5 JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5 JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5
- Authority
- JP
- Japan
- Prior art keywords
- synergistic combination
- gram
- composition
- amino acid
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261644944P | 2012-05-09 | 2012-05-09 | |
US61/644,944 | 2012-05-09 | ||
US201261737239P | 2012-12-14 | 2012-12-14 | |
US61/737,239 | 2012-12-14 | ||
JP2019221319A JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019221319A Division JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022058682A JP2022058682A (ja) | 2022-04-12 |
JP2022058682A5 true JP2022058682A5 (enrdf_load_stackoverflow) | 2023-01-04 |
Family
ID=49551273
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015511698A Expired - Fee Related JP6608697B2 (ja) | 2012-05-09 | 2013-05-09 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
JP2018086685A Withdrawn JP2018138045A (ja) | 2012-05-09 | 2018-04-27 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
JP2019221319A Pending JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
JP2022007043A Pending JP2022058682A (ja) | 2012-05-09 | 2022-01-20 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015511698A Expired - Fee Related JP6608697B2 (ja) | 2012-05-09 | 2013-05-09 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
JP2018086685A Withdrawn JP2018138045A (ja) | 2012-05-09 | 2018-04-27 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
JP2019221319A Pending JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Country Status (16)
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX369056B (es) | 2012-05-09 | 2019-10-28 | Contrafect Corp | Prevención, interrupción y tratamiento de biopelículas con lisina de bacteriófago. |
RU2018121290A (ru) | 2012-05-09 | 2019-03-06 | Контрафект Корпорейшн | Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий |
RU2725809C2 (ru) | 2014-06-26 | 2020-07-06 | Дзе Рокфеллер Юниверсити | Лизины ацинетобактеров |
AU2016231141B2 (en) * | 2015-03-12 | 2022-03-03 | Micreos Human Health B.V. | Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection |
WO2017049242A2 (en) * | 2015-09-17 | 2017-03-23 | Contrafect Corporation | Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby |
US10851401B2 (en) * | 2016-05-12 | 2020-12-01 | Contrafect Corporation | Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides |
DK3641753T3 (da) | 2017-06-19 | 2022-12-12 | Univ Syddansk | Bacitracin og/eller daptomycin kombineret med cannabidiol til behandling af bakterieinfektioner |
EP3651739A4 (en) * | 2017-07-10 | 2021-04-07 | Contrafect Corporation | BLOOD COMPONENT POTENTIALIZATION OF LYTIC PROTEIN ANTIBACTERIAL ACTIVITY AND RELATED METHODS AND USES |
JP2021513865A (ja) * | 2018-02-26 | 2021-06-03 | コントラフェクト コーポレイション | 修飾PlySs2溶解素及びその使用 |
WO2019246552A1 (en) * | 2018-06-22 | 2019-12-26 | Contrafect Corporation | Lysins and derivatives thereof resensitize staphylococcus aureus and gram-positive bacteria to antibiotics |
CN109668873B (zh) * | 2018-12-05 | 2021-03-16 | 山东恒业生物技术有限公司 | 一种活载体疫苗活性检测装置及其使用方法 |
BR112021015321A2 (pt) * | 2019-02-05 | 2021-10-05 | Elanco Us Inc. | Plataforma de dispensação viva, cassete de expressão, sequência de ácido nucleico, biomolécula, atividade anti-infecciosa, anticorpo, e, método para reduzir a colonização de um animal por uma bactéria patogênica |
MX2021011469A (es) * | 2019-03-22 | 2021-10-22 | Contrafect Corp | Combinacion de lisina(s) y antibiotico(s) para tratar o prevenir endocarditis infecciosa debida a bacterias gram-positivas. |
US20220193186A1 (en) * | 2019-04-11 | 2022-06-23 | Contrafect Corporation | Method of treating and preventing bone and joint infections |
