JP2021532058A5 - - Google Patents
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- Publication number
- JP2021532058A5 JP2021532058A5 JP2020552889A JP2020552889A JP2021532058A5 JP 2021532058 A5 JP2021532058 A5 JP 2021532058A5 JP 2020552889 A JP2020552889 A JP 2020552889A JP 2020552889 A JP2020552889 A JP 2020552889A JP 2021532058 A5 JP2021532058 A5 JP 2021532058A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- antibody
- variable region
- chain variable
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024027487A JP2024063083A (ja) | 2018-07-25 | 2024-02-27 | 抗ｔｉｇｉｔ抗体及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810823583 | 2018-07-25 | ||
| CN201810823583.6 | 2018-07-25 | ||
| PCT/CN2019/097665 WO2020020281A1 (zh) | 2018-07-25 | 2019-07-25 | 抗tigit抗体及其用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024027487A Division JP2024063083A (ja) | 2018-07-25 | 2024-02-27 | 抗ｔｉｇｉｔ抗体及びその使用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021532058A JP2021532058A (ja) | 2021-11-25 |
| JPWO2020020281A5 JPWO2020020281A5 (https=) | 2022-07-28 |
| JP2021532058A5 true JP2021532058A5 (https=) | 2022-07-28 |
| JP7524065B2 JP7524065B2 (ja) | 2024-07-29 |
Family
ID=69181312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552889A Active JP7524065B2 (ja) | 2018-07-25 | 2019-07-25 | 抗ｔｉｇｉｔ抗体及びその使用 |
| JP2024027487A Withdrawn JP2024063083A (ja) | 2018-07-25 | 2024-02-27 | 抗ｔｉｇｉｔ抗体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024027487A Withdrawn JP2024063083A (ja) | 2018-07-25 | 2024-02-27 | 抗ｔｉｇｉｔ抗体及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11370837B2 (https=) |
| EP (1) | EP3838289A4 (https=) |
| JP (2) | JP7524065B2 (https=) |
| KR (1) | KR20210040827A (https=) |
| CN (1) | CN112135626B (https=) |
| AU (1) | AU2019310803B2 (https=) |
| BR (1) | BR112021001201A2 (https=) |
| CA (1) | CA3092456C (https=) |
| SG (1) | SG11202100746WA (https=) |
| TW (1) | TWI754157B (https=) |
| WO (1) | WO2020020281A1 (https=) |
| ZA (1) | ZA202100676B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021113831A1 (en) | 2019-12-05 | 2021-06-10 | Compugen Ltd. | Anti-pvrig and anti-tigit antibodies for enhanced nk-cell based tumor killing |
| AU2021211799A1 (en) * | 2020-01-21 | 2022-08-11 | Innovent Biologics (Suzhou) Co., Ltd. | Recombinant fully human anti-TIGIT monoclonal antibody preparations, preparation method therefor and use thereof |
| CN111995681B (zh) * | 2020-05-09 | 2022-03-08 | 华博生物医药技术（上海）有限公司 | 抗tigit的抗体、其制备方法和应用 |
| BR112022024221A2 (pt) | 2020-06-02 | 2022-12-20 | Arcus Biosciences Inc | Anticorpos para tigit |
| CN115916348A (zh) | 2020-06-18 | 2023-04-04 | 基因泰克公司 | 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗 |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷 |
| US20240262915A1 (en) * | 2020-09-22 | 2024-08-08 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Anti-tigit antibody and double antibody and their application |
| EP4238991A4 (en) * | 2020-11-23 | 2024-05-15 | Guangdong Fapon Biopharma Inc. | ANTI-TIGIT ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF |
| KR20220082776A (ko) * | 2020-12-10 | 2022-06-17 | 주식회사 유틸렉스 | 항-tigit 항체 및 이의 용도 |
| WO2022232016A2 (en) * | 2021-04-26 | 2022-11-03 | Memorial Sloan-Kettering Cancer Center | Chimeric receptors targeting adgre2 and/or clec12a and uses thereof |
| CN117916263B (zh) | 2021-05-10 | 2025-04-25 | 美帝马布生物公司 | 抗tigit抗体及其用途 |
| CN118871463A (zh) | 2021-07-28 | 2024-10-29 | 基因泰克公司 | 用于治疗癌症的方法和组合物 |
| CN117794952A (zh) * | 2021-08-09 | 2024-03-29 | 普米斯生物技术(珠海)有限公司 | 抗tigit抗体及其用途 |
| TW202321308A (zh) | 2021-09-30 | 2023-06-01 | 美商建南德克公司 | 使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法 |
| WO2023108609A1 (en) * | 2021-12-17 | 2023-06-22 | Shanghai Nigene Biological Science And Technology Co., Ltd. | Tigit antibodies and uses thereof |
| CN116685685A (zh) * | 2021-12-31 | 2023-09-01 | 南京维立志博生物科技有限公司 | Tigit单域抗体以及基于其的双特异性抗体 |
| PE20251671A1 (es) | 2022-03-15 | 2025-06-30 | Compugen Ltd | Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer |
