JP2022058682A5 - - Google Patents

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Publication number
JP2022058682A5
JP2022058682A5 JP2022007043A JP2022007043A JP2022058682A5 JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5 JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5
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JP
Japan
Prior art keywords
synergistic combination
gram
composition
amino acid
antibiotics
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Pending
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JP2022007043A
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English (en)
Japanese (ja)
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JP2022058682A (ja
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Priority claimed from JP2019221319A external-priority patent/JP2020054370A/ja
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Publication of JP2022058682A publication Critical patent/JP2022058682A/ja
Publication of JP2022058682A5 publication Critical patent/JP2022058682A5/ja
Pending legal-status Critical Current

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JP2022007043A 2012-05-09 2022-01-20 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ Pending JP2022058682A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261644944P 2012-05-09 2012-05-09
US61/644,944 2012-05-09
US201261737239P 2012-12-14 2012-12-14
US61/737,239 2012-12-14
JP2019221319A JP2020054370A (ja) 2012-05-09 2019-12-06 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ

Related Parent Applications (1)

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JP2019221319A Division JP2020054370A (ja) 2012-05-09 2019-12-06 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ

Publications (2)

Publication Number Publication Date
JP2022058682A JP2022058682A (ja) 2022-04-12
JP2022058682A5 true JP2022058682A5 (enrdf_load_stackoverflow) 2023-01-04

Family

ID=49551273

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015511698A Expired - Fee Related JP6608697B2 (ja) 2012-05-09 2013-05-09 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
JP2018086685A Withdrawn JP2018138045A (ja) 2012-05-09 2018-04-27 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
JP2019221319A Pending JP2020054370A (ja) 2012-05-09 2019-12-06 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
JP2022007043A Pending JP2022058682A (ja) 2012-05-09 2022-01-20 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2015511698A Expired - Fee Related JP6608697B2 (ja) 2012-05-09 2013-05-09 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
JP2018086685A Withdrawn JP2018138045A (ja) 2012-05-09 2018-04-27 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
JP2019221319A Pending JP2020054370A (ja) 2012-05-09 2019-12-06 グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ

Country Status (16)

Country Link
US (5) US10813983B2 (enrdf_load_stackoverflow)
EP (2) EP2849782B1 (enrdf_load_stackoverflow)
JP (4) JP6608697B2 (enrdf_load_stackoverflow)
KR (3) KR20230113404A (enrdf_load_stackoverflow)
CN (1) CN104736172A (enrdf_load_stackoverflow)
AU (3) AU2013259512B2 (enrdf_load_stackoverflow)
BR (1) BR112014027842A2 (enrdf_load_stackoverflow)
CA (1) CA2872902A1 (enrdf_load_stackoverflow)
DK (1) DK2849782T3 (enrdf_load_stackoverflow)
ES (1) ES2784136T3 (enrdf_load_stackoverflow)
HK (1) HK1211484A1 (enrdf_load_stackoverflow)
IL (3) IL308477A (enrdf_load_stackoverflow)
IN (1) IN2014MN02437A (enrdf_load_stackoverflow)
MX (2) MX389127B (enrdf_load_stackoverflow)
RU (2) RU2018121290A (enrdf_load_stackoverflow)
WO (1) WO2013170015A1 (enrdf_load_stackoverflow)

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RU2018121290A (ru) 2012-05-09 2019-03-06 Контрафект Корпорейшн Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий
RU2725809C2 (ru) 2014-06-26 2020-07-06 Дзе Рокфеллер Юниверсити Лизины ацинетобактеров
AU2016231141B2 (en) * 2015-03-12 2022-03-03 Micreos Human Health B.V. Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection
WO2017049242A2 (en) * 2015-09-17 2017-03-23 Contrafect Corporation Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby
US10851401B2 (en) * 2016-05-12 2020-12-01 Contrafect Corporation Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides
DK3641753T3 (da) 2017-06-19 2022-12-12 Univ Syddansk Bacitracin og/eller daptomycin kombineret med cannabidiol til behandling af bakterieinfektioner
EP3651739A4 (en) * 2017-07-10 2021-04-07 Contrafect Corporation BLOOD COMPONENT POTENTIALIZATION OF LYTIC PROTEIN ANTIBACTERIAL ACTIVITY AND RELATED METHODS AND USES
JP2021513865A (ja) * 2018-02-26 2021-06-03 コントラフェクト コーポレイション 修飾PlySs2溶解素及びその使用
WO2019246552A1 (en) * 2018-06-22 2019-12-26 Contrafect Corporation Lysins and derivatives thereof resensitize staphylococcus aureus and gram-positive bacteria to antibiotics
CN109668873B (zh) * 2018-12-05 2021-03-16 山东恒业生物技术有限公司 一种活载体疫苗活性检测装置及其使用方法
BR112021015321A2 (pt) * 2019-02-05 2021-10-05 Elanco Us Inc. Plataforma de dispensação viva, cassete de expressão, sequência de ácido nucleico, biomolécula, atividade anti-infecciosa, anticorpo, e, método para reduzir a colonização de um animal por uma bactéria patogênica
MX2021011469A (es) * 2019-03-22 2021-10-22 Contrafect Corp Combinacion de lisina(s) y antibiotico(s) para tratar o prevenir endocarditis infecciosa debida a bacterias gram-positivas.
US20220193186A1 (en) * 2019-04-11 2022-06-23 Contrafect Corporation Method of treating and preventing bone and joint infections
US20230105108A1 (en) * 2019-12-19 2023-04-06 Georgia State University Research Foundation, Inc. Compounds for the treatment of bacterial infections and potentiation of antibiotics
AU2021275048A1 (en) * 2020-05-19 2023-02-02 Contrafect Corporation Modified PlySs2 lysins and antibiotic combinations for use against Gram-positive bacteria
RU2755817C1 (ru) * 2020-07-22 2021-09-21 Федеральное Государственное бюджетное научное учреждение "Федеральный научный центр биологических систем и агротехнологий российской академии наук" Способ снижения грамположительной микрофлоры в кишечнике птицы
KR102528412B1 (ko) * 2020-09-08 2023-05-04 클립스비엔씨 주식회사 신규한 포도상구균 감염 질환의 예방 또는 치료용 조성물
WO2022261360A1 (en) * 2021-06-09 2022-12-15 Contrafect Corporation Plyss2 lysins and variants thereof for use against multidrug resistant gram-positive bacteria
CN115105491B (zh) * 2022-07-08 2023-12-22 东北农业大学 丝氨酸在制备抑制猪链球菌药物中的用途

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