JP2025500796A5 - - Google Patents
Info
- Publication number
- JP2025500796A5 JP2025500796A5 JP2024534342A JP2024534342A JP2025500796A5 JP 2025500796 A5 JP2025500796 A5 JP 2025500796A5 JP 2024534342 A JP2024534342 A JP 2024534342A JP 2024534342 A JP2024534342 A JP 2024534342A JP 2025500796 A5 JP2025500796 A5 JP 2025500796A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- cdr1
- cdr2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163287394P | 2021-12-08 | 2021-12-08 | |
| US63/287,394 | 2021-12-08 | ||
| US202163288479P | 2021-12-10 | 2021-12-10 | |
| US63/288,479 | 2021-12-10 | ||
| US202263421052P | 2022-10-31 | 2022-10-31 | |
| US63/421,052 | 2022-10-31 | ||
| PCT/US2022/081076 WO2023107994A1 (en) | 2021-12-08 | 2022-12-07 | Anti-mutant calreticulin (calr) antibodies and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025500796A JP2025500796A (ja) | 2025-01-15 |
| JP2025500796A5 true JP2025500796A5 (https=) | 2026-04-08 |
Family
ID=84943209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024534342A Pending JP2025500796A (ja) | 2021-12-08 | 2022-12-07 | 抗変異体カルレチクリン（ｃａｌｒ）抗体及びその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20230272055A1 (https=) |
| EP (1) | EP4444343A1 (https=) |
| JP (1) | JP2025500796A (https=) |
| KR (1) | KR20240127992A (https=) |
| AU (1) | AU2022407445A1 (https=) |
| CA (1) | CA3241889A1 (https=) |
| CL (2) | CL2024001654A1 (https=) |
| CO (1) | CO2024009042A2 (https=) |
| CR (1) | CR20240277A (https=) |
| DO (1) | DOP2024000110A (https=) |
| GE (1) | GEAP202416555A (https=) |
| IL (1) | IL313366A (https=) |
| JO (1) | JOP20240122A1 (https=) |
| MX (1) | MX2024006954A (https=) |
| PE (1) | PE20241998A1 (https=) |
| TW (1) | TW202330623A (https=) |
| UY (1) | UY40062A (https=) |
| WO (1) | WO2023107994A1 (https=) |
| ZA (1) | ZA202404295B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117467004B (zh) * | 2023-10-09 | 2024-06-21 | 武汉爱博泰克生物科技有限公司 | 抗人钙网膜蛋白的兔单克隆抗体及其应用 |
| WO2025096716A1 (en) * | 2023-11-01 | 2025-05-08 | Incyte Corporation | Anti-mutant calreticulin (calr) antibody-drug conjugates and uses thereof |
| WO2026013015A1 (en) * | 2024-07-09 | 2026-01-15 | Merus N.V. | Multispecific binding moieties comprising calr and cd3 binding domains |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5156840A (en) | 1982-03-09 | 1992-10-20 | Cytogen Corporation | Amine-containing porphyrin derivatives |
| US5057313A (en) | 1986-02-25 | 1991-10-15 | The Center For Molecular Medicine And Immunology | Diagnostic and therapeutic antibody conjugates |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| ATE207080T1 (de) | 1991-11-25 | 2001-11-15 | Enzon Inc | Multivalente antigen-bindende proteine |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| AR054416A1 (es) | 2004-12-22 | 2007-06-27 | Incyte Corp | Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas. |
| KR101763656B1 (ko) | 2009-06-29 | 2017-08-01 | 인사이트 홀딩스 코포레이션 | Ｐｉ3ｋ 저해물질로서의 피리미디논 |
| US8759359B2 (en) | 2009-12-18 | 2014-06-24 | Incyte Corporation | Substituted heteroaryl fused derivatives as PI3K inhibitors |
| WO2011163195A1 (en) | 2010-06-21 | 2011-12-29 | Incyte Corporation | Fused pyrrole derivatives as pi3k inhibitors |
| US9034884B2 (en) | 2010-11-19 | 2015-05-19 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors |
| US9108984B2 (en) | 2011-03-14 | 2015-08-18 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors |
| CN103797010B (zh) | 2011-06-20 | 2016-02-24 | 因塞特控股公司 | 作为jak抑制剂的氮杂环丁烷基苯基、吡啶基或吡嗪基甲酰胺衍生物 |
| TW201313721A (zh) | 2011-08-18 | 2013-04-01 | Incyte Corp | 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物 |
| TWI646099B (zh) | 2012-11-01 | 2019-01-01 | 英塞特控股公司 | 作爲ｊａｋ抑制劑之三環稠合噻吩衍生物 |
| WO2016087514A1 (en) | 2014-12-02 | 2016-06-09 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies |
| EP3765517A1 (en) | 2018-03-14 | 2021-01-20 | Elstar Therapeutics, Inc. | Multifunctional molecules that bind to calreticulin and uses thereof |
| SG11202108494YA (en) * | 2019-02-28 | 2021-09-29 | Juntendo Educational Found | Antibodies that bind to cleaved form of mutant calreticulin, and diagnostic, preventive, or therapeutic agent for myeloproliferative neoplasm |
-
2022
- 2022-12-07 GE GEAP202416555A patent/GEAP202416555A/en unknown
- 2022-12-07 MX MX2024006954A patent/MX2024006954A/es unknown
- 2022-12-07 KR KR1020247022555A patent/KR20240127992A/ko active Pending
- 2022-12-07 US US18/062,924 patent/US20230272055A1/en active Pending
- 2022-12-07 AU AU2022407445A patent/AU2022407445A1/en active Pending
- 2022-12-07 JP JP2024534342A patent/JP2025500796A/ja active Pending
- 2022-12-07 CR CR20240277A patent/CR20240277A/es unknown
- 2022-12-07 CA CA3241889A patent/CA3241889A1/en active Pending
- 2022-12-07 EP EP22843595.4A patent/EP4444343A1/en active Pending
- 2022-12-07 TW TW111146965A patent/TW202330623A/zh unknown
- 2022-12-07 IL IL313366A patent/IL313366A/en unknown
- 2022-12-07 UY UY0001040062A patent/UY40062A/es unknown
- 2022-12-07 WO PCT/US2022/081076 patent/WO2023107994A1/en not_active Ceased
- 2022-12-07 PE PE2024001321A patent/PE20241998A1/es unknown
-
2024
- 2024-05-29 JO JOJO/P/2024/0122A patent/JOP20240122A1/ar unknown
- 2024-05-31 ZA ZA2024/04295A patent/ZA202404295B/en unknown
- 2024-06-03 CL CL2024001654A patent/CL2024001654A1/es unknown
- 2024-06-06 DO DO2024000110A patent/DOP2024000110A/es unknown
- 2024-07-08 CO CONC2024/0009042A patent/CO2024009042A2/es unknown
-
2025
- 2025-01-24 CL CL2025000229A patent/CL2025000229A1/es unknown
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