| CA3256561A1 (en) | 2022-05-02 | 2023-11-09 | Arcus Biosciences, Inc. | Anti-tigit antibodies and their uses |
| EP4537107A2 (en) | 2022-06-07 | 2025-04-16 | Genentech, Inc. | Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody |
| US20240309052A1 (en) * | 2023-03-16 | 2024-09-19 | Sunnybrook Research Institute | Constructs, use and methods thereof |
| TW202515608A (zh) | 2023-06-26 | 2025-04-16 | 以色列商坎布根有限公司 | Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途 |
| CN121003695A (zh) * | 2024-05-24 | 2025-11-25 | 百奥泰生物制药股份有限公司 | 抗tigit抗体和抗pd-1抗体联合治疗肿瘤 |
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| EP0154316B1 (en) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| GB9108652D0 (en) | 1991-04-23 | 1991-06-12 | Antisoma Ltd | Immunoreactive compounds |
| WO1993006217A1 (en) | 1991-09-19 | 1993-04-01 | Genentech, Inc. | EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES |
| DE69332643T2 (de) | 1992-09-16 | 2003-11-27 | The Scripps Research Institute, La Jolla | Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus |
| JP3919830B2 (ja) | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片 |
| AU1866895A (en) | 1994-01-04 | 1995-08-01 | Scripps Research Institute, The | Human monoclonal antibodies to herpes simplex virus and methods therefor |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
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| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
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| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
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| TW201100543A (en) | 2009-05-27 | 2011-01-01 | Hoffmann La Roche | Tri-or tetraspecific antibodies |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
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| EP3126394B1 (en) | 2014-03-31 | 2019-10-30 | F.Hoffmann-La Roche Ag | Anti-ox40 antibodies and methods of use |
| AU2015305754B2 (en) * | 2014-08-19 | 2018-10-25 | Merck Sharp & Dohme Llc | Anti-tigit antibodies |
| CN107207594B (zh) * | 2014-12-23 | 2019-05-07 | 百时美施贵宝公司 | 针对tigit的抗体 |
| TWI715587B (zh) * | 2015-05-28 | 2021-01-11 | 美商安可美德藥物股份有限公司 | Ｔｉｇｉｔ結合劑和彼之用途 |
| WO2017024465A1 (en) | 2015-08-10 | 2017-02-16 | Innovent Biologics (Suzhou) Co., Ltd. | Pd-1 antibodies |
| EP3334757A4 (en) * | 2015-08-14 | 2019-04-03 | Merck Sharp & Dohme Corp. | ANTI-Tigit ANTIBODY |
| CN108137691B (zh) * | 2015-09-02 | 2021-10-19 | 耶路撒冷希伯来大学伊萨姆研究发展有限公司 | 特异性针对人类t-细胞免疫球蛋白和itim结构域(tigit)的抗体 |
| CA2994858C (en) | 2015-09-25 | 2024-01-23 | Genentech, Inc. | Anti-tigit antibodies and methods of use |
| PL3356413T3 (pl) * | 2015-10-01 | 2022-04-19 | Potenza Therapeutics, Inc. | Białka anty-tigit wiążące antygen oraz sposoby ich zastosowania |
| WO2017132827A1 (en) | 2016-02-02 | 2017-08-10 | Innovent Biologics (Suzhou) Co., Ltd. | Pd-1 antibodies |
| WO2017152088A1 (en) * | 2016-03-04 | 2017-09-08 | JN Biosciences, LLC | Antibodies to tigit |
-
2019
- 2019-07-25 KR KR1020207028253A patent/KR20210040827A/ko not_active Withdrawn
- 2019-07-25 CA CA3092456A patent/CA3092456C/en active Active
- 2019-07-25 BR BR112021001201-0A patent/BR112021001201A2/pt unknown
- 2019-07-25 TW TW108126351A patent/TWI754157B/zh not_active IP Right Cessation
- 2019-07-25 US US16/965,687 patent/US11370837B2/en active Active
- 2019-07-25 EP EP19842191.9A patent/EP3838289A4/en not_active Withdrawn
- 2019-07-25 WO PCT/CN2019/097665 patent/WO2020020281A1/zh not_active Ceased
- 2019-07-25 JP JP2020552889A patent/JP7524065B2/ja active Active
- 2019-07-25 AU AU2019310803A patent/AU2019310803B2/en not_active Ceased
- 2019-07-25 SG SG11202100746WA patent/SG11202100746WA/en unknown
- 2019-07-25 CN CN201980022679.5A patent/CN112135626B/zh active Active
-
2021
- 2021-01-29 ZA ZA2021/00676A patent/ZA202100676B/en unknown
-
2024
- 2024-02-27 JP JP2024027487A patent/JP2024063083A/ja not_active Withdrawn
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