US20230105108A1 (en) * | 2019-12-19 | 2023-04-06 | Georgia State University Research Foundation, Inc. | Compounds for the treatment of bacterial infections and potentiation of antibiotics |
AU2021275048A1 (en) * | 2020-05-19 | 2023-02-02 | Contrafect Corporation | Modified PlySs2 lysins and antibiotic combinations for use against Gram-positive bacteria |
RU2755817C1 (ru) * | 2020-07-22 | 2021-09-21 | Федеральное Государственное бюджетное научное учреждение "Федеральный научный центр биологических систем и агротехнологий российской академии наук" | Способ снижения грамположительной микрофлоры в кишечнике птицы |
KR102528412B1 (ko) * | 2020-09-08 | 2023-05-04 | 클립스비엔씨 주식회사 | 신규한 포도상구균 감염 질환의 예방 또는 치료용 조성물 |
WO2022261360A1 (en) * | 2021-06-09 | 2022-12-15 | Contrafect Corporation | Plyss2 lysins and variants thereof for use against multidrug resistant gram-positive bacteria |
CN115105491B (zh) * | 2022-07-08 | 2023-12-22 | 东北农业大学 | 丝氨酸在制备抑制猪链球菌药物中的用途 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988002781A1 (en) | 1986-10-08 | 1988-04-21 | David Bernstein | Method for exposing group a streptococcal antigens and an improved diagnostic test for the identification of group a streptococci |
CA1315229C (en) | 1987-06-10 | 1993-03-30 | Patrick J. Baker | Chromatographic purification process |
CA2251724A1 (en) * | 1996-04-15 | 1997-10-23 | Paul Averback | Compositions containing bacteriophages and methods of using bacteriophages to treat infections |
US5997862A (en) | 1997-10-31 | 1999-12-07 | New Horizons Diagnostics Corporation | Therapeutic treatment of group A streptococcal infections |
US6248324B1 (en) | 1997-10-31 | 2001-06-19 | Vincent Fischetti | Bacterial phage associated lysing enzymes for treating dermatological infections |
US6264945B1 (en) | 1997-10-31 | 2001-07-24 | Vincent A Fischetti | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
US6254866B1 (en) | 1997-10-31 | 2001-07-03 | New Horizons Diagnostics Corporation | Use of phage associated lytic enzymes for treating bacterial infections of the digestive tract |
US20060292135A1 (en) | 1997-10-31 | 2006-12-28 | Lawrence Loomis | Use of bacterial phage-associated lysing proteins for preventing and treating bacterial infections in humans, animals and fowl |
AU2876799A (en) | 1999-02-25 | 2000-09-14 | New Horizons Diagnostics, Inc. | A means for the prophylactic and therapeutic treatment of streptococcal infections |
US6056955A (en) | 1999-09-14 | 2000-05-02 | Fischetti; Vincent | Topical treatment of streptococcal infections |
US6444813B2 (en) | 2000-02-02 | 2002-09-03 | Pharmacia & Upjohn Company | Linezolid-crystal form II |
EP1501925A4 (en) | 2002-05-17 | 2006-10-25 | New Horizons Diagnostics Corp | IDENTIFICATION OF A LYTIC ENZYME ASSOCIATED WITH A PHAGE TO DETECT AND ELIMINATE RAPIDLY AND SPECIFICALLY BACILLUS ANTHRACIS |
US7569223B2 (en) | 2004-03-22 | 2009-08-04 | The Rockefeller University | Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions |
WO2005089527A2 (en) | 2004-03-24 | 2005-09-29 | The Rockefeller University | Lytic enzymes and spore surface antigen for detection and treatment of bacillus anthracis bacteria and spores |
US8389469B2 (en) | 2005-06-06 | 2013-03-05 | The Rockefeller University | Bacteriophage lysins for Bacillus anthracis |
US7582291B2 (en) | 2005-06-30 | 2009-09-01 | The Rockefeller University | Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria |
EP1917355B1 (en) | 2005-08-24 | 2010-12-08 | The Rockefeller University | Ply-gbs mutant lysins |
US20090053149A1 (en) | 2007-08-24 | 2009-02-26 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Surfactant-based antimicrobial solution for inhalation |
