JP2021533179A5 - - Google Patents

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Publication number
JP2021533179A5
JP2021533179A5 JP2021507992A JP2021507992A JP2021533179A5 JP 2021533179 A5 JP2021533179 A5 JP 2021533179A5 JP 2021507992 A JP2021507992 A JP 2021507992A JP 2021507992 A JP2021507992 A JP 2021507992A JP 2021533179 A5 JP2021533179 A5 JP 2021533179A5
Authority
JP
Japan
Prior art keywords
amino
pyrazine
carboxamide
methyl
pyridine
Prior art date
Application number
JP2021507992A
Other languages
English (en)
Japanese (ja)
Other versions
JP7540996B2 (ja
JPWO2020035052A5 (https=
JP2021533179A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CN2019/100996 external-priority patent/WO2020035052A1/en
Publication of JP2021533179A publication Critical patent/JP2021533179A/ja
Publication of JP2021533179A5 publication Critical patent/JP2021533179A5/ja
Publication of JPWO2020035052A5 publication Critical patent/JPWO2020035052A5/ja
Application granted granted Critical
Publication of JP7540996B2 publication Critical patent/JP7540996B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021507992A 2018-08-17 2019-08-16 ピラジン化合物およびその使用 Active JP7540996B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2018/101006 2018-08-17
CN2018101006 2018-08-17
PCT/CN2019/100996 WO2020035052A1 (en) 2018-08-17 2019-08-16 Pyrazine compounds and uses thereof

Publications (4)

Publication Number Publication Date
JP2021533179A JP2021533179A (ja) 2021-12-02
JP2021533179A5 true JP2021533179A5 (https=) 2022-08-04
JPWO2020035052A5 JPWO2020035052A5 (https=) 2022-08-04
JP7540996B2 JP7540996B2 (ja) 2024-08-27

Family

ID=69524697

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021507992A Active JP7540996B2 (ja) 2018-08-17 2019-08-16 ピラジン化合物およびその使用

Country Status (12)

Country Link
US (3) US10898481B2 (https=)
EP (1) EP3837250A4 (https=)
JP (1) JP7540996B2 (https=)
KR (1) KR102816365B1 (https=)
CN (1) CN112055709A (https=)
AR (1) AR115985A1 (https=)
AU (1) AU2019323035B2 (https=)
BR (1) BR112021002895A2 (https=)
CA (1) CA3107365A1 (https=)
MX (2) MX2021001884A (https=)
TW (1) TW202023559A (https=)
WO (1) WO2020035052A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018584A1 (en) 2017-07-18 2019-01-24 GiraFpharma LLC HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
AU2019323035B2 (en) * 2018-08-17 2024-11-07 Dizal (Jiangsu) Pharmaceutical Co., Ltd. Pyrazine compounds and uses thereof
JP2022517418A (ja) * 2019-01-18 2022-03-08 ニューベイション・バイオ・インコーポレイテッド アデノシンアンタゴニストとしてのヘテロ環式化合物
EP3911323A4 (en) * 2019-01-18 2022-11-16 Nuvation Bio Inc. HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
EP3911324A4 (en) 2019-01-18 2022-08-17 Nuvation Bio Inc. 1,8-NAPHTHYRIDINONE COMPOUNDS AND THEIR USES
WO2021146629A1 (en) * 2020-01-17 2021-07-22 Nuvation Bio Inc. Heterocyclic compounds as adenosine antagonists
WO2021146631A1 (en) * 2020-01-17 2021-07-22 Nuvation Bio Inc. Heterocyclic compounds as adenosine antagonists
CA3182410A1 (en) 2020-05-04 2021-11-11 Volastra Therapeutics, Inc. Imino sulfanone inhibitors of enpp1
US12091412B2 (en) 2020-06-16 2024-09-17 Volastra Therapeutics, Inc. Heterocyclic inhibitors of ENPP1
KR102621694B1 (ko) * 2022-09-15 2024-01-08 주식회사 스탠다임 아데노신 a2a 수용체 길항제 및 이의 용도
US11987581B1 (en) 2023-12-19 2024-05-21 King Faisal University Imidazo[1,2-c]pyrido[3,4-e]pyrimidine-2-carboxylic acids as CK2 inhibitors
US11964974B1 (en) 2024-01-08 2024-04-23 King Faisal University Imidazo[1,2-c]pyrido[3,4-e]pyrimidine-3-carboxylic acids as CK2 inhibitors
WO2025191185A1 (en) * 2024-03-15 2025-09-18 Domain Therapeutics Azine-based compounds as par-2 inhibitors and therapeutic uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2543644A1 (en) 2003-10-27 2005-05-06 Astellas Pharma Inc. Pyrazine derivatives and pharmaceutical use thereof
CN1871231A (zh) * 2003-10-27 2006-11-29 安斯泰来制药有限公司 吡嗪衍生物及其医药用途
CN1938296A (zh) * 2004-04-01 2007-03-28 安斯泰来制药有限公司 作为腺苷拮抗剂的吡嗪衍生物及其制药用途
WO2019018584A1 (en) * 2017-07-18 2019-01-24 GiraFpharma LLC HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
AU2019323035B2 (en) * 2018-08-17 2024-11-07 Dizal (Jiangsu) Pharmaceutical Co., Ltd. Pyrazine compounds and uses thereof

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