JP2022023144A5 - - Google Patents
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- Publication number
- JP2022023144A5 JP2022023144A5 JP2021170086A JP2021170086A JP2022023144A5 JP 2022023144 A5 JP2022023144 A5 JP 2022023144A5 JP 2021170086 A JP2021170086 A JP 2021170086A JP 2021170086 A JP2021170086 A JP 2021170086A JP 2022023144 A5 JP2022023144 A5 JP 2022023144A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cas9 protein
- guide rna
- sequence
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762564478P | 2017-09-28 | 2017-09-28 | |
| US62/564,478 | 2017-09-28 | ||
| US201762565868P | 2017-09-29 | 2017-09-29 | |
| US62/565,868 | 2017-09-29 | ||
| JP2020513755A JP2020536501A (ja) | 2017-09-28 | 2018-09-27 | 遺伝子発現調節のための人為的なゲノム操作 |
| PCT/KR2018/011424 WO2019066490A2 (ko) | 2017-09-28 | 2018-09-27 | 유전자 발현 조절을 위한 인위적인 게놈 조작 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513755A Division JP2020536501A (ja) | 2017-09-28 | 2018-09-27 | 遺伝子発現調節のための人為的なゲノム操作 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022023144A JP2022023144A (ja) | 2022-02-07 |
| JP2022023144A5 true JP2022023144A5 (https=) | 2022-07-12 |
| JP7440043B2 JP7440043B2 (ja) | 2024-02-28 |
Family
ID=65902054
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513755A Pending JP2020536501A (ja) | 2017-09-28 | 2018-09-27 | 遺伝子発現調節のための人為的なゲノム操作 |
| JP2021170086A Active JP7440043B2 (ja) | 2017-09-28 | 2021-10-18 | 遺伝子発現調節のための人為的なゲノム操作 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513755A Pending JP2020536501A (ja) | 2017-09-28 | 2018-09-27 | 遺伝子発現調節のための人為的なゲノム操作 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3690047A4 (https=) |
| JP (2) | JP2020536501A (https=) |
| KR (1) | KR102670361B1 (https=) |
| CN (2) | CN118581083A (https=) |
| AU (1) | AU2018339164B2 (https=) |
| BR (1) | BR112020006428A2 (https=) |
| RU (2) | RU2767201C2 (https=) |
| SG (1) | SG11202002130WA (https=) |
| WO (1) | WO2019066490A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110577969B (zh) * | 2019-08-08 | 2022-07-22 | 复旦大学 | CRISPR/Sa-SlugCas9基因编辑系统及其应用 |
| CN110577970B (zh) * | 2019-08-08 | 2022-11-18 | 复旦大学 | CRISPR/Sa-SlutCas9基因编辑系统及其应用 |
| CN110577972B (zh) * | 2019-08-08 | 2022-10-11 | 复旦大学 | CRISPR/Sa-ShaCas9基因编辑系统及其应用 |
| EP4091635A4 (en) * | 2020-01-14 | 2024-02-21 | Toolgen Incorporated | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE AND USE THEREOF |
| AU2021390471A1 (en) * | 2020-12-01 | 2023-06-29 | Research Institute At Nationwide Children's Hospital | Products and methods for inhibition of expression of peripheral myelin protein-22 |
| US12516347B2 (en) | 2021-02-02 | 2026-01-06 | Limagrain Europe | Linkage of a distal promoter to a gene of interest by gene editing to modify gene expression |
| CN114426982B (zh) * | 2022-02-22 | 2024-03-22 | 上海交通大学 | 一种细胞代谢重编程的方法及其应用 |
| WO2024053964A1 (ko) * | 2022-09-06 | 2024-03-14 | 주식회사 툴젠 | 캄필로박터 제주니 유래 cas9의 가이드 rna 구조변화를 통한 유전자교정 향상 시스템 |
| CN116536357A (zh) * | 2023-04-17 | 2023-08-04 | 中国医学科学院输血研究所 | 构建CRISPR/Cas12a中sgRNA剪切活性筛选系统的方法 |
| WO2025079278A1 (ja) * | 2023-10-10 | 2025-04-17 | 国立大学法人 東京医科歯科大学 | シャルコー・マリー・トゥース病の処置剤 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4357457B1 (en) * | 2012-10-23 | 2024-10-16 | Toolgen Incorporated | Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof |
| CN105121648B (zh) * | 2012-12-12 | 2021-05-07 | 布罗德研究所有限公司 | 用于序列操纵的系统、方法和优化的指导组合物的工程化 |
| SI2986729T1 (sl) * | 2013-04-16 | 2019-02-28 | Regeneron Pharmaceuticals, Inc. | Ciljana sprememba genoma podgane |
| KR20160019553A (ko) | 2013-06-17 | 2016-02-19 | 더 브로드 인스티튜트, 인코퍼레이티드 | 유사분열 후 세포의 질병 및 장애를 표적화하고 모델링하기 위한 시스템, 방법 및 조성물의 전달, 유전자 조작 및 최적화 |
| US9388430B2 (en) * | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| WO2015048577A2 (en) * | 2013-09-27 | 2015-04-02 | Editas Medicine, Inc. | Crispr-related methods and compositions |
| BR112016013207A2 (pt) * | 2013-12-12 | 2017-09-26 | Massachusetts Inst Technology | administração, uso e aplicações terapêuticas dos sistemas crispr-cas e composições para o hbv e distúrbios e doenças virais |
| EP3341727B1 (en) * | 2015-08-25 | 2022-08-10 | Duke University | Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases |
| WO2017053431A2 (en) | 2015-09-21 | 2017-03-30 | Arcturus Therapeutics, Inc. | Allele selective gene editing and uses thereof |
| ES2905558T3 (es) * | 2015-11-13 | 2022-04-11 | Avellino Lab Usa Inc | Procedimientos para el tratamiento de las distrofias corneales |
| WO2018088694A2 (ko) * | 2016-11-14 | 2018-05-17 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| JP7416406B2 (ja) * | 2016-12-08 | 2024-01-17 | ケース ウェスタン リザーブ ユニバーシティ | 機能的ミエリン産生を増進させるための方法および組成物 |
-
2018
- 2018-09-27 SG SG11202002130WA patent/SG11202002130WA/en unknown
- 2018-09-27 WO PCT/KR2018/011424 patent/WO2019066490A2/ko not_active Ceased
- 2018-09-27 JP JP2020513755A patent/JP2020536501A/ja active Pending
- 2018-09-27 CN CN202410521102.1A patent/CN118581083A/zh active Pending
- 2018-09-27 KR KR1020180114900A patent/KR102670361B1/ko active Active
- 2018-09-27 AU AU2018339164A patent/AU2018339164B2/en active Active
- 2018-09-27 RU RU2020114785A patent/RU2767201C2/ru active
- 2018-09-27 RU RU2022103641A patent/RU2022103641A/ru unknown
- 2018-09-27 BR BR112020006428-9A patent/BR112020006428A2/pt not_active Application Discontinuation
- 2018-09-27 EP EP18862957.0A patent/EP3690047A4/en active Pending
- 2018-09-27 CN CN201880076752.2A patent/CN111527208B/zh active Active
-
2021
- 2021-10-18 JP JP2021170086A patent/JP7440043B2/ja active Active
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