US8840900B2 (en) * | 2008-07-03 | 2014-09-23 | The Rockefeller University | Chimeric bacteriophage lysin with activity against Staphylococci bacteria |
KR101016918B1 (ko) | 2009-01-08 | 2011-02-25 | 주식회사 인트론바이오테크놀로지 | 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질 |
EP2539446B1 (en) | 2010-01-25 | 2017-11-01 | Alere Scarborough Inc. | A25 bacteriophage lysin |
US20120271770A1 (en) * | 2011-04-20 | 2012-10-25 | Visa International Service Association | Managing electronic tokens in a transaction processing system |
EP3252155A1 (en) | 2011-04-21 | 2017-12-06 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
US20140179594A1 (en) | 2011-04-21 | 2014-06-26 | The Rockefeller University | Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock |
WO2012145693A1 (en) | 2011-04-22 | 2012-10-26 | Rks Design, Inc. | Instrument retention assembly |
US20140120074A1 (en) | 2011-04-27 | 2014-05-01 | Lysando Ag | Antimicrobial agents |
RU2018121290A (ru) | 2012-05-09 | 2019-03-06 | Контрафект Корпорейшн | Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий |
MX369056B (es) * | 2012-05-09 | 2019-10-28 | Contrafect Corp | Prevención, interrupción y tratamiento de biopelículas con lisina de bacteriófago. |
-
2013
- 2013-05-09 RU RU2018121290A patent/RU2018121290A/ru unknown
- 2013-05-09 HK HK15112347.8A patent/HK1211484A1/xx unknown
- 2013-05-09 BR BR112014027842A patent/BR112014027842A2/pt not_active IP Right Cessation
- 2013-05-09 CN CN201380036510.8A patent/CN104736172A/zh active Pending
- 2013-05-09 EP EP13787128.1A patent/EP2849782B1/en active Active
- 2013-05-09 KR KR1020237023634A patent/KR20230113404A/ko not_active Withdrawn
- 2013-05-09 WO PCT/US2013/040329 patent/WO2013170015A1/en not_active Application Discontinuation
- 2013-05-09 ES ES13787128T patent/ES2784136T3/es active Active
- 2013-05-09 KR KR1020217031525A patent/KR20210121313A/ko not_active Ceased
- 2013-05-09 RU RU2014149351A patent/RU2659208C2/ru active
- 2013-05-09 EP EP20158873.8A patent/EP3685851A1/en active Pending
- 2013-05-09 DK DK13787128.1T patent/DK2849782T3/da active
- 2013-05-09 US US14/399,575 patent/US10813983B2/en not_active Expired - Fee Related
- 2013-05-09 CA CA2872902A patent/CA2872902A1/en active Pending
- 2013-05-09 KR KR1020147034614A patent/KR102310387B1/ko not_active Expired - Fee Related
- 2013-05-09 JP JP2015511698A patent/JP6608697B2/ja not_active Expired - Fee Related
- 2013-05-09 IL IL308477A patent/IL308477A/en unknown
- 2013-05-09 IN IN2437MUN2014 patent/IN2014MN02437A/en unknown
- 2013-05-09 AU AU2013259512A patent/AU2013259512B2/en not_active Ceased
- 2013-05-09 IL IL235527A patent/IL235527B2/en unknown
- 2013-05-09 MX MX2014013586A patent/MX389127B/es unknown
- 2013-06-04 US US13/909,618 patent/US9889181B2/en active Active
-
2014
- 2014-11-07 MX MX2021011843A patent/MX2021011843A/es unknown
-
2017
- 2017-12-20 US US15/848,886 patent/US20180221456A1/en not_active Abandoned
-
2018
- 2018-04-24 AU AU2018202845A patent/AU2018202845B2/en not_active Ceased
- 2018-04-27 JP JP2018086685A patent/JP2018138045A/ja not_active Withdrawn
-
2019
- 2019-12-06 JP JP2019221319A patent/JP2020054370A/ja active Pending
-
2020
- 2020-05-21 IL IL274832A patent/IL274832A/en unknown
- 2020-09-16 AU AU2020233683A patent/AU2020233683A1/en not_active Abandoned
- 2020-09-25 US US17/033,195 patent/US20210008175A1/en not_active Abandoned
-
2021
- 2021-01-05 US US17/141,692 patent/US20210128696A1/en not_active Abandoned
-
2022
- 2022-01-20 JP JP2022007043A patent/JP2022058682A/ja active Pending
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